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84 Companies |
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113 Products |
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113 Products |
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110 Mechanisms of Action |
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3 Trials |
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2476 News |
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- |||| Valcyte (valganciclovir) / Roche, Mitsubishi Tanabe, Cytovene (ganciclovir) / Roche
Trial completion, Trial initiation date: GRAIL: Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure (clinicaltrials.gov) - Sep 13, 2017
P2, N=160, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed | Initiation date: Sep 2011 --> Mar 2011
- | Enrollment change, Trial primary completion date: Factors Associated With Chronic Respiratory Failure in Obesity (clinicaltrials.gov) - Sep 12, 2017
P=N/A, N=78, Completed, Sponsor: Oxford University Hospitals NHS Trust
Active, not recruiting --> Completed | Initiation date: Sep 2011 --> Mar 2011 N=60 --> 78 | Trial primary completion date: Jun 2012 --> Oct 2015
- ||||||| Trial completion: Stimulation Therapy for Apnea Reduction (Www.theSTARtrial.Com) (clinicaltrials.gov) - Aug 25, 2017
P3, N=929, Completed, Sponsor: Inspire Medical Systems, Inc.
N=60 --> 78 | Trial primary completion date: Jun 2012 --> Oct 2015 Active, not recruiting --> Completed
- | Enrollment change, Trial withdrawal: Sexual Dysfunction And Hypotestosteronemia In Patients With Obstructive Sleep Apnea Syndrome (clinicaltrials.gov) - Aug 24, 2017
P=N/A, N=0, Withdrawn, Sponsor: Lahey Clinic
Active, not recruiting --> Completed N=200 --> 0 | Active, not recruiting --> Withdrawn
- | Phase classification, Trial primary completion date: The Use of Maternal Serum Unconjugated Estriol for Monitoring the Prevention of Neonatal Respiratory Distress Syndrome (clinicaltrials.gov) - Aug 23, 2017
P=N/A, N=160, Active, not recruiting, Sponsor: Indiana University
N=200 --> 0 | Active, not recruiting --> Withdrawn Phase classification: P4 --> P=N/A | Trial primary completion date: Jul 2017 --> Nov 2016
- | Enrollment change, Trial termination, Trial primary completion date: MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm Infants (clinicaltrials.gov) - Aug 22, 2017
P2, N=4, Terminated, Sponsor: Hamilton Health Sciences Corporation
N=40 --> 4 | Recruiting --> Terminated | Trial primary completion date: Oct 2015 --> Aug 2017; Delay due to infrastructural reasons. Funding withdrawn
- | Phase classification, Trial primary completion date: NIVOLD: Home Non-invasive Ventilation for Chronic Obstructive Pulmonary Disease Patients (clinicaltrials.gov) - Aug 22, 2017
P=N/A, N=12, Terminated, Sponsor: University Hospital, Rouen
Funding withdrawn Phase classification: P2/3 --> P=N/A | Trial primary completion date: Jun 2013 --> Dec 2013
- | Phase classification: Lifestyle Interventions for Seniors With Apnea (clinicaltrials.gov) - Aug 18, 2017
P=N/A, N=18, Completed, Sponsor: Johns Hopkins University
Phase classification: P2/3 --> P=N/A | Trial primary completion date: Jun 2013 --> Dec 2013 Phase classification: P2 --> P=N/A
- | Enrollment closed, Phase classification, Trial primary completion date: Strength Testing After Nitrate Delivery (STAND) in ICU Patients (clinicaltrials.gov) - Aug 15, 2017
P=N/A, N=20, Active, not recruiting, Sponsor: Wake Forest University Health Sciences
Phase classification: P2 --> P=N/A Recruiting --> Active, not recruiting | Phase classification: P1 --> PN/A | Trial primary completion date: Jun 2017 --> Sep 2017
- | Trial completion, Enrollment change: Muscle Ultrasound Signifies Condition Upgrade Leading Approach to Recovery (clinicaltrials.gov) - Aug 15, 2017
P=N/A, N=1, Completed, Sponsor: Wake Forest University Health Sciences
Recruiting --> Active, not recruiting | Phase classification: P1 --> PN/A | Trial primary completion date: Jun 2017 --> Sep 2017 Recruiting --> Completed | N=30 --> 1
- | Trial completion: SUPERNOVA: Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS (clinicaltrials.gov) - Aug 4, 2017
P1/2, N=95, Completed, Sponsor: European Society of Intensive Care Medicine
Recruiting --> Completed | N=30 --> 1 Recruiting --> Completed
- | Trial completion: Pilot Study of the MultiSense Patch to Record Cardiopulmonary Data During Sleep and Wake Cycles (clinicaltrials.gov) - Aug 4, 2017
P=N/A, N=10, Completed, Sponsor: Scripps Translational Science Institute
Recruiting --> Completed Active, not recruiting --> Completed
- | Trial primary completion date: DYSLIM: Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases (clinicaltrials.gov) - Aug 1, 2017
P=N/A, N=199, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Active, not recruiting --> Completed Trial primary completion date: Jan 2015 --> Mar 2014
- | Trial completion: New Data Analysis Methods for Actigraphy in Sleep Medicine (clinicaltrials.gov) - Jul 31, 2017
P=N/A, N=635, Completed, Sponsor: Washington University School of Medicine
Trial primary completion date: Jan 2015 --> Mar 2014 Enrolling by invitation --> Completed
- | Enrollment status: Fluid Shift on Obstructive and Central Sleep Apnea (clinicaltrials.gov) - Jul 28, 2017
P=N/A, N=40, Recruiting, Sponsor: Nanjing Medical University
Enrolling by invitation --> Completed Enrolling by invitation --> Recruiting
- | dexamethasone injection / Generic mfg.
Trial primary completion date: DEXA-ARDS: Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jul 26, 2017
P4, N=314, Recruiting, Sponsor: Dr. Negrin University Hospital
Enrolling by invitation --> Recruiting Trial primary completion date: May 2017 --> Dec 2017
- ||| Trial completion: CATNAP: Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea (clinicaltrials.gov) - Jul 23, 2017
P=N/A, N=281, Completed, Sponsor: University of Pennsylvania
Trial primary completion date: May 2017 --> Dec 2017 Recruiting --> Completed
- | Enrollment change, Trial termination: Neotech RAM Cannula Versus Conventional Binasal Prong Continuous Positive Airway Pressure (CPAP) to Treat Respiratory Distress in Low Birth Weight Neonates (clinicaltrials.gov) - Jul 21, 2017
P=N/A, N=8, Terminated, Sponsor: Children's Hospitals and Clinics of Minnesota
Recruiting --> Completed N=30 --> 8 | Recruiting --> Terminated; Lack of enrollment
- ||| Trial completion, Trial primary completion date: RINO: Impact of Nasal High-flow vs Venturi Mask Oxygen Therapy on Weaning Outcome: a Multicenter, Randomized, Controlled Trial (clinicaltrials.gov) - Jul 21, 2017
P=N/A, N=500, Completed, Sponsor: Catholic University of the Sacred Heart
N=30 --> 8 | Recruiting --> Terminated; Lack of enrollment Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Oct 2016
- | Trial completion, Enrollment change, Trial primary completion date: Prediction of Neonatal Respiratory Distress Syndrome in Preterm Fetuses by Assessment of Fetal Lung Volume by Vocal and Pulmonary Artery Resistance Index a Pilot Study (clinicaltrials.gov) - Jul 18, 2017
P=N/A, N=60, Completed, Sponsor: Ain Shams University
Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Oct 2016 Recruiting --> Completed | N=80 --> 60 | Trial primary completion date: May 2016 --> Mar 2017
- Phase classification, Enrollment change, Trial withdrawal: OVO: Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome (clinicaltrials.gov) - Jul 13, 2017
P=N/A, N=0, Withdrawn, Sponsor: Breas Medical S.A.R.L.
Recruiting --> Completed | N=80 --> 60 | Trial primary completion date: May 2016 --> Mar 2017 Phase classification: P4 --> P=N/A | N=48 --> 0 | Suspended --> Withdrawn
- | Trial termination, Trial primary completion date: CPAP to Reduce Arterial Stiffness in Non Sleepy, Moderate to Severe Obstructive Sleep Apnea (STIFFSLEEP) (clinicaltrials.gov) - Jul 13, 2017
P=N/A, N=45, Terminated, Sponsor: Centro Hospitalar de Lisboa Central
Phase classification: P4 --> P=N/A | N=48 --> 0 | Suspended --> Withdrawn Active, not recruiting --> Terminated | Trial primary completion date: Sep 2016 --> Dec 2016; Recruitment stopped due to time restrains
- | Trial completion, Trial initiation date: Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome (clinicaltrials.gov) - Jul 11, 2017
P4, N=62, Completed, Sponsor: University of Louisville
Active, not recruiting --> Terminated | Trial primary completion date: Sep 2016 --> Dec 2016; Recruitment stopped due to time restrains Active, not recruiting --> Completed | Initiation date: Aug 2005 --> Apr 2004
- | Trial completion: MID-EPIC: Myocardial Ischemia Detection for Early Identification of Patients With Ischemic Chest Pain (clinicaltrials.gov) - Jul 11, 2017
P=N/A, N=50, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | Initiation date: Aug 2005 --> Apr 2004 Active, not recruiting --> Completed
- | Enrollment change, Trial primary completion date: HIFLOWCF: High Flow Nasal Oxygen for Children With Cystic Fibrosis Presenting With Respiratory Failure - a Randomized Controlled Study (clinicaltrials.gov) - Jul 5, 2017
P=N/A, N=4, Terminated, Sponsor: University of Sao Paulo
Active, not recruiting --> Completed N=40 --> 4 | Trial primary completion date: May 2014 --> May 2016
- || Trial primary completion date, Real-world evidence, Real-world: A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD) (clinicaltrials.gov) - Jun 28, 2017
P=N/A, N=700, Recruiting, Sponsor: AstraZeneca
N=40 --> 4 | Trial primary completion date: May 2014 --> May 2016 Trial primary completion date: Mar 2018 --> Aug 2019
- | Phase classification: Patient Comfort During High Flow Nasal Cannula Versus Nasal Continuous Airway Pressure (CPAP) (clinicaltrials.gov) - Jun 26, 2017
P=N/A, N=24, Completed, Sponsor: University Hospital of North Norway
Trial primary completion date: Mar 2018 --> Aug 2019 Phase classification: P3 --> P=N/A
- | Trial completion: A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder (clinicaltrials.gov) - Jun 22, 2017
P=N/A, N=42, Completed, Sponsor: VA Office of Research and Development
Phase classification: P3 --> P=N/A Active, not recruiting --> Completed
- Phase classification: Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) (clinicaltrials.gov) - Jun 19, 2017
P=N/A, N=30, Completed, Sponsor: Fisher and Paykel Healthcare
Active, not recruiting --> Completed Phase classification: P3 --> P=N/A
- | Ventolin (albuterol) / GSK
Trial completion: Nebulae: Effectiveness of Routine Nebulization of Mucolytics and Bronchodilators During Mechanical Ventilation (clinicaltrials.gov) - Jun 16, 2017
P=N/A, N=950, Completed, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phase classification: P3 --> P=N/A Active, not recruiting --> Completed
- | Trial completion: Mus-IRA: Musical Intervention in Non-invasive Ventilation (clinicaltrials.gov) - Jun 15, 2017
P=N/A, N=114, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | furosemide / Generic mfg.
Trial completion, Enrollment change: Aerosol Inhalation Treatment for Dyspnea (clinicaltrials.gov) - Jun 14, 2017
P1/2, N=24, Completed, Sponsor: Beth Israel Deaconess Medical Center
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=15 --> 24
- || GSK1995057 / GSK
Trial primary completion date: Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects. (clinicaltrials.gov) - Jun 12, 2017
P1, N=56, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed | N=15 --> 24 Trial primary completion date: Mar 2012 --> Jun 2012
- | chlorhexidine gluconate / Generic mfg.
Phase classification: P-VAPP: Prehospital Ventilator-Associated Pneumonia Prevention Trial (clinicaltrials.gov) - Jun 9, 2017
P=N/A, N=70, Completed, Sponsor: Nicholas M Mohr
Trial primary completion date: Mar 2012 --> Jun 2012 Phase classification: P2/3 --> P=N/A
- | lorazepam / Generic mfg., midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
Clinical: HYPNOS: How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units (clinicaltrials.gov) - Jun 4, 2017
P1, N=6, Terminated, Sponsor: Vanderbilt University Medical Center
Phase classification: P2/3 --> P=N/A Phase classification: P=N/A --> P1 | N=30 --> 6 | Active, not recruiting --> Terminated; poor recruitment
- || Enrollment closed, Compliance: Efficacy and Compliance of the Mandibular Advancement Devices ONIRIS® vs. Custom Made Devices (clinicaltrials.gov) - Jun 2, 2017
P=N/A, N=204, Active, not recruiting, Sponsor: ONIRIS
Phase classification: P=N/A --> P1 | N=30 --> 6 | Active, not recruiting --> Terminated; poor recruitment Recruiting --> Active, not recruiting
- | Enrollment closed: Pilot Study of the MultiSense Patch to Record Cardiopulmonary Data During Sleep and Wake Cycles (clinicaltrials.gov) - Jun 1, 2017
P=N/A, N=10, Active, not recruiting, Sponsor: Scripps Translational Science Institute
Recruiting --> Active, not recruiting Enrolling by invitation --> Active, not recruiting
- | Enrollment closed, Trial primary completion date, Bariatric surgery: The Effect of Lifestyle Intervention Versus Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects (clinicaltrials.gov) - Jun 1, 2017
P=N/A, N=180, Active, not recruiting, Sponsor: The Hospital of Vestfold
Enrolling by invitation --> Active, not recruiting Completed --> Active, not recruiting | Trial primary completion date: Dec 2009 --> Dec 2025
- | Trial completion, Phase classification, Trial primary completion date: AirconVAP: Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial (clinicaltrials.gov) - May 25, 2017
P=N/A, N=190, Completed, Sponsor: Università degli Studi dell'Insubria
Completed --> Active, not recruiting | Trial primary completion date: Dec 2009 --> Dec 2025 Trial primary completion date: May 2011 --> Mar 2015 | Recruiting --> Completed | Phase classification: P4 --> PN/A
- | midazolam hydrochloride / Generic mfg.
Phase classification, Trial primary completion date: MidPBPK: Midazolam Whole Body Physiologically Based Pharmacokinetic Model (clinicaltrials.gov) - May 25, 2017
P=N/A, N=20, Completed, Sponsor: Università degli Studi dell'Insubria
Trial primary completion date: May 2011 --> Mar 2015 | Recruiting --> Completed | Phase classification: P4 --> PN/A Phase classification: P4 --> P=N/A | Trial primary completion date: Nov 2013 --> May 2014
- | Trial completion: Effects of Combined Cycle Training and Inspiratory Muscle Training in Patients With COPD (clinicaltrials.gov) - May 17, 2017
P=N/A, N=90, Completed, Sponsor: Zhujiang Hospital
Phase classification: P4 --> P=N/A | Trial primary completion date: Nov 2013 --> May 2014 Recruiting --> Completed
- | Phase classification, Enrollment change: Positive Airway Pressure for the Treatment of Asthma (clinicaltrials.gov) - May 17, 2017
P=N/A, N=31, Completed, Sponsor: Brigham and Women's Hospital
Recruiting --> Completed Phase classification: P1/2 --> P=N/A | N=23 --> 31
- | Enrollment change, Trial withdrawal: Effects of Treating Sleep Apnea in Patients With Congestive Heart Failure (clinicaltrials.gov) - May 17, 2017
P=N/A, N=0, Withdrawn, Sponsor: University of Florida
Phase classification: P1/2 --> P=N/A | N=23 --> 31 N=700 --> 0 | Suspended --> Withdrawn
- | Trial completion, Enrollment change: A New Way of Looking at Your Lungs (clinicaltrials.gov) - May 16, 2017
P=N/A, N=86, Completed, Sponsor: University of Oxford
N=700 --> 0 | Suspended --> Withdrawn Recruiting --> Completed | N=125 --> 86
- Trial primary completion date: Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Non-typeable Haemophilus Influenzae (NTHI) Vaccine (clinicaltrials.gov) - May 15, 2017
P1, N=48, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=125 --> 86 Trial primary completion date: Mar 2013 --> Nov 2013
- | Enrollment change, Trial termination, Trial primary completion date: (S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation (clinicaltrials.gov) - May 12, 2017
P4, N=27, Terminated, Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Trial primary completion date: Mar 2013 --> Nov 2013 N=100 --> 27 | Not yet recruiting --> Terminated | Trial primary completion date: Jul 2016 --> Apr 2015; PI resignation
- Enrollment change, Trial withdrawal: Analysis of Impact on Nasal Obstruction by Commercially Available Internal Nasal Stents (clinicaltrials.gov) - May 11, 2017
P=N/A, N=0, Withdrawn, Sponsor: Bethany L. Jones
N=100 --> 27 | Not yet recruiting --> Terminated | Trial primary completion date: Jul 2016 --> Apr 2015; PI resignation N=35 --> 0 | Not yet recruiting --> Withdrawn
- | Trial completion, Phase classification: VICTOR: Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage (clinicaltrials.gov) - May 9, 2017
P=N/A, N=100, Completed, Sponsor: University of Turin, Italy
N=35 --> 0 | Not yet recruiting --> Withdrawn Recruiting --> Completed | Phase classification: P2/3 --> PN/A
- | Enrollment change, Trial termination, Trial primary completion date: Comparative Effects on Diaphragmatic Electrical Activity and Respiratory Pattern of Various Levels of Assistance (clinicaltrials.gov) - May 8, 2017
P=N/A, N=2, Terminated, Sponsor: Prof. Philippe Jolliet
Recruiting --> Completed | Phase classification: P2/3 --> PN/A N=20 --> 2 | Recruiting --> Terminated | Trial primary completion date: Dec 2016 --> Jun 2016; Difficulties to enroll patients
- | Enrollment closed, Trial primary completion date, HEOR, Cost effectiveness: REST: MRA Therapy Versus CPAP Therapy in Moderate OSAS (clinicaltrials.gov) - May 8, 2017
P=N/A, N=86, Active, not recruiting, Sponsor: University Medical Center Groningen
N=20 --> 2 | Recruiting --> Terminated | Trial primary completion date: Dec 2016 --> Jun 2016; Difficulties to enroll patients Recruiting --> Active, not recruiting | Trial primary completion date: May 2017 --> Nov 2017