Recurrence MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	4	8	12	16	20	24	28	32	36	40



CD20 inhib




DNA cross linking agent




VEGFR inhib




Selective progesterone receptor antag




DNA inhib




CD20 inhib




EGFR inhib




VEGF-A inhib




PLK1 inhib




IL-10 stim




Tubulin inhib




IFNα stim




PDGFR β antag




Serotonin 1D receptor agon




TNFα inhib




GnRH agon




c-KIT inhib




µ-opioid agon




Dopamine agon




HER2 inhib




IL-6 inhib




Na+ channel antag




BRAF V600E inhib




COX inhib




Estrogen receptor agon




FGFR3 inhib




IL-1β inhib




Immunosuppressant




TIE-2 inhib




Vascular disrupting agent




mTOR inhib




AKT inhib




CD20 inhib




CTLA4 inhib




Fatty acid inhib




GCR agon




Glutamate receptor antag




HIF-1 inhib




HMG-CoA reductase inhib




Histamine release inhib




IGF-1R inhib




IL-12 inhib




IMPDH inhib




K+ channel antag




Norepinephrine reuptake inhib




Nucleoside guanosine analog




PI3K inhib




β adrenergic receptor antag




AMPA receptor antag




AP-1 inhib



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