|
5 Companies |
|
5 Products |
|
5 Products |
|
4 Mechanisms of Action |
|
0 Trials |
|
65 News |
|
| 12» |
- | NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial completion date, Trial primary completion date: DRIPICCO: Optimal Fluid Management in Adult Severe Malaria (clinicaltrials.gov) - Aug 16, 2018
P=N/A, N=156, Completed, Sponsor: University of Oxford
Recruiting --> Completed | N=120 --> 156 | Trial completion date: Dec 2015 --> Dec 2017 | Trial primary completion date: Dec 2015 --> Dec 2017
- ||| Phase classification, Enrollment change: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Nov 28, 2017
P2, N=61, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=120 --> 156 | Trial completion date: Dec 2015 --> Dec 2017 | Trial primary completion date: Dec 2015 --> Dec 2017 Phase classification: P1 --> P2 | N=32 --> 61
- | Trial completion, Enrollment change: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - May 23, 2017
P1, N=29, Completed, Sponsor: GlaxoSmithKline
Phase classification: P1 --> P2 | N=32 --> 61 Active, not recruiting --> Completed | N=24 --> 29
- Enrollment closed: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Apr 21, 2017
P1, N=24, Active, not recruiting, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed | N=24 --> 29 Recruiting --> Active, not recruiting
- | Trial completion, Enrollment change: Measurements of Doppler Signals Noninvasively From the Lung in Congestive Heart Failure (clinicaltrials.gov) - Feb 8, 2017
P=N/A, N=50, Completed, Sponsor: Echosense Ltd.
Recruiting --> Active, not recruiting Suspended --> Completed | N=150 --> 50
- Trial completion: Electrical Impedance Imaging of Patients on Mechanical Ventilation (clinicaltrials.gov) - Feb 1, 2017
P=N/A, N=2, Completed, Sponsor: Colorado State University
Suspended --> Completed | N=150 --> 50 Recruiting --> Completed
- Trial primary completion date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Jan 23, 2017
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed Trial primary completion date: Oct 2016 --> May 2017
- | Trial completion, Enrollment change: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Jan 23, 2017
P1, N=32, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Oct 2016 --> May 2017 Recruiting --> Completed | N=51 --> 32
- || Trial primary completion date: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Nov 23, 2016
P1, N=51, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=51 --> 32 Trial primary completion date: Sep 2016 --> Dec 2016
- || Trial primary completion date: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Aug 17, 2016
P1, N=51, Recruiting, Sponsor: GlaxoSmithKline
Trial primary completion date: Sep 2016 --> Dec 2016 Trial primary completion date: Jun 2016 --> Sep 2016
- Trial primary completion date: Electrical Impedance Imaging of Patients on Mechanical Ventilation (clinicaltrials.gov) - Jul 28, 2016
P=N/A, N=4, Recruiting, Sponsor: Colorado State University
Trial primary completion date: Jun 2016 --> Sep 2016 Trial primary completion date: Oct 2015 --> Oct 2016
- Trial completion, Enrollment change, Trial primary completion date, Surgery: Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography (clinicaltrials.gov) - Mar 24, 2016
P=N/A, N=130, Completed, Sponsor: Johannes Gutenberg University Mainz
Trial primary completion date: Oct 2015 --> Oct 2016 Recruiting --> Completed | N=80 --> 130 | Trial primary completion date: May 2017 --> Mar 2016
- Trial initiation date, Trial primary completion date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Mar 14, 2016
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed | N=80 --> 130 | Trial primary completion date: May 2017 --> Mar 2016 Initiation date: Sep 2015 --> Jul 2014 | Trial primary completion date: Feb 2016 --> Aug 2016
- sildenafil / Generic mfg.
Trial completion, Enrollment change, Reflex: Prevention and Treatment of Immersion Pulmonary Edema (clinicaltrials.gov) - Jan 26, 2016
P0, N=10, Completed, Sponsor: Duke University
Initiation date: Sep 2015 --> Jul 2014 | Trial primary completion date: Feb 2016 --> Aug 2016 Active, not recruiting --> Completed | N=100 --> 10
- Enrollment open, Trial primary completion date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Jan 26, 2016
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed | N=100 --> 10 Completed --> Recruiting | Trial primary completion date: Oct 2015 --> Feb 2016
- Adempas (riociguat) / Bayer, Merck (MSD)
Trial completion, Enrollment change: Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude (clinicaltrials.gov) - Jan 25, 2016
P4, N=28, Completed, Sponsor: Richard Moon
Completed --> Recruiting | Trial primary completion date: Oct 2015 --> Feb 2016 Active, not recruiting --> Completed | N=20 --> 28
- || Trial primary completion date: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Jan 17, 2016
P1, N=51, Recruiting, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed | N=20 --> 28 Trial primary completion date: Jan 2016 --> Jun 2016
- Trial initiation date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Dec 21, 2015
P1, N=24, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Jan 2016 --> Jun 2016 Initiation date: Jul 2014 --> Sep 2015
- Adempas (riociguat) / Bayer, Merck (MSD)
Enrollment closed, Trial primary completion date: Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude (clinicaltrials.gov) - Dec 10, 2015
P4, N=20, Active, not recruiting, Sponsor: Richard Moon
Initiation date: Jul 2014 --> Sep 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2015 --> Dec 2015
- | Trial completion: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Oct 19, 2015
P1, N=24, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2015 --> Dec 2015 Recruiting --> Completed
- Trial primary completion date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Sep 24, 2015
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed Trial primary completion date: Jul 2015 --> Oct 2015
- Trial completion, Enrollment change: 09-045: Role of Sphingolipids in Pulmonary Edema (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=45, Completed, Sponsor: RWTH Aachen University
Trial primary completion date: Jul 2015 --> Oct 2015 Recruiting --> Completed | N=70 --> 45
- Enrollment change, Trial withdrawal: Safety Study of Inhaled Saline in Acute Lung Injury (clinicaltrials.gov) - Aug 17, 2015
P1, N=0, Withdrawn, Sponsor: Mayo Clinic
Recruiting --> Completed | N=70 --> 45 N=15 --> 0 | Recruiting --> Withdrawn
- Enrollment open: Electrical Impedance Imaging of Patients on Mechanical Ventilation (clinicaltrials.gov) - Aug 6, 2015
P=N/A, N=4, Recruiting, Sponsor: Colorado State University
N=15 --> 0 | Recruiting --> Withdrawn Not yet recruiting --> Recruiting
- Trial primary completion date: Measurements of Doppler Signals Noninvasively From the Lung in Congestive Heart Failure (clinicaltrials.gov) - Jul 15, 2015
P=N/A, N=150, Suspended, Sponsor: Echosense Ltd.
Not yet recruiting --> Recruiting Trial primary completion date: Mar 2015 --> Dec 2015
- Trial primary completion date: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Apr 19, 2015
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Trial primary completion date: Mar 2015 --> Dec 2015 Trial primary completion date: Oct 2014 --> Jul 2015
- | Trial suspension: Measurements of Doppler Signals Noninvasively From the Lung in Congestive Heart Failure (clinicaltrials.gov) - Jan 18, 2015
P=N/A, N=150, Suspended, Sponsor: Echosense Ltd.
Trial primary completion date: Oct 2014 --> Jul 2015 Recruiting --> Suspended
- Surgery: Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=80, Recruiting, Sponsor: Johannes Gutenberg University Mainz
- Trial initiation date, Trial primary completion date: Safety Study of Inhaled Saline in Acute Lung Injury (clinicaltrials.gov) - Dec 17, 2014
P1, N=15, Recruiting, Sponsor: Mayo Clinic
Recruiting --> Suspended Initiation date: Oct 2012 --> Oct 2013 | Trial primary completion date: Jun 2014 --> Jun 2015
- Adempas (riociguat) / Bayer, Merck (MSD)
Enrollment open, Trial primary completion date: Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude (clinicaltrials.gov) - Dec 10, 2014
P4, N=20, Recruiting, Sponsor: Richard Moon
Initiation date: Oct 2012 --> Oct 2013 | Trial primary completion date: Jun 2014 --> Jun 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Sep 2015
- || Enrollment change: VitalCare: The Prevention of Failure to Rescue Using Early Warning Scoring (clinicaltrials.gov) - Nov 20, 2014
P=N/A, N=414, Completed, Sponsor: Philips Healthcare
Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Sep 2015 N=100 --> 414
- || sildenafil / Generic mfg.
Enrollment closed, Trial primary completion date, Reflex: Prevention and Treatment of Immersion Pulmonary Edema (clinicaltrials.gov) - Nov 17, 2014
P0, N=100, Active, not recruiting, Sponsor: Duke University
N=100 --> 414 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Dec 2015
- Clinical: Electrical Impedance Imaging of Patients on Mechanical Ventilation (clinicaltrials.gov) - Sep 5, 2014
P=N/A, N=4, Not yet recruiting, Sponsor: Colorado State University
- Enrollment open: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - Aug 27, 2014
P1, N=24, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Dec 2015 Not yet recruiting --> Recruiting
- ||| Enrollment open: Measurements of Doppler Signals Noninvasively From the Lung in Congestive Heart Failure (clinicaltrials.gov) - Jun 26, 2014
P=N/A, N=150, Recruiting, Sponsor: Echosense Ltd.
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||| Enrollment open: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Jun 17, 2014
P1, N=51, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Phase classification: Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure (clinicaltrials.gov) - Jun 12, 2014
P1, N=20, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Phase classification: P=N/A --> P1
- || Trial primary completion date: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Jun 4, 2014
P1, N=51, Not yet recruiting, Sponsor: GlaxoSmithKline
Phase classification: P=N/A --> P1 Trial primary completion date: Jan 2015 --> Apr 2015
- | New P1 trial: A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure (clinicaltrials.gov) - May 8, 2014
P1, N=24, Not yet recruiting, Sponsor: GlaxoSmithKline
- ||| New P1 trial: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients (clinicaltrials.gov) - Apr 17, 2014
P1, N=51, Not yet recruiting, Sponsor: GlaxoSmithKline
- Trial completion: Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study) (clinicaltrials.gov) - Apr 1, 2014
P=N/A, N=104000, Completed, Sponsor: Massachusetts General Hospital
Trial primary completion date: Jan 2015 --> Apr 2015 Not yet recruiting --> Completed
- Trial completion: The Effect of 10 cm Catheter Mount on Malfunction of Capnometers Under the Conditions of Water (clinicaltrials.gov) - Mar 15, 2014
P=N/A, N=25, Completed, Sponsor: Hanyang University
Not yet recruiting --> Completed Recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure (clinicaltrials.gov) - Feb 22, 2014
P2, N=20, Completed, Sponsor: Synvista Therapeutics, Inc
Recruiting --> Completed No longer recruiting --> Completed
- Adempas (riociguat) / Bayer, Merck (MSD)
New P4 trial: Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude (clinicaltrials.gov) - Dec 29, 2013
P4, N=20, Not yet recruiting, Sponsor: Richard Moon
- Trial termination: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
No longer recruiting --> Completed Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates.
- Enrollment change: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates. N=50 --> 23
- Natrecor (nesiritide) / J&J
Trial withdrawal: Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF (clinicaltrials.gov) - Sep 19, 2013
P4, N=0, Withdrawn, Sponsor: University of Medicine and Dentistry New Jersey
N=50 --> 23 Not yet recruiting --> Withdrawn
- Natrecor (nesiritide) / J&J
Enrollment change: Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF (clinicaltrials.gov) - Sep 19, 2013
P4, N=0, Withdrawn, Sponsor: University of Medicine and Dentistry New Jersey
Not yet recruiting --> Withdrawn N=46 --> 0
- Trial completion: Susceptibility to High Altitude Pulmonary Edema in Subjects With Increased Hypoxic Pulmonary Vasoconstriction (clinicaltrials.gov) - Sep 4, 2013
P=N/A, N=30, Completed, Sponsor: University of Heidelberg
N=46 --> 0 Recruiting --> Completed
- furosemide / Generic mfg.
Trial withdrawal: Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload (clinicaltrials.gov) - Apr 3, 2013
P=N/A, N=0, Withdrawn, Sponsor: M.D. Anderson Cancer Center
Recruiting --> Completed Not yet recruiting --> Withdrawn