Psoriasis MOAs - LARVOL Sigma

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Psoriasis

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Phase N/A 1 2 3 4 Products	0	4	8	12	16	20	24	28	32	36	40



CD20 inhib




IL-22 inhib




FLT3 inhib




CD40 inhib




GCR agon




IL-23 inhib




TNFα inhib




JAK2 inhib




Calcitriol receptor agon




Retinoic acid receptor agon




Steroid receptor agon




THF dehydrogenase inhib




Calcineurin inhib




IL-17A inhib




Immunosuppressant




PDE4 inhib




CD40 inhib




IFNγ inhib




T-cell activation inhib




BRAF inhib




IL-12 inhib




NF-κB inhib




TLR2 antag




Bcl2 inhib




Bcl2 inhib




CD40 inhib




CXCR1 antag




Dihydrofolic acid reductase inhib




FGFR3 inhib




GLP-1 receptor agon




IMPDH inhib




NF E2 related factor 2 stim




PDGFR β antag




Tubulin polymerization promoter




Undefined mechanism




c-KIT inhib




α4β1 integrin antag




AHR mod




Acetylcholine inhib




Adenosine A3 receptor agon




Apoptosis stim




Autophagy inhib




BRAF inhib




Bone morphogenetic protein receptor type II mod




CD11a antag




CD20 inhib




CYP24 inhib




Calcitonin receptor agon




Caspase 1 inhib




Cathepsin S inhib



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