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41 Companies |
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29 Products |
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29 Products |
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22 Mechanisms of Action |
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2 Trials |
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854 News |
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- | Enrollment closed: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC (clinicaltrials.gov) - May 25, 2014
P3, N=500, Active, not recruiting, Sponsor: Institute of Tropical Medicine, Belgium
Recruiting --> Active, not recruiting
- Lampit (nifurtimox) / Bayer
Trial primary completion date: Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' Patients (clinicaltrials.gov) - May 18, 2014
P1, N=36, Recruiting, Sponsor: Bayer
Recruiting --> Active, not recruiting Trial primary completion date: May 2014 --> Jul 2014
- artemether/lumefantrine / Generic mfg.
Trial primary completion date: Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy (clinicaltrials.gov) - May 15, 2014
P4, N=19, Terminated, Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Trial primary completion date: May 2014 --> Jul 2014 Trial primary completion date: Dec 2014 --> Mar 2014
- artemether/lumefantrine / Generic mfg.
Trial termination: Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy (clinicaltrials.gov) - May 15, 2014
P4, N=19, Terminated, Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Trial primary completion date: Dec 2014 --> Mar 2014 Recruiting --> Terminated; Slow accrual and funding limitations.
- artemether/lumefantrine / Generic mfg.
Trial completion date: Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy (clinicaltrials.gov) - May 15, 2014
P4, N=19, Terminated, Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Recruiting --> Terminated; Slow accrual and funding limitations. Trial completion date: Feb 2015 --> Mar 2014
- artemether/lumefantrine / Generic mfg.
Enrollment change: Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy (clinicaltrials.gov) - May 15, 2014
P4, N=19, Terminated, Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Trial completion date: Feb 2015 --> Mar 2014 N=48 --> 19
- chloroquine phosphate / Generic mfg.
Trial initiation date: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis (clinicaltrials.gov) - May 13, 2014
P1, N=30, Completed, Sponsor: Sanaria Inc.
N=48 --> 19 Initiation date: Oct 2012 --> Sep 2012
- chloroquine phosphate / Generic mfg.
Trial completion date: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis (clinicaltrials.gov) - May 13, 2014
P1, N=30, Completed, Sponsor: Sanaria Inc.
Initiation date: Oct 2012 --> Sep 2012 Trial completion date: Mar 2014 --> Feb 2014
- | chloroquine phosphate / Generic mfg.
Trial completion: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis (clinicaltrials.gov) - May 13, 2014
P1, N=30, Completed, Sponsor: Sanaria Inc.
Trial completion date: Mar 2014 --> Feb 2014 Active, not recruiting --> Completed
- Trial primary completion date: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) (clinicaltrials.gov) - May 12, 2014
P=N/A, N=2170, Recruiting, Sponsor: University Hospital, Geneva
Active, not recruiting --> Completed Trial primary completion date: Feb 2014 --> Dec 2014
- Trial completion date: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) (clinicaltrials.gov) - May 12, 2014
P=N/A, N=2170, Recruiting, Sponsor: University Hospital, Geneva
Trial primary completion date: Feb 2014 --> Dec 2014 Trial completion date: May 2014 --> Dec 2014
- Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Trial primary completion date: STOP MiP KENYA: Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya (clinicaltrials.gov) - May 5, 2014
P4, N=1554, Active, not recruiting, Sponsor: Kenya Medical Research Institute
Trial completion date: May 2014 --> Dec 2014 Trial primary completion date: Mar 2014 --> Oct 2014
- Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Trial completion date: STOP MiP KENYA: Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya (clinicaltrials.gov) - May 5, 2014
P4, N=1554, Active, not recruiting, Sponsor: Kenya Medical Research Institute
Trial primary completion date: Mar 2014 --> Oct 2014 Trial completion date: Jun 2014 --> Jun 2015
- Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi, Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi, Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Trial completion date: PREGACT: Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria (clinicaltrials.gov) - May 5, 2014
P3, N=3480, Active, not recruiting, Sponsor: Institute of Tropical Medicine, Belgium
Trial completion date: Jun 2014 --> Jun 2015 Trial completion date: Jul 2014 --> Feb 2015
- ||| PfSPZ Vaccine / Sanaria
New P1 trial: Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults (clinicaltrials.gov) - May 5, 2014
P1, N=73, Recruiting, Sponsor: Sanaria Inc.
- Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Enrollment closed: STOP MiP KENYA: Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya (clinicaltrials.gov) - May 5, 2014
P4, N=1554, Active, not recruiting, Sponsor: Kenya Medical Research Institute
Trial completion date: Jul 2014 --> Feb 2015 Recruiting --> Active, not recruiting
- trimethoprim/sulfamethoxazole / Generic mfg., sulfadoxine/pyrimethamine / Generic mfg.
Trial primary completion date: PROMOTE-Chemop: Chemopreventive Therapy for Malaria in Ugandan Children (clinicaltrials.gov) - Apr 29, 2014
P3, N=600, Completed, Sponsor: University of California, San Francisco
Recruiting --> Active, not recruiting Trial primary completion date: Jul 2014 --> Apr 2014
- trimethoprim/sulfamethoxazole / Generic mfg., sulfadoxine/pyrimethamine / Generic mfg.
Trial completion date: PROMOTE-Chemop: Chemopreventive Therapy for Malaria in Ugandan Children (clinicaltrials.gov) - Apr 29, 2014
P3, N=600, Completed, Sponsor: University of California, San Francisco
Trial primary completion date: Jul 2014 --> Apr 2014 Trial completion date: Jul 2014 --> Apr 2014
- | trimethoprim/sulfamethoxazole / Generic mfg., sulfadoxine/pyrimethamine / Generic mfg.
Trial completion: PROMOTE-Chemop: Chemopreventive Therapy for Malaria in Ugandan Children (clinicaltrials.gov) - Apr 29, 2014
P3, N=600, Completed, Sponsor: University of California, San Francisco
Trial completion date: Jul 2014 --> Apr 2014 Active, not recruiting --> Completed
- Mosquirix (RTS,S) / GSK
Enrollment open: A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S (clinicaltrials.gov) - Apr 28, 2014
P1/2, N=46, Recruiting, Sponsor: University of Oxford
Active, not recruiting --> Completed Active, not recruiting --> Recruiting
- Trial initiation date: Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib (clinicaltrials.gov) - Apr 24, 2014
P1, N=56, Recruiting, Sponsor: Centre Hospitalier Universitaire Vaudois
Active, not recruiting --> Recruiting Initiation date: Oct 2013 --> Mar 2014
- Enrollment open: Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP) (clinicaltrials.gov) - Apr 24, 2014
P1, N=27, Recruiting, Sponsor: Medicines for Malaria Venture
Initiation date: Oct 2013 --> Mar 2014 Not yet recruiting --> Recruiting
- Enrollment open: Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib (clinicaltrials.gov) - Apr 24, 2014
P1, N=56, Recruiting, Sponsor: Centre Hospitalier Universitaire Vaudois
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||| Trial completion: Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT) (clinicaltrials.gov) - Apr 20, 2014
P=N/A, N=1893, Completed, Sponsor: Fyodor Biotechnologies Inc
Not yet recruiting --> Recruiting Recruiting --> Completed
- | chloroquine phosphate / Generic mfg.
New P4 trial: CRePViCam: Assessment of Plasmodium Vivax Chloroquine Resistance in Cambodia: (clinicaltrials.gov) - Apr 17, 2014
P4, N=100, Not yet recruiting, Sponsor: Institut Pasteur, Cambodia
- | DSM265 / Medicines for Malaria Venture
New P2a trial: DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax (clinicaltrials.gov) - Apr 14, 2014
P2a, N=60, Not yet recruiting, Sponsor: Medicines for Malaria Venture
- ||| New P1 trial: Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis (clinicaltrials.gov) - Apr 14, 2014
P1, N=58, Recruiting, Sponsor: Sanaria Inc.
- Enrollment open: Auranofin PK Following Oral Dose Administration (clinicaltrials.gov) - Apr 9, 2014
P1, N=15, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Not yet recruiting --> Recruiting
- sulfadoxine/pyrimethamine / Generic mfg.
Trial completion: IPTp_IST: Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy (clinicaltrials.gov) - Apr 9, 2014
P4, N=5354, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Not yet recruiting --> Recruiting Recruiting --> Completed
- ||||| Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
New P2 trial: Eurartesim (clinicaltrials.gov) - Apr 8, 2014
P2, N=100, Not yet recruiting, Sponsor: sigma-tau i.f.r. S.p.A.
- trimethoprim/sulfamethoxazole / Generic mfg.
Trial completion: Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya (clinicaltrials.gov) - Apr 8, 2014
P=N/A, N=500, Completed, Sponsor: University of Washington
Recruiting --> Completed Recruiting --> Completed
- Fluarix (influenza virus trivalent vaccine) / GSK
Trial withdrawal: Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya (clinicaltrials.gov) - Apr 7, 2014
P2/3, N=0, Withdrawn, Sponsor: Centers for Disease Control and Prevention
Recruiting --> Completed Not yet recruiting --> Withdrawn
- Fluarix (influenza virus trivalent vaccine) / GSK
Trial initiation date: Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya (clinicaltrials.gov) - Apr 7, 2014
P2/3, N=0, Withdrawn, Sponsor: Centers for Disease Control and Prevention
Not yet recruiting --> Withdrawn Initiation date: Jan 2014 --> Apr 2014
- Fluarix (influenza virus trivalent vaccine) / GSK
Enrollment change: Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya (clinicaltrials.gov) - Apr 7, 2014
P2/3, N=0, Withdrawn, Sponsor: Centers for Disease Control and Prevention
Initiation date: Jan 2014 --> Apr 2014 N=720 --> 0
- | gentamicin sulfate / Generic mfg.
Enrollment open: Phase 3 Study of Walter Reed (WR) 279,396 and Paromomycin Alone for the Treatment of Cutaneous Leishmaniasis in Panama (clinicaltrials.gov) - Apr 7, 2014
P3, N=300, Recruiting, Sponsor: U.S. Army Medical Research and Materiel Command
N=720 --> 0 Suspended --> Recruiting
- Clinical: NIDIAGDigest: Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (clinicaltrials.gov) - Apr 3, 2014
P=N/A, N=4000, Not yet recruiting, Sponsor: Swiss Tropical & Public Health Institute
- Enrollment open: Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers (clinicaltrials.gov) - Apr 1, 2014
P1, N=36, Recruiting, Sponsor: Infectious Disease Research Institute
Suspended --> Recruiting Not yet recruiting --> Recruiting
- | artemether/lumefantrine / Generic mfg.
Trial completion: Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy (clinicaltrials.gov) - Mar 23, 2014
P3, N=96, Completed, Sponsor: University of Oxford
Not yet recruiting --> Recruiting Recruiting --> Completed
- trimethoprim/sulfamethoxazole / Generic mfg.
New P1 trial: Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in Uganda (clinicaltrials.gov) - Mar 19, 2014
P1, N=400, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi
Trial completion: Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease (clinicaltrials.gov) - Mar 19, 2014
P1/2, N=270, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Recruiting --> Completed Active, not recruiting --> Completed
- | New P4 trial: DHART: Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria (clinicaltrials.gov) - Mar 18, 2014
P4, N=216, Not yet recruiting, Sponsor: University of Oxford
- mefloquine / Generic mfg.
Trial completion: MiPPAD: Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy (clinicaltrials.gov) - Mar 18, 2014
P=N/A, N=5820, Completed, Sponsor: Hospital Clinic of Barcelona
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, Head-to-Head: PALUFER: Long-term Iron Supplements and Malaria Risk in Early Pregnancy: a Randomized Controlled Trial (clinicaltrials.gov) - Mar 17, 2014
P=N/A, N=1959, Completed, Sponsor: Liverpool School of Tropical Medicine
Active, not recruiting --> Completed Recruiting --> Completed
- | artemether/lumefantrine / Generic mfg.
New P4 trial: Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria. (clinicaltrials.gov) - Mar 16, 2014
P4, N=140, Completed, Sponsor: Richard Mwaiswelo
- New P1 trial: Auranofin PK Following Oral Dose Administration (clinicaltrials.gov) - Mar 13, 2014
P1, N=15, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- | pentoxifylline / Generic mfg.
Enrollment open, IO biomarker, Immunomodulating: Add-on Study of Pentoxifylline in Cutaneous Leishmaniasis (clinicaltrials.gov) - Mar 10, 2014
P2/3, N=100, Recruiting, Sponsor: Centro Internacional de Entrenamiento e Investigaciones M
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: Pharmacokinetics of Miltefosine in Children and Adults (clinicaltrials.gov) - Mar 10, 2014
P4, N=60, Recruiting, Sponsor: Centro Internacional de Entrenamiento e Investigaciones M
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | New P2b trial: Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria. (clinicaltrials.gov) - Mar 9, 2014
P2b, N=495, Not yet recruiting, Sponsor: Medicines for Malaria Venture
- New P2 trial: Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax (clinicaltrials.gov) - Mar 9, 2014
P2, N=32, Not yet recruiting, Sponsor: Malaria Vaccine and Drug Development Center
- New P1 trial: A Phase I Study to Assess the Safety and Immunogenicity of ChAd63 ME-TRAP - MVA ME-TRAP Heterologous Prime-boost Vaccination Co-administered With EPI Vaccines in Gambian Infants (clinicaltrials.gov) - Mar 9, 2014
P1, N=65, Active, not recruiting, Sponsor: University of Oxford