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41 Companies |
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29 Products |
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29 Products |
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22 Mechanisms of Action |
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2 Trials |
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854 News |
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- ||||| Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi
Trial initiation date: Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria (clinicaltrials.gov) - Jan 10, 2012
P3, N=380, Completed, Sponsor: Sanofi
Initiation date: Oct 2011 --> Jan 2012
- | Trial completion: Phase 3 Study to Evaluate WR 279,396 vs. Paromomycin Alone to Treat Cutaneous Leishmaniasis (in Tunisia) (clinicaltrials.gov) - Jan 4, 2012
P3, N=375, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Initiation date: Oct 2011 --> Jan 2012 Active, not recruiting --> Completed
- chloroquine phosphate / Generic mfg., primaquine / Generic mfg.
New P1 trial: Malaria Challenge in Healthy Volunteers (clinicaltrials.gov) - Dec 27, 2011
P1, N=36, Completed, Sponsor: Seattle Biomedical Research Institute
- gentamicin sulfate / Generic mfg.
New P2 trial: WR 279,396 Open Label Treatment Protocol in Tunisia (clinicaltrials.gov) - Dec 15, 2011
P2, N=120, Suspended, Sponsor: U.S. Army Medical Research and Materiel Command
- Trial initiation date: Time to Become Negative of Three Rapid Diagnostic Tests for Malaria (clinicaltrials.gov) - Dec 7, 2011
P=N/A, N=424, Recruiting, Sponsor: Epicentre
Active, not recruiting --> Completed Initiation date: Apr 2011 --> Sep 2011
- Enrollment open: Time to Become Negative of Three Rapid Diagnostic Tests for Malaria (clinicaltrials.gov) - Dec 7, 2011
P=N/A, N=424, Recruiting, Sponsor: Epicentre
Initiation date: Apr 2011 --> Sep 2011 Not yet recruiting --> Recruiting
- New P1 trial: Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteers (clinicaltrials.gov) - Nov 30, 2011
P1, N=36, Completed, Sponsor: Infectious Disease Research Institute
- gentamicin sulfate / Generic mfg.
Trial completion: Safety, Efficacy and Pharmacokinetics (PK) Study of WR 279,396 Versus Paromomycin for Treatment of Cutaneous Leishmaniasis (Peru-PK) (clinicaltrials.gov) - Nov 29, 2011
P2, N=30, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Fexinidazole Winthrop (fexinidazole) / Sanofi
New P1 trial: Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With Food (clinicaltrials.gov) - Nov 28, 2011
P1, N=30, Terminated, Sponsor: Drugs for Neglected Diseases
- New P1 trial: Antiretroviral Drug Interaction Study in Volunteers With HIV (clinicaltrials.gov) - Nov 22, 2011
P1, N=32, Completed, Sponsor: National Institutes of Health Clinical Center (CC)
- Enrollment change: RDTACT: Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar (clinicaltrials.gov) - Nov 13, 2011
P=N/A, N=3890, Completed, Sponsor: Karolinska University Hospital
Active, not recruiting --> Completed N=5000 --> 3890
- Trial completion: RDTACT: Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar (clinicaltrials.gov) - Nov 13, 2011
P=N/A, N=3890, Completed, Sponsor: Karolinska University Hospital
N=5000 --> 3890 Not yet recruiting --> Completed
- || pentoxifylline / Generic mfg.
New P2/3 trial, IO biomarker, Immunomodulating: Add-on Study of Pentoxifylline in Cutaneous Leishmaniasis (clinicaltrials.gov) - Nov 1, 2011
P2/3, N=100, Recruiting, Sponsor: Centro Internacional de Entrenamiento e Investigaciones M
- gentamicin sulfate / Generic mfg.
Trial completion: Pharmacokinetics, Safety, and Efficacy Trial of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream for the Treatment of Cutaneous Leishmaniasis in Panama (clinicaltrials.gov) - Oct 25, 2011
P2, N=30, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Not yet recruiting --> Completed Active, not recruiting --> Completed
- sulfadoxine/pyrimethamine / Generic mfg.
Trial completion: Age of Exposure and Immunity to Malaria in Infants (clinicaltrials.gov) - Oct 25, 2011
P=N/A, N=349, Completed, Sponsor: Hospital Clinic of Barcelona
Active, not recruiting --> Completed Recruiting --> Completed
- | New P4 trial: Pharmacokinetics of Miltefosine in Children and Adults (clinicaltrials.gov) - Oct 24, 2011
P4, N=60, Recruiting, Sponsor: Centro Internacional de Entrenamiento e Investigaciones M
- Trial completion: Outcomes of an Anticoagulation Clinic in an University Hospital (clinicaltrials.gov) - Oct 23, 2011
P4, N=280, Completed, Sponsor: Federal University of Minas Gerais
Recruiting --> Completed Active, not recruiting --> Completed
- || New P3 trial: Insecticide Treated Polyethylene Sheeting for Prevention of Malaria in Emergencies (clinicaltrials.gov) - Oct 18, 2011
P3, N=222, Completed, Sponsor: The Mentor Initiative
- Enrollment open: Bihar Evaluation of Social Franchising and Telemedicine (clinicaltrials.gov) - Oct 13, 2011
P=N/A, N=106380, Enrolling by invitation, Sponsor: Duke University
Active, not recruiting --> Completed Not yet recruiting --> Enrolling by invitation
- New P1 trial: AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area (clinicaltrials.gov) - Oct 10, 2011
P1, N=72, Completed, Sponsor: University of Oxford
- New P1 trial: Safety and Immunogenicity of New Malaria Vaccine Candidate ChAd63 CS Administered Alone and With MVA CS (clinicaltrials.gov) - Oct 10, 2011
P1, N=24, Completed, Sponsor: University of Oxford
- || trimethoprim/sulfamethoxazole / Generic mfg.
New P3 trial: ISROT: Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis (clinicaltrials.gov) - Oct 6, 2011
P3, N=140, Recruiting, Sponsor: University of Campinas, Brazil
- Enrollment change: Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia (clinicaltrials.gov) - Oct 5, 2011
P=N/A, N=415, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Enrolling by invitation N=300 --> 415
- New P2 trial: Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria (clinicaltrials.gov) - Oct 2, 2011
P2, N=20, Terminated, Sponsor: Sanofi
- Trial completion: A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP (clinicaltrials.gov) - Oct 2, 2011
P1, N=54, Completed, Sponsor: University of Oxford
N=300 --> 415 Active, not recruiting --> Completed
- || chloroquine phosphate / Generic mfg.
New P3 trial: Chloroquine for Malaria in Pregnancy (clinicaltrials.gov) - Sep 27, 2011
P3, N=900, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- ||||| sevuparin (DF-02) / Modus Therap, Mahidol Oxford Tropical Medicine Research Unit
New P1/2 trial: Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malaria (clinicaltrials.gov) - Sep 26, 2011
P1/2, N=95, Recruiting, Sponsor: Dilaforette AB
- clindamycin phosphate / Generic mfg.
Trial withdrawal: JP015: Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate (clinicaltrials.gov) - Sep 25, 2011
P2, N=40, Withdrawn, Sponsor: Jomaa Pharma GmbH
Active, not recruiting --> Completed Not yet recruiting --> Withdrawn
- PfSPZ Vaccine / Sanaria
New P1 trial: Experimental PfSPZ Vaccine in Adults Without Malaria (clinicaltrials.gov) - Sep 25, 2011
P1, N=64, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- | New P2 trial: Safer Sex Program for Young African-American Men (clinicaltrials.gov) - Sep 21, 2011
P2, N=620, Recruiting, Sponsor: University of Kentucky
- amphotericin b liposome / Generic mfg.
New P1/2 trial, Combination therapy: SCH708980 With and Without AmBisome for Visceral Leishmaniasis (clinicaltrials.gov) - Sep 18, 2011
P1/2, N=0, Withdrawn, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- amodiaquine hydrochloride / Generic mfg., sulfadoxine/pyrimethamine / Generic mfg.
Trial completion: Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc) (clinicaltrials.gov) - Sep 15, 2011
P1/2, N=150, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Not yet recruiting --> Withdrawn Not yet recruiting --> Completed
- Trial completion: Phase II Artesunate Study in Severe Malaria (clinicaltrials.gov) - Sep 14, 2011
P2, N=200, Completed, Sponsor: Medicines for Malaria Venture
Not yet recruiting --> Completed Active, not recruiting --> Completed
- Trial completion: Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam (clinicaltrials.gov) - Sep 13, 2011
P2, N=166, Completed, Sponsor: Oxford University Clinical Research Unit, Vietnam
Active, not recruiting --> Completed Recruiting --> Completed
- New P1 trial: Initial Study of Malaria Vaccine Pfs25-EPA/Alhydrogel(Registered Trademark) (clinicaltrials.gov) - Sep 12, 2011
P1, N=30, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- || artemether/lumefantrine / Generic mfg.
New P3 trial: Trial of Malaria Seasonal IPTc Combined With Community Case Management (clinicaltrials.gov) - Sep 10, 2011
P3, N=4554, Completed, Sponsor: Cheikh Anta Diop University, Senegal
- Inomax (nitric oxide) / Mallinckrodt
Enrollment open: Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children (clinicaltrials.gov) - Sep 7, 2011
P2, N=92, Recruiting, Sponsor: Epicentre
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment change: Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs (clinicaltrials.gov) - Aug 11, 2011
P=N/A, N=6456, Completed, Sponsor: Mbarara University of Science and Technology
Not yet recruiting --> Recruiting N=1050 --> 6456
- Enrollment change: Malaria Survey in Mbarara District, Uganda 2010 (clinicaltrials.gov) - Aug 10, 2011
P=N/A, N=2320, Completed, Sponsor: Epicentre
N=1050 --> 6456 N=1320 --> 2320
- Trial completion: Malaria Survey in Mbarara District, Uganda 2010 (clinicaltrials.gov) - Aug 10, 2011
P=N/A, N=2320, Completed, Sponsor: Epicentre
N=1320 --> 2320 Recruiting --> Completed
- Enrollment open: Tracking Resistance to Artemisinin (TRAC) (clinicaltrials.gov) - Aug 8, 2011
P4, N=1800, Recruiting, Sponsor: University of Oxford
Recruiting --> Completed Not yet recruiting --> Recruiting