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41 Companies |
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29 Products |
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29 Products |
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22 Mechanisms of Action |
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2 Trials |
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854 News |
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- Trial completion: The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands (clinicaltrials.gov) - Sep 3, 2013
P=N/A, N=1477, Completed, Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
Recruiting --> Completed
- Enrollment closed: Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART (clinicaltrials.gov) - Sep 2, 2013
P0, N=140, Active, not recruiting, Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Recruiting --> Completed Recruiting --> Active, not recruiting
- | primaquine / Generic mfg.
Trial completion: ACTPQ: Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria (clinicaltrials.gov) - Aug 27, 2013
P3, N=331, Completed, Sponsor: University of Oxford
Recruiting --> Active, not recruiting Recruiting --> Completed
- | chloroquine phosphate / Generic mfg., primaquine / Generic mfg.
Trial completion: Study on the Treatment of Vivax Malaria (clinicaltrials.gov) - Aug 26, 2013
P3, N=655, Completed, Sponsor: University of Oxford
Recruiting --> Completed Recruiting --> Completed
- amphotericin b liposome / Generic mfg.
Trial withdrawal, Combination therapy: SCH708980 With and Without AmBisome for Visceral Leishmaniasis (clinicaltrials.gov) - Aug 25, 2013
P1/2, N=0, Withdrawn, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Not yet recruiting --> Withdrawn
- amphotericin b liposome / Generic mfg.
Enrollment change, Combination therapy: SCH708980 With and Without AmBisome for Visceral Leishmaniasis (clinicaltrials.gov) - Aug 25, 2013
P1/2, N=0, Withdrawn, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Withdrawn N=90 --> 0
- | Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Enrollment open: PRINOGAM: Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers (clinicaltrials.gov) - Aug 23, 2013
P3, N=1200, Recruiting, Sponsor: Medical Research Council Unit, The Gambia
N=90 --> 0 Not yet recruiting --> Recruiting
- ||| Trial completion: Tafenoquine Thorough QTc Study in Healthy Subjects (clinicaltrials.gov) - Aug 21, 2013
P1, N=260, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- azithromycin / Generic mfg.
Trial completion, Combination therapy: Azithromycin Combination Therapy for the Treatment of Severe Malaria (clinicaltrials.gov) - Aug 21, 2013
P2, N=75, Completed, Sponsor: Medical University of Vienna
Not yet recruiting --> Completed Not yet recruiting --> Completed
- quinine/doxycycline / Generic mfg.
Trial completion: Artemisinin Resistance in Bangladesh (clinicaltrials.gov) - Aug 21, 2013
P=N/A, N=126, Completed, Sponsor: Medical University of Vienna
Not yet recruiting --> Completed Recruiting --> Completed
- | Lampit (nifurtimox) / Bayer
New P1 trial: Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' Patients (clinicaltrials.gov) - Aug 20, 2013
P1, N=36, Recruiting, Sponsor: Bayer
- | Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
New P4 trial: Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO (clinicaltrials.gov) - Aug 8, 2013
P4, N=60, Not yet recruiting, Sponsor: Ifakara Health Institute
- Trial initiation date: Safer Sex Program for Young African-American Men (clinicaltrials.gov) - Aug 7, 2013
P2, N=620, Recruiting, Sponsor: University of Kentucky
Recruiting --> Completed Initiation date: Jun 2012 --> Sep 2012
- Enrollment open: Safer Sex Program for Young African-American Men (clinicaltrials.gov) - Aug 7, 2013
P2, N=620, Recruiting, Sponsor: University of Kentucky
Initiation date: Jun 2012 --> Sep 2012 Not yet recruiting --> Recruiting
- || artemether/lumefantrine / Generic mfg.
New P3 trial: Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy (clinicaltrials.gov) - Aug 4, 2013
P3, N=96, Completed, Sponsor: University of Oxford
- Trial completion: Safety and Immunogenicity of Novel Vaccination Schedules With Malaria Vaccines AdCh63 ME-TRAP and MVA ME-TRAP (clinicaltrials.gov) - Jul 25, 2013
P1, N=39, Completed, Sponsor: University of Oxford
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | New P4 trial: GhanaCommRDT: The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level (clinicaltrials.gov) - Jul 23, 2013
P4, N=4748, Completed, Sponsor: Ghana Health Services
- Trial completion: GhanaCommRDT: The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level (clinicaltrials.gov) - Jul 21, 2013
P4, N=4748, Completed, Sponsor: Ghana Health Services
Active, not recruiting --> Completed Not yet recruiting --> Completed
- ||| Mosquirix (RTS,S) / GSK
Enrollment closed: Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African Infants (clinicaltrials.gov) - Jul 17, 2013
P2, N=480, Active, not recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Completed Recruiting --> Active, not recruiting
- ||||||| Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi
Trial completion: Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria (clinicaltrials.gov) - Jul 16, 2013
P3, N=380, Completed, Sponsor: Sanofi
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- levetiracetam / Generic mfg.
Enrollment change: Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (clinicaltrials.gov) - Jul 15, 2013
P1/2, N=7, Completed, Sponsor: Michigan State University
Active, not recruiting --> Completed N=30 --> 7
- levetiracetam / Generic mfg.
Trial completion: Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (clinicaltrials.gov) - Jul 15, 2013
P1/2, N=7, Completed, Sponsor: Michigan State University
N=30 --> 7 Recruiting --> Completed
- Trial completion: Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteers (clinicaltrials.gov) - Jul 15, 2013
P1, N=36, Completed, Sponsor: Infectious Disease Research Institute
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment closed: CINEBENZ: Population Pharmacokinetics in Benznidazole-treated Adults With Chronic With Chagas Disease (clinicaltrials.gov) - Jul 7, 2013
P4, N=50, Active, not recruiting, Sponsor: Barcelona Centre for International Health Research
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion: The Healthcare Professionals and the Leishmaniasis (clinicaltrials.gov) - Jul 7, 2013
P=N/A, N=228, Completed, Sponsor: Centro de Pesquisas Ren
Recruiting --> Active, not recruiting Not yet recruiting --> Completed
- | New P4 trial: Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam (clinicaltrials.gov) - Jun 25, 2013
P4, N=330, Recruiting, Sponsor: Oxford University Clinical Research Unit, Vietnam
- Trial completion: DFPT: Treatment Study of Metronidazole to Treat Dientamoebiasis in Children (clinicaltrials.gov) - Jun 24, 2013
P4, N=100, Completed, Sponsor: Statens Serum Institut
Not yet recruiting --> Completed Recruiting --> Completed
- Trial suspension: ARGISM: Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria (clinicaltrials.gov) - Jun 23, 2013
P2, N=8, Suspended, Sponsor: Menzies School of Health Research
Recruiting --> Completed Recruiting --> Suspended
- Enrollment change: ARGISM: Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria (clinicaltrials.gov) - Jun 23, 2013
P2, N=8, Suspended, Sponsor: Menzies School of Health Research
Recruiting --> Suspended N=60 --> 8
- Enrollment open: Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam (clinicaltrials.gov) - Jun 23, 2013
P4, N=330, Recruiting, Sponsor: Oxford University Clinical Research Unit, Vietnam
N=60 --> 8 Not yet recruiting --> Recruiting
- Mosquirix (RTS,S) / GSK
New P1/2 trial: A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S (clinicaltrials.gov) - Jun 19, 2013
P1/2, N=46, Recruiting, Sponsor: University of Oxford
- | primaquine / Generic mfg.
New P4 trial: Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine (clinicaltrials.gov) - Jun 12, 2013
P4, N=1488, Completed, Sponsor: Indonesia University
- ||||||| Mosquirix (RTS,S) / GSK
Trial completion: Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children (clinicaltrials.gov) - Jun 11, 2013
P3, N=200, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | primaquine / Generic mfg.
Trial completion: Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda (clinicaltrials.gov) - Jun 10, 2013
P3, N=468, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Active, not recruiting --> Completed Recruiting --> Completed
- Enrollment open: Trichomonas Vaginalis Repeat Infections Among HIV Negative Women (clinicaltrials.gov) - Jun 9, 2013
P4, N=2883, Recruiting, Sponsor: Tulane University Health Sciences Center
Recruiting --> Completed Not yet recruiting --> Recruiting
- New P4 trial: DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women (clinicaltrials.gov) - Jun 6, 2013
P4, N=30, Recruiting, Sponsor: Tulane University Health Sciences Center
- PfSPZ Vaccine / Sanaria
Enrollment change: Experimental PfSPZ Vaccine in Adults Without Malaria (clinicaltrials.gov) - Jun 5, 2013
P1, N=64, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Recruiting N=30 --> 64
- PfSPZ Vaccine / Sanaria
Trial completion: Sanaria (clinicaltrials.gov) - Jun 5, 2013
P1, N=30, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
N=30 --> 64 Active, not recruiting --> Completed
- PfSPZ Vaccine / Sanaria
Trial completion: Experimental PfSPZ Vaccine in Adults Without Malaria (clinicaltrials.gov) - Jun 5, 2013
P1, N=64, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Euvax B (recombinant hepatitis B vaccine) / LG Chem, Menactra (Meningococcal-groups A, C, Y and W-135 polysaccharide diphtheria toxoid conjugate vaccine) / Sanofi
New P1/2 trial: Testing Pfs25-EPA/Alhydrogel as a Potential Malaria Transmission Blocking Vaccine (clinicaltrials.gov) - Jun 2, 2013
P1/2, N=350, Active, not recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- Lampit (nifurtimox) / Bayer
Trial completion: NECT-FIELD: Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic Phase (clinicaltrials.gov) - May 29, 2013
P4, N=630, Completed, Sponsor: Drugs for Neglected Diseases
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: PIMAL: Prenatal Iron and Malaria Study (clinicaltrials.gov) - May 27, 2013
P4, N=470, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Active, not recruiting --> Completed N=300 --> 470
- Trial completion: PIMAL: Prenatal Iron and Malaria Study (clinicaltrials.gov) - May 27, 2013
P4, N=470, Completed, Sponsor: London School of Hygiene and Tropical Medicine
N=300 --> 470 Recruiting --> Completed
- | Trial completion: SBMC: School Based Malaria Control in Ugandan Schoolchildren (clinicaltrials.gov) - May 21, 2013
P3, N=740, Completed, Sponsor: Makerere University
Recruiting --> Completed Active, not recruiting --> Completed
- chloroquine phosphate / Generic mfg.
Trial withdrawal: Prevention of P. Vivax Malaria During Pregnancy in Bolivia (clinicaltrials.gov) - May 20, 2013
P4, N=0, Withdrawn, Sponsor: Institut de Recherche pour le Developpement
Active, not recruiting --> Completed Not yet recruiting --> Withdrawn
- chloroquine phosphate / Generic mfg.
Enrollment change: Prevention of P. Vivax Malaria During Pregnancy in Bolivia (clinicaltrials.gov) - May 20, 2013
P4, N=0, Withdrawn, Sponsor: Institut de Recherche pour le Developpement
Not yet recruiting --> Withdrawn N=1600 --> 0
- | cipargamin (KAE609) / Novartis
Enrollment change: Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection (clinicaltrials.gov) - May 8, 2013
P2, N=27, Completed, Sponsor: Novartis Pharmaceuticals
N=1600 --> 0 N=20 --> 27
- Enrollment open: Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe Malaria (clinicaltrials.gov) - May 8, 2013
P=N/A, N=100, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
N=20 --> 27 Not yet recruiting --> Recruiting
- | cipargamin (KAE609) / Novartis
Trial completion: Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection (clinicaltrials.gov) - May 8, 2013
P2, N=27, Completed, Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Recruiting Recruiting --> Completed
- || Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi
New P3 trial: Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon (clinicaltrials.gov) - May 1, 2013
P3, N=720, Recruiting, Sponsor: University of Yaounde 1