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41 Companies |
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29 Products |
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29 Products |
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22 Mechanisms of Action |
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2 Trials |
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854 News |
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- Trial completion: Efficacy of Malaria Vaccines in Kenyan Adults (clinicaltrials.gov) - Dec 10, 2013
P2, N=120, Completed, Sponsor: University of Oxford
Active, not recruiting --> Completed
- Trial completion: Efficacy of Candidate Malaria Vaccines in Senegalese Adults (clinicaltrials.gov) - Dec 10, 2013
P2, N=120, Completed, Sponsor: University of Oxford
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion: AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area (clinicaltrials.gov) - Dec 10, 2013
P1, N=72, Completed, Sponsor: University of Oxford
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | New P4 trial: START-IPT: School-Based Treatment With ACT to Reduce Transmission (clinicaltrials.gov) - Dec 9, 2013
P4, N=25000, Not yet recruiting, Sponsor: London School of Hygiene and Tropical Medicine
- Trial completion: Malaria Studies in Cambodia (clinicaltrials.gov) - Dec 6, 2013
P=N/A, N=2765, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Recruiting --> Completed
- || chloroquine phosphate / Generic mfg., artemether/lumefantrine / Generic mfg.
New P3 trial: P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine (clinicaltrials.gov) - Dec 2, 2013
P3, N=110, Not yet recruiting, Sponsor: Menzies School of Health Research
- |||| Enrollment open: Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease (clinicaltrials.gov) - Dec 2, 2013
P4, N=102, Recruiting, Sponsor: Medtronic Cardiac Rhythm Disease Management
Recruiting --> Completed Not yet recruiting --> Recruiting
- | Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi
Enrollment change, Combination therapy: Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) (clinicaltrials.gov) - Nov 26, 2013
P3, N=219, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Not yet recruiting --> Recruiting N=300 --> 219
- | Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi
Trial completion, Combination therapy: Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) (clinicaltrials.gov) - Nov 26, 2013
P3, N=219, Completed, Sponsor: London School of Hygiene and Tropical Medicine
N=300 --> 219 Recruiting --> Completed
- Enrollment closed: MAL2: Malaria in Pregnancy: Nutrition and Immunologic Effects (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=2500, Active, not recruiting, Sponsor: Harvard School of Public Health
Recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion: MAL1: Prenatal Iron Supplements: Safety and Efficacy in Tanzania (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=1500, Completed, Sponsor: Harvard School of Public Health
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- gentamicin sulfate / Generic mfg.
New P2 trial: PAGELEC: WR 279,396 for the Treatment of Cutaneous Leishmaniasis (clinicaltrials.gov) - Nov 18, 2013
P2, N=30, Recruiting, Sponsor: Assistance Publique - H
- Lampit (nifurtimox) / Bayer
Enrollment open: Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' Patients (clinicaltrials.gov) - Nov 18, 2013
P1, N=36, Recruiting, Sponsor: Bayer
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- levetiracetam / Generic mfg.
New P2 trial: A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM (clinicaltrials.gov) - Nov 11, 2013
P2, N=30, Recruiting, Sponsor: University of Rochester
- Fexinidazole Winthrop (fexinidazole) / Sanofi
Enrollment open: Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in Sudan (clinicaltrials.gov) - Nov 11, 2013
P2, N=66, Recruiting, Sponsor: Drugs for Neglected Diseases
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||| Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
New P2 trial: A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria (clinicaltrials.gov) - Nov 10, 2013
P2, N=300, Recruiting, Sponsor: sigma-tau i.f.r. S.p.A.
- Trial completion: A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1 (clinicaltrials.gov) - Nov 7, 2013
P1/2, N=48, Completed, Sponsor: University of Oxford
Not yet recruiting --> Recruiting Recruiting --> Completed
- | Fexinidazole Winthrop (fexinidazole) / Sanofi
New P2 trial: Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in Sudan (clinicaltrials.gov) - Nov 6, 2013
P2, N=66, Recruiting, Sponsor: Drugs for Neglected Diseases
- ||| Trial completion: G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) (clinicaltrials.gov) - Nov 6, 2013
P1, N=192, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed Active, not recruiting --> Completed
- | artemether/lumefantrine / Generic mfg., mefloquine / Generic mfg.
New P4 trial, Combination therapy: In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy (clinicaltrials.gov) - Nov 4, 2013
P4, N=118, Enrolling by invitation, Sponsor: Global Emerging Infections Surveillance and Response System
- || hydroxyurea / Generic mfg.
New P3 trial: NOHARM: Novel Use Of Hydroxyurea in an African Region With Malaria (clinicaltrials.gov) - Nov 3, 2013
P3, N=200, Not yet recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
- |||| Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi
Trial completion: Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire (clinicaltrials.gov) - Nov 3, 2013
P4, N=580, Completed, Sponsor: Sanofi
Active, not recruiting --> Completed Recruiting --> Completed
- New P4 trial, IO biomarker: A Study to Explore Association of Treatment Regimens for Visceral Leishmaniasis, Host Immunological, Genetical and Nutrition Factors With Post-kala-azar Dermal Leishmaniasis (PKDL) (clinicaltrials.gov) - Oct 31, 2013
P4, N=36, Active, not recruiting, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
- Trial completion: Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women (clinicaltrials.gov) - Oct 30, 2013
P2, N=234, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Active, not recruiting --> Completed
- Trial completion: Impact of Enhanced Health Facility Care in Uganda (clinicaltrials.gov) - Oct 30, 2013
P4, N=25000, Completed, Sponsor: Uganda Malaria Surveillance Project
Active, not recruiting --> Completed Recruiting --> Completed
- artemether/lumefantrine / Generic mfg., mefloquine / Generic mfg.
Enrollment open, Combination therapy: In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy (clinicaltrials.gov) - Oct 29, 2013
P4, N=118, Enrolling by invitation, Sponsor: Global Emerging Infections Surveillance and Response System
Recruiting --> Completed Not yet recruiting --> Enrolling by invitation
- | ganaplacide (KAF156) / Novartis
Enrollment open: Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection (clinicaltrials.gov) - Oct 28, 2013
P2, N=40, Recruiting, Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- | Enrollment closed: Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study (clinicaltrials.gov) - Oct 27, 2013
P3, N=72, Active, not recruiting, Sponsor: Institute of Tropical Medicine, Belgium
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- albendazole / Generic mfg.
Trial initiation date: Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children (clinicaltrials.gov) - Oct 14, 2013
P=N/A, N=2377, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
Recruiting --> Active, not recruiting Initiation date: Sep 2012 --> Jan 2013
- albendazole / Generic mfg.
Enrollment change: Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children (clinicaltrials.gov) - Oct 14, 2013
P=N/A, N=2377, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
Initiation date: Sep 2012 --> Jan 2013 N=1450 --> 2377
- albendazole / Generic mfg.
Enrollment closed: Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children (clinicaltrials.gov) - Oct 14, 2013
P=N/A, N=2377, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
N=1450 --> 2377 Not yet recruiting --> Active, not recruiting
- Trial completion: Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection (clinicaltrials.gov) - Oct 14, 2013
P=N/A, N=2213, Completed, Sponsor: Medecins Sans Frontieres
Not yet recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment change: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma (clinicaltrials.gov) - Oct 10, 2013
P=N/A, N=43, Completed, Sponsor: Swiss Federal Institute of Technology
Active, not recruiting --> Completed N=80 --> 43
- Trial completion: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma (clinicaltrials.gov) - Oct 10, 2013
P=N/A, N=43, Completed, Sponsor: Swiss Federal Institute of Technology
N=80 --> 43 Active, not recruiting --> Completed
- Enrollment change, HEOR, Combination therapy, Cost effectiveness: Research on the Economics of Artemisinin Combination Therapy (ACTs) for the Treatment of Malaria (clinicaltrials.gov) - Oct 9, 2013
P=N/A, N=6513, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
Active, not recruiting --> Completed N=8900 --> 6513
- Enrollment closed, HEOR, Combination therapy, Cost effectiveness: Research on the Economics of Artemisinin Combination Therapy (ACTs) for the Treatment of Malaria (clinicaltrials.gov) - Oct 9, 2013
P=N/A, N=6513, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
N=8900 --> 6513 Recruiting --> Active, not recruiting
- | amodiaquine hydrochloride / Generic mfg.
New P2 trial: Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria (clinicaltrials.gov) - Oct 4, 2013
P2, N=200, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- || New P3 trial: High Dose Fluconazole in Cutaneous Leishmaniasis in Bahia and Manaus (clinicaltrials.gov) - Sep 29, 2013
P3, N=140, Not yet recruiting, Sponsor: Hospital Universit
- chloroquine phosphate / Generic mfg., primaquine / Generic mfg.
Enrollment open: Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan (clinicaltrials.gov) - Sep 24, 2013
P=N/A, N=50, Recruiting, Sponsor: Menzies School of Health Research
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- New P1 trial: Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib (clinicaltrials.gov) - Sep 23, 2013
P1, N=56, Recruiting, Sponsor: Centre Hospitalier Universitaire Vaudois
- | chloroquine phosphate / Generic mfg., sulfadoxine/pyrimethamine / Generic mfg., azithromycin / Generic mfg.
Trial termination: Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa (clinicaltrials.gov) - Sep 22, 2013
P3, N=2953, Terminated, Sponsor: Pfizer
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated; See termination reason in detailed description.
- | Enrollment change: Comparison of Standard and Alternative Antimonial Dosage in Patients With American Cutaneous Leishmaniasis (clinicaltrials.gov) - Sep 17, 2013
P3, N=264, Recruiting, Sponsor: Oswaldo Cruz Foundation
Active, not recruiting --> Terminated; See termination reason in detailed description. N=340 --> 264
- Trial completion: MATIAS: Malaria Treatment With Injectable ArteSunate (clinicaltrials.gov) - Sep 11, 2013
P=N/A, N=350, Completed, Sponsor: Swiss Tropical & Public Health Institute
N=340 --> 264 Not yet recruiting --> Completed
- Trial completion: Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia (clinicaltrials.gov) - Sep 11, 2013
P=N/A, N=415, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Completed Recruiting --> Completed
- || Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi
New P3 trial, Combination therapy: Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) (clinicaltrials.gov) - Sep 9, 2013
P3, N=219, Completed, Sponsor: London School of Hygiene and Tropical Medicine
- | primaquine / Generic mfg.
Enrollment open: LOPRIM: Low Dose Primaquine for Clearance of Gametocytes (clinicaltrials.gov) - Sep 9, 2013
P2/3, N=360, Recruiting, Sponsor: London School of Hygiene and Tropical Medicine
Recruiting --> Completed Not yet recruiting --> Recruiting
- Noxafil (posaconazole) / Merck (MSD)
Trial completion: CHAGASAZOL: Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And Benznidazole (clinicaltrials.gov) - Sep 8, 2013
P2, N=78, Completed, Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Not yet recruiting --> Recruiting Recruiting --> Completed
- ||| Enrollment change: Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse (clinicaltrials.gov) - Sep 4, 2013
P2, N=329, Active, not recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed N=924 --> 329
- || primaquine / Generic mfg.
New P2/3 trial: LOPRIM: Low Dose Primaquine for Clearance of Gametocytes (clinicaltrials.gov) - Sep 3, 2013
P2/3, N=360, Recruiting, Sponsor: London School of Hygiene and Tropical Medicine
- | Coarsucam (artesunate/amodiaquine) / Sanofi, DNDi, Mefliam Plus (artesunate/mefloquine) / Cipla, Oswaldo Cruz Foundation, DNDi, Eurartesim (dihydroartemisinin/piperaquine) / Medicines for Malaria Venture, Leadiant Biosci
Enrollment closed: PREGACT: Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria (clinicaltrials.gov) - Sep 3, 2013
P3, N=3480, Active, not recruiting, Sponsor: Institute of Tropical Medicine, Belgium
N=924 --> 329 Recruiting --> Active, not recruiting