|
10 Companies |
|
5 Products |
|
5 Products |
|
1 Mechanism of Action |
|
0 Trials |
|
131 News |
|
| 123» |
- | Phase classification: Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates (clinicaltrials.gov) - Sep 11, 2018
P1, N=41, Completed, Sponsor: Wake Forest University Health Sciences
Phase classification: P=N/A --> P1
- ||| Trial completion: Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients (clinicaltrials.gov) - Jan 18, 2018
P=N/A, N=100, Completed, Sponsor: Region Skane
Phase classification: P=N/A --> P1 Active, not recruiting --> Completed
- | murepavadin (POL7080) / Spexis
Trial completion: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia (clinicaltrials.gov) - Nov 28, 2017
P2, N=25, Completed, Sponsor: Polyphor Ltd.
Active, not recruiting --> Completed Terminated --> Completed
- | Phase classification: Efficacy Study of a Novel Device to Clean the Endotracheal Tube (clinicaltrials.gov) - Oct 18, 2017
P=N/A, N=74, Completed, Sponsor: Massachusetts General Hospital
Terminated --> Completed Phase classification: P2 --> P=N/A
- Enrollment change, Trial primary completion date: Pharmacodynamics Study of Imipenem in Patients With Ventilator Associated Pneumonia (clinicaltrials.gov) - Sep 20, 2017
P4, N=8, Completed, Sponsor: Prince of Songkla University
Phase classification: P2 --> P=N/A N=12 --> 8 | Trial primary completion date: Dec 2012 --> Aug 2013
- | Trial completion: VPLUS: Diagnostic Value of Lung Ultrasound for Ventilator-Associated Pneumonia (clinicaltrials.gov) - Sep 7, 2017
P=N/A, N=98, Completed, Sponsor: Groupe Hospitalier Paris Saint Joseph
N=12 --> 8 | Trial primary completion date: Dec 2012 --> Aug 2013 Recruiting --> Completed
- ||||||| NN1213 / Novo Nordisk
Trial completion: Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support (clinicaltrials.gov) - Aug 31, 2017
P3, N=500, Completed, Sponsor: Pfizer
Recruiting --> Completed No longer recruiting --> Completed
- | Trial termination, Trial primary completion date: The Gravity-VAP (Ventilator-Associated Pneumonia) Trial (clinicaltrials.gov) - Jun 16, 2017
P3, N=800, Terminated, Sponsor: Policlinico Hospital
No longer recruiting --> Completed Suspended --> Terminated | Trial primary completion date: Sep 2016 --> Apr 2015; Steering Committee accepted DSMB advise to terminate the study after review of data analysis at second interim analysis
- | chlorhexidine gluconate / Generic mfg.
Phase classification: P-VAPP: Prehospital Ventilator-Associated Pneumonia Prevention Trial (clinicaltrials.gov) - Jun 9, 2017
P=N/A, N=70, Completed, Sponsor: Nicholas M Mohr
Suspended --> Terminated | Trial primary completion date: Sep 2016 --> Apr 2015; Steering Committee accepted DSMB advise to terminate the study after review of data analysis at second interim analysis Phase classification: P2/3 --> P=N/A
- | Trial completion, Phase classification, Trial primary completion date: AirconVAP: Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial (clinicaltrials.gov) - May 25, 2017
P=N/A, N=190, Completed, Sponsor: Universit
Phase classification: P2/3 --> P=N/A Trial primary completion date: May 2011 --> Mar 2015 | Recruiting --> Completed | Phase classification: P4 --> PN/A
- | Trial completion, Phase classification: VICTOR: Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage (clinicaltrials.gov) - May 9, 2017
P=N/A, N=100, Completed, Sponsor: University of Turin, Italy
Trial primary completion date: May 2011 --> Mar 2015 | Recruiting --> Completed | Phase classification: P4 --> PN/A Recruiting --> Completed | Phase classification: P2/3 --> PN/A
- | Biomarker, Trial completion, Enrollment change, Trial primary completion date: Biomarkers in Patients Undergoing Mechanical Ventilation (clinicaltrials.gov) - Apr 4, 2017
P=N/A, N=211, Completed, Sponsor: Corporacion Parc Tauli
Recruiting --> Completed | Phase classification: P2/3 --> PN/A Recruiting --> Completed | N=400 --> 211 | Trial primary completion date: Apr 2014 --> Sep 2010
- | Biomarker, Trial completion: VAPRapid-2: Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (clinicaltrials.gov) - Mar 28, 2017
P=N/A, N=211, Completed, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Recruiting --> Completed | N=400 --> 211 | Trial primary completion date: Apr 2014 --> Sep 2010 Recruiting --> Completed
- | Trial completion, Trial primary completion date: AMYLASPI: Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients (clinicaltrials.gov) - Dec 5, 2016
P=N/A, N=24, Completed, Sponsor: University Hospital, Bordeaux
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Mar 2016
- Trial completion, Enrollment change, Trial primary completion date: Common Canister Protocol for Inhaler Administration in Mechanically Ventilated Patients (clinicaltrials.gov) - Oct 7, 2016
P4, N=354, Completed, Sponsor: Barnes-Jewish Hospital
Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Mar 2016 Enrolling by invitation --> Completed | N=258 --> 354 | Trial primary completion date: Feb 2014 --> Feb 2016
- Trial completion, Enrollment change, Trial primary completion date: Multi-center Observational Study to Evaluate Epidemiology and Resistance Patterns of Common ICU-Infections (MOSER) (clinicaltrials.gov) - Sep 1, 2016
P=N/A, N=381, Completed, Sponsor: Indian Society of Critical Care Medicine
Enrolling by invitation --> Completed | N=258 --> 354 | Trial primary completion date: Feb 2014 --> Feb 2016 Not yet recruiting --> Completed | N=200 --> 381 | Trial primary completion date: Nov 2011 --> Oct 2012
- colistin sulphate / Generic mfg.
Trial completion, Enrollment change: Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) (clinicaltrials.gov) - Aug 3, 2016
P=N/A, N=9, Completed, Sponsor: Charite University, Berlin, Germany
Not yet recruiting --> Completed | N=200 --> 381 | Trial primary completion date: Nov 2011 --> Oct 2012 Active, not recruiting --> Completed | N=12 --> 9
- murepavadin (POL7080) / Spexis
Trial termination, Trial primary completion date: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia (clinicaltrials.gov) - Jun 18, 2016
P2, N=25, Terminated, Sponsor: Polyphor Ltd.
Active, not recruiting --> Completed | N=12 --> 9 Recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2015
- ampicillin/sulbactam / Generic mfg.
Enrollment change, Trial withdrawal: NAVPRO: Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients (clinicaltrials.gov) - May 24, 2016
P4, N=0, Withdrawn, Sponsor: Hospital Pablo Tob
Recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2015 N=70 --> 0 | Suspended --> Withdrawn
- Trial completion, Enrollment change, Trial primary completion date: Serum Procalcitonin Study in the Management of Ventilated Patients (clinicaltrials.gov) - May 19, 2016
P=N/A, N=29, Completed, Sponsor: University of Missouri-Columbia
N=70 --> 0 | Suspended --> Withdrawn Recruiting --> Completed | N=250 --> 29 | Trial primary completion date: Aug 2010 --> Aug 2014
- Trial completion, Trial primary completion date: iVAP: Immune Suppression and Ventilator Associated Pneumonias (clinicaltrials.gov) - Apr 11, 2016
P=N/A, N=50, Completed, Sponsor: Matthew Exline
Recruiting --> Completed | N=250 --> 29 | Trial primary completion date: Aug 2010 --> Aug 2014 Enrolling by invitation --> Completed | Trial primary completion date: Jun 2014 --> Nov 2012
- Biomarker, Trial primary completion date: VAPRapid-2: Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (clinicaltrials.gov) - Mar 23, 2016
P=N/A, N=210, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Enrolling by invitation --> Completed | Trial primary completion date: Jun 2014 --> Nov 2012 Trial primary completion date: Jan 2016 --> Sep 2016
- Phase classification: Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates (clinicaltrials.gov) - Mar 10, 2016
P=N/A, N=41, Completed, Sponsor: Wake Forest School of Medicine
Trial primary completion date: Jan 2016 --> Sep 2016 Phase classification: P2 --> P=N/A
- ||| Trial completion, Trial primary completion date: Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=161, Completed, Sponsor: Hospitech Respiration
Phase classification: P2 --> P=N/A Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jul 2015
- | meropenem / Generic mfg., colistin sulphate / Generic mfg.
Trial completion, Enrollment change, Head-to-Head: MagicBullet: Trial of Colistin Versus Meropenem in Ventilator-associated Pneumonia (VAP) (CR-GNB) (clinicaltrials.gov) - Feb 3, 2016
P3, N=232, Completed, Sponsor: Fundaci
Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jul 2015 Active, not recruiting --> Completed | N=400 --> 232
- ||||||| Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie
Trial completion: A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia (clinicaltrials.gov) - Jan 26, 2016
P3, N=859, Completed, Sponsor: AstraZeneca
Active, not recruiting --> Completed | N=400 --> 232 Recruiting --> Completed
- Trial completion, Trial primary completion date: BestCuff: Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units (clinicaltrials.gov) - Dec 4, 2015
P4, N=326, Completed, Sponsor: University Hospital, Lille
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2017 --> Aug 2015
- murepavadin (POL7080) / Spexis
Trial primary completion date: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia (clinicaltrials.gov) - Nov 27, 2015
P2, N=25, Recruiting, Sponsor: Polyphor Ltd.
Recruiting --> Completed | Trial primary completion date: May 2017 --> Aug 2015 Trial primary completion date: Oct 2014 --> May 2016
- | meropenem / Generic mfg., colistin sulphate / Generic mfg.
Enrollment closed, Head-to-Head: MagicBullet: Trial of Colistin Versus Meropenem in Ventilator-associated Pneumonia (VAP) (CR-GNB) (clinicaltrials.gov) - Oct 30, 2015
P3, N=400, Active, not recruiting, Sponsor: Fundaci
Trial primary completion date: Oct 2014 --> May 2016 Recruiting --> Active, not recruiting
- || Trial primary completion date: Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients (clinicaltrials.gov) - Oct 27, 2015
P=N/A, N=100, Active, not recruiting, Sponsor: Region Skane
Recruiting --> Active, not recruiting Trial primary completion date: Jun 2015 --> Dec 2015
- | vancomycin / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Trial completion, Trial primary completion date: Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections (clinicaltrials.gov) - Sep 25, 2015
P3, N=252, Completed, Sponsor: Rabin Medical Center
Trial primary completion date: Jun 2015 --> Dec 2015 Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> May 2014
- Trial completion: Efficacy Study on Silver-coated ETT Cleaned With a Novel Device (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=41, Completed, Sponsor: Massachusetts General Hospital
Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> May 2014 Recruiting --> Completed
- Biomarker, Trial primary completion date: VAPRapid-2: Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (clinicaltrials.gov) - Aug 21, 2015
P=N/A, N=210, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Recruiting --> Completed Trial primary completion date: May 2015 --> Jan 2016
- Trial primary completion date: BestCuff: Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units (clinicaltrials.gov) - Aug 21, 2015
P4, N=312, Recruiting, Sponsor: University Hospital, Lille
Trial primary completion date: May 2015 --> Jan 2016 Trial primary completion date: Nov 2015 --> May 2017
- Trial completion: Comparison Between Two Methods of Oral Care on the Incidence of VAP (clinicaltrials.gov) - Jun 23, 2015
P=N/A, N=108, Completed, Sponsor: HaEmek Medical Center, Israel
Trial primary completion date: Nov 2015 --> May 2017 Not yet recruiting --> Completed
- || Trial primary completion date: Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System (clinicaltrials.gov) - Jun 18, 2015
P=N/A, N=200, Recruiting, Sponsor: Hospitech Respiration
Not yet recruiting --> Completed Trial primary completion date: Apr 2015 --> Dec 2015
- Trial suspension: The Gravity-VAP (Ventilator-Associated Pneumonia) Trial (clinicaltrials.gov) - Jun 11, 2015
P3, N=800, Suspended, Sponsor: Policlinico Hospital
Trial primary completion date: Apr 2015 --> Dec 2015 Recruiting --> Suspended
- Enrollment open, Trial primary completion date: AMYLASPI: Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=24, Recruiting, Sponsor: University Hospital, Bordeaux
Recruiting --> Suspended Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Oct 2015
- Trial completion: Tracheal Dosage of Amylase : a New Surrogate for Microaspirations in Ventilated ICU Patients (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=40, Completed, Sponsor: Universit
Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Oct 2015 Recruiting --> Completed
- || Enrollment closed, Trial primary completion date: Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients (clinicaltrials.gov) - May 6, 2015
P=N/A, N=100, Active, not recruiting, Sponsor: Region Skane
Recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Jun 2015
- Enrollment change, Trial termination: ASPIRE: Effect of Intermittent Versus Continuous Subglottic Secretion Drainage on Tracheal Mucosa Damages (clinicaltrials.gov) - May 1, 2015
P3, N=80, Terminated, Sponsor: Rennes University Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Jun 2015 N=126 --> 80 | Recruiting --> Terminated; Enrolment difficulties
- ||||| Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie
Enrollment change: A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia (clinicaltrials.gov) - Apr 15, 2015
P3, N=1000, Recruiting, Sponsor: AstraZeneca
N=126 --> 80 | Recruiting --> Terminated; Enrolment difficulties N=1494 --> 1000
- colistin sulphate / Generic mfg.
Enrollment closed, Trial primary completion date: Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) (clinicaltrials.gov) - Apr 9, 2015
P=N/A, N=12, Active, not recruiting, Sponsor: Charite University, Berlin, Germany
N=1494 --> 1000 Enrolling by invitation --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Apr 2015
- Enrollment open, Trial primary completion date: Efficacy Study on Silver-coated ETT Cleaned With a Novel Device (clinicaltrials.gov) - Mar 10, 2015
P=N/A, N=40, Recruiting, Sponsor: Massachusetts General Hospital
Enrolling by invitation --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Apr 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Jul 2015
- |||| Zavicefta (ceftazidime/avibactam) / Pfizer, AbbVie
Trial primary completion date: A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia (clinicaltrials.gov) - Feb 19, 2015
P3, N=1494, Recruiting, Sponsor: AstraZeneca
Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Jul 2015 Trial primary completion date: Jun 2016 --> Feb 2016
- Trial completion, Trial primary completion date: Clinical and Biological Markers in Acute Respiratory Failure (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=55, Completed, Sponsor: University of Athens
Trial primary completion date: Jun 2016 --> Feb 2016 Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Dec 2014
- | chlorhexidine gluconate / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: P-VAPP: Prehospital Ventilator-Associated Pneumonia Prevention Trial (clinicaltrials.gov) - Dec 6, 2014
P2/3, N=70, Completed, Sponsor: University of Iowa
Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Dec 2014 Recruiting --> Completed | N=50 --> 70 | Trial primary completion date: Jul 2014 --> Oct 2014
- Trial completion, Trial primary completion date: Can we Better Understand the Development of VAP and Eventually Predict and Prevent it? (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=286, Completed, Sponsor: University Hospital, Geneva
Recruiting --> Completed | N=50 --> 70 | Trial primary completion date: Jul 2014 --> Oct 2014 Recruiting --> Completed | Trial primary completion date: Jun 2014 --> Mar 2014
- || Trial primary completion date: Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System (clinicaltrials.gov) - Nov 18, 2014
P=N/A, N=200, Recruiting, Sponsor: Hospitech Respiration
Recruiting --> Completed | Trial primary completion date: Jun 2014 --> Mar 2014 Trial primary completion date: Dec 2014 --> Apr 2015
- Clinical: Oral Care as a Preventive Measure of VAP; Miswak Versus Chlorhexidine and Toothbrush. (clinicaltrials.gov) - Nov 12, 2014
P=N/A, N=40, Completed, Sponsor: Faculty of Medicine, University of Alexandria