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22 Companies |
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31 Products |
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31 Products |
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47 Mechanisms of Action |
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1 Trial |
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161 News |
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- Enrollment open: A Feasibility and Safety Study of the Use of a Dedicated Ballooned Intercostal Drain (clinicaltrials.gov) - Feb 4, 2014
P=N/A, N=20, Recruiting, Sponsor: Sherwood Forest Hospitals NHS Foundation Trust
Not yet recruiting --> Recruiting
- Avastin (bevacizumab) / Roche
New P2 trial: Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer (clinicaltrials.gov) - Feb 2, 2014
P2, N=30, Recruiting, Sponsor: Haihong Yang, MD, Pricipal investigator
- Trial initiation date: ADEPT: Investigation Into the Automated Drainage of Recurrent Effusions From the Pleural Space in Thoracic Malignancy. (clinicaltrials.gov) - Jan 28, 2014
P=N/A, N=8, Not yet recruiting, Sponsor: Sequana Medical AG
Not yet recruiting --> Recruiting Initiation date: Nov 2013 --> Mar 2014
- Enrollment open: Tubeless Versus Standard Upper Pole Percutaneous Nephrolithotomy (clinicaltrials.gov) - Jan 13, 2014
P=N/A, N=140, Recruiting, Sponsor: Rabin Medical Center
Initiation date: Nov 2013 --> Mar 2014 Not yet recruiting --> Recruiting
- |||| Trial completion: ASAP: Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter (clinicaltrials.gov) - Dec 26, 2013
P4, N=150, Completed, Sponsor: Duke University
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- saracatinib (AZD0530) / AstraZeneca
Enrollment change: AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer (clinicaltrials.gov) - Dec 17, 2013
P2, N=24, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed N=67 --> 24
- Trial completion, Biopsy: Pleural Cryobiopsies During Semirigid Thoracoscopy: A New Technique (clinicaltrials.gov) - Dec 2, 2013
P0, N=15, Completed, Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik
N=67 --> 24 Active, not recruiting --> Completed
- erlotinib / Generic mfg., docetaxel / Generic mfg., gemcitabine / Generic mfg.
Trial completion, Metastases: Elderly Independent Patients With Non Small Cell Lung Cancer (NSCLC) (clinicaltrials.gov) - Sep 28, 2013
P2, N=100, Completed, Sponsor: Groupe Francais De Pneumo-Cancerologie
Active, not recruiting --> Completed Terminated --> Completed
- |||| CBP501 / CanBas
Trial completion, Metastases: Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) (clinicaltrials.gov) - Jul 28, 2013
P2, N=201, Completed, Sponsor: CanBas Co. Ltd.
Terminated --> Completed Active, not recruiting --> Completed
- Trial termination, Metastases: IL-6 and IL-8 Level of Blood and Pleural Effusion During Chemotherapy in Metastatic Breast Cancer (clinicaltrials.gov) - Jul 23, 2013
P=N/A, N=9, Terminated, Sponsor: Fudan University
Active, not recruiting --> Completed Recruiting --> Terminated; it's too slow to enroll suitable patients into this study
- Enrollment change, Metastases: IL-6 and IL-8 Level of Blood and Pleural Effusion During Chemotherapy in Metastatic Breast Cancer (clinicaltrials.gov) - Jul 23, 2013
P=N/A, N=9, Terminated, Sponsor: Fudan University
Recruiting --> Terminated; it's too slow to enroll suitable patients into this study N=30 --> 9
- Recentin (cediranib) / AstraZeneca
Trial termination: Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion (clinicaltrials.gov) - Jul 11, 2013
P2, N=12, Terminated, Sponsor: Radboud University
N=30 --> 9 Completed --> Terminated
- Trial completion: Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion (clinicaltrials.gov) - Jul 10, 2013
P=N/A, N=360, Completed, Sponsor: All India Institute of Medical Sciences, New Delhi
Completed --> Terminated Active, not recruiting --> Completed
- Enrollment change, HEOR: Pleural Catheters Versus Thoracoscopic Pleurodesis (clinicaltrials.gov) - Jul 4, 2013
P=N/A, N=445, Recruiting, Sponsor: M.D. Anderson Cancer Center
Active, not recruiting --> Completed N=345 --> 445
- | Amnolake (tamibarotene) / Syros
Trial termination, Metastases: First Line Study of Tamibarotene in Combination for Advanced Non-Small Cell Lung Cancer (clinicaltrials.gov) - Jun 26, 2013
P2, N=140, Terminated, Sponsor: CytRx
N=345 --> 445 Active, not recruiting --> Terminated; Interim analysis showed that the primary endpoint would not be met.
- | Trial completion, Surgery: MesoVATS: Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma (clinicaltrials.gov) - Jun 26, 2013
P3, N=196, Completed, Sponsor: Papworth Hospital NHS Foundation Trust
Active, not recruiting --> Terminated; Interim analysis showed that the primary endpoint would not be met. Active, not recruiting --> Completed
- Clinical: POPULAR: POst-operative PULmonary Complications After Use of Muscle Relaxants in Europe (clinicaltrials.gov) - May 29, 2013
P=N/A, N=24000, Not yet recruiting, Sponsor: European Society of Anaesthesiology
- |||| ganitumab (AMG 479) / Takeda, ImmunityBio
Trial completion, Combination therapy: QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer (clinicaltrials.gov) - Apr 11, 2013
P1/2, N=204, Completed, Sponsor: Amgen
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, IO biomarker: Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Treatment Response of Pulmonary Tuberculosis (clinicaltrials.gov) - Feb 26, 2013
P=N/A, N=300, Completed, Sponsor: Chang Gung Memorial Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion: Pleural Fluid and Serum Procalcitonin in Patients With Parapneumonic Pleural Effusion (clinicaltrials.gov) - Feb 26, 2013
P=N/A, N=150, Completed, Sponsor: Chang Gung Memorial Hospital
Recruiting --> Completed Recruiting --> Completed
- Trial completion: A Trial of Rigid Versus Semirigid Thoracoscopy in the Evaluation of Exudative Pleural Effusions (clinicaltrials.gov) - Jan 8, 2013
P=N/A, N=70, Completed, Sponsor: Postgraduate Institute of Medical Education and Research
Recruiting --> Completed Recruiting --> Completed
- Clinical: Effects of Respiratory Physiotherapy on Pleural Effusion (clinicaltrials.gov) - Dec 25, 2012
P=N/A, N=112, Completed, Sponsor: Universidad de Granada
- Enrollment change, Head-to-Head: DARTT: Drainage Amount for Removal of Thoracostomy Tube (clinicaltrials.gov) - Oct 25, 2012
P=N/A, N=280, Active, not recruiting, Sponsor: University of California, Davis
Recruiting --> Completed N=232 --> 280
- Enrollment closed, Head-to-Head: DARTT: Drainage Amount for Removal of Thoracostomy Tube (clinicaltrials.gov) - Oct 25, 2012
P=N/A, N=280, Active, not recruiting, Sponsor: University of California, Davis
N=232 --> 280 Enrolling by invitation --> Active, not recruiting
- Trial completion: Outcome of Patients Undiagnosed Under Medical Thoracoscopy (clinicaltrials.gov) - Sep 23, 2012
P=N/A, N=355, Completed, Sponsor: Eskisehir Osmangazi University
Enrolling by invitation --> Active, not recruiting Recruiting --> Completed
- |||||| Avastin (bevacizumab) / Roche
Enrollment open, Pleural effusion, Metastases: Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer (clinicaltrials.gov) - Aug 26, 2012
P3, N=70, Recruiting, Sponsor: Chinese PLA General Hospital
Recruiting --> Completed Not yet recruiting --> Recruiting
- Surgery: Fortified Skimmed Mother's Milk in the Management of Chylothorax (clinicaltrials.gov) - Aug 23, 2012
P=N/A, N=50, Recruiting, Sponsor: Oregon Health and Science University
- | New P4 trial: Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion (clinicaltrials.gov) - Aug 20, 2012
P4, N=52, Recruiting, Sponsor: Grupo de Pesquisa em Pleura e Oncologia Toracica
- | dalotuzumab (MK 0646) / Merck (MSD), Pierre Fabre
Enrollment change, IO biomarker, Metastases: IMPACT study: MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer (clinicaltrials.gov) - Aug 13, 2012
P2, N=27, Active, not recruiting, Sponsor: University of Kansas
Not yet recruiting --> Recruiting N=62 --> 27
- | gefitinib / Generic mfg., docetaxel / Generic mfg.
Trial completion, Metastases: Phase II Study of Docetaxel + ZD1839 in Elderly Patients With Non-Small Cell Lung Cancer (clinicaltrials.gov) - Aug 13, 2012
P2, N=44, Completed, Sponsor: H. Lee Moffitt Cancer Center and Research Institute
N=62 --> 27 Active, not recruiting --> Completed
- |||||||||| Avastin (bevacizumab) / Roche
New P3 trial, Pleural effusion, Metastases: Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer (clinicaltrials.gov) - Aug 8, 2012
P3, N=70, Recruiting, Sponsor: Chinese PLA General Hospital
- saracatinib (AZD0530) / AstraZeneca
Trial completion: AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer (clinicaltrials.gov) - Jun 16, 2012
P2, N=24, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | naproxen / Generic mfg.
New P2 trial: The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection (clinicaltrials.gov) - Jun 4, 2012
P2, N=300, Recruiting, Sponsor: McMaster University
- Recentin (cediranib) / AstraZeneca
Enrollment change: Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion (clinicaltrials.gov) - Apr 9, 2012
P2, N=12, Terminated, Sponsor: Radboud University
Active, not recruiting --> Completed N=32 --> 12
- ||| Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
Trial completion: Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas (clinicaltrials.gov) - Apr 6, 2012
P=N/A, N=100, Completed, Sponsor: Midwest Pulmonary and Critical Care
N=32 --> 12 Recruiting --> Completed
- Trial completion, FDG PET, Metastases: FDG-Labeled PET Scan in Planning Chemotherapy in Treating Patients With Stage IIIB or IV Non-Small Cell Lung Cancer (clinicaltrials.gov) - Mar 29, 2012
P2, N=46, Completed, Sponsor: University of Washington
Recruiting --> Completed Active, not recruiting --> Completed
- |||| Caprelsa (vandetanib) / Sanofi
Trial completion, Combination therapy, Metastases: ZELIG: Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus Gemcitabine (clinicaltrials.gov) - Mar 19, 2012
P2, N=124, Completed, Sponsor: AstraZeneca
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial withdrawal: Identifying Early Lung Cancer Cells in Malignant Pleural Effusion Samples From Patients With Primary Lung Cancer (clinicaltrials.gov) - Mar 15, 2012
P=N/A, N=0, Withdrawn, Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Terminated --> Withdrawn
- Trial completion: Respiratory Mechanics and Pleural Effusion (clinicaltrials.gov) - Mar 6, 2012
P=N/A, N=60, Completed, Sponsor: Policlinico Hospital
Terminated --> Withdrawn Recruiting --> Completed
- Enrollment change: Respiratory Mechanics and Pleural Effusion (clinicaltrials.gov) - Dec 6, 2011
P=N/A, N=60, Completed, Sponsor: Policlinico Hospital
Recruiting --> Completed N=33 --> 60
- Enrollment open, Biopsy: Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study (clinicaltrials.gov) - Nov 20, 2011
P2/3, N=25, Recruiting, Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik
N=33 --> 60 Not yet recruiting --> Recruiting
- | Avastin (bevacizumab) / Roche
Trial completion, Combination therapy, Metastases: Dose Escalating Study With BAY43-9006 With Carboplatin, Paclitaxel and Bevacizumab in Untreated Stage IIIb Non-small Cell Lung Cancer (NSCLC) (clinicaltrials.gov) - Nov 20, 2011
P1, N=33, Completed, Sponsor: Bayer
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- New P2/3 trial, Biopsy: Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study (clinicaltrials.gov) - Nov 17, 2011
P2/3, N=25, Recruiting, Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik
- | Trial completion: Rigid Versus Semirigid Thoracoscopy in Diagnosing Pleural Diseases: a Randomized Study (clinicaltrials.gov) - Nov 9, 2011
P3, N=84, Completed, Sponsor: Ale
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Biomarker, Trial termination: Multiple Biomarkers in Undiagnosed Pleural Effusion (clinicaltrials.gov) - Nov 6, 2011
P=N/A, N=200, Terminated, Sponsor: Fujirebio Diagnostics, Inc.
Active, not recruiting --> Completed Recruiting --> Terminated; The study was terminated on completion of the Pilot Study phase.
- New P2 trial: Comparison of Thoracoscopic Talc Pleurodesis by Thoracic Epidural or General Anesthesia (clinicaltrials.gov) - Oct 27, 2011
P2, N=40, Completed, Sponsor: University of Rome Tor Vergata
- Trial completion: Procoagulant Activity in Patients With Community Acquired Pneumonia, Pleural Effusion and Empyema (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=75, Completed, Sponsor: Meir Medical Center
Recruiting --> Terminated; The study was terminated on completion of the Pilot Study phase. Active, not recruiting --> Completed
- Enrollment open: Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation (clinicaltrials.gov) - Aug 31, 2011
P=N/A, N=200, Recruiting, Sponsor: Santa Casa de Votuporanga
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | Selectikine (EMD 521873) / EMD Serono
Trial completion, Combination therapy, IO biomarker, Metastases: EMR 62235-002: EMD 521873 Plus Radiotherapy in Non Small Cell Lung Cancer (NSCLC) (clinicaltrials.gov) - Aug 9, 2011
P1, N=12, Completed, Sponsor: Merck KGaA
Not yet recruiting --> Recruiting Recruiting --> Completed
- imatinib / Generic mfg., paclitaxel / Generic mfg.
Trial completion, Metastases: Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer (clinicaltrials.gov) - Aug 9, 2011
P2, N=34, Completed, Sponsor: University of Washington
Recruiting --> Completed Active, not recruiting --> Completed