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99 Companies |
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114 Products |
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114 Products |
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61 Mechanisms of Action |
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11 Trials |
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1875 News |
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- Phase classification: Evaluation of Orthopedic Knee Measurement Using Lunar iDXA (clinicaltrials.gov) - Jun 22, 2017
P=N/A, N=36, Completed, Sponsor: GE Healthcare
Phase classification: P1/2 --> P=N/A
- Phase classification, Trial primary completion date: MagnumCRCT: A Multicentre Trial to Compare Two Articulating Bearing Surfaces as Used in Cementless Primary Hip Arthroplasty (clinicaltrials.gov) - Jun 21, 2017
P=N/A, N=130, Terminated, Sponsor: Zimmer Biomet
Phase classification: P1/2 --> P=N/A Phase classification: P4 --> P=N/A | Trial primary completion date: Nov 2022 --> Jul 2015
- ||| Enrollment closed, Trial primary completion date, Surgery: Multi-centre Study to Assess the Long-term Performance of the Deltamotion Cup System in Primary Hip Replacement Surgery (clinicaltrials.gov) - Jun 9, 2017
P4, N=250, Active, not recruiting, Sponsor: DePuy International
Phase classification: P4 --> P=N/A | Trial primary completion date: Nov 2022 --> Jul 2015 Recruiting --> Active, not recruiting | Trial primary completion date: May 2017 --> Dec 2019
- | Trial completion, HEOR: SPACE: Strategies for Prescribing Analgesics Comparative Effectiveness Trial (clinicaltrials.gov) - Jun 8, 2017
P=N/A, N=265, Completed, Sponsor: VA Office of Research and Development
Recruiting --> Active, not recruiting | Trial primary completion date: May 2017 --> Dec 2019 Active, not recruiting --> Completed
- | methylprednisolone acetate / Generic mfg.
Trial completion, Patient reported outcomes: Does Injection Site Matter? A Randomized Controlled Trial to Evaluate Efficacy of Knee Intraarticular Injections on Improval of Patient Reported Outcomes. (clinicaltrials.gov) - Jun 1, 2017
P4, N=60, Completed, Sponsor: University of Puerto Rico
Active, not recruiting --> Completed Recruiting --> Completed
- ||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial initiation date: BOTOX (clinicaltrials.gov) - May 31, 2017
P2, N=176, Completed, Sponsor: Allergan
Recruiting --> Completed Initiation date: Sep 2015 --> Oct 2014
- | Trial completion: RCT-OA: Effectiveness of Aquatic Physical Therapy for Knee Osteoarthritis Patients (clinicaltrials.gov) - May 25, 2017
P=N/A, N=60, Completed, Sponsor: Universidade Estadual de Londrina
Initiation date: Sep 2015 --> Oct 2014 Recruiting --> Completed
- ||| Trial completion, Phase classification, HEOR: VISHE13: Visionaire Health Economics Study Comparing Economic Outcomes Between Visionaire and Standard Instrumentation (clinicaltrials.gov) - May 25, 2017
P=N/A, N=52, Completed, Sponsor: Smith & Nephew, Inc.
Recruiting --> Completed Active, not recruiting --> Completed | Phase classification: P4 --> PN/A
- | Enrollment closed, Trial primary completion date, HEOR: VISHE13: Visionaire Health Economics Study Comparing Economic Outcomes Between Visionaire and Standard Instrumentation (clinicaltrials.gov) - May 23, 2017
P4, N=50, Active, not recruiting, Sponsor: Smith & Nephew, Inc.
Active, not recruiting --> Completed | Phase classification: P4 --> PN/A Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> May 2017
- | Trial completion, Enrollment change, Trial primary completion date: Effectiveness of Passive and Active ROM Exercises Following TKA (clinicaltrials.gov) - May 22, 2017
P=N/A, N=60, Completed, Sponsor: University of Rostock
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> May 2017 Recruiting --> Completed | N=90 --> 60 | Trial primary completion date: Apr 2015 --> Jan 2016
- | remifentanil / Generic mfg., duloxetine / Generic mfg.
Enrollment closed, Trial primary completion date: IPRO: Imaging Pain Relief in Osteoarthritis (clinicaltrials.gov) - May 16, 2017
P4, N=81, Active, not recruiting, Sponsor: University of Nottingham
Recruiting --> Completed | N=90 --> 60 | Trial primary completion date: Apr 2015 --> Jan 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Sep 2017
- ||| Trial completion, Phase classification: STEPS: A Single Time-Point Study to Evaluate the ConforMIS iTotal (clinicaltrials.gov) - May 15, 2017
P=N/A, N=873, Completed, Sponsor: ConforMIS, Inc.
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Sep 2017 Enrolling by invitation --> Completed | Phase classification: P4 --> PN/A
- | Trial primary completion date, Surgery: Evaluation of the TruMatch (clinicaltrials.gov) - May 12, 2017
P=N/A, N=64, Completed, Sponsor: University of Milan
Enrolling by invitation --> Completed | Phase classification: P4 --> PN/A Trial primary completion date: Jun 2014 --> Apr 2017
- | Trial completion: Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Articular Cartilage Defect (clinicaltrials.gov) - May 10, 2017
P1, N=20, Completed, Sponsor: Shenzhen Hornetcorn Bio-technology Company, LTD
Trial primary completion date: Jun 2014 --> Apr 2017 Active, not recruiting --> Completed
- | Trial primary completion date: Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty (clinicaltrials.gov) - May 9, 2017
P=N/A, N=32, Completed, Sponsor: Eric Ricchetti
Active, not recruiting --> Completed Trial primary completion date: Jun 2014 --> Dec 2015
- | Enrollment closed, Trial primary completion date: Ultrasound-guided Sacroiliac Joint Radiofrequency Ablation: A Pilot Study (clinicaltrials.gov) - May 9, 2017
P=N/A, N=31, Active, not recruiting, Sponsor: Western University, Canada
Trial primary completion date: Jun 2014 --> Dec 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Sep 2017
- ||||||| rofecoxib (TRM-201) / Tremeau Pharma
Trial completion: A Study of Two Approved Drugs in Patients With Osteoarthritis (0966-220)(COMPLETED) (clinicaltrials.gov) - May 8, 2017
P3, N=413, Completed, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Sep 2017 No longer recruiting --> Completed
- ||||||| rofecoxib (TRM-201) / Tremeau Pharma
Trial completion: A Study of Two Approved Drugs in Patients With Osteoarthritis (0966-219) (clinicaltrials.gov) - May 8, 2017
P3, N=395, Completed, Sponsor: Merck Sharp & Dohme Corp.
No longer recruiting --> Completed No longer recruiting --> Completed
- Enrollment closed: Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA (clinicaltrials.gov) - May 3, 2017
P=N/A, N=50, Active, not recruiting, Sponsor: Massachusetts General Hospital
No longer recruiting --> Completed Recruiting --> Active, not recruiting
- | Trial completion, Enrollment change: Effectiveness of Osteopathy in the Preoperative Treatment of Postoperative Pain in Patients Undergoing Total Knee Replacement (clinicaltrials.gov) - May 2, 2017
P=N/A, N=70, Completed, Sponsor: Hospital Ambroise Par
Recruiting --> Active, not recruiting Recruiting --> Completed | N=54 --> 70
- Trial termination: Feasibility of the Latella Implant System for Medial Osteoarthritis (OA) (clinicaltrials.gov) - Apr 28, 2017
P=N/A, N=11, Terminated, Sponsor: Cotera, Inc.
Recruiting --> Completed | N=54 --> 70 Active, not recruiting --> Terminated; Sponsor election
- allogeneic human umbilical cord-derived mesenchymal stem cells (huMSC) / Medistem Panama
Enrollment change, Trial withdrawal: Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis (clinicaltrials.gov) - Apr 28, 2017
P1/2, N=0, Withdrawn, Sponsor: Translational Biosciences
Active, not recruiting --> Terminated; Sponsor election N=40 --> 0 | Active, not recruiting --> Withdrawn
- huMSC-derived mesenchymal trophic factors (MTF) / Medistem Panama
Enrollment change, Trial withdrawal, Trial primary completion date: Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis (clinicaltrials.gov) - Apr 28, 2017
P1/2, N=0, Withdrawn, Sponsor: Translational Biosciences
N=40 --> 0 | Active, not recruiting --> Withdrawn N=40 --> 0 | Active, not recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Dec 2018
- Trial termination: Evaluation of the Latella Knee Implant System for Medial Osteoarthritis Pain Reduction (Latella-2 Study) (clinicaltrials.gov) - Apr 28, 2017
P=N/A, N=67, Terminated, Sponsor: Cotera, Inc.
N=40 --> 0 | Active, not recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Dec 2018 Active, not recruiting --> Terminated; Sponsor election
- | Enrollment closed, Enrollment change, Trial primary completion date: TMC/PyroDisk: PRCT: Ligament Reconstruction & Tendon Interposition With a Joint Spacer for Trapeziometacarpal OA (clinicaltrials.gov) - Apr 27, 2017
P=N/A, N=82, Active, not recruiting, Sponsor: Simon Fraser Orthopaedic Fund
Active, not recruiting --> Terminated; Sponsor election Recruiting --> Active, not recruiting | N=130 --> 82 | Trial primary completion date: Apr 2017 --> Nov 2017
- | Phase classification: Project JAY THA Registration Study (clinicaltrials.gov) - Apr 27, 2017
P=N/A, N=100, Completed, Sponsor: Smith & Nephew Orthopaedics (Beijing) Limited
Recruiting --> Active, not recruiting | N=130 --> 82 | Trial primary completion date: Apr 2017 --> Nov 2017 Phase classification: P3 --> P=N/A
- | Trial completion, Enrollment change, Trial primary completion date: A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis (clinicaltrials.gov) - Apr 27, 2017
P1/2, N=11, Completed, Sponsor: ProCore Ltd.
Phase classification: P3 --> P=N/A Recruiting --> Completed | N=18 --> 11 | Trial primary completion date: Dec 2014 --> Oct 2015
- ||| Trial completion: TC-A Registration Study (clinicaltrials.gov) - Apr 26, 2017
P=N/A, N=162, Completed, Sponsor: Smith & Nephew Medical (Shanghai) Ltd
Recruiting --> Completed | N=18 --> 11 | Trial primary completion date: Dec 2014 --> Oct 2015 Active, not recruiting --> Completed
- || Trial primary completion date: Prospective, Multiconfiguration Study to Assess Functional Performance of Primary Total Knee Arthroplasty System (clinicaltrials.gov) - Apr 25, 2017
P=N/A, N=1138, Active, not recruiting, Sponsor: DePuy Orthopaedics
Active, not recruiting --> Completed Trial primary completion date: Mar 2017 --> Sep 2017
- || Trial primary completion date: 10003 PRO Current Products (clinicaltrials.gov) - Apr 25, 2017
P=N/A, N=840, Active, not recruiting, Sponsor: DePuy Orthopaedics
Trial primary completion date: Mar 2017 --> Sep 2017 Trial primary completion date: Mar 2017 --> Sep 2017
- ||| Trial completion: R3 (clinicaltrials.gov) - Apr 25, 2017
P=N/A, N=158, Completed, Sponsor: Smith & Nephew, Inc.
Trial primary completion date: Mar 2017 --> Sep 2017 Active, not recruiting --> Completed
- | Trial primary completion date, MRI: MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain (clinicaltrials.gov) - Apr 24, 2017
P=N/A, N=170, Recruiting, Sponsor: University of Michigan
Active, not recruiting --> Completed Trial primary completion date: Oct 2016 --> Jul 2018
- |||| TPX-100 / OrthoTrophix
Trial completion, Trial primary completion date: A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees (clinicaltrials.gov) - Apr 21, 2017
P2, N=120, Completed, Sponsor: OrthoTrophix, Inc
Trial primary completion date: Oct 2016 --> Jul 2018 Active, not recruiting --> Completed | Trial primary completion date: May 2016 --> Sep 2016
- | Phase classification: Exploring Massage Benefits for Arthritis of the Knee (clinicaltrials.gov) - Apr 20, 2017
P=N/A, N=222, Completed, Sponsor: Duke University
Active, not recruiting --> Completed | Trial primary completion date: May 2016 --> Sep 2016 Phase classification: P2 --> P=N/A
- | Enrollment change, Trial withdrawal: Treatment of Chronic Pain From Osteoarthritis (clinicaltrials.gov) - Apr 19, 2017
P4, N=0, Withdrawn, Sponsor: IRCCS Policlinico S. Matteo
Phase classification: P2 --> P=N/A N=182 --> 0 | Recruiting --> Withdrawn
- | Enrollment closed: Supine Sleeping After Total Hip Replacement (clinicaltrials.gov) - Apr 19, 2017
P=N/A, N=456, Active, not recruiting, Sponsor: Orthopedisch Centrum Oost Nederland
N=182 --> 0 | Recruiting --> Withdrawn Recruiting --> Active, not recruiting
- | Trial completion, Surgery: Psychological, Sexually and Social Consequences of Osteoarthritis Treatment With THA or TKA and Joint Preserving Surgery (clinicaltrials.gov) - Apr 18, 2017
P=N/A, N=250, Completed, Sponsor: Hvidovre University Hospital
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | Trial completion, Trial primary completion date, Stroma: Mesenchymal Stromal Cells and Osteoarthritis (clinicaltrials.gov) - Apr 14, 2017
P=N/A, N=30, Completed, Sponsor: Technische Universit
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2010 --> Jun 2016
- Trial primary completion date: Regenexx (clinicaltrials.gov) - Apr 11, 2017
P=N/A, N=50, Active, not recruiting, Sponsor: Regenerative Sciences, LLC
Recruiting --> Completed | Trial primary completion date: Dec 2010 --> Jun 2016 Trial primary completion date: Dec 2016 --> Dec 2017
- | Trial completion: Attune-RSA: Kinematic Analysis of a PS, FB Primary Total Knee Arthroplasty (ATTUNE Knee System) Using Dynamic RSA (clinicaltrials.gov) - Apr 11, 2017
P=N/A, N=20, Completed, Sponsor: Istituto Ortopedico Rizzoli
Trial primary completion date: Dec 2016 --> Dec 2017 Active, not recruiting --> Completed
- | Prolia (denosumab) / Amgen, Daiichi Sankyo
Trial completion, Trial initiation date: Effects of Denosumab on Periprosthetic Bone After Total Hip Arthroplasty (clinicaltrials.gov) - Apr 7, 2017
P2, N=64, Completed, Sponsor: Hans Mallmin
Active, not recruiting --> Completed Active, not recruiting --> Completed | Initiation date: Mar 2012 --> Aug 2012
- | Enrollment closed: Staying Positive With Arthritis Study (clinicaltrials.gov) - Apr 6, 2017
P=N/A, N=600, Active, not recruiting, Sponsor: VA Office of Research and Development
Active, not recruiting --> Completed | Initiation date: Mar 2012 --> Aug 2012 Recruiting --> Active, not recruiting
- | Dynastat (parecoxib) / Pfizer
Trial completion, Trial primary completion date: Efficacy and Safety of Postoperative Intravenous Parecoxib Sodium Followed by Oral Celecoxib in Osteoarthritis Patients (clinicaltrials.gov) - Apr 5, 2017
P4, N=246, Completed, Sponsor: Peking Union Medical College Hospital
Recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: Jul 2016 --> Nov 2016
- | Trial primary completion date, Surgery: Occupational Therapy and Surgery in Carpometacarpal Osteoarthritis (clinicaltrials.gov) - Apr 4, 2017
P=N/A, N=180, Recruiting, Sponsor: National Resource Center for Rehabilitation in Rheumatology
Recruiting --> Completed | Trial primary completion date: Jul 2016 --> Nov 2016 Trial primary completion date: Mar 2016 --> Jun 2017
- Trial completion date: Safety of Non-delayed Weight Bearing After Total Hip Replacement With Non-Cemented Fiber Metal Taper Stem (clinicaltrials.gov) - Mar 31, 2017
P=N/A, N=33, Completed, Sponsor: Vanderbilt University Medical Center
Trial primary completion date: Mar 2016 --> Jun 2017 Trial completion date: Dec 2006 --> Nov 2007
- Trial termination, Trial primary completion date: A Randomised Single Centre Study to Compare the Long-term Performance of Acryloc (clinicaltrials.gov) - Mar 27, 2017
P4, N=36, Terminated, Sponsor: DePuy International
Trial completion date: Dec 2006 --> Nov 2007 Active, not recruiting --> Terminated | Trial primary completion date: Jan 2006 --> Oct 2005
- || Trial primary completion date: ABSOLUTE-R: Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee (clinicaltrials.gov) - Mar 27, 2017
P4, N=287, Completed, Sponsor: Chong Kun Dang Pharmaceutical
Active, not recruiting --> Terminated | Trial primary completion date: Jan 2006 --> Oct 2005 Trial primary completion date: Nov 2014 --> Oct 2016
- ||| Trial completion, Enrollment change, Trial initiation date: STAR 8: Post-Approval Study to Investigate the Long Term (8 Year) Survivorship of STAR Ankle Among Continued Access Study Patients (clinicaltrials.gov) - Mar 27, 2017
P=N/A, N=87, Completed, Sponsor: Stryker Trauma GmbH
Trial primary completion date: Nov 2014 --> Oct 2016 Enrolling by invitation --> Completed | N=125 --> 87 | Initiation date: Jan 2011 --> Oct 2009
- | Trial completion: Improving Services and Outcomes for Joint Replacement Patients (clinicaltrials.gov) - Mar 24, 2017
P=N/A, N=1900, Completed, Sponsor: South West Sydney Local Health District
Enrolling by invitation --> Completed | N=125 --> 87 | Initiation date: Jan 2011 --> Oct 2009 Active, not recruiting --> Completed
- | NN1213 / Novo Nordisk
Enrollment change: Prevention of Post-Traumatic Osteoarthritis (OA) (clinicaltrials.gov) - Mar 17, 2017
P=N/A, N=40, Completed, Sponsor: Ned Amendola
Active, not recruiting --> Completed N=56 --> 40