Osteoarthritis News - LARVOL Sigma

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61 Mechanisms of Action

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|||||||||| Trial termination, Head-to-Head, Surgery: PRECISE: PEAK PlasmaBlade 4.0 Versus Traditional Electrosurgery in Total Knee Replacement. (clinicaltrials.gov) - Dec 13, 2011
P=N/A, N=24, Terminated, Sponsor: Medtronic Surgical Technologies
Active, not recruiting --> Terminated; Termination due to acquisition of PEAK Surgical by Medtronic

|||||||||| New P3 trial: Echostim1: Echogenic Versus Stimulating Needle and Catheter for Sciatic Blocks (clinicaltrials.gov) - Dec 13, 2011
P3, N=70, Completed, Sponsor: Lawson Health Research Institute

|||||||||| New P2 trial: Guided Imagery Response in Total Knee Replacement (clinicaltrials.gov) - Dec 12, 2011
P2, N=82, Completed, Sponsor: Kent State University

|||||||||| Enrollment change: Patterned Electrical Neuromuscular Stimulation and Therapeutic Exercise for Osteoarthritis of the Knee: Pilot Study (clinicaltrials.gov) - Dec 7, 2011
P4, N=13, Completed, Sponsor: RS Medical
Active, not recruiting --> Terminated; Termination due to acquisition of PEAK Surgical by Medtronic N=20 --> 13

|||||||||| Trial completion: Patterned Electrical Neuromuscular Stimulation and Therapeutic Exercise for Osteoarthritis of the Knee: Pilot Study (clinicaltrials.gov) - Dec 7, 2011
P4, N=13, Completed, Sponsor: RS Medical
N=20 --> 13 Recruiting --> Completed

||||||||||  Zilretta (triamcinolone acetonide ER) / Pacira
New P2 trial:  Study of FX006 in Patients With Osteoarthritis of the Knee (clinicaltrials.gov) -  Dec 5, 2011
P2, N=229, Completed,  Sponsor: Flexion Therapeutics, Inc.

||||||||||  sprifermin (AS-902330) / TrialSpark
Trial completion, Surgery:  A Multicenter Study of rhFGF 18 in Patients With Knee Osteoarthritis Not Requiring Surgery (clinicaltrials.gov) -  Dec 5, 2011
P1, N=192, Completed,  Sponsor: EMD Serono
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial withdrawal: Retrospective Data Review of ReCap Total Hip Resurfacing (clinicaltrials.gov) - Dec 4, 2011
P=N/A, N=0, Withdrawn, Sponsor: Biomet, Inc.
Active, not recruiting --> Completed Terminated --> Withdrawn

|||||||||| Trial withdrawal: Clinical Evaluation on HA Coated Dynamic Hip Screws for Trochanteric Femoral Fractures (clinicaltrials.gov) - Dec 4, 2011
P=N/A, N=0, Withdrawn, Sponsor: Biomet, Inc.
Terminated --> Withdrawn Terminated --> Withdrawn

|||||||||| Biomarker, New P4 trial, Surgery: VOHO: Hydroxyethyl Starch and Renal Function After Hip Replacement Surgery (clinicaltrials.gov) - Dec 4, 2011
P4, N=42, Completed, Sponsor: Regional Hospital Holstebro

|||||||||| Enrollment change: Retrospective Study on Cenos Stem With BoneMaster HA (clinicaltrials.gov) - Dec 1, 2011
P=N/A, N=0, Withdrawn, Sponsor: Biomet, Inc.
Terminated --> Withdrawn N=100 --> 0

|||||||||| New P4 trial: Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet (clinicaltrials.gov) - Dec 1, 2011
P4, N=60, Not yet recruiting, Sponsor: Hvidovre University Hospital

|||||||||| New P1 trial: Autologous Stem Cells in Osteoarthritis (clinicaltrials.gov) - Dec 1, 2011
P1, N=30, Active, not recruiting, Sponsor: Hospital Universitario Dr. Jose E. Gonzalez

|||||||||| Enrollment closed: PBFR2: Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis (clinicaltrials.gov) - Nov 30, 2011
P=N/A, N=45, Active, not recruiting, Sponsor: University of Iowa
N=100 --> 0 Recruiting --> Active, not recruiting

|||||||||| New P4 trial: Columbia Shoulder Study (CSS) (clinicaltrials.gov) - Nov 28, 2011
P4, N=207, Completed, Sponsor: Columbia University

|||||||||| New P1/2 trial: Flexsure: A Study for Moderate Osteoarthritis of the Knee (clinicaltrials.gov) - Nov 22, 2011
P1/2, N=76, Completed, Sponsor: Vedic Lifesciences Pvt. Ltd.

|||||||||| Enrollment open: Ceramic-on-Ceramic Total Hip Arthroplasty and Squeaking: Influence of Component Design (clinicaltrials.gov) - Nov 21, 2011
P=N/A, N=204, Recruiting, Sponsor: Vejle Hospital
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting

|||||||||| Trial completion: Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial (clinicaltrials.gov) - Nov 21, 2011
P=N/A, N=178, Completed, Sponsor: Hospital for Special Surgery, New York
Not yet recruiting --> Recruiting No longer recruiting --> Completed

|||||||||| Trial completion, HEOR: Expectations, Satisfaction and Quality of Life in Total Hip Arthroplasty (clinicaltrials.gov) - Nov 21, 2011
P=N/A, N=405, Completed, Sponsor: Hospital for Special Surgery, New York
No longer recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Addressing Patients' Expectations of Total Knee Arthroplasty in a Randomized Trial (clinicaltrials.gov) - Nov 21, 2011
P=N/A, N=146, Completed, Sponsor: Hospital for Special Surgery, New York
No longer recruiting --> Completed No longer recruiting --> Completed

|||||||||| New P4 trial: Impact of Noninvasive Targeted Pulsed Electromagnetic Field (tPEMF) on Opioid Use, Pain, and Joint Function Following Total Knee Arthroplasty (clinicaltrials.gov) - Nov 17, 2011
P4, N=23, Terminated, Sponsor: Amp Orthopedics, Inc.

|||||||||| Enrollment closed: Evaluation of Orthopedic Knee Measurement Using Lunar iDXA (clinicaltrials.gov) - Nov 17, 2011
P1/2, N=40, Active, not recruiting, Sponsor: GE Healthcare
No longer recruiting --> Completed Recruiting --> Active, not recruiting

||||||||||  Belbuca (buprenorphine BEMA) / Collegium Pharma
Enrollment closed:  Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain (clinicaltrials.gov) -  Nov 17, 2011
P3, N=300, Active, not recruiting,  Sponsor: BioDelivery Sciences International
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting

|||||||||| New P2/3 trial: Efficacy of Omija (Schisandra Chinensis) Extract in Subjects With Knee Osteoarthritis (clinicaltrials.gov) - Nov 15, 2011
P2/3, N=60, Completed, Sponsor: Chonbuk National University Hospital

|||||||||| Trial completion: mdph: Efficacy and Tolerability of Mud Packs Therapy in Osteoarthritis of the Hand (clinicaltrials.gov) - Nov 15, 2011
P4, N=60, Completed, Sponsor: University of Siena
Recruiting --> Active, not recruiting Active, not recruiting --> Completed

||||||||||  Mucosta oral (rebamipide oral) / Otsuka, Kubota, Dongkwang
Trial completion:  PRESENT: PReventive Efficacy and Safety of rEbamipide on Nsaid Induced Mucosal Toxicity (clinicaltrials.gov) -  Nov 14, 2011
P3, N=396, Completed,  Sponsor: Korea Otsuka Pharmaceutical Co.,Ltd.
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| New P3 trial: Does Tourniquet Use in Total Knee Replacement Improve Fixation (clinicaltrials.gov) - Nov 2, 2011
P3, N=50, Completed, Sponsor: Per Aspenberg

||||||||||  Hydros (hyaluronan) / KalVista, Hydros TA (hyaluronan + triamcinolone) / KalVista
Trial completion:  Hydros Joint Therapy and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis (OA) (clinicaltrials.gov) -  Nov 1, 2011
P2, N=98, Completed,  Sponsor: Carbylan BioSurgery, Inc.
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  SAR 113945 / Sanofi
New P1 trial:  Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part I (clinicaltrials.gov) -  Oct 31, 2011
P1, N=24, Completed,  Sponsor: Sanofi

|||||||||| Enrollment open: ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee (clinicaltrials.gov) - Oct 31, 2011
P2/3, N=80, Recruiting, Sponsor: University Hospital of North Norway
Active, not recruiting --> Completed Not yet recruiting --> Recruiting

||||||||||  oxycodone/naloxone ER / Generic mfg.
Trial completion:  A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis (clinicaltrials.gov) -  Oct 31, 2011
P4, N=247, Completed,  Sponsor: Napp Pharmaceuticals Limited
Not yet recruiting --> Recruiting Active, not recruiting --> Completed

|||||||||| Enrollment change, Surgery: Signature Versus Computer Assisted Surgery Study (clinicaltrials.gov) - Oct 30, 2011
P=N/A, N=306, Enrolling by invitation, Sponsor: Biomet, Inc.
Active, not recruiting --> Completed N=50 --> 306

|||||||||| New P2 trial: Web-based Support to Manage Arthritis Pain (clinicaltrials.gov) - Oct 30, 2011
P2, N=228, Completed, Sponsor: Inflexxion, Inc.

|||||||||| Clinical: Evaluation of Functional Rehabilitation in Patients Undergoing Physiotherapy After Total Hip Arthroplasty (clinicaltrials.gov) - Oct 29, 2011
P=N/A, N=104, Completed, Sponsor: Hospital de Clinicas de Porto Alegre

||||||||||  Zorvolex (diclofenac) / Assertio
New P3 trial:  Study of Diclofenac Capsules to Treat Osteoarthritis Pain (clinicaltrials.gov) -  Oct 26, 2011
P3, N=307, Completed,  Sponsor: Iroko Pharmaceuticals, LLC

|||||||||| New P3 trial: A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip (clinicaltrials.gov) - Oct 24, 2011
P3, N=120, Completed, Sponsor: Hyben Vital ApS

|||||||||| New P2/3 trial: ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee (clinicaltrials.gov) - Oct 23, 2011
P2/3, N=80, Recruiting, Sponsor: University Hospital of North Norway

|||||||||| New P4 trial: Effectiveness Study of the Ivivi SofPulse for Pain Amelioration in Adults With Mild to Moderate Knee Osteoarthritis (clinicaltrials.gov) - Oct 20, 2011
P4, N=45, Terminated, Sponsor: Amp Orthopedics, Inc.

|||||||||| Clinical: Minimally Invasive Surgical Approaches In Total Knee Arthroplasty (clinicaltrials.gov) - Oct 19, 2011
P=N/A, N=40, Completed, Sponsor: Mayo Clinic

|||||||||| New P3 trial: Evaluation of Clinical Endpoints of Two Diclofenac Sodium Gel 1% (clinicaltrials.gov) - Oct 19, 2011
P3, N=749, Completed, Sponsor: Anchen Pharmaceuticals, Inc

|||||||||| New P2 trial: Allogeneic Mesenchymal Stem Cells in Osteoarthritis (clinicaltrials.gov) - Oct 16, 2011
P2, N=60, Active, not recruiting, Sponsor: Stempeutics Research Pvt Ltd

|||||||||| New P1/2 trial: Follow up Study of Patients Undergoing Total Hip Arthroplasty CERAFIT (clinicaltrials.gov) - Oct 16, 2011
P1/2, N=50, Not yet recruiting, Sponsor: Laboratoire Ceraver-Osteal

||||||||||  Ilaris (canakinumab) / Novartis
Trial completion:  To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee (clinicaltrials.gov) -  Oct 13, 2011
P2, N=169, Completed,  Sponsor: Novartis Pharmaceuticals
N=50 --> 306 Recruiting --> Completed

|||||||||| Trial completion: The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients (clinicaltrials.gov) - Oct 10, 2011
P2, N=40, Completed, Sponsor: TRB Chemedica
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: Influence of Whole Body Vibration Compared to Conventional Physiotherapy in Patients With Gonarthrosis (clinicaltrials.gov) - Oct 10, 2011
P=N/A, N=40, Completed, Sponsor: University of Cologne
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| Clinical: Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA) (clinicaltrials.gov) - Oct 6, 2011
P=N/A, N=80, Completed, Sponsor: Mahidol University

|||||||||| New P2 trial: Allogeneic Mesenchymal Stem Cells for Osteoarthritis (clinicaltrials.gov) - Oct 5, 2011
P2, N=72, Active, not recruiting, Sponsor: Stempeutics Research Pvt Ltd

|||||||||| Clinical: Effects of Foot Center of Pressure Manipulation on Hip Osteoarthritis Patients During Gait (clinicaltrials.gov) - Oct 2, 2011
P=N/A, N=60, Not yet recruiting, Sponsor: HaEmek Medical Center, Israel

||||||||||  ABT-652 / AbbVie
New P2 trial, Combination therapy:  A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee (clinicaltrials.gov) -  Sep 28, 2011
P2, N=202, Completed,  Sponsor: AbbVie (prior sponsor, Abbott)

|||||||||| Enrollment open, Surgery: Signature Versus Computer Assisted Surgery Study (clinicaltrials.gov) - Sep 27, 2011
P=N/A, N=306, Enrolling by invitation, Sponsor: Biomet, Inc.
Recruiting --> Completed Suspended --> Enrolling by invitation