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99 Companies |
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114 Products |
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114 Products |
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61 Mechanisms of Action |
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11 Trials |
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1875 News |
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- ||| Enrollment open: A Study of the Safety and Effectiveness of Synvisc-One (clinicaltrials.gov) - Sep 24, 2012
P=N/A, N=350, Recruiting, Sponsor: Genzyme, a Sanofi Company
Not yet recruiting --> Recruiting
- | Trial initiation date: STAR: Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension (clinicaltrials.gov) - Sep 20, 2012
P3, N=224, Active, not recruiting, Sponsor: University of Pittsburgh
Not yet recruiting --> Recruiting Initiation date: Mar 2011 --> Jan 2012
- Enrollment open: EXERPHARMA: The Effect on Knee Joint Loads of Analgesic Use Compared With Exercise in Patients With Knee Osteoarthritis - An RCT (clinicaltrials.gov) - Sep 20, 2012
P=N/A, N=100, Recruiting, Sponsor: University of Southern Denmark
Initiation date: Mar 2011 --> Jan 2012 Not yet recruiting --> Recruiting
- Trial completion: RTHA and THA: Gait Analysis and Neuromuscular Function After Primary Total Hip Replacement (clinicaltrials.gov) - Sep 20, 2012
P2, N=39, Completed, Sponsor: University of Southern Denmark
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | New P1 trial: Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment (clinicaltrials.gov) - Sep 19, 2012
P1, N=40, Recruiting, Sponsor: Northern Orthopaedic Division, Denmark
- Trial termination, Surgery: Group Exercise After Hip Replacement Surgery (clinicaltrials.gov) - Sep 18, 2012
P=N/A, N=19, Terminated, Sponsor: Norwegian University of Science and Technology
Active, not recruiting --> Completed Recruiting --> Terminated; recruitement unsuccessful
- Enrollment change, Surgery: Group Exercise After Hip Replacement Surgery (clinicaltrials.gov) - Sep 18, 2012
P=N/A, N=19, Terminated, Sponsor: Norwegian University of Science and Technology
Recruiting --> Terminated; recruitement unsuccessful N=54 --> 19
- ||||| V-116517 / Purdue
New P2 trial: Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee (clinicaltrials.gov) - Sep 18, 2012
P2, N=230, Completed, Sponsor: Purdue Pharma LP
- | Trial completion: Clinical Outcome of Birmingham Hip Resurfacing (BHR) Using VISIONAIRE Femoral Alignment Guide (clinicaltrials.gov) - Sep 16, 2012
P=N/A, N=25, Completed, Sponsor: Smith & Nephew, Inc.
N=54 --> 19 Recruiting --> Completed
- ||| Clinical: The Effects of Elmore Oil on Patients With Osteoarthritis (clinicaltrials.gov) - Sep 11, 2012
P=N/A, N=60, Completed, Sponsor: Elmore Oil Company Pty Ltd
- ||| Enrollment change: A Study to Determine the Performance of the Press Fit Condylar (P.F.C.) Sigma RP-F Knee System (clinicaltrials.gov) - Sep 10, 2012
P4, N=180, Active, not recruiting, Sponsor: DePuy International
Recruiting --> Completed N=150 --> 180
- ||||| gevokizumab (VPM087) / Novartis
New P2 trial: Safety and Biologic Activity Study of Gevokizumab to Treat Erosive Osteoarthritis of the Hand (clinicaltrials.gov) - Sep 9, 2012
P2, N=87, Completed, Sponsor: XOMA (US) LLC
- Trial completion: Obesity and the Initiation of Knee Osteoarthritis (clinicaltrials.gov) - Sep 6, 2012
P=N/A, N=177, Completed, Sponsor: Department of Veterans Affairs
N=150 --> 180 Recruiting --> Completed
- Trial withdrawal: The Effects of the Electro, Heat and Cold -Therapy During Physiotherapy Treatment in Osteoarthritis(OA) of KNEE (clinicaltrials.gov) - Sep 5, 2012
P1, N=0, Withdrawn, Sponsor: Meir Medical Center
Recruiting --> Completed Recruiting --> Withdrawn
- Enrollment change: The Effects of the Electro, Heat and Cold -Therapy During Physiotherapy Treatment in Osteoarthritis(OA) of KNEE (clinicaltrials.gov) - Sep 5, 2012
P1, N=0, Withdrawn, Sponsor: Meir Medical Center
Recruiting --> Withdrawn N=60 --> 0
- Clinical: Telephone Interview Study for Men and Women With Osteoarthritis (clinicaltrials.gov) - Sep 5, 2012
P=N/A, N=23, Completed, Sponsor: Health Outcomes Solutions
- Trial termination: INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation (clinicaltrials.gov) - Aug 29, 2012
P=N/A, N=24, Terminated, Sponsor: Wright Medical Technology
N=60 --> 0 Active, not recruiting --> Terminated; The retrospective data review did not provide adequate information to continue the investigation.
- Enrollment change: INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation (clinicaltrials.gov) - Aug 29, 2012
P=N/A, N=24, Terminated, Sponsor: Wright Medical Technology
Active, not recruiting --> Terminated; The retrospective data review did not provide adequate information to continue the investigation. N=95 --> 24
- epinephrine / Generic mfg.
Trial termination: Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine (clinicaltrials.gov) - Aug 28, 2012
P=N/A, N=33, Terminated, Sponsor: Rush University Medical Center
N=95 --> 24 Recruiting --> Terminated; Prohibitively expensive and efficacy of tranexamic acid rendered topic clinically less relevant.
- epinephrine / Generic mfg.
Enrollment change: Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine (clinicaltrials.gov) - Aug 28, 2012
P=N/A, N=33, Terminated, Sponsor: Rush University Medical Center
Recruiting --> Terminated; Prohibitively expensive and efficacy of tranexamic acid rendered topic clinically less relevant. N=240 --> 33
- || Enrollment change: Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement (clinicaltrials.gov) - Aug 28, 2012
P=N/A, N=72, Completed, Sponsor: Rush University Medical Center
N=240 --> 33 N=90 --> 72
- ||| Trial completion: Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement (clinicaltrials.gov) - Aug 28, 2012
P=N/A, N=72, Completed, Sponsor: Rush University Medical Center
N=90 --> 72 Active, not recruiting --> Completed
- Trial completion: Walking Aids in the Management of Hip Osteoarthritis (clinicaltrials.gov) - Aug 28, 2012
P=N/A, N=26, Completed, Sponsor: Arthritis Foundation
Active, not recruiting --> Completed Active, not recruiting --> Completed
- New P3 trial: Allograft Transplantation in the Treatment of Osteoarthritis of the Metatarsophalangeal (MTP) Joint of the Great Toe (clinicaltrials.gov) - Aug 26, 2012
P3, N=50, Recruiting, Sponsor: Paul Fortin, MD
- |||||| Invossa (tonogenchoncel-L) / Kolon Life Sci
New P2b trial: Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis (clinicaltrials.gov) - Aug 21, 2012
P2b, N=54, Completed, Sponsor: Kolon Life Science
- | SAR 113945 / Sanofi
Trial completion: Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part I (clinicaltrials.gov) - Aug 21, 2012
P1, N=24, Completed, Sponsor: Sanofi
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | New P4 trial: KNEEJECT: Platelet-rich Plasma vs Viscosupplementation in the Treatment of Knee Articular Degenerative Pathology (clinicaltrials.gov) - Aug 20, 2012
P4, N=192, Active, not recruiting, Sponsor: Istituto Ortopedico Rizzoli
- |||| Enrollment open, Surgery: Multi-centre Study to Assess the Long-term Performance of the Deltamotion Cup System in Primary Hip Replacement Surgery (clinicaltrials.gov) - Aug 20, 2012
P4, N=250, Recruiting, Sponsor: DePuy International
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | lutikizumab (ABT 981) / AbbVie
New P1 trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABT-981 in Patients With Osteoarthritis of the Knee (clinicaltrials.gov) - Aug 16, 2012
P1, N=36, Completed, Sponsor: AbbVie (prior sponsor, Abbott)
- | New P4 trial: Evaluation of the Use of Spinal Epimorph in Total Knee Arthroplasty (clinicaltrials.gov) - Aug 15, 2012
P4, N=138, Recruiting, Sponsor: Lawson Health Research Institute
- Enrollment change: A Clinical Investigation of the Copeland (clinicaltrials.gov) - Aug 13, 2012
P=N/A, N=34, Terminated, Sponsor: Biomet Orthopedics, LLC
Not yet recruiting --> Recruiting N=160 --> 34
- | oral calcitonin (SMC021) / Novo Nordisk
Trial termination: Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study) (clinicaltrials.gov) - Aug 12, 2012
P3, N=1030, Terminated, Sponsor: Nordic Bioscience A/S
N=160 --> 34 Completed --> Terminated; Male subjects were terminated due to an imbalance in prostate cancer events
- || Enrollment closed: Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA) (clinicaltrials.gov) - Aug 9, 2012
P=N/A, N=120, Active, not recruiting, Sponsor: Technische Universit
Completed --> Terminated; Male subjects were terminated due to an imbalance in prostate cancer events Recruiting --> Active, not recruiting
- |||| buprenorphine transdermal / Generic mfg.
Trial completion: Norspan Efficacy and Safety Among Elderly Subjects (clinicaltrials.gov) - Aug 7, 2012
P4, N=102, Completed, Sponsor: Mundipharma AB
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion: Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis (clinicaltrials.gov) - Aug 7, 2012
P=N/A, N=144, Completed, Sponsor: Cleveland Chiropractic College
Recruiting --> Completed Terminated --> Completed
- Trial termination: Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA) (clinicaltrials.gov) - Aug 5, 2012
P4, N=26, Terminated, Sponsor: Aesculap AG
Terminated --> Completed Recruiting --> Terminated; Number of patients willing to participate in the study too low
- Enrollment change: Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA) (clinicaltrials.gov) - Aug 5, 2012
P4, N=26, Terminated, Sponsor: Aesculap AG
Recruiting --> Terminated; Number of patients willing to participate in the study too low N=50 --> 26
- ||| Enrollment closed: Long-term Clinical Effectiveness of the Delta Xtend Reverse Total Shoulder (clinicaltrials.gov) - Aug 5, 2012
P4, N=250, Active, not recruiting, Sponsor: DePuy International
N=50 --> 26 Recruiting --> Active, not recruiting
- ||| Clinical: A Single-Center, Epidemiological Study of the Survivorship of the DePuy Sigma HP Unicompartmental Knee Prosthesis (clinicaltrials.gov) - Aug 1, 2012
P=N/A, N=300, Enrolling by invitation, Sponsor: Mississippi Sports Medicine and Orthopaedic Center
- || New P2/3 trial: Use of a Novel Fibrin Sealant in Total Knee Arthroplasty (clinicaltrials.gov) - Aug 1, 2012
P2/3, N=140, Recruiting, Sponsor: Rush University Medical Center
- |||| Trial completion: Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee (clinicaltrials.gov) - Jul 31, 2012
P4, N=59, Completed, Sponsor: CherryPharm
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Clinical: Methotrexate in Symptomatic Knee Osteoarthritis (clinicaltrials.gov) - Jul 30, 2012
P=N/A, N=88, Completed, Sponsor: Faculty of Medicine, University of Alexandria
- | Synera (lidocaine 70 mg/tetracaine 70 mg/heated Topical Patch) / Miravo, Eurocept, Galen, Samaritan Pharma
New P1/2 trial: Efficacy and Safety of Synera in Osteoarthritis Pain (clinicaltrials.gov) - Jul 29, 2012
P1/2, N=40, Recruiting, Sponsor: Thomas J. Schnitzer
- | Trial completion: A Comparison of Wear Among Mobile and Fixed Bearing Knee Replacements (clinicaltrials.gov) - Jul 29, 2012
P=N/A, N=24, Completed, Sponsor: Anderson Orthopaedic Research Institute
Active, not recruiting --> Completed Enrolling by invitation --> Completed
- ||| Trial completion: Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty (clinicaltrials.gov) - Jul 29, 2012
P=N/A, N=236, Completed, Sponsor: Anderson Orthopaedic Research Institute
Enrolling by invitation --> Completed Active, not recruiting --> Completed
- Kenalog-40 (triamcinolone acetonide injection suspension) / BMS, Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Enrollment change: Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint (clinicaltrials.gov) - Jul 26, 2012
P4, N=60, Suspended, Sponsor: University of Missouri-Columbia
Active, not recruiting --> Completed N=45 --> 60
- || tranexamic acid oral / Generic mfg.
New P2/3 trial: Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty (clinicaltrials.gov) - Jul 25, 2012
P2/3, N=120, Recruiting, Sponsor: Rush University Medical Center
- LeukoScan (sulesomab) / Gilead
Enrollment open: ISEOD: PET/CT Scanning for the Follow-up of Antibiotic Treatment of Infectious Osteoarthritis in the Diabetic Foot (clinicaltrials.gov) - Jul 25, 2012
P=N/A, N=109, Recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
N=45 --> 60 Not yet recruiting --> Recruiting
- ||||||| Humira (adalimumab) / AbbVie
Trial completion: DORA: Efficacy Study of an Anti-Tumor Necrosis Factor (TNF) Alpha Agent in Patients With Hand Osteoarthritis (clinicaltrials.gov) - Jul 24, 2012
P3, N=84, Completed, Sponsor: Assistance Publique - H
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment closed: MOLOS: Molecular Microbiology in Osteo-arthritis Infection (clinicaltrials.gov) - Jul 19, 2012
P=N/A, N=284, Active, not recruiting, Sponsor: Assistance Publique - H
Active, not recruiting --> Completed Recruiting --> Active, not recruiting