Ocular Melanoma MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	2	4	6	8	10	12	14	16	18	20



Immunostimulant




Tubulin inhib




VEGF-A inhib




VEGF-B inhib




Tubulin inhib




CD3 agon




CTLA4 inhib




DNA synthesis inhib




c-KIT inhib




TIE-2 inhib




mTOR inhib




Bcl2 inhib




Bcl2 inhib




HDAC2 inhib




MEK2 inhib




MEK2 inhib




PDGFR inhib




PKC inhib




Beta radiation emitter




Dendritic cell activator




IFNα 2b stim




IGF-1R inhib




IL-6 inhib




PD1 inhib




PIGF inhib




Steroid receptor agon




TLR9 agon




TNFα inhib




AKT inhib




Arginine depleter




BRAF inhib




DEC-205 agon




EGFR inhib




GABA uptake inhib




GCR agon




GPNMB-targeted antibody-drug conjugate




HIF-1 inhib




HSP90 inhib




IFIH1 mod




IL-10 stim




IL-12 inhib




IL-1β inhib




IL-2 stim




IL-6 inhib




PI3Kα inhib




Proteasome inhib




RAF kinase inhib




SSTR agon




STAT3 inhib




Somatostatin inhib



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