Obesity, Morbid MOAs - LARVOL Sigma

Obesity, Morbid

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20 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	1										2										3										4										5										6										7										8										9										10



µ-opioid agon




AMPA receptor antag




Carbonic anhydrase inhib




GABA A receptor agon




Glutamate receptor antag




Kainic acid receptor antag




NMDAR antag




Na+ channel antag




APOB100 gene expression inhib




Adrenergic receptor agon




Anorectic




DGAT inhib




DGAT-2 inhib




EGFR inhib




EGFR inhib




Fatty acid inhib




GHR agon




GLP-1 receptor agon




GLP-2 stim




IFN I stim




JNK inhib




NF-κB inhib




SREBP1 inhib




SREBP2 inhib




T-cell stim