- |||||||||| Journal: Congenital myasthenic syndrome due to a genetic mutation. (Pubmed Central) - Aug 1, 2023
As a result of the patient's good compliance with treatment, he was not admitted to hospital because of respiratory distress. The lack of a unified protocol for the treatment of CMS highlights the need for a more personalized approach when dealing with patients with rare diseases.
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Journal: Cyclosporine-induced erythromelalgia. (Pubmed Central) - Jul 31, 2023 Although exact mechanism for this rare adverse effect is unclear, it is reversible, and so clinicians should be aware of the association . Additional use of corticosteroids could aggravate cyclosporine's toxic effects.
- |||||||||| Review, Journal: Myasthenia gravis. Update on diagnosis and therapy. (Pubmed Central) - Jul 31, 2023
The increase in the knowledge of the immunological components of the neuromuscular junction in the last two decades has been fundamental to identify new pathogenic antibodies, reduce the percentage of patients with seronegative myasthenia, and propose a classification of patients into subgroups with clinical-therapeutic interest. In addition, in recent years, new drugs have been developed for the treatment of patients with myasthenia gravis that are refractory to conventional immunosuppressive treatment.
- |||||||||| Journal: Triple furrowed tongue in myasthenia gravis. (Pubmed Central) - Jul 31, 2023
In addition, in recent years, new drugs have been developed for the treatment of patients with myasthenia gravis that are refractory to conventional immunosuppressive treatment. No abstract available
- |||||||||| Role of Esophagogastroduodenoscopy in Evaluation of Progressive Neuromuscular Dysphagia (Exhibit Hall) - Jul 29, 2023 - Abstract #ACG2023ACG_3708;
Using multivariable logistic regression adjusting for male sex, age, and clinical frailty scale, ALS diagnosis (OR 0.20, 95% CI: 0.07-0.52, p=0.0011) and Neurology referral source (OR 0.37, 95% CI: 0.17-0.84, p=0.0177) were predictive of no initial EGD recommendation. ALS diagnosis was associated with gastrostomy placement (HR 10.39, 95% CI: 5.34-20.19, p< 0.0001).
- |||||||||| Preclinical, Review, Journal: An Overview of the Development and Preclinical Evaluation of Antibody-Drug Conjugates for Non-Oncological Applications. (Pubmed Central) - Jul 29, 2023
This current review focuses on the non-oncological applications of antibody-drug conjugates, their developmental studies, testing procedures, in vitro evaluations, and pre-clinical testing. Additionally, a summary of the restrictions, difficulties, and prospects for ADCs in non-oncological applications is provided.
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