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23 Companies |
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15 Products |
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15 Products |
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15 Mechanisms of Action |
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0 Trials |
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191 News |
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- |||| Medytoxin (botulinum toxin type A) / Medytox
Trial completion: The Efficacy and Safety of MEDITOXIN (clinicaltrials.gov) - Apr 20, 2019
P4, N=212, Completed, Sponsor: Medy-Tox
Recruiting --> Completed
- | baclofen / Generic mfg.
Trial completion date, Trial primary completion date: Long-term Surveillance of the MedStream Programmable Infusion System (clinicaltrials.gov) - Jan 23, 2019
P=N/A, N=2, Terminated, Sponsor: Codman & Shurtleff
Recruiting --> Completed Trial completion date: Jul 2020 --> Dec 2017 | Trial primary completion date: Feb 2020 --> Dec 2017
- | Trial completion, Trial completion date, Trial primary completion date: Optical Stimulation in Peripheral Nerves for Select Rhizotomy Procedures (clinicaltrials.gov) - May 1, 2018
P=N/A, N=19, Completed, Sponsor: Vanderbilt University
Trial completion date: Jul 2020 --> Dec 2017 | Trial primary completion date: Feb 2020 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Jan 2020 --> Nov 2017 | Trial primary completion date: Jan 2020 --> Nov 2017
- | Trial completion, Enrollment change, Trial primary completion date: tDCS(HE): Effects of tDCS on Quadriceps Strength After Stroke (clinicaltrials.gov) - Nov 14, 2017
P=N/A, N=14, Completed, Sponsor: Centre d'Investigation Clinique et Technologique 805
Active, not recruiting --> Completed | Trial completion date: Jan 2020 --> Nov 2017 | Trial primary completion date: Jan 2020 --> Nov 2017 Recruiting --> Completed | N=30 --> 14 | Trial primary completion date: Mar 2017 --> Nov 2016
- ||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion: ASPIRE: An Adult Spasticity Registry of OnabotulinumtoxinA Treatment (clinicaltrials.gov) - Oct 13, 2017
P=N/A, N=746, Completed, Sponsor: Allergan
Recruiting --> Completed | N=30 --> 14 | Trial primary completion date: Mar 2017 --> Nov 2016 Active, not recruiting --> Completed
- | dronabinol oral / Generic mfg.
Trial initiation date, Trial primary completion date: Cannabis for Spasticity in Multiple Sclerosis (clinicaltrials.gov) - Sep 26, 2017
P1/2, N=42, Terminated, Sponsor: University of California, Davis
Active, not recruiting --> Completed Initiation date: Mar 2003 --> Nov 2003 | Trial primary completion date: Jul 2017 --> Feb 2015
- ||||||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion: BOTOX (clinicaltrials.gov) - Sep 6, 2017
P3, N=384, Completed, Sponsor: Allergan
Initiation date: Mar 2003 --> Nov 2003 | Trial primary completion date: Jul 2017 --> Feb 2015 Recruiting --> Completed
- ||||||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion: BOTOX (clinicaltrials.gov) - Sep 6, 2017
P3, N=235, Completed, Sponsor: Allergan
Recruiting --> Completed Recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: Hypertonia in Patients With Cerebral Palsy (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=100, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting --> Completed Recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: Physiologic Studies of Spasticity (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=48, Completed, Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting --> Completed Recruiting --> Completed
- ||| Trial completion: ISPR: Implantable Systems Performance Registry (clinicaltrials.gov) - Apr 21, 2017
P=N/A, N=10981, Completed, Sponsor: MedtronicNeuro
Recruiting --> Completed Recruiting --> Completed
- | Enrollment closed, Trial primary completion date: Optical Stimulation in Peripheral Nerves for Select Rhizotomy Procedures (clinicaltrials.gov) - Apr 17, 2017
P=N/A, N=19, Active, not recruiting, Sponsor: Vanderbilt University
Recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Jan 2020
- | Xeomin (incobotulinumtoxinA) / Merz Pharma
Trial completion, Trial primary completion date: Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients (clinicaltrials.gov) - Mar 22, 2017
P4, N=27, Completed, Sponsor: Multiple Sclerosis Center of Northeastern New York
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Jan 2020 Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jan 2016
- | Sativex (nabiximols) / Jazz
Trial primary completion date: Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease (clinicaltrials.gov) - Mar 9, 2017
P2/3, N=60, Completed, Sponsor: Ospedale San Raffaele
Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jan 2016 Trial primary completion date: Sep 2014 --> Dec 2015
- ||||||| Xeomin (incobotulinumtoxinA) / Merz Pharma
Trial completion: Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy (clinicaltrials.gov) - Jan 26, 2017
P3, N=370, Completed, Sponsor: Merz Pharmaceuticals GmbH
Trial primary completion date: Sep 2014 --> Dec 2015 Active, not recruiting --> Completed
- Trial completion: Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=20, Completed, Sponsor: Swiss Paraplegic Centre Nottwil
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI) (clinicaltrials.gov) - Dec 28, 2016
P1/2, N=11, Completed, Sponsor: Dr. Gabriel Zeilig
Active, not recruiting --> Completed Not yet recruiting --> Completed | N=20 --> 11 | Trial primary completion date: Dec 2011 --> May 2016
- dronabinol oral / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Cannabis for Spasticity in Multiple Sclerosis (clinicaltrials.gov) - Nov 16, 2016
P1/2, N=42, Terminated, Sponsor: University of California, Davis
Not yet recruiting --> Completed | N=20 --> 11 | Trial primary completion date: Dec 2011 --> May 2016 N=60 --> 42 | Recruiting --> Terminated | Trial primary completion date: Jan 2013 --> Jul 2017; Unable to complete subject recruitment
- Enrollment closed, Trial primary completion date: Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury (clinicaltrials.gov) - Oct 13, 2016
P=N/A, N=20, Active, not recruiting, Sponsor: Swiss Paraplegic Centre Nottwil
N=60 --> 42 | Recruiting --> Terminated | Trial primary completion date: Jan 2013 --> Jul 2017; Unable to complete subject recruitment Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Oct 2016
- |||| baclofen / Generic mfg.
Trial completion, Enrollment change: THE SISTERS STUDY: SISTERS: Spasticity In Stroke Study - Randomized Study (clinicaltrials.gov) - Oct 11, 2016
P4, N=61, Completed, Sponsor: Medtronic International Trading Sarl
Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Oct 2016 Active, not recruiting --> Completed | N=88 --> 61
- Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion: Botulinum Toxin (BOTOX) for Cerebral Palsy (clinicaltrials.gov) - Sep 26, 2016
P2, N=40, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting --> Completed | N=88 --> 61 Withdrawn --> Completed
- ||||||| BTXA (lanbotulinumtoxinA) / Sinopharm
Trial completion, Trial primary completion date: A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi (clinicaltrials.gov) - Sep 26, 2016
P3, N=180, Completed, Sponsor: Lanzhou Institute of Biological Products Co., Ltd
Withdrawn --> Completed Enrolling by invitation --> Completed | Trial primary completion date: Nov 2015 --> Feb 2016
- Xeomin (incobotulinumtoxinA) / Merz Pharma
Trial primary completion date: Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients (clinicaltrials.gov) - Sep 22, 2016
P4, N=27, Active, not recruiting, Sponsor: Multiple Sclerosis Center of Northeastern New York
Enrolling by invitation --> Completed | Trial primary completion date: Nov 2015 --> Feb 2016 Trial primary completion date: Jul 2016 --> Dec 2016
- ||||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Enrollment change: BOTOX (clinicaltrials.gov) - Sep 15, 2016
P3, N=224, Recruiting, Sponsor: Allergan
Trial primary completion date: Jul 2016 --> Dec 2016 N=412 --> 224
- Enrollment change: Developing and Testing a Comprehensive MS Spasticity Management Program (clinicaltrials.gov) - Aug 31, 2016
P2, N=41, Completed, Sponsor: VA Office of Research and Development
N=412 --> 224 N=60 --> 41
- Trial completion: Developing and Testing a Comprehensive MS Spasticity Management Program (clinicaltrials.gov) - Aug 29, 2016
P2, N=60, Completed, Sponsor: VA Office of Research and Development
N=60 --> 41 Active, not recruiting --> Completed
- Sativex (nabiximols) / Jazz
Enrollment change, Trial withdrawal: Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis. (clinicaltrials.gov) - Aug 11, 2016
P3, N=0, Withdrawn, Sponsor: GW Research Ltd
Active, not recruiting --> Completed N=711 --> 0 | Not yet recruiting --> Withdrawn
- || Trial primary completion date: ISPR: Implantable Systems Performance Registry (clinicaltrials.gov) - Jun 27, 2016
P=N/A, N=11500, Recruiting, Sponsor: MedtronicNeuro
N=711 --> 0 | Not yet recruiting --> Withdrawn Trial primary completion date: Apr 2016 --> Oct 2016
- | Xeomin (incobotulinumtoxinA) / Merz Pharma
Enrollment closed: Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients (clinicaltrials.gov) - May 2, 2016
P4, N=27, Active, not recruiting, Sponsor: Multiple Sclerosis Center of Northeastern New York
Trial primary completion date: Apr 2016 --> Oct 2016 Recruiting --> Active, not recruiting
- ||||||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion: BOTOX (clinicaltrials.gov) - Apr 19, 2016
P3, N=468, Completed, Sponsor: Allergan
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment closed, Trial initiation date, Trial primary completion date: Developing and Testing a Comprehensive MS Spasticity Management Program (clinicaltrials.gov) - Mar 28, 2016
P2, N=60, Active, not recruiting, Sponsor: VA Office of Research and Development
Active, not recruiting --> Completed Not yet recruiting --> Active, not recruiting | Initiation date: Jul 2015 --> Oct 2015 | Trial primary completion date: Dec 2015 --> May 2016
- ||||||| Evosyal (prabotulinumtoxin A) / Daewoong Pharma, AEON Biopharma
Trial completion, Trial primary completion date: A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox (clinicaltrials.gov) - Mar 4, 2016
P3, N=197, Completed, Sponsor: Daewoong Pharmaceutical Co. LTD.
Not yet recruiting --> Active, not recruiting | Initiation date: Jul 2015 --> Oct 2015 | Trial primary completion date: Dec 2015 --> May 2016 Recruiting --> Completed | Trial primary completion date: Nov 2013 --> May 2014
- Enrollment change, Trial termination: Energy Costs of Spasticity in Spinal Cord Injury: A Pilot Investigation (clinicaltrials.gov) - Feb 23, 2016
P=N/A, N=20, Terminated, Sponsor: Virginia Commonwealth University
Recruiting --> Completed | Trial primary completion date: Nov 2013 --> May 2014 N=36 --> 20 | Recruiting --> Terminated; Unable to recruit enough participants.
- Trial primary completion date: tDCS(HE): Effects of tDCS on Quadriceps Strength After Stroke (clinicaltrials.gov) - Feb 16, 2016
P=N/A, N=30, Recruiting, Sponsor: Centre d'Investigation Clinique et Technologique 805
N=36 --> 20 | Recruiting --> Terminated; Unable to recruit enough participants. Trial primary completion date: Jan 2016 --> Mar 2017
- ||| baclofen / Generic mfg.
Enrollment closed: THE SISTERS STUDY: SISTERS: Spasticity In Stroke Study - Randomized Study (clinicaltrials.gov) - Feb 10, 2016
P4, N=88, Active, not recruiting, Sponsor: Medtronic International Trading Sarl
Trial primary completion date: Jan 2016 --> Mar 2017 Recruiting --> Active, not recruiting
- baclofen / Generic mfg.
Enrollment change, Trial termination: Long-term Surveillance of the MedStream Programmable Infusion System (clinicaltrials.gov) - Feb 9, 2016
P=N/A, N=2, Terminated, Sponsor: Codman & Shurtleff
Recruiting --> Active, not recruiting N=212 --> 2 | Active, not recruiting --> Terminated; Lack of enrollment
- |||| Xeomin (incobotulinumtoxinA) / Merz Pharma
Trial primary completion date: Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy (clinicaltrials.gov) - Jan 28, 2016
P3, N=370, Active, not recruiting, Sponsor: Merz Pharmaceuticals GmbH
N=212 --> 2 | Active, not recruiting --> Terminated; Lack of enrollment Trial primary completion date: Sep 2016 --> Jan 2017
- ||| Trial completion, Enrollment change: Reliability of an Algorithm to Diagnose Spasticity (clinicaltrials.gov) - Jan 26, 2016
P=N/A, N=72, Completed, Sponsor: Vanderbilt University
Trial primary completion date: Sep 2016 --> Jan 2017 Recruiting --> Completed | N=100 --> 72
- || Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Enrollment closed: ASPIRE: An Adult Spasticity Registry of OnabotulinumtoxinA Treatment (clinicaltrials.gov) - Jan 25, 2016
P=N/A, N=746, Active, not recruiting, Sponsor: Allergan
Recruiting --> Completed | N=100 --> 72 Recruiting --> Active, not recruiting
- Xeomin (incobotulinumtoxinA) / Merz Pharma
Trial primary completion date: Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients (clinicaltrials.gov) - Jan 17, 2016
P4, N=30, Recruiting, Sponsor: Multiple Sclerosis Center of Northeastern New York
Recruiting --> Active, not recruiting Trial primary completion date: Dec 2015 --> Jul 2016
- Myobloc (rimabotulinumtoxin B) / Supernus Pharma, Eisai
Trial completion: Myobloc Atrophy Study (clinicaltrials.gov) - Dec 16, 2015
P4, N=10, Completed, Sponsor: Georgetown University
Trial primary completion date: Dec 2015 --> Jul 2016 Active, not recruiting --> Completed
- Trial completion, Enrollment change: Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients (clinicaltrials.gov) - Nov 10, 2015
P=N/A, N=80, Completed, Sponsor: Changhua Christian Hospital
Active, not recruiting --> Completed Recruiting --> Completed | N=120 --> 80
- Enrollment change, Trial withdrawal: Spasticity Registry Evaluating Epidemiology, Treatment Patterns and Clinical Needs (clinicaltrials.gov) - Nov 5, 2015
P=N/A, N=0, Withdrawn, Sponsor: Allergan
Recruiting --> Completed | N=120 --> 80 N=2000 --> 0 | Suspended --> Withdrawn
- Trial completion: The Effect of Extracorporeal Shock Wave Therapy on Spasticity (clinicaltrials.gov) - Nov 5, 2015
P=N/A, N=60, Completed, Sponsor: Tri-Service General Hospital
N=2000 --> 0 | Suspended --> Withdrawn Recruiting --> Completed
- ||||| Xeomin (incobotulinumtoxinA) / Merz Pharma
Enrollment closed: Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy (clinicaltrials.gov) - Oct 23, 2015
P3, N=360, Active, not recruiting, Sponsor: Merz Pharmaceuticals GmbH
Recruiting --> Completed Recruiting --> Active, not recruiting
- | Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Enrollment change, Trial termination: OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity (clinicaltrials.gov) - Oct 5, 2015
P3, N=53, Terminated, Sponsor: Allergan
Recruiting --> Active, not recruiting N=423 --> 53 | Recruiting --> Terminated
- Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion, Trial primary completion date: Effect of Botox and Vibration on Bone in Children With Cerebral Palsy (clinicaltrials.gov) - Sep 14, 2015
P=N/A, N=29, Completed, Sponsor: University of Delaware
N=423 --> 53 | Recruiting --> Terminated Recruiting --> Completed | Trial primary completion date: Mar 2014 --> Feb 2015
- Trial completion, HEOR, Combination therapy, Cost effectiveness: Efficacy and Cost-effectiveness of Spasticity Treatment With Multifocal TENS (clinicaltrials.gov) - Jul 13, 2015
P=N/A, N=31, Completed, Sponsor: Linkoeping University
Recruiting --> Completed | Trial primary completion date: Mar 2014 --> Feb 2015 Enrolling by invitation --> Completed
- | Trial completion, Enrollment change, Trial primary completion date: Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy (clinicaltrials.gov) - Jul 9, 2015
P=N/A, N=38, Completed, Sponsor: Stanford University
Enrolling by invitation --> Completed Active, not recruiting --> Completed | N=24 --> 38 | Trial primary completion date: Aug 2014 --> Nov 2014
- |||| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial primary completion date: BOTOX (clinicaltrials.gov) - Jun 11, 2015
P3, N=412, Recruiting, Sponsor: Allergan
Active, not recruiting --> Completed | N=24 --> 38 | Trial primary completion date: Aug 2014 --> Nov 2014 Trial primary completion date: Mar 2016 --> Apr 2017