Mesothelioma MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	7	14	21	28	35	42	49	56	63	70



COX2 inhib




Cadherin mod




Calmodulin mod




Capillary permeability mod




DEC-205 agon




DNA excision repair inhib




Dendritic cell activator




Dihydrofolic acid reductase inhib




EPH receptor inhib




Factor X inhib




Fyn inhib




G-CSF stim




G2 checkpoint inhib




GCR agon




GM2 ganglioside inhib




Glutaminase inhib




HSP90 inhib




Histamine H1 receptor antag




IFIH1 mod




IGF-1R inhib




ITK inhib




LMWH inhib




MAPK inhib




MEK2 inhib




MEK2 inhib




MK2 inhib




Osteoclast inhib




Proteasome inhib




RAF kinase inhib




RNA synthesis inhib




Signal transduction pathway inhib




TNFα mod




Thymidine kinase stim




TrkA receptor antag




VP35 protein inhib




Vascular disrupting agent




β-catenin inhib



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