Mental Retardation
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  • ||||||||||  Journal:  Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles. (Pubmed Central) -  Jun 9, 2025   
    In a computational model of this microcircuit, inhibition of simulated fear-active units modulated recruitment of extinction-active units and behavioral variability in freezing, aligning with experimental results. These results suggest that psilocybin enhances behavioral flexibility by recruiting new neuronal populations and suppressing fear-active populations in the retrosplenial cortex.
  • ||||||||||  Journal:  Daily drinking intention-behavior discrepancies are associated with drinking-related consequences. (Pubmed Central) -  Jun 9, 2025   
    Results shed light on the need for a more nuanced operationalization of unplanned drinking behaviors, as current research utilizing a dichotomous lens may not be fully capturing the risky phenomenon. Results suggest that unplanned drinking, particularly related to consuming more drinks than intended, may be a useful indicator of problematic drinking.
  • ||||||||||  Journal:  An analysis of risk factors for child suicide in three centres from 2008 to 2017. (Pubmed Central) -  Jun 9, 2025   
    It does, however, demonstrate that risk factors for child suicide are not uniform among communities and so extrapolation of data from one area to another may not be appropriate. Disturbingly parents/carers were not aware of the decedent's suicidal intent in 84-87.2% of cases.
  • ||||||||||  Journal:  Do Transformers and CNNs Learn Different Concepts of Brain Age? (Pubmed Central) -  Jun 9, 2025   
    Reassuringly, we observed no substantial differences in the structure of brain age predictions across the model architectures. Our findings suggest that the choice of deep learning model architecture does not appear to have a confounding effect on brain age studies.
  • ||||||||||  Journal:  Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment. (Pubmed Central) -  Jun 9, 2025   
    However, institutions without navigation equipment are unable to utilize these function-specific targets. Therefore, we have developed a non-navigated localization method for function-specific targets, specifically designed to define and localize rTMS targets in the post-stroke ipsilateral hemisphere, addressing the challenges faced by institutions lacking navigation equipment when applying function-specific targeted rTMS.
  • ||||||||||  Journal:  The role of clinicians in the looping effect: epistemic injustices and looping breaks. (Pubmed Central) -  Jun 9, 2025   
    We identify epistemic injustices as critical factors that can lead to looping breaks at both levels, thus affecting the stability and validity of psychiatric diagnoses. Our findings underscore the importance of an epistemic approach to the looping effect, emphasizing both knowledge validity and justice in clinician-patient relationships and among clinicians themselves.
  • ||||||||||  Review, Journal:  Idiopathic Hypersomnia: Recognition and Management in Psychiatric Practice. (Pubmed Central) -  Jun 9, 2025   
    Psychiatric clinicians are more likely to encounter patients with idiopathic hypersomnia than would be expected given its overall prevalence due to increased rate of psychiatric symptom comorbidity in this population. Recognizing and managing idiopathic hypersomnia for individuals with psychiatric conditions may lead to improvements in treatment outcome for patients.
  • ||||||||||  ketamine / Generic mfg.
    Journal:  Outpatient Ketamine Prescribing Practices in Psychiatry in the United States: A Nationwide Survey Study. (Pubmed Central) -  Jun 9, 2025   
    There is significant variability in ketamine treatment in the community including indications for therapy, duration of treatment courses, formulation of ketamine prescribed, and setting of use. There is a need for increased oversight and more specific practice guidelines to ensure ketamine is being used safely, appropriately, and effectively.
  • ||||||||||  Journal:  Development of survey measures of uncontrolled vaping and vaping restraint. (Pubmed Central) -  Jun 9, 2025   
    By capturing these dimensions, the scales offer insights beyond traditional nicotine dependence measures, supporting research and interventions tailored to vaping-specific challenges. The findings highlight the importance of addressing uncontrolled vaping through regulatory and clinical efforts, informing strategies to reduce excessive vaping, and promoting self-regulation among e-cigarette users.
  • ||||||||||  Journal:  REM sleep microstructure alterations in REM sleep behavior disorder: beyond muscle tone. (Pubmed Central) -  Jun 9, 2025   
    The findings highlight the importance of addressing uncontrolled vaping through regulatory and clinical efforts, informing strategies to reduce excessive vaping, and promoting self-regulation among e-cigarette users. These results reinforce the hypothesis that REM sleep dysregulation in RBD extends to REM-specific electrophysiological features beyond loss of muscle atonia and dream enactments.
  • ||||||||||  Journal:  Case Report: Special recoveries from major mental illness in childhood: a case series. (Pubmed Central) -  Jun 9, 2025   
    Treatments included antimicrobials, nutraceuticals, probiotics, and dietary changes. Converging lines of research highlight the importance of considering neuroinflammatory conditions in the differential diagnosis of children with treatment-resistant neuropsychiatric symptoms.
  • ||||||||||  Journal:  Aural myiasis in a healthy adult laborer from Nepal: a case report. (Pubmed Central) -  Jun 9, 2025   
    Preventive measures include improving hygiene and addressing predisposing factors such as chronic ear conditions, socioeconomic barriers, and environmental exposures. Early eradication of larvae is vital to avoid severe outcomes, emphasizing the need for awareness among clinicians and the general population individuals.
  • ||||||||||  Journal:  Bardet-Biedl syndrome in a Syrian adolescent: a rare case report. (Pubmed Central) -  Jun 9, 2025   
    The findings underscore the necessity for individualized diagnostic approaches and comprehensive management strategies in patients with limited access to genetic testing. By documenting this case, we contribute to the growing body of literature on BBS, particularly in the Syrian context, highlighting the need for increased awareness and research into this challenging disorder.
  • ||||||||||  Journal:  Electroconvulsive Therapy for Malignant Catatonia: A Case Report in the Intensive Care Unit. (Pubmed Central) -  Jun 9, 2025   
    Electroconvulsive therapy (ECT) may be considered in certain cases, particularly when standard treatments fail, though its use in ICU settings is rare due to concerns about patient stability and procedural risk. We present the case of a 43-year-old male, admitted for a manic episode, who was transferred to the ICU following a cardiorespiratory arrest and subsequently treated with ECT for malignant catatonia.
  • ||||||||||  dexmedetomidine / Generic mfg.
    Retrospective data, Journal:  Effects of Dexmedetomidine on Delirium in Trauma Intensive Care Unit (ICU) Patients: A Retrospective Cohort Study. (Pubmed Central) -  Jun 9, 2025   
    The findings align with the current body of research, highlighting that pre-existing psychiatric conditions and benzodiazepine use are recognized risk factors for delirium in the trauma ICU population. Nevertheless, dexmedetomidine administration was not found to significantly influence the likelihood of developing delirium in these patients.
  • ||||||||||  Journal:  Organ donation after medically assisted death on psychiatric grounds: an ethical analysis. (Pubmed Central) -  Jun 9, 2025   
    Careful assessment of the patient's decision-making capacity and the absence of external pressure are needed to avoid the stigmatization of individuals with psychiatric conditions. Further research to better understand the possible interplay between psychiatric disorders and decision-making capacity in the context of organ donation after MAID is recommended.
  • ||||||||||  Journal:  Isolated Mega Cisterna Magna: A Preliminary Study from Eastern Iran. (Pubmed Central) -  Jun 9, 2025   
    Conclusion ?MCM appears to be a normal variation in the general population with no clinical significance. Despite the small sample size, the current study can provide a foundation for further studies to investigate the correlation of isolated MCM with different aspects of cognitive functions and its potential clinical relevance.
  • ||||||||||  Enrollment open, Trial primary completion date:  Evaluation of a Digital Pre-therapy Patient Education Program (StartHjelp) in Outpatient Mental Health Care (clinicaltrials.gov) -  Jun 9, 2025   
    P=N/A,  N=170, Recruiting, 
    Our findings highlight the potential of small-molecule chaperones as interventions for ameliorating protein misfolding and functional deficits in hGAT-1-associated pathologies. Not yet recruiting --> Recruiting | Trial primary completion date: Dec 2028 --> Dec 2026