Mastocytosis MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	2	4	6	8	10	12	14	16	18	20



CD20 inhib




c-KIT inhib




PDGFR inhib




c-KIT inhib




AKT inhib




CD20 inhib




Purinergic receptor P1 agon




VEGF inhib




Fyn inhib




IFNα stim




IMPDH inhib




Immunosuppressant




Tubulin polymerization promoter




mTOR inhib




AKT inhib




Aurora kinase A inhib




Bcl2 inhib




Bcl2 inhib




CD20 inhib




CTLA4 inhib




CXCR4 antag




Calcineurin inhib




DGAT-1 inhib




FAK inhib




FGFR3 inhib




HIF-1 inhib




HIF-1 inhib




Hematopoietic stem cell mobilizer




IGF-1R inhib




IL-2 stim




IL-2 stim




IgE inhib




Macrophage inhib




Mast cell inhib




PI3K inhib




PKC inhib




RAS inhib




SARS-CoV-2 3CL pro inhib




STAT3 inhib




TNF inhib



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