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306 Companies |
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474 Products |
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474 Products |
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223 Mechanisms of Action |
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25 Trials |
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4911 News |
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- || GS-6620 / Gilead
Enrollment change: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Na (clinicaltrials.gov) - Sep 21, 2011
P1, N=90, Completed, Sponsor: Gilead Sciences
N=60 --> 90
- | GSK 2336805 / J&J
New P2 trial, Combination therapy: Safety, Antiviral Activity, and Pharmacokinetics of GSK2336805 With Peginterferon and Ribavirin in Chronic Hepatitis C Subjects (clinicaltrials.gov) - Sep 21, 2011
P2, N=17, Completed, Sponsor: GlaxoSmithKline
- ||| trebananib (AMG 386) / Amgen
Enrollment closed, IO biomarker, Metastases: A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer (clinicaltrials.gov) - Sep 21, 2011
P2, N=60, Active, not recruiting, Sponsor: Amgen
N=60 --> 90 Recruiting --> Active, not recruiting
- Trial completion: A2ALL-1: Adult-to-Adult Living Donor Liver Transplantation Study (clinicaltrials.gov) - Sep 21, 2011
P=N/A, N=2470, Completed, Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- |||| CC-700C / TCM Biotech
Trial completion: The Effects of Adding TCM-700C on the Standard Combination Treatment for Patients With Genotype 1 Hepatitis C Infection (clinicaltrials.gov) - Sep 20, 2011
P2, N=84, Completed, Sponsor: TCM Biotech International Corp.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Magnetic Resonance Elastography for Assessment of Liver Fibrosis (MK-0000-132)(COMPLETED) (clinicaltrials.gov) - Sep 20, 2011
P1, N=10, Completed, Sponsor: Merck Sharp & Dohme Corp.
Active, not recruiting --> Completed N=20 --> 10
- Enrollment change: Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C (clinicaltrials.gov) - Sep 20, 2011
P=N/A, N=24, Completed, Sponsor: University Health Network, Toronto
N=20 --> 10 N=52 --> 24
- | Trial completion, Surgery: Comparison of the Hemostatic Patch to Fibrin Sealant (TachoSil (clinicaltrials.gov) - Sep 20, 2011
P=N/A, N=50, Completed, Sponsor: Covidien
N=52 --> 24 Recruiting --> Completed
- Trial completion: Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C (clinicaltrials.gov) - Sep 20, 2011
P=N/A, N=24, Completed, Sponsor: University Health Network, Toronto
Recruiting --> Completed Recruiting --> Completed
- ViraferonPeg (peginterferon-?-2b) / Merck (MSD)
Biomarker, Trial termination: RE-CHUT: Relapse Rate in Hepatitis C Patients Treated With Peginterferon Alfa-2b Plus Ribavirin in Common Clinical Practice in France (P05484)(Completed) (clinicaltrials.gov) - Sep 19, 2011
P=N/A, N=97, Terminated, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed Recruiting --> Terminated; Low enrollment
- ViraferonPeg (peginterferon-?-2b) / Merck (MSD)
Biomarker, Enrollment change: RE-CHUT: Relapse Rate in Hepatitis C Patients Treated With Peginterferon Alfa-2b Plus Ribavirin in Common Clinical Practice in France (P05484)(Completed) (clinicaltrials.gov) - Sep 19, 2011
P=N/A, N=97, Terminated, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Terminated; Low enrollment N=597 --> 97
- | Cyramza (ramucirumab) / Eli Lilly
Trial completion, Monotherapy: Study of IMC-1121B (Ramucirumab) in Participants With Liver Cancer Who Have Not Previously Been Treated With Chemotherapy (clinicaltrials.gov) - Sep 19, 2011
P2, N=42, Completed, Sponsor: Eli Lilly and Company
N=597 --> 97 Active, not recruiting --> Completed
- Trial completion: Resection for Multiple Hepatocellular Carcinomas (HCC) (clinicaltrials.gov) - Sep 18, 2011
P=N/A, N=87, Completed, Sponsor: University of Milan
Active, not recruiting --> Completed Not yet recruiting --> Completed
- Pegasys (pegylated interferon α -2a) / Roche
Trial completion, Monotherapy: ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B (clinicaltrials.gov) - Sep 18, 2011
P3, N=10, Completed, Sponsor: Hoffmann-La Roche
Not yet recruiting --> Completed Active, not recruiting --> Completed
- |||| Pegasys (pegylated interferon ? -2a) / Roche
Trial completion: POTENTE Study: A Study of Early Virological Response in Naive Patients With Chronic Hepatitis C, Genotype 2 or 3, Treated With PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Copegus (Ribavirin). (clinicaltrials.gov) - Sep 18, 2011
P4, N=266, Completed, Sponsor: Hoffmann-La Roche
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| entecavir / Generic mfg.
New P2 trial, Monotherapy: Safety and Antiviral Activity of Entecavir in Participants With Chronic Hepatitis B Following Monotherapy in Other Entecavir Trials (clinicaltrials.gov) - Sep 15, 2011
P2, N=1053, Completed, Sponsor: Bristol-Myers Squibb
- ||||||| Quinvaxem (diphtheria, Tetanus, whole-cell pertussis- HiB - HepB) / GSK
Trial completion: Study of Quinvaxem for Vaccination Against Diphtheria, Pertussis, Tetanus, Hepatitis B and Diseases Caused by Haemophilus Influenzae Type B (clinicaltrials.gov) - Sep 14, 2011
P3, N=131, Completed, Sponsor: Crucell Holland BV
Active, not recruiting --> Completed Active, not recruiting --> Completed
- |||| Havrix (hepatitis A vaccine, inactivated) / GSK
Trial completion: A Study to Evaluate the Safety and Immunogenicity of the Hepatitis A Virus Vaccine HAVpur in Healthy Young Children (clinicaltrials.gov) - Sep 14, 2011
P4, N=251, Completed, Sponsor: Crucell Holland BV
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| vedroprevir (GS 9451) / Gilead, tegobuvir (GS 9190) / Gilead
New P2 trial: GS-5885, GS-9451, Tegobuvir and Ribovirin in Treatment-Experienced Subjects With Chronic Genotype 1a Or 1b Hepatitis C Virus (HCV) Infection (clinicaltrials.gov) - Sep 14, 2011
P2, N=170, Completed, Sponsor: Gilead Sciences
- ||||| GS-0938 / Gilead
New P2 trial: QUANTUM: Safety Study of Regimens of Sofosbuvir, GS-0938, and Ribavirin in Patients With Chronic Hepatitis C Infection (clinicaltrials.gov) - Sep 13, 2011
P2, N=239, Completed, Sponsor: Gilead Sciences
- | tacrolimus intravenous / Generic mfg., cyclosporin A microemulsion / Generic mfg., mycophenolate sodium / Generic mfg.
Biomarker, Trial completion: Assessment of Biomarkers for Recurrent HCV Infection Post-liver Transplantation (clinicaltrials.gov) - Sep 13, 2011
P=N/A, N=40, Completed, Sponsor: University of Alberta
Active, not recruiting --> Completed Active, not recruiting --> Completed
- TheraSphere (yttrium 90 microspheres) / Boston Scientific
New P1 trial: Study of Gemcitabine With TheraSphere (clinicaltrials.gov) - Sep 13, 2011
P1, N=24, Recruiting, Sponsor: Hyun Kevin Kim
- pioglitazone / Generic mfg.
Enrollment closed: PEGLIST C: Pioglitazone vs. Placebo in Association With Pegylated Interferon and Ribavirin in HCV Patients With Insulin Resistance (clinicaltrials.gov) - Sep 13, 2011
P3, N=40, Active, not recruiting, Sponsor: French National Agency for Research on AIDS and Viral Hepatitis
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion: Heliac: Inflammation, Immune Activation and Portal Hypertension in Alcoholic Hepatitis (clinicaltrials.gov) - Sep 13, 2011
P=N/A, N=60, Completed, Sponsor: University of Aarhus
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion: A Clinical Research Study Designed To Determine If Treatment of Hepatitis C With Milk Thistle is More Effective Than No Treatment In Patients Infected With Both HIV And Hepatitis C (clinicaltrials.gov) - Sep 13, 2011
P1/2, N=40, Completed, Sponsor: Henry Sacks
Recruiting --> Completed Active, not recruiting --> Completed
- | mycophenolate mofetil / Generic mfg.
Enrollment change: Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparative Study Between Tacrolimus + MMF and Tacrolimus + Steroid (clinicaltrials.gov) - Sep 12, 2011
P3, N=79, Completed, Sponsor: Translational Research Informatics Center, Kobe, Hyogo, Japan
Active, not recruiting --> Completed N=120 --> 79
- ||| Clinical: Risk of Acute Liver Injury in Users of Antimicrobials (clinicaltrials.gov) - Sep 12, 2011
P=N/A, N=1299056, Completed, Sponsor: Bayer
- | mycophenolate mofetil / Generic mfg.
Trial completion: Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparative Study Between Tacrolimus + MMF and Tacrolimus + Steroid (clinicaltrials.gov) - Sep 12, 2011
P3, N=79, Completed, Sponsor: Translational Research Informatics Center, Kobe, Hyogo, Japan
N=120 --> 79 Active, not recruiting --> Completed
- CTS-1027 / Histogen
Enrollment change: Standard of Care (SOC) With or Without CTS-1027 in Hepatitis C (HCV) Null-Responders (clinicaltrials.gov) - Sep 12, 2011
P2, N=114, Terminated, Sponsor: Conatus Pharmaceuticals Inc.
Active, not recruiting --> Completed N=260 --> 114
- || New P3 trial: Response to Pegylated Interferon and Ribavirin in Chinese Patients With Chronic Hepatitis C Genotypes 1 Versus 2/3 Versus 6 (clinicaltrials.gov) - Sep 12, 2011
P3, N=535, Active, not recruiting, Sponsor: Third Affiliated Hospital, Sun Yat-Sen University
- Trial withdrawal: Safety and Efficacy of the Extracorporeal Liver Assist Device (ELAD®) In Patients With Fulminant Hepatic Failure (FHF) (clinicaltrials.gov) - Sep 11, 2011
P2, N=0, Withdrawn, Sponsor: Vital Therapies, Inc.
N=260 --> 114 Active, not recruiting --> Withdrawn
- ribavirin / Generic mfg.
New P1/2 trial, Combination therapy: Safety and Biological Activity of InfraDure Biopump Secreting Sustained Interferon in HCV Patients (clinicaltrials.gov) - Sep 11, 2011
P1/2, N=3, Terminated, Sponsor: Medgenics Medical Israel Ltd.
- Trial completion: Analysis of Trends Over Time of Hepatitis Related Incidence in Panama (clinicaltrials.gov) - Sep 8, 2011
P=N/A, N=1, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Withdrawn Recruiting --> Completed
- | Sivextro (tedizolid) / Merck (MSD), Nabriva Therap
New P1 trial: A PK and Safety Study in Subjects With Hepatic Impairment (clinicaltrials.gov) - Sep 8, 2011
P1, N=32, Completed, Sponsor: Trius Therapeutics, Inc.
- | Olysio (simeprevir) / J&J, Medivir
Trial completion: TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435 (clinicaltrials.gov) - Sep 8, 2011
P1, N=23, Completed, Sponsor: Tibotec Pharmaceuticals, Ireland
Recruiting --> Completed Recruiting --> Completed
- Campath (alemtuzumab) / Sanofi
Trial completion: TILT: Immune System Suppression With Alemtuzumab and Tacrolimus in Liver Transplantation Patients (clinicaltrials.gov) - Sep 7, 2011
P2, N=27, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Active, not recruiting --> Completed
- everolimus / Generic mfg.
Trial termination: REVERT: Efficacy of Everolimus as Inhibitor of Fibrosis Progression in Liver Transplant Patients With Recurrence of Hepatitis C Viral Infection (clinicaltrials.gov) - Sep 7, 2011
P2, N=43, Terminated, Sponsor: Novartis Pharmaceuticals
Active, not recruiting --> Completed Recruiting --> Terminated
- MK-4074 / Merck (MSD)
New P1 trial: Study of Changes in Hepatic Fat Following Administration of MK-4074 and Pioglitazone Hydrochloride (MK-4074-008) (clinicaltrials.gov) - Sep 7, 2011
P1, N=31, Completed, Sponsor: Merck
- EB06 / Light Chain Biosci, Edesa Biotech
New P2 trial: Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (clinicaltrials.gov) - Sep 6, 2011
P2, N=0, Terminated, Sponsor: NovImmune SA
- | cisplatin / Generic mfg.
New P2 trial: RTANDTACE: Efficacy of Radiation Therapy and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma (HCC) (clinicaltrials.gov) - Sep 6, 2011
P2, N=55, Not yet recruiting, Sponsor: Asan Medical Center
- Enrollment change, Surgery: Impact of Microparticles on Postoperative Complications in Surgical Patients (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=108, Completed, Sponsor: University of Bern
Recruiting --> Terminated N=14 --> 108
- Trial completion, Surgery: Impact of Microparticles on Postoperative Complications in Surgical Patients (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=108, Completed, Sponsor: University of Bern
N=14 --> 108 Recruiting --> Completed
- ribavirin / Generic mfg.
Trial completion: CIRES: Study Investigating Immunological Effects of Treatment for Chronic Hepatitis C Patients. (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=27, Completed, Sponsor: Foundation for Liver Research
Recruiting --> Completed Active, not recruiting --> Completed
- Intron A (interferon α-2b) / Merck (MSD), Biogen
New P1/2 trial: Safety and Efficacy of Sustained Interferon Alfa 2b (INF) Therapy of Relapsing Hepatitis C (HCV) Patients Using InfraDure Biopump (clinicaltrials.gov) - Sep 3, 2011
P1/2, N=0, Withdrawn, Sponsor: Medgenics Medical Israel Ltd.
- Post-transplantation: Outcomes in Hepatitis C After Living Donor Liver Transplantation in Association With Interleukin 28 B (clinicaltrials.gov) - Sep 1, 2011
P=N/A, N=40, Recruiting, Sponsor: Henry Ford Health System
- ||||||| Promacta (eltrombopag) / Novartis
Trial completion: Eltrombopag To Initiate And Maintain Interferon Antiviral Treatment To Benefit Subjects With Hepatitis C Liver Disease (clinicaltrials.gov) - Sep 1, 2011
P3, N=759, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | CTS-1027 / Histogen
Trial termination: Standard of Care (SOC) With or Without CTS-1027 in Hepatitis C (HCV) Null-Responders (clinicaltrials.gov) - Sep 1, 2011
P2, N=114, Terminated, Sponsor: Conatus Pharmaceuticals Inc.
Active, not recruiting --> Completed Active, not recruiting --> Terminated; Risk-benefit ratio
- Trial termination: The Role of Fluorothymidine Positron Emission Tomography (FLT-PET) in Proliferation of Colorectal Liver Metastases (clinicaltrials.gov) - Sep 1, 2011
P1/2, N=80, Terminated, Sponsor: Radboud University
Active, not recruiting --> Terminated; Risk-benefit ratio Recruiting --> Terminated; no accrual achieved
- pioglitazone / Generic mfg.
Enrollment change: University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial) (clinicaltrials.gov) - Aug 31, 2011
P4, N=90, Active, not recruiting, Sponsor: The University of Texas Health Science Center at San Antonio
Recruiting --> Terminated; no accrual achieved N=120 --> 90
- ||||| New P2 trial: Study of pegInterferon Alfa-2a, Ribavirin, and Daclatasvir (BMS-790052) With or Without BMS-650032 for Participants in Some Hepatitis C Virus Trials (clinicaltrials.gov) - Aug 31, 2011
P2, N=300, Recruiting, Sponsor: Bristol-Myers Squibb