- |||||||||| Biomarker, Trial completion, Trial completion date, Trial primary completion date: Nonalcoholic Fatty Liver Disease in Taiwanese Children (clinicaltrials.gov) - Apr 21, 2019
P=N/A, N=614, Completed, Active, not recruiting --> Completed | N=64 --> 24 | Trial completion date: Jul 2019 --> Jul 2018 Recruiting --> Completed | Trial completion date: Dec 2019 --> Dec 2018 | Trial primary completion date: Dec 2017 --> Dec 2018
- |||||||||| Enrollment change, Trial termination, Surgery: IOUS: Freehand Ultrasound Elasticity Imaging in Liver Surgery (clinicaltrials.gov) - Apr 20, 2019
P=N/A, N=15, Terminated, Recruiting --> Completed | Trial completion date: Dec 2019 --> Dec 2018 | Trial primary completion date: Dec 2017 --> Dec 2018 N=40 --> 15 | Recruiting --> Terminated; low accrual
- |||||||||| JNJ-47910382 / J&J
Enrollment change, Trial termination: A Study of the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of JNJ-47910382 at Different Doses and Dose Regimens in Asian Genotype-1, Chronic, HCV-Infected Patients (clinicaltrials.gov) - Apr 20, 2019 P1, N=8, Terminated, N=140 --> 7 | Active, not recruiting --> Terminated; insufficient recruitment N=18 --> 8 | Recruiting --> Terminated; Because of many competing trials using the same mechanism of action, but being further advanced in development
- |||||||||| Biomarker, Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Development of a Novel Biomarker for Liver Fibrosis (clinicaltrials.gov) - Apr 17, 2019
P=N/A, N=25, Completed, N=18 --> 8 | Recruiting --> Terminated; Because of many competing trials using the same mechanism of action, but being further advanced in development Recruiting --> Completed | N=125 --> 25 | Trial completion date: Mar 2018 --> Feb 2019 | Trial primary completion date: Mar 2018 --> Jan 2019
- |||||||||| Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury (clinicaltrials.gov) - Mar 11, 2019
P=N/A, N=28, Completed, Recruiting --> Completed | N=125 --> 25 | Trial completion date: Mar 2018 --> Feb 2019 | Trial primary completion date: Mar 2018 --> Jan 2019 Recruiting --> Completed | N=75 --> 28 | Trial completion date: Apr 2019 --> Jul 2018 | Trial primary completion date: Apr 2019 --> Jul 2018
- |||||||||| Lipotecan (TLC388) / Taiwan Liposome Company
Trial termination, Metastases: Efficacy and Safety Study of TLC388 to Advanced Hepatocellular Carcinoma (clinicaltrials.gov) - Feb 26, 2019 P2, N=29, Terminated, Active, not recruiting --> Completed | Trial primary completion date: Jan 2017 --> Apr 2017 Completed --> Terminated; Current study design couldn't support futher development on this indication
- |||||||||| Omegaven (omega-3 long-chain polyunsaturated fatty acids) / Fresenius Kabi
Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Use of Omegaven Fish Oil Emulsion for Parenteral Nutrition Associated Liver Disease in Infants and Children (clinicaltrials.gov) - Feb 16, 2019 P3, N=36, Completed, Recruiting --> Completed | Trial completion date: Aug 2019 --> Feb 2019 Recruiting --> Completed | N=10 --> 36 | Trial completion date: Aug 2025 --> Jan 2019 | Trial primary completion date: Aug 2020 --> Nov 2018
- |||||||||| midodrine hydrochloride / Generic mfg.
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date: Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure (clinicaltrials.gov) - Feb 16, 2019 P2, N=0, Withdrawn, Recruiting --> Completed | N=10 --> 36 | Trial completion date: Aug 2025 --> Jan 2019 | Trial primary completion date: Aug 2020 --> Nov 2018 N=15 --> 0 | Trial completion date: Aug 2016 --> Aug 2017 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2014 --> Jul 2017
- |||||||||| Biomarker, Enrollment change, Trial termination: Protein Biomarker in Hepatocellular Carcinoma (clinicaltrials.gov) - Feb 16, 2019
P=N/A, N=211, Terminated, N=15 --> 0 | Trial completion date: Aug 2016 --> Aug 2017 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2014 --> Jul 2017 N=1050 --> 211 | Suspended --> Terminated; Loss of funding due to difficulty with recruitment and participant retention.
- |||||||||| tenofovir disoproxil fumarate / Generic mfg.
Trial completion, Trial primary completion date: EMRP36100N: Tenofovir in Chronic Hepatitis B With Mild ALT Elevation (clinicaltrials.gov) - Feb 12, 2019 P4, N=160, Completed, N=1050 --> 211 | Suspended --> Terminated; Loss of funding due to difficulty with recruitment and participant retention. Active, not recruiting --> Completed | Trial primary completion date: Jan 2018 --> Nov 2018
- |||||||||| folate-tubulysin (EC1456) / Novartis
Trial completion, Trial completion date, Metastases: Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors (clinicaltrials.gov) - Feb 7, 2019 P1, N=93, Completed, Recruiting --> Completed | Trial completion date: Dec 2019 --> May 2018 | Trial primary completion date: Dec 2018 --> May 2018 Active, not recruiting --> Completed | Trial completion date: Jul 2018 --> Apr 2018
- |||||||||| Trial completion: Effect of Dietary Macronutrient Composition (clinicaltrials.gov) - Feb 6, 2019
P=N/A, N=24, Completed, Active, not recruiting --> Completed | Trial completion date: Jul 2018 --> Apr 2018 Active, not recruiting --> Completed
- |||||||||| Vaqta (hepatitis A vaccine, inactivated) / Merck (MSD), Varivax (varicella virus vaccine live) / Merck (MSD), ProQuad (measles, mumps, rubella and varicella virus vaccine live) / Merck (MSD)
Phase classification: Hepatitis A Vaccine, Inactivated and Measles, Mumps, Rubella and Varicella Virus Vaccine Live Safety Study (V251-066)(COMPLETED) (clinicaltrials.gov) - Feb 4, 2019 P4, N=1800, Completed, Enrolling by invitation --> Completed Phase classification: P3 --> P4
- |||||||||| Kanuma (sebelipase alfa) / AstraZeneca
Trial completion, Trial primary completion date: VITAL: Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency (clinicaltrials.gov) - Jan 30, 2019 P2/3, N=9, Completed, Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Jan 2018
- |||||||||| Euvax B (recombinant hepatitis B vaccine) / LG Chem
Trial completion, Trial completion date, Trial primary completion date: Strategies for the Prevention of Hepatitis B Among HIV Infected Patients in Uganda (clinicaltrials.gov) - Jan 25, 2019 P4, N=132, Completed, Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Jan 2018 Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Apr 2017 | Trial primary completion date: Jul 2018 --> Apr 2017
- |||||||||| Enrollment change, Trial withdrawal, Trial primary completion date: Hepatocyte Transplantation for Acute Decompensated Liver Failure (clinicaltrials.gov) - Jan 23, 2019
P1, N=0, Withdrawn, Trial completion date: Sep 2015 --> Sep 2018 N=15 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Oct 2018 --> Jan 2019
- |||||||||| TG 4040 / Transgene
Enrollment change: TG4040 in Patients With Chronic HCV (clinicaltrials.gov) - Jan 23, 2019 P1, N=0, Withdrawn, N=15 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Oct 2018 --> Jan 2019 N=85 --> 0
- |||||||||| veliparib (ABT-888) / AbbVie
Trial termination, Combination therapy, BRCA Biomarker, PARP Biomarker, Metastases: Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancer (clinicaltrials.gov) - Jan 3, 2019 P1, N=44, Terminated, Recruiting --> Completed | N=26 --> 9 | Trial primary completion date: Jun 2019 --> Jan 2018 Recruiting --> Terminated
- |||||||||| paracetamol / Generic mfg., methylprednisolone sodium succinate / Generic mfg.
Trial completion, Enrollment change: A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation (clinicaltrials.gov) - Dec 5, 2018 P=N/A, N=177, Completed, Recruiting --> Completed | N=262 --> 79 | Trial completion date: Jan 2016 --> Sep 2018 | Trial primary completion date: Sep 2015 --> Sep 2018 Active, not recruiting --> Completed | N=3000 --> 177
- |||||||||| Trial termination: The Role of Non-Alcoholic Fatty Liver Disease in Gestational Diabetes (clinicaltrials.gov) - Nov 8, 2018
P=N/A, N=126, Terminated, Recruiting --> Completed | Trial completion date: Jun 2016 --> Nov 2018 | Trial primary completion date: Jun 2016 --> Feb 2018 Active, not recruiting --> Terminated; Expired with the IRB
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