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15 Mechanisms of Action |
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- Enrollment closed, Trial primary completion date: SHOCK-COOL: Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction (clinicaltrials.gov) - Nov 15, 2015
P=N/A, N=40, Active, not recruiting, Sponsor: University of Leipzig
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Nov 2015
- Trial primary completion date: Therapeutic Hypothermia After Cardiac Arrest in Non Shockable Rhythm (clinicaltrials.gov) - Nov 11, 2015
P=N/A, N=584, Recruiting, Sponsor: Centre Hospitalier Departemental Vendee
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Nov 2015 Trial primary completion date: Jan 2016 --> Jan 2017
- New trial: Amino Acid Infusion in Mothers Before and During Cesarean Delivery (clinicaltrials.gov) - Oct 23, 2015
P=N/A, N=76, Recruiting, Sponsor: B.P. Koirala Institute of Health Sciences
- midodrine hydrochloride / Generic mfg.
Trial completion: Body Temperature in Persons With Tetraplegia When Exposed to Cold (clinicaltrials.gov) - Oct 20, 2015
P4, N=30, Completed, Sponsor: James J. Peters Veterans Affairs Medical Center
Trial primary completion date: Jan 2016 --> Jan 2017 Active, not recruiting --> Completed
- | Enrollment closed, Trial primary completion date: HYBERNATUS: Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care (clinicaltrials.gov) - Sep 25, 2015
P3, N=270, Active, not recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Sep 2016
- Trial primary completion date: Kangaroo Mother Care to Prevent Hypothermia in Preterm Infants (clinicaltrials.gov) - Sep 25, 2015
P=N/A, N=220, Recruiting, Sponsor: University of Alabama at Birmingham
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Sep 2016 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial primary completion date: CARBOXHYD: Cardiac ARrest : Brain OXymetry Depending on HYpothermia Depth (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=70, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nice
Trial primary completion date: Dec 2015 --> Dec 2016 Trial primary completion date: Sep 2014 --> Sep 2015
- heparin sodium injection / Generic mfg.
New trial, Surgery: The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized CardioLink-3 Trial (clinicaltrials.gov) - Sep 18, 2015
P=N/A, N=110, Recruiting, Sponsor: St. Michael's Hospital, Toronto
- New trial: Clinical Trial of a New Rectum Cooling System on Patients of Hypoxic-ischemic Brain Damage (clinicaltrials.gov) - Sep 9, 2015
P=N/A, N=60, Recruiting, Sponsor: Children's Hospital of Chongqing Medical University
- New trial: Mild Hypothermia During Intracranial Aneurysm Clipping (clinicaltrials.gov) - Sep 9, 2015
P=N/A, N=44, Not yet recruiting, Sponsor: University Hospital Hradec Kralove
- Enrollment closed: Kangaroo Mother Care to Prevent Hypothermia in Term Infants (clinicaltrials.gov) - Sep 3, 2015
P=N/A, N=400, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Trial primary completion date: Sep 2014 --> Sep 2015 Recruiting --> Active, not recruiting
- Trial completion: SHIVER: Study of Heat and Intravenous Fluids for Exogenous Rewarming (clinicaltrials.gov) - Aug 26, 2015
P=N/A, N=8, Completed, Sponsor: Stanford University
Recruiting --> Active, not recruiting Not yet recruiting --> Completed
- Trial completion, Trial primary completion date: PremaTOR: Premature Termination of Resuscitation in Survivors of Cardiac Arrest (clinicaltrials.gov) - Aug 17, 2015
P=N/A, N=560, Completed, Sponsor: Sunnybrook Health Sciences Centre
Not yet recruiting --> Completed Enrolling by invitation --> Completed | Trial primary completion date: Oct 2013 --> Jun 2014
- New trial, Surgery: Preoperative Warming Prevents Postoperative Hypothermia in Laparoscopic Gynecologic Surgery. A Randomized Control Trial (clinicaltrials.gov) - Aug 10, 2015
P=N/A, N=42, Completed, Sponsor: Toronto East General Hospital
- New trial, Surgery: Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery (clinicaltrials.gov) - Aug 3, 2015
P=N/A, N=80, Recruiting, Sponsor: Hongwen Ji
- Trial completion, Surgery: Comparison of Forced Air and Conductive Patient Heating Systems During Ambulatory Surgeries (clinicaltrials.gov) - Jul 24, 2015
P=N/A, N=50, Completed, Sponsor: Fox Valley Orthopedic Institute
Enrolling by invitation --> Completed | Trial primary completion date: Oct 2013 --> Jun 2014 Recruiting --> Completed
- | Trial completion: Measurement of Core Temperatures During Therapeutic Hypothermia (clinicaltrials.gov) - Jul 21, 2015
P=N/A, N=20, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed Recruiting --> Completed
- || New P2/3 trial: Hemen: Hypothermia Enhanced by Magnesium Sulphate (clinicaltrials.gov) - Jul 16, 2015
P2/3, N=75, Completed, Sponsor: Polish Mother Memorial Hospital Research Institute
- Enrollment open, Surgery: Comparison of Forced Air and Conductive Patient Heating Systems During Ambulatory Surgeries (clinicaltrials.gov) - Jul 10, 2015
P=N/A, N=50, Recruiting, Sponsor: Fox Valley Orthopedic Institute
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion, Trial primary completion date: Observational Examination of Thermoregulation in Total Joint Arthroplasty (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=110, Completed, Sponsor: Medical University of South Carolina
Not yet recruiting --> Recruiting Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jun 2015
- midodrine hydrochloride / Generic mfg.
Trial primary completion date: Body Temperature in Persons With Tetraplegia When Exposed to Cold (clinicaltrials.gov) - Jun 25, 2015
P4, N=30, Active, not recruiting, Sponsor: James J. Peters Veterans Affairs Medical Center
Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jun 2015 Trial primary completion date: Apr 2015 --> Aug 2015
- || Trial primary completion date: The Cardiac Effects of Prolonged Hypothermia After Cardiac Arrest (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=100, Recruiting, Sponsor: University of Aarhus
Trial primary completion date: Apr 2015 --> Aug 2015 Trial primary completion date: Mar 2015 --> Jul 2015
- Trial primary completion date: Hypothermia Following Acute Spinal Cord Injury (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=100, Recruiting, Sponsor: University of Miami
Trial primary completion date: Mar 2015 --> Jul 2015 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial primary completion date: Temperature Study in Cesarean Section (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=45, Recruiting, Sponsor: Stanford University
Trial primary completion date: Dec 2015 --> Dec 2016 Trial primary completion date: Jul 2011 --> Dec 2015
- Trial initiation date, Trial primary completion date: E-Chill: Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=15, Not yet recruiting, Sponsor: Lawson Health Research Institute
Trial primary completion date: Jul 2011 --> Dec 2015 Initiation date: Mar 2015 --> Sep 2015 | Trial primary completion date: Mar 2017 --> Sep 2017
- New trial, Surgery: Comparison of Forced Air and Conductive Patient Heating Systems During Ambulatory Surgeries (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=50, Not yet recruiting, Sponsor: Fox Valley Orthopedic Institute
- Enrollment open: TEM-C: Temperature Evaluation by MRI Thermometry During Cervical Cooling (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=10, Recruiting, Sponsor: University of Vermont
Initiation date: Mar 2015 --> Sep 2015 | Trial primary completion date: Mar 2017 --> Sep 2017 Not yet recruiting --> Recruiting
- Trial completion, Enrollment change: Foot Skin Temperature and Balance Control (clinicaltrials.gov) - Jun 9, 2015
P=N/A, N=8, Completed, Sponsor: Dr. Stephen Perry
Not yet recruiting --> Recruiting Recruiting --> Completed | N=10 --> 8
- Enrollment change, Trial withdrawal: MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE) (clinicaltrials.gov) - Jun 3, 2015
P=N/A, N=0, Withdrawn, Sponsor: Vanderbilt University
Recruiting --> Completed | N=10 --> 8 N=10 --> 0 | Recruiting --> Withdrawn
- Trial completion, Enrollment change: Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants (clinicaltrials.gov) - Jun 1, 2015
P2, N=5, Completed, Sponsor: Uta Lichter-Konecki
N=10 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | N=24 --> 5
- | Trial completion, Enrollment change, Trial primary completion date: SPARC: The Strategies for Post Arrest Resuscitation and Care Network (clinicaltrials.gov) - May 27, 2015
P=N/A, N=32, Completed, Sponsor: St. Michael's Hospital, Toronto
Recruiting --> Completed | N=24 --> 5 Active, not recruiting --> Completed | N=43 --> 32 | Trial primary completion date: Jan 2012 --> Dec 2010
- Enrollment change, Trial termination, Trial primary completion date: The Intravascular Cooling in the Treatment of Stroke 2/3 Trial (clinicaltrials.gov) - May 26, 2015
P2/3, N=120, Terminated, Sponsor: University of California, San Diego
N=400 --> 120 | Active, not recruiting --> Terminated | Trial primary completion date: Nov 2016 --> Apr 2015; The ICTuS 2 portion of the trial has been halted and data will be analyzed. The study will resume as ICTuS 3
- New trial: HEAT: Hypothermia and the Effect of Ambient Temperature (clinicaltrials.gov) - May 6, 2015
P=N/A, N=900, Recruiting, Sponsor: University of Texas Southwestern Medical Center
- | rocuronium / Generic mfg.
Trial completion, Trial primary completion date: Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest (clinicaltrials.gov) - May 1, 2015
P3, N=60, Completed, Sponsor: Medical University of Vienna
The study will resume as ICTuS 3 Recruiting --> Completed | Trial primary completion date: Jan 2013 --> Oct 2013
- New trial: TEM-C: Temperature Evaluation by MRI Thermometry During Cervical Cooling (clinicaltrials.gov) - Apr 30, 2015
P=N/A, N=10, Not yet recruiting, Sponsor: University of Vermont
- Trial completion: SjO2: Jugular Venous Oxygen Saturation During Therapeutic Hypothermia After Cardiac Arrest (clinicaltrials.gov) - Apr 28, 2015
P=N/A, N=15, Completed, Sponsor: Policlinico Hospital
Recruiting --> Completed | Trial primary completion date: Jan 2013 --> Oct 2013 Active, not recruiting --> Completed
- || Trial primary completion date: Prehospital Resuscitation Intra Nasal Cooling Effectiveness Survival Study (clinicaltrials.gov) - Apr 27, 2015
P2, N=900, Recruiting, Sponsor: Karolinska Institutet
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Dec 2016
- | Trial completion, Enrollment change: Does Environmental Factors Affect Accuracy in Pre-hospital Non-invasive Temperature Measurement? (clinicaltrials.gov) - Apr 27, 2015
P=N/A, N=13, Completed, Sponsor: Oslo University Hospital
Trial primary completion date: Dec 2015 --> Dec 2016 Active, not recruiting --> Completed | N=10 --> 13
- Trial completion, Enrollment change, Trial primary completion date, Surgery: Targeted Hypothermia During Cardiac Surgery (clinicaltrials.gov) - Apr 17, 2015
P1, N=5, Completed, Sponsor: NeuroSave Inc.
Active, not recruiting --> Completed | N=10 --> 13 Recruiting --> Completed | N=20 --> 5 | Trial primary completion date: Dec 2014 --> Mar 2015
- Trial initiation date, Trial primary completion date: Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients With Intravenous Infusion of Magnesium Sulfate (clinicaltrials.gov) - Apr 15, 2015
P2, N=14, Not yet recruiting, Sponsor: Life Recovery Systems
Recruiting --> Completed | N=20 --> 5 | Trial primary completion date: Dec 2014 --> Mar 2015 Initiation date: Nov 2012 --> Nov 2015 | Trial primary completion date: Nov 2013 --> Nov 2016
- ||||| New P2 trial: RECCLAIM-II: REperfusion With Cooling in CerebraL Acute IscheMia II (clinicaltrials.gov) - Apr 8, 2015
P2, N=85, Not yet recruiting, Sponsor: WellStar Health System
- dobutamine / Generic mfg.
Enrollment open: THE-COOL: Esophageal Temperature Management After Cardiac Arrest (clinicaltrials.gov) - Mar 31, 2015
P=N/A, N=15, Recruiting, Sponsor: IST cardiology
Initiation date: Nov 2012 --> Nov 2015 | Trial primary completion date: Nov 2013 --> Nov 2016 Not yet recruiting --> Recruiting
- ||| Clinical: Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest (clinicaltrials.gov) - Mar 19, 2015
P=N/A, N=100, Recruiting, Sponsor: University of Aarhus
- | Enrollment closed: Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial (clinicaltrials.gov) - Mar 17, 2015
P3, N=500, Active, not recruiting, Sponsor: University of Michigan
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Clinical: E-Chill: Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients (clinicaltrials.gov) - Mar 14, 2015
P=N/A, N=15, Recruiting, Sponsor: Lawson Health Research Institute
- Biomarker, Enrollment change, Trial primary completion date: MARBLE: Magnetic Resonance Biomarkers in Neonatal Encephalopathy (clinicaltrials.gov) - Feb 24, 2015
P=N/A, N=180, Recruiting, Sponsor: Thayyil, Sudhin
Recruiting --> Active, not recruiting N=120 --> 180 | Trial primary completion date: Mar 2014 --> Mar 2016
- Trial completion, Enrollment change, Trial primary completion date: HELIX-I: Hypothermia for Encephalopathy in Low Income Countries-Feasibilty (clinicaltrials.gov) - Feb 24, 2015
P=N/A, N=62, Completed, Sponsor: Thayyil, Sudhin
N=120 --> 180 | Trial primary completion date: Mar 2014 --> Mar 2016 Not yet recruiting --> Completed | N=50 --> 62 | Trial primary completion date: Jul 2013 --> Dec 2014
- Trial completion: Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IV (clinicaltrials.gov) - Feb 24, 2015
P4, N=118, Completed, Sponsor: University of Alabama at Birmingham
Not yet recruiting --> Completed | N=50 --> 62 | Trial primary completion date: Jul 2013 --> Dec 2014 Recruiting --> Completed
- Trial primary completion date: Kangaroo Mother Care to Prevent Hypothermia in Term Infants (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=400, Recruiting, Sponsor: University of Alabama at Birmingham
Recruiting --> Completed Trial primary completion date: Dec 2014 --> Aug 2014
- Trial primary completion date: Kangaroo Mother Care to Prevent Hypothermia in Preterm Infants (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=220, Recruiting, Sponsor: University of Alabama at Birmingham
Trial primary completion date: Dec 2014 --> Aug 2014 Trial primary completion date: Dec 2014 --> Dec 2015