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18 Companies |
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15 Products |
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15 Products |
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33 Mechanisms of Action |
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0 Trials |
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35 News |
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- | saracatinib (AZD0530) / AstraZeneca
Enrollment change: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Jul 3, 2018
P2, N=17, Completed, Sponsor: National Cancer Institute (NCI)
N=37 --> 17
- | Istodax (romidepsin) / Astellas, BMS
Trial completion, Trial initiation date, Trial primary completion date, Metastases: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma (clinicaltrials.gov) - Jun 14, 2017
P2, N=40, Completed, Sponsor: National Cancer Institute (NCI)
N=37 --> 17 Active, not recruiting --> Completed | Initiation date: Jan 2004 --> Jan 2005 | Trial primary completion date: Jul 2013 --> Oct 2008
- | NN1213 / Novo Nordisk
Trial completion, Surgery: Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis (clinicaltrials.gov) - Jul 4, 2016
P3, N=370, Completed, Sponsor: Alliance for Clinical Trials in Oncology
Active, not recruiting --> Completed | Initiation date: Jan 2004 --> Jan 2005 | Trial primary completion date: Jul 2013 --> Oct 2008 No longer recruiting --> Completed
- Trial completion, Enrollment change: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy (clinicaltrials.gov) - Dec 6, 2015
P=N/A, N=20, Completed, Sponsor: St. Jude Children's Research Hospital
No longer recruiting --> Completed Active, not recruiting --> Completed | N=50 --> 20
- Enrollment closed, Trial primary completion date: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy (clinicaltrials.gov) - Oct 1, 2015
P=N/A, N=50, Active, not recruiting, Sponsor: St. Jude Children's Research Hospital
Active, not recruiting --> Completed | N=50 --> 20 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Nov 2015
- | Neulasta (pegfilgrastim) / Roche
Trial completion, Metastases: Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Oct 27, 2014
P3, N=455, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2016 --> Nov 2015 Active, not recruiting --> Completed
- Yondelis (trabectedin) / PharmaMar, J&J
Enrollment change, Metastases: Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Aug 8, 2014
P2b, N=133, Terminated, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed N=370 --> 133
- | Granocyte (lenograstim) / Roche
Trial completion, Surgery: EORTC-STBSG 62931: Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma (clinicaltrials.gov) - Aug 8, 2014
P3, N=350, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
N=370 --> 133 Active, not recruiting --> Completed
- Enrollment change, Surgery: Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma (clinicaltrials.gov) - Mar 26, 2014
P2, N=1, Terminated, Sponsor: City of Hope Medical Center
Active, not recruiting --> Completed N=30 --> 1
- NN1213 / Novo Nordisk
Trial completion, Metastases: Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Daiichi Sankyo Inc.
N=30 --> 1 Suspended --> Completed
- | imatinib / Generic mfg.
Trial completion, Metastases: Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: National Cancer Institute (NCI)
Suspended --> Completed No longer recruiting --> Completed
- | Trial completion, Surgery: Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma (clinicaltrials.gov) - Nov 25, 2013
P3, N=400, Completed, Sponsor: Societe Internationale d'Oncologie Pediatrique
No longer recruiting --> Completed Active, not recruiting --> Completed
- sorafenib / Generic mfg.
Enrollment change: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma (clinicaltrials.gov) - Nov 18, 2013
P2, N=147, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed N=222 --> 147
- BI2536 / Boehringer Ingelheim
Trial completion, Metastases: BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors (clinicaltrials.gov) - Oct 3, 2013
P2, N=76, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
N=222 --> 147 Active, not recruiting --> Completed
- BI2536 / Boehringer Ingelheim
Enrollment change, Metastases: BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors (clinicaltrials.gov) - Sep 19, 2013
P2, N=76, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed N=185 --> 76
- | Trial completion: Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma (clinicaltrials.gov) - Sep 12, 2013
P3, N=340, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
N=185 --> 76 Active, not recruiting --> Completed
- Yondelis (trabectedin) / PharmaMar, J&J
Trial termination, Metastases: Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Aug 25, 2013
P2b, N=370, Terminated, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Suspended --> Terminated; Results of step1: none of the experimental arms fulfills expectations and the study will not continue as a phase III.
- Enrollment change: Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma (clinicaltrials.gov) - Jul 8, 2013
P=N/A, N=0, Withdrawn, Sponsor: Children's Oncology Group
Suspended --> Terminated; Results of step1: none of the experimental arms fulfills expectations and the study will not continue as a phase III. N=180 --> 0
- saracatinib (AZD0530) / AstraZeneca
Trial completion: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - May 6, 2013
P2, N=37, Completed, Sponsor: National Cancer Institute (NCI)
N=180 --> 0 Active, not recruiting --> Completed
- sunitinib / Generic mfg.
Enrollment change, Metastases: Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas (clinicaltrials.gov) - Mar 19, 2013
P2, N=52, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed N=102 --> 52
- celecoxib oral / Generic mfg.
Enrollment change, Surgery: Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery (clinicaltrials.gov) - Feb 17, 2013
P1, N=3, Completed, Sponsor: University of Miami Sylvester Comprehensive Cancer Center
N=102 --> 52 N=24 --> 3
- sorafenib / Generic mfg.
Trial completion: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma (clinicaltrials.gov) - Dec 12, 2012
P2, N=147, Completed, Sponsor: National Cancer Institute (NCI)
N=24 --> 3 Active, not recruiting --> Completed
- Torisel (temsirolimus) / Pfizer
Enrollment change, Metastases: Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma (clinicaltrials.gov) - Sep 23, 2012
P1/2, N=24, Completed, Sponsor: Sidney Kimmel Comprehensive Cancer Center
Active, not recruiting --> Completed N=45 --> 24
- Torisel (temsirolimus) / Pfizer
Trial completion, Metastases: Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma (clinicaltrials.gov) - Sep 23, 2012
P1/2, N=24, Completed, Sponsor: Sidney Kimmel Comprehensive Cancer Center
N=45 --> 24 Recruiting --> Completed
- imatinib / Generic mfg.
Enrollment change, Metastases: Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma (clinicaltrials.gov) - Sep 19, 2012
P2, N=17, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Recruiting --> Completed N=44 --> 17
- Yondelis (trabectedin) / PharmaMar, J&J
Enrollment change, Metastases: Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma (clinicaltrials.gov) - Sep 19, 2012
P2, N=132, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
N=44 --> 17 N=44 --> 132
- imatinib / Generic mfg.
Trial completion, Metastases: Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma (clinicaltrials.gov) - Sep 19, 2012
P2, N=17, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
N=44 --> 132 Active, not recruiting --> Completed
- pegylated liposomal doxorubicin / Generic mfg., ifosfamide / Generic mfg.
Trial completion, Combination therapy, Metastases: Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Sep 19, 2012
P1, N=28, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed
- imatinib / Generic mfg.
Trial completion, Metastases: STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma (clinicaltrials.gov) - Sep 19, 2012
P2, N=91, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Yondelis (trabectedin) / PharmaMar, J&J
Trial completion, Metastases: Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma (clinicaltrials.gov) - Sep 19, 2012
P2, N=132, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment open: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy (clinicaltrials.gov) - Sep 5, 2012
P=N/A, N=50, Recruiting, Sponsor: St. Jude Children's Research Hospital
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- brostallicin (PNU-166196) / SOBI
Trial completion, Metastases: Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Jul 16, 2012
P2, N=64, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Trial completion, Metastases: Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma (clinicaltrials.gov) - Jul 16, 2012
P2, N=39, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion, Surgery: SWOG-EORTC-62933: Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma (clinicaltrials.gov) - Jul 9, 2012
P3, N=340, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | ifosfamide / Generic mfg., doxorubicin hydrochloride / Generic mfg.
Trial completion, Metastases: Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma (clinicaltrials.gov) - Jan 18, 2012
P3, N=780, Completed, Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Active, not recruiting --> Completed Active, not recruiting --> Completed