- |||||||||| Lexiscan (regadenoson) / GE Healthcare, Astellas, Gilead
Trial completion: A Phase II Trial of Regadenoson in Sickle Cell Anemia (clinicaltrials.gov) - Feb 7, 2018 P2, N=100, Completed, Active, not recruiting --> Completed | Trial completion date: Apr 2017 --> May 2017 Recruiting --> Completed
- |||||||||| Trial completion, Trial primary completion date: Vitamin D3 in Patients With Sickle Cell Disease (clinicaltrials.gov) - Jan 19, 2018
P=N/A, N=50, Completed, Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Dec 2017 --> Aug 2016
- |||||||||| NVX-508 / NuvOx Pharma
Trial initiation date, Trial primary completion date: A Phase Ib Study of NVX-508 in Sickle Cell Disease (clinicaltrials.gov) - Dec 14, 2017 P1, N=24, Not yet recruiting, N=194 --> 87 Initiation date: Nov 2017 --> Feb 2018 | Trial primary completion date: May 2018 --> Aug 2018
- |||||||||| Trial completion, Phase classification, Immunomodulating: the Potential Immunomodulatory Effects of Spirulina on Thalassemic Children (clinicaltrials.gov) - Oct 25, 2017
P=N/A, N=60, Completed, Recruiting --> Active, not recruiting | N=134 --> 91 | Trial primary completion date: Aug 2017 --> Dec 2017 Active, not recruiting --> Completed | Phase classification: P4 --> PN/A
- |||||||||| hydroxyurea / Generic mfg.
Trial completion, Trial primary completion date: Hydroxyurea in the Treatment of Sickle Cell Disease (clinicaltrials.gov) - Oct 6, 2017 P=N/A, N=628, Completed, Trial primary completion date: Apr 2017 --> Apr 2018 Active, not recruiting --> Completed | Trial primary completion date: Mar 2016 --> Nov 2016
- |||||||||| NVX-508 / NuvOx Pharma
Trial primary completion date: A Phase Ib Study of NVX-508 in Sickle Cell Disease (clinicaltrials.gov) - Oct 5, 2017 P1, N=24, Not yet recruiting, Active, not recruiting --> Completed Trial primary completion date: Dec 2017 --> May 2018
- |||||||||| Trial completion: Heart Disease in Sickle Cell Anemia (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=120, Completed, Completed --> Terminated; The study terminated early due to slow accrual. Recruiting --> Completed
- |||||||||| propranolol ER / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease (clinicaltrials.gov) - Jun 8, 2017 P1, N=9, Terminated, Not yet recruiting --> Recruiting N=20 --> 9 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Nov 2012; Inability to recruit patients into the study.
- |||||||||| Amevive (alefacept) / Astellas
Trial termination: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Jun 7, 2017 P=N/A, N=3, Terminated, N=20 --> 9 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Nov 2012; Inability to recruit patients into the study. Suspended --> Terminated; drug company is no longer making the drug
- |||||||||| Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
Trial completion, Enrollment change, Trial primary completion date: Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease (clinicaltrials.gov) - May 15, 2017 P2, N=22, Completed, Recruiting --> Completed | Trial primary completion date: May 2017 --> Aug 2016 Active, not recruiting --> Completed | N=15 --> 22 | Trial primary completion date: Dec 2017 --> Jun 2016
- |||||||||| Trial completion, Enrollment change, Trial primary completion date: A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease (clinicaltrials.gov) - May 3, 2017
P=N/A, N=28, Completed, Active, not recruiting --> Completed | N=15 --> 22 | Trial primary completion date: Dec 2017 --> Jun 2016 Recruiting --> Completed | N=40 --> 28 | Trial primary completion date: Dec 2016 --> Dec 2015
- |||||||||| Trial completion, Trial primary completion date: MBSR for Pain Catastrophizing in SCD (clinicaltrials.gov) - Apr 26, 2017
P=N/A, N=60, Completed, Phase classification: P4 --> P=N/A | Trial primary completion date: Mar 2017 --> Oct 2017 Active, not recruiting --> Completed | Trial primary completion date: Jun 2016 --> Jan 2016
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