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11 Companies |
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10 Products |
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10 Products |
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12 Mechanisms of Action |
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0 Trials |
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39 News |
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- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial completion, Trial completion date, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Feb 15, 2019
P1, N=20, Completed, Sponsor: University of Colorado, Denver
Active, not recruiting --> Completed | Trial completion date: Aug 2019 --> Feb 2019
- | Trial completion, Trial completion date: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Nov 10, 2018
P2, N=15, Completed, Sponsor: Baylor College of Medicine
Active, not recruiting --> Completed | Trial completion date: Aug 2019 --> Feb 2019 Active, not recruiting --> Completed | Trial completion date: Jul 2018 --> Nov 2017
- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial completion date, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Sep 6, 2018
P1, N=20, Active, not recruiting, Sponsor: University of Colorado, Denver
Active, not recruiting --> Completed | Trial completion date: Jul 2018 --> Nov 2017 Trial completion date: Aug 2018 --> Aug 2019
- | Phase classification, Enrollment change: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease (clinicaltrials.gov) - Apr 6, 2018
P, N=33, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial completion date: Aug 2018 --> Aug 2019 Phase classification: P=N/A --> P | N=60 --> 33
- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial completion date, Trial primary completion date, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Mar 3, 2018
P1, N=20, Active, not recruiting, Sponsor: University of Colorado, Denver
Phase classification: P=N/A --> P | N=60 --> 33 Trial completion date: Feb 2018 --> Apr 2018 | Trial primary completion date: Feb 2018 --> Apr 2018
- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial primary completion date, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Dec 13, 2017
P1, N=20, Active, not recruiting, Sponsor: University of Colorado, Denver
Trial completion date: Feb 2018 --> Apr 2018 | Trial primary completion date: Feb 2018 --> Apr 2018 Trial primary completion date: Nov 2017 --> Feb 2018
- | Enrollment change, Trial termination: FIBRO CGD: Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease. (clinicaltrials.gov) - Sep 29, 2017
P=N/A, N=3, Terminated, Sponsor: University Hospital, Grenoble
Trial primary completion date: Nov 2017 --> Feb 2018 N=10 --> 3 | Recruiting --> Terminated; insufficient recruitment
- | Trial primary completion date: Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease (clinicaltrials.gov) - Sep 20, 2017
P4, N=2, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
N=10 --> 3 | Recruiting --> Terminated; insufficient recruitment Trial primary completion date: Feb 2017 --> Nov 2014
- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Enrollment closed, Enrollment change, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Sep 20, 2017
P1, N=20, Active, not recruiting, Sponsor: University of Colorado, Denver
Trial primary completion date: Feb 2017 --> Nov 2014 Recruiting --> Active, not recruiting | N=30 --> 20
- | Trial completion, Trial primary completion date: DIPobiota: Study of Gut Microbiota in Primary Immune Deficiency, Possibly Associated With Inflammatory Bowel Disease (clinicaltrials.gov) - Aug 25, 2017
P=N/A, N=51, Completed, Sponsor: Imagine Institute
Recruiting --> Active, not recruiting | N=30 --> 20 Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Feb 2017
- | Enrollment closed: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Jul 18, 2017
P2, N=15, Active, not recruiting, Sponsor: Baylor College of Medicine
Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Feb 2017 Recruiting --> Active, not recruiting
- | busulfan / Generic mfg.
Trial completion: Use of Busulfan as Conditioning Agent for a Second Stem Cell Transplant (clinicaltrials.gov) - Jun 30, 2017
P1, N=2, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | Noxafil (posaconazole) / Merck (MSD)
Trial completion: Posaconazole to Treat Invasive Fungal Infections (clinicaltrials.gov) - Jun 30, 2017
P3, N=50, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed No longer recruiting --> Completed
- | Trial completion, Gene therapy: Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up (clinicaltrials.gov) - Jun 30, 2017
P1, N=14, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Amevive (alefacept) / Astellas
Trial termination: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Jun 7, 2017
P=N/A, N=3, Terminated, Sponsor: Emory University
Active, not recruiting --> Completed Suspended --> Terminated; drug company is no longer making the drug
- | Phase classification, Gene therapy: Gene Therapy for Chronic Granulomatous Disease (clinicaltrials.gov) - Apr 20, 2017
P, N=3, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Suspended --> Terminated; drug company is no longer making the drug Phase classification: P=N/A --> P
- Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Enrollment open, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Nov 25, 2016
P1, N=30, Recruiting, Sponsor: University of Colorado, Denver
Phase classification: P=N/A --> P Not yet recruiting --> Recruiting
- New trial: FIBRO CGD: Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease. (clinicaltrials.gov) - Oct 6, 2016
P=N/A, N=10, Recruiting, Sponsor: University Hospital, Grenoble
- New trial: DIPobiota: Study of Gut Microbiota in Primary Immune Deficiency, Possibly Associated With Inflammatory Bowel Disease (clinicaltrials.gov) - Sep 21, 2016
P=N/A, N=50, Recruiting, Sponsor: Imagine Institute
- Trial primary completion date: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Jul 21, 2016
P2, N=15, Recruiting, Sponsor: Baylor College of Medicine
Not yet recruiting --> Recruiting Trial primary completion date: Mar 2017 --> Nov 2017
- Trial primary completion date: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Jul 19, 2016
P2, N=15, Recruiting, Sponsor: Baylor College of Medicine
Trial primary completion date: Mar 2017 --> Nov 2017 Trial primary completion date: Mar 2016 --> Mar 2017
- Trial completion, Trial primary completion date: Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells (clinicaltrials.gov) - Jun 23, 2016
P1/2, N=25, Completed, Sponsor: Children's Hospital Los Angeles
Trial primary completion date: Mar 2016 --> Mar 2017 Recruiting --> Completed | Trial primary completion date: Aug 2012 --> Aug 2015
- Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial initiation date, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Jun 5, 2016
P1, N=30, Not yet recruiting, Sponsor: University of Colorado, Denver
Recruiting --> Completed | Trial primary completion date: Aug 2012 --> Aug 2015 Initiation date: Dec 2015 --> Jul 2016
- Trial completion, Trial primary completion date: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=60, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Initiation date: Dec 2015 --> Jul 2016 Recruiting --> Completed | Trial primary completion date: Jun 2016 --> Jan 2016
- Actimmune (interferon gamma-1 b) / Clinigen, Amgen
New P1 trial, Immune cell: Effect of IFN-? on Innate Immune Cells (clinicaltrials.gov) - Nov 21, 2015
P1, N=30, Not yet recruiting, Sponsor: University of Colorado, Denver
- New P2 trial: Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells (clinicaltrials.gov) - Jul 31, 2015
P2, N=20, Completed, Sponsor: Children's Hospital Los Angeles
- Trial primary completion date: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Mar 12, 2015
P2, N=15, Recruiting, Sponsor: Baylor College of Medicine
Recruiting --> Completed | Trial primary completion date: Jun 2016 --> Jan 2016 Trial primary completion date: Sep 2015 --> Mar 2016
- Trial primary completion date: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=60, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Sep 2015 --> Mar 2016 Trial primary completion date: Feb 2015 --> Jun 2016
- Enrollment change, Trial termination: Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease (clinicaltrials.gov) - Dec 29, 2014
P4, N=3, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Feb 2015 --> Jun 2016 N=70 --> 3 | Recruiting --> Terminated; Early termination due to only 2 subjects completing trial.
- fludarabine IV / Generic mfg., mycophenolate mofetil / Generic mfg., cyclosporine / Generic mfg.
Trial completion, Combination therapy: Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=20, Completed, Sponsor: Fred Hutchinson Cancer Research Center
N=70 --> 3 | Recruiting --> Terminated; Early termination due to only 2 subjects completing trial. Active, not recruiting --> Completed
- Trial primary completion date: MUNCHR: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease (clinicaltrials.gov) - Sep 10, 2014
P2, N=15, Recruiting, Sponsor: Baylor College of Medicine
Active, not recruiting --> Completed Trial primary completion date: Feb 2015 --> Sep 2015
- Clinical: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease (clinicaltrials.gov) - Sep 8, 2014
P=N/A, N=60, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- Trial termination, Gene therapy: Gene Therapy for Chronic Granulomatous Disease (clinicaltrials.gov) - Apr 8, 2014
P0, N=3, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Feb 2015 --> Sep 2015 Recruiting --> Terminated
- Remicade (infliximab) / Merck (MSD), Mitsubishi Tanabe, J&J, Humira (adalimumab) / AbbVie
Enrollment change: Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease (clinicaltrials.gov) - Jun 1, 2012
P1/2, N=41, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Terminated N=75 --> 41
- Remicade (infliximab) / Merck (MSD), Mitsubishi Tanabe, J&J, Humira (adalimumab) / AbbVie
Trial completion: Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease (clinicaltrials.gov) - Jun 1, 2012
P1/2, N=41, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
N=75 --> 41 Recruiting --> Completed
- Trial withdrawal, Gene therapy: Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD) (clinicaltrials.gov) - May 31, 2012
P1/2, N=0, Withdrawn, Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust
Recruiting --> Completed Not yet recruiting --> Withdrawn
- Enrollment change, Gene therapy: Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD) (clinicaltrials.gov) - May 31, 2012
P1/2, N=0, Withdrawn, Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust
Not yet recruiting --> Withdrawn N=10 --> 0
- Amevive (alefacept) / Astellas
Trial suspension: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation (clinicaltrials.gov) - Apr 3, 2012
P=N/A, N=5, Suspended, Sponsor: Emory University
N=10 --> 0 Recruiting --> Suspended
- Trial completion, Gene therapy: XCGDinChildren: Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in Children (clinicaltrials.gov) - Sep 25, 2011
P1/2, N=2, Completed, Sponsor: University of Zurich
Recruiting --> Suspended Active, not recruiting --> Completed