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90 Companies |
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65 Products |
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65 Products |
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50 Mechanisms of Action |
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828 Trials |
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64398 News |
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- ||||| AMA0076 / Akari Therap
New P2 trial: Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma (clinicaltrials.gov) - Sep 24, 2012
P2, N=82, Completed, Sponsor: Amakem, NV
- | bamosiran (SYL040012) / PharmaMar
Trial completion: SYL040012. Tolerance and Effect on Intraocular Pressure in Subjects With Intraocular Pressure (IOP) >= 21 mm Hg (clinicaltrials.gov) - Sep 20, 2012
P1/2, N=30, Completed, Sponsor: Sylentis, S.A.
Recruiting --> Completed
- ||||||| bimatoprost/brimonidine/timolol / AbbVie
Trial completion, Combination therapy: Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Sep 20, 2012
P3, N=126, Completed, Sponsor: Allergan
Recruiting --> Completed Recruiting --> Completed
- Trial completion: Eyelid Closure in Glaucoma Therapy (clinicaltrials.gov) - Sep 18, 2012
P=N/A, N=60, Completed, Sponsor: Johns Hopkins University
Recruiting --> Completed Recruiting --> Completed
- brinzolamide/travoprost / Novartis
Enrollment change: Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT (clinicaltrials.gov) - Sep 17, 2012
P3, N=17, Terminated, Sponsor: Alcon Research
Recruiting --> Completed N=800 --> 17
- || New P3 trial: SLTRepeat: A Trial to Compare the Laser Treatment (SLT vs. ALT) in Glaucoma Patients (clinicaltrials.gov) - Sep 17, 2012
P3, N=144, Recruiting, Sponsor: Lawson Health Research Institute
- brimonidine tartrate / Generic mfg.
New P1 trial: Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Sep 17, 2012
P1, N=15, Completed, Sponsor: Eye Therapies, LLC
- Combigan (brimonidine tartrate/timolol maleate) / AbbVie
Trial termination, Combination therapy: Assessing the Efficacy and Tolerability of AZARGA (clinicaltrials.gov) - Sep 16, 2012
P4, N=9, Terminated, Sponsor: Alcon Research
N=800 --> 17 Recruiting --> Terminated; Low recruitment rate
- Combigan (brimonidine tartrate/timolol maleate) / AbbVie
Enrollment change, Combination therapy: Assessing the Efficacy and Tolerability of AZARGA (clinicaltrials.gov) - Sep 16, 2012
P4, N=9, Terminated, Sponsor: Alcon Research
Recruiting --> Terminated; Low recruitment rate N=52 --> 9
- Enrollment change: 24-hour Efficacy of AR-12286 (clinicaltrials.gov) - Sep 11, 2012
P2, N=5, Completed, Sponsor: Aerie Pharmaceuticals
N=52 --> 9 N=15 --> 5
- Trial completion: 24-hour Efficacy of AR-12286 (clinicaltrials.gov) - Sep 11, 2012
P2, N=5, Completed, Sponsor: Aerie Pharmaceuticals
N=15 --> 5 Recruiting --> Completed
- Enrollment change: Surgical Treatment of Refractory Open Angle Glaucoma (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=4, Completed, Sponsor: iScience Interventional Corporation
Recruiting --> Completed N=50 --> 4
- Trial completion: Surgical Treatment of Refractory Open Angle Glaucoma (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=4, Completed, Sponsor: iScience Interventional Corporation
N=50 --> 4 Enrolling by invitation --> Completed
- | New P4 trial: IVES: Pilot Study on the Use of Artificial Tears to Treat Dry Eye in Glaucoma Patients (clinicaltrials.gov) - Sep 9, 2012
P4, N=15, Completed, Sponsor: University of Waterloo
- | Trial completion: ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects (clinicaltrials.gov) - Sep 4, 2012
P2, N=12, Completed, Sponsor: Altheos, Inc.
Enrolling by invitation --> Completed Recruiting --> Completed
- latanoprost / Generic mfg.
Biomarker: Glaucoma Biomarkers (clinicaltrials.gov) - Aug 30, 2012
P=N/A, N=150, Recruiting, Sponsor: University of Michigan
- Zioptan (tafluprost) / Santen, Merck (MSD)
Enrollment change: Use of an Ocular Telemetry Sensor in Tafluprost Treated Patients (clinicaltrials.gov) - Aug 26, 2012
P4, N=15, Terminated, Sponsor: Sensimed AG
Recruiting --> Completed N=20 --> 15
- ||| sepetaprost (DE-126) / Santen
New P1 trial: Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma (clinicaltrials.gov) - Aug 20, 2012
P1, N=60, Completed, Sponsor: Ono Pharma USA Inc
- Clinical: Randomized Controlled Trial on Visual Field Training (clinicaltrials.gov) - Aug 16, 2012
P=N/A, N=200, Recruiting, Sponsor: Oftalmologia Hospital Sotero del Rio
- | New P2 trial: ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects (clinicaltrials.gov) - Aug 16, 2012
P2, N=12, Completed, Sponsor: Altheos, Inc.
- ||||| travoprost ophthalmic / Generic mfg.
Enrollment change: Travoprost 3-Month Safety and Efficacy Study (clinicaltrials.gov) - Aug 15, 2012
P3, N=1099, Completed, Sponsor: Alcon Research
N=20 --> 15 N=720 --> 1099
- Clinical: Risk Factors for Glaucoma in Musicians (clinicaltrials.gov) - Aug 15, 2012
P=N/A, N=40, Recruiting, Sponsor: Henny Beckers
- ||||||| travoprost ophthalmic / Generic mfg.
Trial completion: Travoprost 3-Month Safety and Efficacy Study (clinicaltrials.gov) - Aug 15, 2012
P3, N=1099, Completed, Sponsor: Alcon Research
N=720 --> 1099 Recruiting --> Completed
- ||| Trial completion, Compliance: Determinants of Compliance With Glaucoma Therapy (clinicaltrials.gov) - Aug 13, 2012
P=N/A, N=59, Completed, Sponsor: University of Alabama at Birmingham
Recruiting --> Completed Recruiting --> Completed
- | Lumigan (bimatoprost) / Senju, AbbVie
New P4 trial: An Efficacy and Tolerability Study of TRAVATAN (clinicaltrials.gov) - Aug 12, 2012
P4, N=104, Active, not recruiting, Sponsor: Alcon Research
- |||| Vyzulta (latanoprostene bunod) / Bausch Health, Nicox
Trial completion: Voyager: Study Comparing the Safety and Efficacy of BOL-303259-X to Latanoprost in Subjects With Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Aug 9, 2012
P2, N=355, Completed, Sponsor: Bausch & Lomb Incorporated
Recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor (clinicaltrials.gov) - Aug 6, 2012
P=N/A, N=33, Completed, Sponsor: Sensimed AG
Active, not recruiting --> Completed Recruiting --> Completed
- ||| Trial completion: SENSIMED Triggerfish (clinicaltrials.gov) - Aug 6, 2012
P=N/A, N=59, Completed, Sponsor: Sensimed AG
Recruiting --> Completed Recruiting --> Completed
- | travoprost ophthalmic / Generic mfg.
New P1 trial: Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients (clinicaltrials.gov) - Aug 5, 2012
P1, N=25, Completed, Sponsor: Alcon Research
- | Lumigan (bimatoprost) / Senju, AbbVie
New P4 trial: 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension (clinicaltrials.gov) - Jul 31, 2012
P4, N=61, Completed, Sponsor: University of Parma
- |||| LX7101 / Lexicon Pharma
Trial completion: Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Jul 31, 2012
P1/2, N=63, Completed, Sponsor: Lexicon Pharmaceuticals
Recruiting --> Completed Active, not recruiting --> Completed
- ||||| Omlonti (omidenepag isopropyl) / Santen, Ube Corp
New P1/2 trial: A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT (clinicaltrials.gov) - Jul 29, 2012
P1/2, N=60, Completed, Sponsor: Santen Inc.
- Enrollment change: Does Glaucoma Cause Loss of Brain Function? (clinicaltrials.gov) - Jul 26, 2012
P=N/A, N=37, Completed, Sponsor: Wills Eye
Active, not recruiting --> Completed N=20 --> 37
- |||||||||| timolol maleate ophthalmic solution / Generic mfg., travoprost ophthalmic / Generic mfg.
New P3 trial: Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients (clinicaltrials.gov) - Jul 26, 2012
P3, N=184, Completed, Sponsor: Alcon Research
- Renexus (revakinagene taroretcel) / Neurotech Pharma
Enrollment closed: NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and Neuroenhancement (clinicaltrials.gov) - Jul 25, 2012
P1, N=11, Active, not recruiting, Sponsor: Jeffrey L. Goldberg
N=20 --> 37 Recruiting --> Active, not recruiting
- Taptiqom (tafluprost/timolol) / Santen, AGC Biologics
Trial completion: DE-111 Against Timolol Ophthalmic Solution 0.5% (clinicaltrials.gov) - Jul 25, 2012
P3, N=0, Completed, Sponsor: Santen Pharmaceutical Co., Ltd.
Recruiting --> Active, not recruiting Recruiting --> Completed
- Taptiqom (tafluprost/timolol) / Santen, AGC Biologics
Trial completion: DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5% (clinicaltrials.gov) - Jul 25, 2012
P3, N=0, Completed, Sponsor: Santen Pharmaceutical Co., Ltd.
Recruiting --> Completed Recruiting --> Completed
- | Combigan (brimonidine tartrate/timolol maleate) / AbbVie
Trial completion: Comparing Effects of Two Fixed Combinations Ophthalmic Solutions on Ocular Blood Flow (clinicaltrials.gov) - Jul 24, 2012
P4, N=15, Completed, Sponsor: Allergan
Recruiting --> Completed Active, not recruiting --> Completed
- ||| OPA-6566 / Kubota
Enrollment change: Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Jul 17, 2012
P1/2, N=160, Completed, Sponsor: Acucela Inc.
Active, not recruiting --> Completed N=120 --> 160
- Rhopressa (netarsudil) / Aerie Pharma
Clinical: Study of AR-13324 in Patients With Elevated Intraocular Pressure (clinicaltrials.gov) - Jul 17, 2012
P2, N=85, Completed, Sponsor: Aerie Pharmaceuticals
N=120 --> 160 Active, not recruiting --> Completed
- ||| Trial completion: Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT) (clinicaltrials.gov) - Jul 15, 2012
P=N/A, N=102, Completed, Sponsor: Allergan
Active, not recruiting --> Completed Recruiting --> Completed
- |||||||||| New P3 trial: AqueSys Microfistula Implant in Refractory Glaucoma (clinicaltrials.gov) - Jul 12, 2012
P3, N=60, Active, not recruiting, Sponsor: AqueSys, Inc.
- latanoprost / Generic mfg.
Clinical: Clinical Evaluation of Efficacy of SLT to Topical Medication in Lowering IOP (clinicaltrials.gov) - Jul 11, 2012
P=N/A, N=600, Recruiting, Sponsor: Aurolab
- latanoprost / Generic mfg.
Enrollment closed: Clinical Evaluation of Safety and Efficacy of Refrigeration Free Latanoprost (clinicaltrials.gov) - Jul 10, 2012
P=N/A, N=30, Active, not recruiting, Sponsor: Aurolab
Recruiting --> Completed Recruiting --> Active, not recruiting
- ||| Monotherapy: A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy (clinicaltrials.gov) - Jul 9, 2012
P=N/A, N=4385, Completed, Sponsor: Allergan
- || Enrollment change: CyCLE: CyPass Clinical Experience Study (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=2000, Active, not recruiting, Sponsor: Transcend Medical, Inc.
Recruiting --> Active, not recruiting N=500 --> 2000
- || Enrollment closed: CyCLE: CyPass Clinical Experience Study (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=2000, Active, not recruiting, Sponsor: Transcend Medical, Inc.
N=500 --> 2000 Enrolling by invitation --> Active, not recruiting
- Clinical: Re-Trabeculectomy Versus Ahmed Glaucoma Valve Implantation in Secondary Surgical Management of Patients With Refractory Glaucoma (clinicaltrials.gov) - Jul 2, 2012
P=N/A, N=100, Completed, Sponsor: Vanak Eye Surgery Center
- || Enrollment closed: DUETTE: Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy (clinicaltrials.gov) - Jul 2, 2012
P=N/A, N=75, Active, not recruiting, Sponsor: Transcend Medical, Inc.
Enrolling by invitation --> Active, not recruiting Recruiting --> Active, not recruiting
- apraclonidine / Generic mfg.
Enrollment closed: Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma (clinicaltrials.gov) - Jul 2, 2012
P=N/A, N=138, Active, not recruiting, Sponsor: Laval University
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting