Glaucoma News - LARVOL Sigma

Glaucoma

Welcome, Profile Billing Logout

50 Mechanisms of Action

«1 2...694 695 696 697 698699700 701 702 703 704...706 707 »

||||||||||  Lumigan (bimatoprost) / Senju, AbbVie
Trial completion:  A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) -  Jul 2, 2013
P=N/A, N=2583, Completed,  Sponsor: Allergan
Recruiting --> Completed

|||||||||| Trial completion: Optical Coherence Tomography (OCT) Data Collection Study (clinicaltrials.gov) - Jul 2, 2013
P=N/A, N=322, Completed, Sponsor: Heidelberg Engineering GmbH
Recruiting --> Completed Recruiting --> Completed

|||||||||| New P1 trial: Safety of Hyaluronan Thiomer i.o. Implant During Combined Phacoemulsification - Non Penetrating Deep Sclerectomy (clinicaltrials.gov) - Jun 25, 2013
P1, N=16, Recruiting, Sponsor: Croma-Pharma GmbH

||||||||||  5-fluorouracil / Generic mfg.
New P2 trial:  Transconjunctival Needling Revision Versus Medical Treatment (clinicaltrials.gov) -  Jun 24, 2013
P2, N=40, Completed,  Sponsor: University of Sao Paulo General Hospital

|||||||||| Enrollment open: Safety of Hyaluronan Thiomer i.o. Implant During Combined Phacoemulsification - Non Penetrating Deep Sclerectomy (clinicaltrials.gov) - Jun 24, 2013
P1, N=16, Recruiting, Sponsor: Croma-Pharma GmbH
Recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| Enrollment open: IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients (clinicaltrials.gov) - Jun 23, 2013
P=N/A, N=210, Recruiting, Sponsor: University of Zurich
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting

|||||||||| Trial completion: Macular Ganglion Cell Analysis (GCA) of the Cirrus HD-OCT in Glaucoma (clinicaltrials.gov) - Jun 23, 2013
P=N/A, N=119, Completed, Sponsor: Carl Zeiss Meditec, Inc.
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| Trial completion: Astigmatism Post-trabeculectomy (clinicaltrials.gov) - Jun 21, 2013
P=N/A, N=52, Completed, Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  latanoprost / Generic mfg., travoprost ophthalmic / Generic mfg.
Trial completion, Monotherapy:  Efficacy of Changing to TRAVATAN (clinicaltrials.gov) -  Jun 20, 2013
P4, N=190, Completed,  Sponsor: Alcon Research
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Combigan (brimonidine tartrate/timolol maleate) / AbbVie
Trial completion:  Efficacy and Tolerability of AZARGA (clinicaltrials.gov) -  Jun 20, 2013
P4, N=54, Completed,  Sponsor: Alcon Research
Recruiting --> Completed Recruiting --> Completed

|||||||||| New P4 trial: Comparison of Silicone and Porous Plate Ahmed Glaucoma Valves (clinicaltrials.gov) - Jun 19, 2013
P4, N=88, Recruiting, Sponsor: University of Virginia

|||||||||| Trial completion: A Study of the Rate of Progression of Glaucoma During a Follow-up Period of Two Years (clinicaltrials.gov) - Jun 18, 2013
P=N/A, N=315, Completed, Sponsor: Allergan
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Lumigan (bimatoprost) / Senju, AbbVie
New P4 trial:  An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension (clinicaltrials.gov) -  Jun 17, 2013
P4, N=94, Recruiting,  Sponsor: Allergan

|||||||||| New P2/3 trial: InnFocus MicroShunt Versus Trabeculectomy Study (clinicaltrials.gov) - Jun 17, 2013
P2/3, N=857, Recruiting, Sponsor: InnFocus Inc.

|||||||||| Enrollment closed: Safety and Performance of Miami InnFocus Drainage Implant (MIDI Arrow) Glaucoma Drainage Implant (clinicaltrials.gov) - Jun 16, 2013
P2, N=55, Active, not recruiting, Sponsor: InnFocus LLC
Active, not recruiting --> Completed Enrolling by invitation --> Active, not recruiting

||||||||||  Lumigan (bimatoprost) / Senju, AbbVie
Enrollment change:  A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With Glaucoma (clinicaltrials.gov) -  Jun 11, 2013
P3, N=120, Recruiting,  Sponsor: Allergan
Enrolling by invitation --> Active, not recruiting N=84 --> 120

|||||||||| Enrollment open: Study on the Impact of Ocular Anesthetic Procedures in Ocular Blood Flow (clinicaltrials.gov) - Jun 11, 2013
P=N/A, N=120, Recruiting, Sponsor: Universitaire Ziekenhuizen Leuven
N=84 --> 120 Active, not recruiting --> Recruiting

|||||||||| Enrollment open: Ocular Blood Flow in Glaucoma Patients - the Leuven Eye Study (clinicaltrials.gov) - Jun 11, 2013
P=N/A, N=120, Recruiting, Sponsor: Universitaire Ziekenhuizen Leuven
Active, not recruiting --> Recruiting Active, not recruiting --> Recruiting

|||||||||| Trial completion: Ocular Hypertension Treatment Study (OHTS) (clinicaltrials.gov) - Jun 11, 2013
P3, N=1636, Completed, Sponsor: Washington University School of Medicine
Active, not recruiting --> Recruiting Active, not recruiting --> Completed

||||||||||  bamosiran (SYL040012) / PharmaMar
Trial completion:  Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma (clinicaltrials.gov) -  Jun 6, 2013
P2, N=80, Completed,  Sponsor: Sylentis, S.A.
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Zioptan (tafluprost) / Santen, Merck (MSD)
Enrollment change:  Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002) (clinicaltrials.gov) -  Jun 5, 2013
P3, N=190, Completed,  Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed N=248 --> 190

||||||||||  Zioptan (tafluprost) / Santen, Merck (MSD)
Trial completion:  Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002) (clinicaltrials.gov) -  Jun 5, 2013
P3, N=190, Completed,  Sponsor: Merck Sharp & Dohme Corp.
N=248 --> 190 Active, not recruiting --> Completed

||||||||||  Omlonti (omidenepag isopropyl) / Santen, Ube Corp
New P2 trial:  Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) -  Jun 2, 2013
P2, N=91, Completed,  Sponsor: Santen Inc.

||||||||||  sepetaprost (DE-126) / Santen
Trial completion:  Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma (clinicaltrials.gov) -  May 30, 2013
P1, N=60, Completed,  Sponsor: Ono Pharma USA Inc
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Rocklatan (latanoprost/netarsudil) / Aerie Pharma
P2 data:  Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure (clinicaltrials.gov) -  May 28, 2013
P2, N=224, Completed,  Sponsor: Aerie Pharmaceuticals
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  bimatoprost/brimonidine / AbbVie
New P2 trial:  A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertension (clinicaltrials.gov) -  May 27, 2013
P2, N=112, Completed,  Sponsor: Allergan

||||||||||  RG4929 / Roche
Trial completion:  A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma (clinicaltrials.gov) -  May 22, 2013
P2, N=31, Completed,  Sponsor: Hoffmann-La Roche
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment change: A Placebo-Controlled Study of INS117548 Ophthalmic Solution in Subjects With Glaucoma (P08650) (clinicaltrials.gov) - May 21, 2013
P1, N=84, Completed, Sponsor: Merck Sharp & Dohme Corp.
Active, not recruiting --> Completed N=60 --> 84

|||||||||| Enrollment change, Surgery: COMPASS: Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery (clinicaltrials.gov) - May 20, 2013
P=N/A, N=897, Active, not recruiting, Sponsor: Transcend Medical, Inc.
N=60 --> 84 N=723 --> 897

|||||||||| Enrollment closed, Surgery: COMPASS: Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery (clinicaltrials.gov) - May 20, 2013
P=N/A, N=897, Active, not recruiting, Sponsor: Transcend Medical, Inc.
N=723 --> 897 Recruiting --> Active, not recruiting

||||||||||  Simbrinza (brinzolamide/brimonidine tartrate ophthalmic suspension) / Novartis
Enrollment change:  Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2% (clinicaltrials.gov) -  May 16, 2013
P3, N=1062, Completed,  Sponsor: Alcon Research
Recruiting --> Active, not recruiting N=690 --> 1062

|||||||||| Enrollment closed: CEI Van Outreach Screening Study (clinicaltrials.gov) - May 15, 2013
P=N/A, N=200, Active, not recruiting, Sponsor: Oregon Health and Science University
N=690 --> 1062 Recruiting --> Active, not recruiting

||||||||||  timolol maleate ophthalmic solution / Generic mfg.
Trial completion:  A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months (clinicaltrials.gov) -  May 14, 2013
P2, N=211, Completed,  Sponsor: Aerie Pharmaceuticals
Recruiting --> Active, not recruiting Active, not recruiting --> Completed

||||||||||  travoprost ophthalmic / Generic mfg.
Trial termination:  A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution (clinicaltrials.gov) -  May 12, 2013
P4, N=88, Terminated,  Sponsor: Alcon Research
Active, not recruiting --> Completed Active, not recruiting --> Terminated; Study objectives met

||||||||||  travoprost ophthalmic / Generic mfg.
Trial termination:  Study of TRAVATAN in Subjects With Iris Pigmentation Changes (clinicaltrials.gov) -  May 12, 2013
P4, N=336, Terminated,  Sponsor: Alcon Research
Active, not recruiting --> Terminated; Study objectives met Active, not recruiting --> Terminated; Study objectives met

||||||||||  travoprost ophthalmic / Generic mfg.
Enrollment change:  A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution (clinicaltrials.gov) -  May 12, 2013
P4, N=88, Terminated,  Sponsor: Alcon Research
Active, not recruiting --> Terminated; Study objectives met N=60 --> 88

||||||||||  travoprost ophthalmic / Generic mfg.
Enrollment change:  Study of TRAVATAN in Subjects With Iris Pigmentation Changes (clinicaltrials.gov) -  May 12, 2013
P4, N=336, Terminated,  Sponsor: Alcon Research
N=60 --> 88 N=250 --> 336

||||||||||  Lumigan (bimatoprost) / Senju, AbbVie
New P4 trial, Monotherapy:  A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan (clinicaltrials.gov) -  May 12, 2013
P4, N=2500, Recruiting,  Sponsor: Allergan

||||||||||  Catioprost (latanoprost emulsion) / Santen
Trial completion:  Safety and Efficacy Study of Catioprost (clinicaltrials.gov) -  May 12, 2013
P2, N=105, Completed,  Sponsor: Novagali Pharma
N=250 --> 336 Active, not recruiting --> Completed

|||||||||| Enrollment open: the Pops-titration Versus the Slow-coagulation Cyclophotocoagulation in Treatment of Refractory Glaucoma (clinicaltrials.gov) - May 5, 2013
P=N/A, N=90, Recruiting, Sponsor: Prince of Songkla University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting

||||||||||  Zioptan (tafluprost) / Santen, Merck (MSD)
Trial initiation date:  SAF-24H-IOP: Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) (clinicaltrials.gov) -  May 4, 2013
P4, N=40, Completed,  Sponsor: Azienda Ospedaliera Spedali Civili di Brescia
Not yet recruiting --> Recruiting Initiation date: Oct 2010 --> Mar 2011

||||||||||  Zioptan (tafluprost) / Santen, Merck (MSD)
Trial completion:  SAF-24H-IOP: Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) (clinicaltrials.gov) -  May 4, 2013
P4, N=40, Completed,  Sponsor: Azienda Ospedaliera Spedali Civili di Brescia
Initiation date: Oct 2010 --> Mar 2011 Active, not recruiting --> Completed

|||||||||| New P2 trial: Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging (clinicaltrials.gov) - May 2, 2013
P2, N=120, Not yet recruiting, Sponsor: Medical University of Vienna

||||||||||  travoprost punctal plug (OTX-TP) / Ocular Therap
New P1 trial:  Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma (clinicaltrials.gov) -  May 1, 2013
P1, N=60, Recruiting,  Sponsor: Ocular Therapeutix, Inc.

||||||||||  Combigan (brimonidine tartrate/timolol maleate) / AbbVie
Trial completion, Combination therapy:  Assessing the Efficacy and Tolerability of AZARGA (clinicaltrials.gov) -  May 1, 2013
P4, N=50, Completed,  Sponsor: Alcon Research
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Lumigan (bimatoprost) / Senju, AbbVie, Zioptan (tafluprost) / Santen, Merck (MSD)
Trial completion, Monotherapy:  Safety and Efficacy of Adding AZARGA (clinicaltrials.gov) -  May 1, 2013
P4, N=47, Completed,  Sponsor: Alcon Research
Recruiting --> Completed Recruiting --> Completed

||||||||||  dorzolamide / Generic mfg., timolol maleate ophthalmic solution / Generic mfg.
Clinical:  The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas Bubble (clinicaltrials.gov) -  Apr 29, 2013
P=N/A, N=20, Completed,  Sponsor: Brian Burke, MPH

|||||||||| New P4 trial, Surgery: Multicenter Post-Approval Study Of The Glaukos (clinicaltrials.gov) - Apr 24, 2013
P4, N=360, Recruiting, Sponsor: Glaukos Corporation

|||||||||| New trial, Surgery: Glaukos (clinicaltrials.gov) - Apr 24, 2013
P4, N=500, Recruiting, Sponsor: Glaukos Corporation

|||||||||| Trial termination: Effects of Selective Laser Trabeculoplasty (clinicaltrials.gov) - Apr 22, 2013
P4, N=30, Terminated, Sponsor: University of Kentucky
Recruiting --> Completed Recruiting --> Terminated; PI left the University