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89 Companies |
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65 Products |
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65 Products |
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50 Mechanisms of Action |
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813 Trials |
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63591 News |
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- ||| Enrollment open: Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-1) (clinicaltrials.gov) - Jun 28, 2016
P=N/A, N=249, Recruiting, Sponsor: Heidelberg Engineering GmbH
Not yet recruiting --> Recruiting
- ||| Enrollment open: Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3) (clinicaltrials.gov) - Jun 28, 2016
P=N/A, N=249, Recruiting, Sponsor: Heidelberg Engineering GmbH
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||| Eylea (aflibercept intravitreal) / Bayer, Regeneron
Enrollment closed: VEGA: Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients (clinicaltrials.gov) - Jun 27, 2016
P3, N=54, Active, not recruiting, Sponsor: Bayer
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Enrollment status: The American Glaucoma Society (AGS) Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS) (clinicaltrials.gov) - Jun 24, 2016
P4, N=280, Recruiting, Sponsor: Robert Feldman
Recruiting --> Active, not recruiting Enrolling by invitation --> Recruiting
- Trial primary completion date: The Effect of Scheduled Ripcord Removal on the Outcomes of Baerveldt 350 Implants (clinicaltrials.gov) - Jun 22, 2016
P=N/A, N=50, Recruiting, Sponsor: Duke University
Enrolling by invitation --> Recruiting Trial primary completion date: Apr 2016 --> Jan 2017
- New trial: The in Vivo Effect of Medical and Surgical Glaucoma Treatments on the Schlemm's Canal Micro-structure (clinicaltrials.gov) - Jun 21, 2016
P=N/A, N=440, Not yet recruiting, Sponsor: Sheba Medical Center
- |||| Simbrinza (brinzolamide/brimonidine tartrate ophthalmic suspension) / Novartis
Enrollment open: Safety and Efficacy of SIMBRINZA (clinicaltrials.gov) - Jun 20, 2016
P4, N=300, Recruiting, Sponsor: Alcon Research
Trial primary completion date: Apr 2016 --> Jan 2017 Not yet recruiting --> Recruiting
- | latanoprost liposomal (POLAT 001) / Avid Bioservices
Trial completion: Open Label Extension of LipoLat-CS202 (clinicaltrials.gov) - Jun 18, 2016
P=N/A, N=17, Completed, Sponsor: Peregrine Ophthalmic
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- New trial: Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle Glaucoma (clinicaltrials.gov) - Jun 18, 2016
P=N/A, N=200, Completed, Sponsor: Lv Yingjuan
- | mitomycin / Generic mfg.
New P2 trial, Surgery: AMCT: Ahmed Glaucoma Valve Surgery With Mitomycin-C (clinicaltrials.gov) - Jun 18, 2016
P2, N=100, Not yet recruiting, Sponsor: University of California, San Francisco
- |||||||||| latanoprost / Generic mfg.
New P3 trial, Head-to-Head, Compliance: Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno (clinicaltrials.gov) - Jun 16, 2016
P3, N=100, Recruiting, Sponsor: Laboratorios Sophia S.A de C.V.
- Zioptan (tafluprost) / Santen, Merck (MSD)
New P4 trial: 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy (clinicaltrials.gov) - Jun 16, 2016
P4, N=43, Completed, Sponsor: Aristotle University Of Thessaloniki
- Enrollment open: POSAG: Prevalence of Obstructive Sleep Apnoea in Glaucoma (clinicaltrials.gov) - Jun 15, 2016
P=N/A, N=480, Recruiting, Sponsor: Papworth Hospital NHS Foundation Trust
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | travoprost ophthalmic / Generic mfg.
New P4 trial: Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Jun 11, 2016
P4, N=76, Not yet recruiting, Sponsor: Universit
- Trial completion, Trial primary completion date: Does Oral Acetaminophen Lower Intraocular Pressure? (clinicaltrials.gov) - Jun 10, 2016
P0, N=11, Completed, Sponsor: Johns Hopkins University
Not yet recruiting --> Recruiting Recruiting --> Completed | Trial primary completion date: Jan 2016 --> May 2016
- timolol maleate ophthalmic solution / Generic mfg.
Enrollment open: Evaluation of a New Method for Instilling Eye Drops (clinicaltrials.gov) - Jun 9, 2016
P0, N=60, Recruiting, Sponsor: University of Waterloo
Recruiting --> Completed | Trial primary completion date: Jan 2016 --> May 2016 Not yet recruiting --> Recruiting
- ||||| latanoprost / Generic mfg.
New P4 trial: A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma (clinicaltrials.gov) - Jun 9, 2016
P4, N=60, Recruiting, Sponsor: Dr. David Yan
- ||||| New P4 trial: Glaucoma Treatment Using Focused Ultrasound in Open Angle Glaucoma Patients (clinicaltrials.gov) - Jun 2, 2016
P4, N=80, Not yet recruiting, Sponsor: EyeTechCare
- Enrollment open, Trial initiation date, Trial primary completion date: AUREVI 1: AUgmented REality for the Visually Impaired - Part 1 (clinicaltrials.gov) - Jun 1, 2016
P=N/A, N=15, Recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Initiation date: Oct 2016 --> May 2016 | Trial primary completion date: Oct 2017 --> May 2017
- |||| Simbrinza (brinzolamide/brimonidine tartrate ophthalmic suspension) / Novartis
Enrollment open: 24-hr Intraocular Pressure Control With SIMBRINZA (clinicaltrials.gov) - May 31, 2016
P4, N=142, Recruiting, Sponsor: Alcon Research
Not yet recruiting --> Recruiting | Initiation date: Oct 2016 --> May 2016 | Trial primary completion date: Oct 2017 --> May 2017 Not yet recruiting --> Recruiting
- New trial: A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract Extraction (clinicaltrials.gov) - May 27, 2016
P=N/A, N=150, Not yet recruiting, Sponsor: New World Medical, Inc.
- ||| New trial: Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-1) (clinicaltrials.gov) - May 27, 2016
P=N/A, N=249, Not yet recruiting, Sponsor: Heidelberg Engineering GmbH
- ||| New trial: Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3) (clinicaltrials.gov) - May 27, 2016
P=N/A, N=249, Not yet recruiting, Sponsor: Heidelberg Engineering GmbH
- Trial primary completion date: Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration (clinicaltrials.gov) - May 26, 2016
P1/2, N=16, Enrolling by invitation, Sponsor: Central Clinical Hospital with Outpatient Health Center of Business Administration for the President of Russian Federati
Not yet recruiting --> Recruiting Trial primary completion date: Nov 2016 --> Nov 2017
- latanoprost / Generic mfg.
Biomarker, Enrollment closed, Trial primary completion date: Glaucoma Biomarkers (clinicaltrials.gov) - May 19, 2016
P=N/A, N=150, Active, not recruiting, Sponsor: University of Michigan
Trial primary completion date: Nov 2016 --> Nov 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Dec 2016
- ||||| Rocklatan (latanoprost/netarsudil) / Aerie Pharma, Rhopressa (netarsudil) / Aerie Pharma
Clinical: Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension (clinicaltrials.gov) - May 18, 2016
P3, N=690, Active, not recruiting, Sponsor: Aerie Pharmaceuticals
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Active, not recruiting
- Lumigan (bimatoprost) / Senju, AbbVie
New trial: Primary Glaucoma Treatment Trial in Kenya and South Africa - SLT vs. Medication (clinicaltrials.gov) - May 18, 2016
P=N/A, N=400, Recruiting, Sponsor: University College, London
- New trial: Pressure Difference Between Brain and Eye: a Possible Cause to Normal Tension Glaucoma. (clinicaltrials.gov) - May 18, 2016
P=N/A, N=20, Recruiting, Sponsor: Ume
- New trial: Clinical and Molecular Studies in Families With Inherited Eye Disease (clinicaltrials.gov) - May 13, 2016
P=N/A, N=5000, Recruiting, Sponsor: National Eye Institute (NEI)
- New trial: Novel Portable Diagnostic Device for Automatic Detection of Relative Afferent Pupillary Defect (clinicaltrials.gov) - May 13, 2016
P=N/A, N=44, Active, not recruiting, Sponsor: Mashhad University of Medical Sciences
- |||| Lumigan (bimatoprost) / Senju, AbbVie, Zioptan (tafluprost) / Santen, Merck (MSD)
Enrollment open: SPORTII: Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml (clinicaltrials.gov) - May 12, 2016
P4, N=67, Recruiting, Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- ||||| Simbrinza (brinzolamide/brimonidine tartrate ophthalmic suspension) / Novartis
New P4 trial: 24-hr Intraocular Pressure Control With SIMBRINZA (clinicaltrials.gov) - May 12, 2016
P4, N=142, Not yet recruiting, Sponsor: Alcon Research
- Avastin (bevacizumab) / Roche
New P3 trial, Surgery: RAFTS: The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery (clinicaltrials.gov) - May 10, 2016
P3, N=30, Not yet recruiting, Sponsor: Moorfields Eye Hospital NHS Foundation Trust
- Enrollment closed, Trial primary completion date: Alcon (clinicaltrials.gov) - May 9, 2016
P=N/A, N=45, Active, not recruiting, Sponsor: Alcon Research
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016
- New trial: Aqueous Humor Dynamics and Hypertensive Uveitis (clinicaltrials.gov) - May 6, 2016
P=N/A, N=90, Recruiting, Sponsor: Guy's and St Thomas' NHS Foundation Trust
- H.P. Acthar Gel (repository corticotropin injection) / Mallinckrodt
New P4 trial, Adverse events: Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients (clinicaltrials.gov) - May 6, 2016
P4, N=6, Not yet recruiting, Sponsor: Tampa Bay Uveitis Center, LLC
- |||||| Rocklatan (latanoprost/netarsudil) / Aerie Pharma, Rhopressa (netarsudil) / Aerie Pharma
Clinical: Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - May 2, 2016
P3, N=690, Recruiting, Sponsor: Aerie Pharmaceuticals
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016 Not yet recruiting --> Recruiting
- Enrollment closed, Trial primary completion date, Adherence: SIGMA: Study on Incentives for Glaucoma Medications Adherence (clinicaltrials.gov) - May 2, 2016
P=N/A, N=100, Active, not recruiting, Sponsor: Duke-NUS Graduate Medical School
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jan 2017
- New trial: Evaluation of Blood Flow Characteristics in Glaucoma Using Optical Coherence Tomography Angiography (OCT-A). (clinicaltrials.gov) - May 2, 2016
P=N/A, N=500, Recruiting, Sponsor: Swiss Vision Network
- pilocarpine / Generic mfg.
New trial: The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure (clinicaltrials.gov) - Apr 28, 2016
P=N/A, N=30, Not yet recruiting, Sponsor: University of Colorado, Denver
- ||||| timolol maleate ophthalmic solution / Generic mfg., travoprost ophthalmic / Generic mfg.
New P2 trial: Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution (clinicaltrials.gov) - Apr 28, 2016
P2, N=300, Recruiting, Sponsor: Glaukos Corporation
- ||| SAR366234 / Sanofi
Trial completion, Enrollment change: 28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension (clinicaltrials.gov) - Apr 27, 2016
P1, N=54, Completed, Sponsor: Sanofi
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jan 2017 Active, not recruiting --> Completed | N=75 --> 54
- | Trial completion, Enrollment change: Comparison of Optic Nerve Head and Retinal Nerve Fiber Layer Parameters Derived From Two Different Methods of Scan Alignment (clinicaltrials.gov) - Apr 26, 2016
P=N/A, N=48, Completed, Sponsor: Heidelberg Engineering GmbH
Active, not recruiting --> Completed | N=75 --> 54 Not yet recruiting --> Completed | N=40 --> 48
- Enrollment open: The American Glaucoma Society (AGS) Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS) (clinicaltrials.gov) - Apr 25, 2016
P4, N=280, Enrolling by invitation, Sponsor: Robert Feldman
Not yet recruiting --> Completed | N=40 --> 48 Not yet recruiting --> Enrolling by invitation
- latanoprost liposomal (POLAT 001) / Avid Bioservices
Enrollment closed, Enrollment change: Open Label Extension of LipoLat-CS202 (clinicaltrials.gov) - Apr 22, 2016
P=N/A, N=17, Active, not recruiting, Sponsor: Peregrine Ophthalmic
Not yet recruiting --> Enrolling by invitation Recruiting --> Active, not recruiting | N=54 --> 17
- |||| latanoprost liposomal (POLAT 001) / Avid Bioservices
Trial completion: POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma (clinicaltrials.gov) - Apr 22, 2016
P2, N=81, Completed, Sponsor: Peregrine Ophthalmic
Recruiting --> Active, not recruiting | N=54 --> 17 Active, not recruiting --> Completed
- Trial primary completion date: DSLT: Direct Application of Selective Laser Trabeculoplasty in Open Angle Glaucoma (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=20, Recruiting, Sponsor: Sheba Medical Center
Active, not recruiting --> Completed Trial primary completion date: Jul 2015 --> Nov 2016
- Lucentis (ranibizumab) / Roche, Novartis
Phase classification, Surgery: OCTOPUS: Use of Ranibizumab With Mitomycin C During Trabeculectomy (clinicaltrials.gov) - Apr 20, 2016
P1/2, N=30, Completed, Sponsor: University of Colorado, Denver
Trial primary completion date: Jul 2015 --> Nov 2016 Phase classification: P=N/A --> P1/2
- mitomycin / Generic mfg.
New trial: Mitomycin C Trabeculectomy Trial for Glaucoma in Ethiopia (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=100, Recruiting, Sponsor: Francis I. Proctor Foundation
- Eylea (aflibercept intravitreal) / Bayer, Regeneron
Trial primary completion date: Use of Intravitreal Aflibercept Injection for Neovascular Glaucoma (clinicaltrials.gov) - Apr 19, 2016
P=N/A, N=7, Active, not recruiting, Sponsor: University of Colorado, Denver
Phase classification: P=N/A --> P1/2 Trial primary completion date: Mar 2016 --> Dec 2016