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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- || Takecab (vonoprazan) / Takeda, Phathom Pharma
New P3 trial: Efficacy of TAK-438 Compared to Placebo in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (clinicaltrials.gov) - Nov 16, 2011
P3, N=827, Completed, Sponsor: Takeda Pharmaceutical Company Limited
- ||||| Herceptin (trastuzumab) / Roche
New P2 trial, Combination therapy, Metastases: HerFLOT: Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach (clinicaltrials.gov) - Nov 14, 2011
P2, N=53, Active, not recruiting, Sponsor: AIO-Studien-gGmbH
- HEOR: Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer (clinicaltrials.gov) - Nov 13, 2011
P=N/A, N=100, Recruiting, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
- Enrollment change, Endobronchial ultrasound: CT0003: Endobronchial Ultrasound (EBUS) for Nodal Staging in Esophageal Cancer (clinicaltrials.gov) - Nov 9, 2011
P=N/A, N=50, Completed, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
N=40 --> 50
- | cisplatin / Generic mfg., capecitabine / Generic mfg.
New P2 trial, Metastases: Phase II Trial of XP Versus XG in Advanced Esophageal Squamous Cell Carcinoma (clinicaltrials.gov) - Nov 9, 2011
P2, N=94, Recruiting, Sponsor: Samsung Medical Center
- Trial completion, Endobronchial ultrasound: CT0003: Endobronchial Ultrasound (EBUS) for Nodal Staging in Esophageal Cancer (clinicaltrials.gov) - Nov 9, 2011
P=N/A, N=50, Completed, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
N=40 --> 50 Recruiting --> Completed
- Trial completion: Swallowing Training in Parkinson`s Disease (clinicaltrials.gov) - Nov 6, 2011
P=N/A, N=17, Completed, Sponsor: Federal University of Bahia
Recruiting --> Completed Recruiting --> Completed
- docetaxel / Generic mfg., gemcitabine / Generic mfg.
New P2 trial, Metastases: Study of Docetaxel and Gemcitabine in Metastatic Esophageal Squamous Cell Cancer (clinicaltrials.gov) - Nov 6, 2011
P2, N=32, Recruiting, Sponsor: Samsung Medical Center
- Enrollment closed, HEOR: Pre-treatment Exercises Versus Post-treatment Exercises for Dysphagia (clinicaltrials.gov) - Oct 31, 2011
P=N/A, N=90, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Recruiting --> Completed Recruiting --> Active, not recruiting
- |||||||||| esomeprazole / Generic mfg.
New P3 trial, Head-to-Head: Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC (clinicaltrials.gov) - Oct 30, 2011
P3, N=188, Not yet recruiting, Sponsor: Eurofarma Laboratorios S.A.
- Enrollment change: B-Receptor Signaling in Cardiomyopathy (clinicaltrials.gov) - Oct 30, 2011
P=N/A, N=99, Completed, Sponsor: Daniel Bernstein
Recruiting --> Active, not recruiting N=300 --> 99
- Trial completion: B-Receptor Signaling in Cardiomyopathy (clinicaltrials.gov) - Oct 30, 2011
P=N/A, N=99, Completed, Sponsor: Daniel Bernstein
N=300 --> 99 Recruiting --> Completed
- erlotinib / Generic mfg.
Trial completion, Metastases: Erlotinib and Radiation Therapy in Treating Older Patients With Stage I, Stage II, Stage III, or Stage IV Esophageal Cancer (clinicaltrials.gov) - Oct 27, 2011
P2, N=17, Completed, Sponsor: Roswell Park Cancer Institute
Recruiting --> Completed Active, not recruiting --> Completed
- | fluticasone / Generic mfg.
Trial completion: Topical Steroid Treatment for Eosinophilic Esophagitis (clinicaltrials.gov) - Oct 25, 2011
P2, N=42, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Glypressin (terlipressin) / Ferring
Trial completion: Follow-up of Glypressin (Terlipressin) Clinical Efficacy in the Treatment of Bleeding Oesophageal Varices (clinicaltrials.gov) - Oct 24, 2011
P=N/A, N=20, Completed, Sponsor: Ferring Pharmaceuticals
Active, not recruiting --> Completed Recruiting --> Completed
- |||||||||| Takecab (vonoprazan) / Takeda, Phathom Pharma
New P3 trial: Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis (clinicaltrials.gov) - Oct 23, 2011
P3, N=607, Completed, Sponsor: Takeda
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion, Metastases: Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors (clinicaltrials.gov) - Oct 18, 2011
P1, N=35, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment open: Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection (clinicaltrials.gov) - Oct 16, 2011
P4, N=64, Recruiting, Sponsor: University Hospital, Linkoeping
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- |||||||||| Takecab (vonoprazan) / Takeda, Phathom Pharma
New P3 trial: Long-Term Safety Study of TAK-438 in the Maintenance Treatment of Healed Erosive Esophagitis (clinicaltrials.gov) - Oct 13, 2011
P3, N=305, Completed, Sponsor: Takeda
- || Takecab (vonoprazan) / Takeda, Phathom Pharma
New P3 trial: Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Erosive Esophagitis (clinicaltrials.gov) - Oct 13, 2011
P3, N=409, Completed, Sponsor: Takeda Pharmaceutical Company Limited
- | Enrollment change: Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia (clinicaltrials.gov) - Oct 11, 2011
P3, N=200, Completed, Sponsor: International Atomic Energy Agency
Not yet recruiting --> Recruiting N=420 --> 200
- | Trial completion: Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia (clinicaltrials.gov) - Oct 11, 2011
P3, N=200, Completed, Sponsor: International Atomic Energy Agency
N=420 --> 200 Recruiting --> Completed
- |||||||||| New P3 trial: Efficacy and Safety of Alginos Oral Suspension to Treat Laryngopharyngeal Reflux (clinicaltrials.gov) - Oct 10, 2011
P3, N=70, Recruiting, Sponsor: TTY Biopharm
- Trial completion: Evaluation of a Miniaturized Microscope Device for the Detection of Barrett's Neoplasia: A Pilot Study (clinicaltrials.gov) - Oct 5, 2011
P0, N=40, Completed, Sponsor: Anandasabapathy, Sharmila, M.D.
Recruiting --> Completed Recruiting --> Completed
- | metformin / Generic mfg.
New P2 trial: Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus (clinicaltrials.gov) - Oct 4, 2011
P2, N=86, Active, not recruiting, Sponsor: National Cancer Institute (NCI)
- | Enrollment change: A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Reflux Disease (clinicaltrials.gov) - Oct 3, 2011
P3, N=26, Completed, Sponsor: Eisai Inc.
Recruiting --> Completed N=20 --> 26
- azithromycin / Generic mfg.
New P2 trial: Effect of Azithromycin on Oesophageal Hypomotility (clinicaltrials.gov) - Sep 29, 2011
P2, N=34, Not yet recruiting, Sponsor: JAFAR JAFARI
- || New P2/3 trial, Surgery: Prevention of Post-operative Pneumonia (POPP) (clinicaltrials.gov) - Sep 29, 2011
P2/3, N=330, Recruiting, Sponsor: Washington University School of Medicine
- Enrollment open: Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasia (clinicaltrials.gov) - Sep 29, 2011
P0, N=50, Recruiting, Sponsor: Anandasabapathy, Sharmila, M.D.
N=20 --> 26 Not yet recruiting --> Recruiting
- Enrollment change: Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors (clinicaltrials.gov) - Sep 28, 2011
P=N/A, N=49, Completed, Sponsor: University of Utah
Not yet recruiting --> Recruiting N=40 --> 49
- Trial completion: Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors (clinicaltrials.gov) - Sep 28, 2011
P=N/A, N=49, Completed, Sponsor: University of Utah
N=40 --> 49 Active, not recruiting --> Completed
- Clinical: Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia (clinicaltrials.gov) - Sep 20, 2011
P=N/A, N=100, Recruiting, Sponsor: Winthrop University Hospital
- New P1 trial, Biopsy: Optical Frequency Domain Imaging (OFDI) Surveillance and Image Guided Biopsy of the Esophagus (clinicaltrials.gov) - Sep 19, 2011
P1, N=24, Recruiting, Sponsor: Massachusetts General Hospital
- ||||||| pantoprazole / Generic mfg.
Trial completion: Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease (clinicaltrials.gov) - Sep 19, 2011
P3, N=154, Completed, Sponsor: Ahn-Gook Pharmaceuticals Co.,Ltd
Active, not recruiting --> Completed Enrolling by invitation --> Completed
- Trial completion: A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of Pumosetrag in Patients With Gastroesophageal Reflux Disease (GERD) (clinicaltrials.gov) - Sep 19, 2011
P2a, N=0, Completed, Sponsor: Edusa Pharmaceuticals, Inc.
Enrolling by invitation --> Completed Recruiting --> Completed
- Trial withdrawal: Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD (clinicaltrials.gov) - Sep 18, 2011
P2, N=20, Withdrawn, Sponsor: University of Alberta
Recruiting --> Completed Suspended --> Withdrawn
- | cisplatin / Generic mfg., docetaxel / Generic mfg.
Biomarker, Enrollment change: PANCHO: p53-Adjusted Neoadjuvant Chemotherapy for Potentially Resectable Esophageal Cancer (clinicaltrials.gov) - Sep 7, 2011
P3, N=170, Completed, Sponsor: Daniela Kandioler
Suspended --> Withdrawn N=84 --> 170
- 5-fluorouracil / Generic mfg., oxaliplatin / Generic mfg., docetaxel / Generic mfg.
Biomarker, Trial completion, HEOR, Metastases: Oxaliplatin and 5-Fluorouracil With or Without Docetaxel in Elderly Patients (>65 y) With Stomach and Esophagus Cancer (clinicaltrials.gov) - Aug 28, 2011
P2, N=143, Completed, Sponsor: Krankenhaus Nordwest
N=84 --> 170 Active, not recruiting --> Completed
- Clinical: Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease (clinicaltrials.gov) - Aug 18, 2011
P=N/A, N=100, Not yet recruiting, Sponsor: Federal University of Bahia
- Enrollment open: CoFAR5: Eosinophilic Esophagitis Databank (clinicaltrials.gov) - Aug 15, 2011
P=N/A, N=600, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- cisplatin / Generic mfg., paclitaxel / Generic mfg., gefitinib / Generic mfg.
Trial termination, Surgery, Metastases: Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery (clinicaltrials.gov) - Aug 14, 2011
P2, N=36, Terminated, Sponsor: Sidney Kimmel Comprehensive Cancer Center
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated; Closed due to early stopping rule-Low accrual
- New P1 trial: DysphagCerv: Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions (clinicaltrials.gov) - Aug 14, 2011
P1, N=100, Recruiting, Sponsor: University of Ioannina
- oxaliplatin / Generic mfg., irinotecan / Generic mfg.
Trial completion, Metastases: Oxaliplatin and Irinotecan in Recurrent or Metastatic Esophageal and Gastroesophageal (GE) Junction Carcinoma (clinicaltrials.gov) - Aug 14, 2011
P2, N=4, Completed, Sponsor: University of California, Irvine
Active, not recruiting --> Terminated; Closed due to early stopping rule-Low accrual Active, not recruiting --> Completed
- Trial withdrawal, Surgery: STRETCH: Study of Endoscopic Versus Open Surgery for Urinary Reflux (clinicaltrials.gov) - Aug 10, 2011
P=N/A, N=0, Withdrawn, Sponsor: Children's Hospital Boston
Active, not recruiting --> Completed Recruiting --> Withdrawn
- Enrollment change, Surgery: STRETCH: Study of Endoscopic Versus Open Surgery for Urinary Reflux (clinicaltrials.gov) - Aug 10, 2011
P=N/A, N=0, Withdrawn, Sponsor: Children's Hospital Boston
Recruiting --> Withdrawn N=200 --> 0
- | New P4 trial: Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection (clinicaltrials.gov) - Aug 10, 2011
P4, N=64, Recruiting, Sponsor: University Hospital, Linkoeping