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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- Trial completion: Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique (clinicaltrials.gov) - Sep 30, 2012
P=N/A, N=141, Completed, Sponsor: University of California, San Francisco
Recruiting --> Completed
- ||| Cyramza (ramucirumab) / Eli Lilly
Enrollment closed, Metastases: A Study of Ramucirumab in Participants With Gastric, Esophageal, and Gastroesophageal Cancer (clinicaltrials.gov) - Sep 27, 2012
P2, N=166, Active, not recruiting, Sponsor: Eli Lilly and Company
Recruiting --> Completed Recruiting --> Active, not recruiting
- Enrollment change: A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia (clinicaltrials.gov) - Sep 24, 2012
P2, N=10, Completed, Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting --> Active, not recruiting N=20 --> 10
- Trial withdrawal: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Gastrointestinal Cancer (clinicaltrials.gov) - Sep 12, 2012
P1, N=0, Withdrawn, Sponsor: University of California, San Francisco
N=20 --> 10 Completed --> Withdrawn
- cisplatin / Generic mfg., gefitinib / Generic mfg., irinotecan / Generic mfg.
Trial termination, Surgery: Gefitinib, Cisplatin, Irinotecan, and Radiation Therapy Before Surgery in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery (clinicaltrials.gov) - Sep 12, 2012
P1/2, N=6, Terminated, Sponsor: University of California, San Francisco
Completed --> Withdrawn Active, not recruiting --> Terminated; low enrollment
- cisplatin / Generic mfg., gefitinib / Generic mfg., irinotecan / Generic mfg.
Enrollment change, Surgery: Gefitinib, Cisplatin, Irinotecan, and Radiation Therapy Before Surgery in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery (clinicaltrials.gov) - Sep 12, 2012
P1/2, N=6, Terminated, Sponsor: University of California, San Francisco
Active, not recruiting --> Terminated; low enrollment N=20 --> 6
- Trial completion, Immunomodulating: INEC Study: Immuno-modulating Enteral Nutrition in Cancer (clinicaltrials.gov) - Sep 12, 2012
P4, N=250, Completed, Sponsor: University Hospital, Clermont-Ferrand
N=20 --> 6 Recruiting --> Completed
- Clinical: AIMEE: Allergy Immunotherapy in the Management of Eosinophilic Esophagitis (clinicaltrials.gov) - Sep 11, 2012
P=N/A, N=27, Not yet recruiting, Sponsor: United States Naval Medical Center, San Diego
- Trial termination: Domperidone for Relief of Gastrointestinal Disorders (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=42, Terminated, Sponsor: Carle Physician Group
Recruiting --> Completed Active, not recruiting --> Terminated; PI withdrew due to increased responsibilities in clinical department.
- Enrollment change: Domperidone for Relief of Gastrointestinal Disorders (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=42, Terminated, Sponsor: Carle Physician Group
Active, not recruiting --> Terminated; PI withdrew due to increased responsibilities in clinical department. N=80 --> 42
- Clinical data: Dysphagia Assessment in Acute Ischemic Stroke Using High-resolution Manometry (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=293, Completed, Sponsor: The Catholic University of Korea
- Enrollment open: Stroke Swallowing Screening Tool Validation (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=305, Recruiting, Sponsor: Department of Veterans Affairs
N=80 --> 42 Not yet recruiting --> Recruiting
- Trial completion, MRI: Measurement of Gastric Secretion by MRI Under Inhibition by ProtonPump Inhibitors in Healthy Subjects & in GERD Patients (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=24, Completed, Sponsor: University of Zurich
Not yet recruiting --> Recruiting Recruiting --> Completed
- Clinical: SIRUP: Stretta In Reflux Uncontrolled by IPP (clinicaltrials.gov) - Sep 6, 2012
P=N/A, N=60, Recruiting, Sponsor: Nantes University Hospital
- cisplatin / Generic mfg., irinotecan / Generic mfg.
Enrollment closed, Surgery: Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery (clinicaltrials.gov) - Sep 5, 2012
P2, N=90, Active, not recruiting, Sponsor: Cancer and Leukemia Group B
Recruiting --> Completed Recruiting --> Active, not recruiting
- Trial withdrawal: Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation Therapy (clinicaltrials.gov) - Sep 4, 2012
P=N/A, N=0, Withdrawn, Sponsor: M.D. Anderson Cancer Center
Recruiting --> Active, not recruiting Not yet recruiting --> Withdrawn
- Enrollment change: Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation Therapy (clinicaltrials.gov) - Sep 4, 2012
P=N/A, N=0, Withdrawn, Sponsor: M.D. Anderson Cancer Center
Not yet recruiting --> Withdrawn N=50 --> 0
- Trial completion: Effect Of Piperine In Patients With Oropharyngeal Dysphagia (clinicaltrials.gov) - Sep 4, 2012
P=N/A, N=0, Completed, Sponsor: Hospital de Matar
N=50 --> 0 Recruiting --> Completed
- |||||| esomeprazole / Generic mfg.
Enrollment open: Compare D961H 20 mg Bid and 20 mg qd in Patients With Refractory Reflux Esophagitis (Inflammation of Lower Esophagus) (clinicaltrials.gov) - Aug 29, 2012
P3, N=700, Recruiting, Sponsor: AstraZeneca
Recruiting --> Completed Not yet recruiting --> Recruiting
- amiloride hydrochloride / Generic mfg.
Enrollment change: Do Acid Sensing Ion Channels Contribute to Heartburn? (clinicaltrials.gov) - Aug 27, 2012
P1, N=24, Completed, Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting --> Recruiting N=16 --> 24
- Dexilant (dexlansoprazole) / Takeda
Trial completion: Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn (clinicaltrials.gov) - Aug 27, 2012
P4, N=40, Completed, Sponsor: University of North Carolina, Chapel Hill
N=16 --> 24 Recruiting --> Completed
- amiloride hydrochloride / Generic mfg.
Trial completion: Do Acid Sensing Ion Channels Contribute to Heartburn? (clinicaltrials.gov) - Aug 27, 2012
P1, N=24, Completed, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Completed Active, not recruiting --> Completed
- remifentanil / Generic mfg.
Enrollment change: Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration (clinicaltrials.gov) - Aug 20, 2012
P4, N=25, Completed, Sponsor: University Hospital Orebro
Active, not recruiting --> Completed N=14 --> 25
- remifentanil / Generic mfg.
Trial completion: Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration (clinicaltrials.gov) - Aug 20, 2012
P4, N=25, Completed, Sponsor: University Hospital Orebro
N=14 --> 25 Recruiting --> Completed
- |||||||||| esomeprazole / Generic mfg.
New P3 trial: Compare D961H 20 mg Bid and 20 mg qd in Patients With Refractory Reflux Esophagitis (Inflammation of Lower Esophagus) (clinicaltrials.gov) - Aug 19, 2012
P3, N=700, Recruiting, Sponsor: AstraZeneca
- Enrollment closed: FLT PET/CT for Staging, Target Definition and Assessment of Response to Therapy in Patients With Esophageal Cancer (clinicaltrials.gov) - Aug 14, 2012
P=N/A, N=5, Active, not recruiting, Sponsor: Dana-Farber Cancer Institute
Recruiting --> Completed Recruiting --> Active, not recruiting
- | Trial suspension, Metastases: Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction (clinicaltrials.gov) - Aug 13, 2012
P2, N=96, Suspended, Sponsor: North Central Cancer Treatment Group
Recruiting --> Active, not recruiting Recruiting --> Suspended
- cisplatin / Generic mfg., pemetrexed / Generic mfg.
Trial initiation date, Metastases: Pemetrexed, Cisplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer (clinicaltrials.gov) - Aug 13, 2012
P1, N=15, Recruiting, Sponsor: University of Arizona
Recruiting --> Suspended Initiation date: Aug 2007 --> Feb 2008
- cisplatin / Generic mfg., pemetrexed / Generic mfg.
Enrollment change, Metastases: Pemetrexed, Cisplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer (clinicaltrials.gov) - Aug 13, 2012
P1, N=15, Recruiting, Sponsor: University of Arizona
Initiation date: Aug 2007 --> Feb 2008 N=34 --> 15
- Trial completion, Surgery: Do Patients Who Have Had Surgery for Achalasia Suffer From Reflux (clinicaltrials.gov) - Aug 13, 2012
P=N/A, N=100, Completed, Sponsor: Kenneth Luberice
N=34 --> 15 Recruiting --> Completed
- Trial termination, Metastases: A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer (clinicaltrials.gov) - Aug 9, 2012
P3, N=4, Terminated, Sponsor: Weill Medical College of Cornell University
Recruiting --> Completed Recruiting --> Terminated; Closed due to slow patient accrual.
- Enrollment change, Metastases: A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer (clinicaltrials.gov) - Aug 9, 2012
P3, N=4, Terminated, Sponsor: Weill Medical College of Cornell University
Recruiting --> Terminated; Closed due to slow patient accrual. N=102 --> 4
- | Trial completion: Incidence and Patterns of Nausea/Vomiting With Combined Chemotherapy and Radiation (clinicaltrials.gov) - Aug 8, 2012
P=N/A, N=40, Completed, Sponsor: Thomas Jefferson University
N=102 --> 4 Recruiting --> Completed
- | omeprazole / Generic mfg.
New P2 trial: OMEPRAZOLE-1: Optimal Dosing of Omeprazole in Neonates (clinicaltrials.gov) - Aug 2, 2012
P2, N=55, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
- | simvastatin / Generic mfg.
Trial initiation date: Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding (clinicaltrials.gov) - Jul 31, 2012
P3, N=158, Recruiting, Sponsor: Juan A. Arnaiz
Recruiting --> Completed Initiation date: May 2010 --> Nov 2010
- |||| dexlansoprazole / Generic mfg.
Enrollment open: Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents (clinicaltrials.gov) - Jul 31, 2012
P2, N=60, Recruiting, Sponsor: Takeda
Initiation date: May 2010 --> Nov 2010 Not yet recruiting --> Recruiting
- ||| esomeprazole / Generic mfg.
Enrollment change: Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms (clinicaltrials.gov) - Jul 26, 2012
P2, N=52, Completed, Sponsor: Vecta Ltd.
Not yet recruiting --> Recruiting N=80 --> 52
- |||| esomeprazole / Generic mfg.
Trial completion: Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms (clinicaltrials.gov) - Jul 26, 2012
P2, N=52, Completed, Sponsor: Vecta Ltd.
N=80 --> 52 Active, not recruiting --> Completed
- | New P4 trial: Evaluation of Two Different Thickening Products in Patients With Dysphagia (clinicaltrials.gov) - Jul 25, 2012
P4, N=100, Completed, Sponsor: University of California, Davis
- Trial completion: PETREC: Positron Emission Tomography/Computed Tomography (PET/CT) for the Diagnosis of Recurrent Cancer: a Feasibility Study (clinicaltrials.gov) - Jul 25, 2012
P=N/A, N=101, Completed, Sponsor: Ontario Clinical Oncology Group (OCOG)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Vizimpro (dacomitinib) / Pfizer
Enrollment open, Metastases: A Phase II Trial of PF-00299804 in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus (clinicaltrials.gov) - Jul 23, 2012
P2, N=49, Recruiting, Sponsor: Yonsei University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- || Enrollment closed: HALO Patient Registry: Ablation of Barrett's Esophagus (clinicaltrials.gov) - Jul 23, 2012
P=N/A, N=10000, Active, not recruiting, Sponsor: Covidien, GI Solutions
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Avastin (bevacizumab) / Roche
Enrollment change, Surgery: Phase II Trial for Patients With Loco-Regional Esophageal Carcinoma (clinicaltrials.gov) - Jul 23, 2012
P2, N=6, Active, not recruiting, Sponsor: University of Michigan Cancer Center
Recruiting --> Active, not recruiting N=63 --> 6
- Trial completion, Biopsy: Analysis of Biopsies From the Upper Gastrointestinal Tract (clinicaltrials.gov) - Jul 22, 2012
P=N/A, N=600, Completed, Sponsor: Medical University of Graz
N=63 --> 6 Recruiting --> Completed
- ||||| Dexilant (dexlansoprazole) / Takeda
New P2 trial: Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescents (clinicaltrials.gov) - Jul 15, 2012
P2, N=104, Completed, Sponsor: Takeda
- ||||| dexlansoprazole / Generic mfg.
New P2 trial: Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents (clinicaltrials.gov) - Jul 15, 2012
P2, N=60, Recruiting, Sponsor: Takeda
- nortriptyline / Generic mfg.
Trial completion: NORGERD: Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients (clinicaltrials.gov) - Jul 13, 2012
P3, N=20, Completed, Sponsor: Universidade de Passo Fundo
Recruiting --> Completed Enrolling by invitation --> Completed
- carboplatin / Generic mfg., fluorouracil topical / Generic mfg., capecitabine / Generic mfg.
Trial termination, Metastases: Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer (clinicaltrials.gov) - Jul 12, 2012
P1, N=4, Terminated, Sponsor: Stanford University
Enrolling by invitation --> Completed Completed --> Terminated; low accrual
- carboplatin / Generic mfg., fluorouracil topical / Generic mfg., capecitabine / Generic mfg.
Enrollment change, Metastases: Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer (clinicaltrials.gov) - Jul 12, 2012
P1, N=4, Terminated, Sponsor: Stanford University
Completed --> Terminated; low accrual N=35 --> 4
- || 5-fluorouracil / Generic mfg., irinotecan / Generic mfg.
New P3 trial: ITACA-S: Intergroup Trial of Adjuvant Chemotherapy in Adenocarcinoma of the Stomach (clinicaltrials.gov) - Jul 12, 2012
P3, N=1100, Completed, Sponsor: Mario Negri Institute for Pharmacological Research