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128 Companies |
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121 Products |
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121 Products |
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104 Mechanisms of Action |
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7 Trials |
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1812 News |
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- Trial primary completion date: Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy (clinicaltrials.gov) - Mar 7, 2015
P=N/A, N=111, Active, not recruiting, Sponsor: Memorial Sloan Kettering Cancer Center.
Trial primary completion date: Feb 2015 --> Feb 2016
- Folotyn (pralatrexate) / Aurobindo
Trial primary completion date, Combination therapy, Metastases: Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer (clinicaltrials.gov) - Mar 7, 2015
P2, N=33, Active, not recruiting, Sponsor: Roswell Park Cancer Institute
Trial primary completion date: Feb 2015 --> Feb 2016 Trial primary completion date: Nov 2014 --> Jun 2015
- TheraCIM (nimotuzumab) / Daiichi Sankyo, Oncoscience, Biocon
Enrollment change, Trial withdrawal, Surgery, Metastases: Neoadjuvant Chemotherapy of Nimotuzumab Plus Nab-Paclitaxel in Squamous Cell Carcinoma of Esophagus (clinicaltrials.gov) - Mar 7, 2015
P2, N=0, Withdrawn, Sponsor: Zhejiang University
Trial primary completion date: Nov 2014 --> Jun 2015 N=40 --> 0 | Not yet recruiting --> Withdrawn
- TheraCIM (nimotuzumab) / Daiichi Sankyo, Oncoscience, Biocon
Enrollment change, Trial withdrawal, Metastases: Nimotuzumab Plus Nab-paclitaxel and Cisplatin in Treating Patients With Advanced Esophageal Carcinoma (clinicaltrials.gov) - Mar 7, 2015
P2, N=0, Withdrawn, Sponsor: Zhejiang University
N=40 --> 0 | Not yet recruiting --> Withdrawn N=40 --> 0 | Not yet recruiting --> Withdrawn
- 5-fluorouracil / Generic mfg., albumin-bound paclitaxel / Generic mfg.
Enrollment change, Trial withdrawal, Surgery, Metastases: Neoadjuvant Chemotherapy of Nanoparticle Albumin-bound Paclitaxel in Squamous Cell Carcinoma of Esophagus (clinicaltrials.gov) - Mar 7, 2015
P2, N=0, Withdrawn, Sponsor: Zhejiang University
N=40 --> 0 | Not yet recruiting --> Withdrawn N=40 --> 0 | Not yet recruiting --> Withdrawn
- | erlotinib / Generic mfg.
Enrollment change, Metastases: Erlotinib and Radiation Therapy in Treating Older Patients With Stage I, Stage II, Stage III, or Stage IV Esophageal Cancer (clinicaltrials.gov) - Mar 7, 2015
P2, N=22, Completed, Sponsor: Roswell Park Cancer Institute
N=40 --> 0 | Not yet recruiting --> Withdrawn N=17 --> 22
- octreotide acetate solution for injection / Generic mfg.
Surgery: The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery (clinicaltrials.gov) - Mar 7, 2015
P=N/A, N=36, Enrolling by invitation, Sponsor: St. James's Hospital, Ireland
- Clinical: Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia (clinicaltrials.gov) - Mar 5, 2015
P=N/A, N=90, Recruiting, Sponsor: Pere Clave
- || New P3 trial: NUTRIENTII: Nutritional Route In Esophageal Resection Trial II (clinicaltrials.gov) - Mar 5, 2015
P3, N=266, Not yet recruiting, Sponsor: Catharina Ziekenhuis Eindhoven
- ||| MM 111 / Elevation Oncology
Enrollment closed, Metastases: A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach (clinicaltrials.gov) - Mar 5, 2015
P2, N=120, Active, not recruiting, Sponsor: Merrimack Pharmaceuticals
N=17 --> 22 Recruiting --> Active, not recruiting
- Phase classification: Effect Of Piperine In Patients With Oropharyngeal Dysphagia (clinicaltrials.gov) - Mar 3, 2015
P1/2, N=40, Completed, Sponsor: Hospital de Matar
Recruiting --> Active, not recruiting Phase classification: P=N/A --> P1/2
- Trial primary completion date: Cardiaplication: A Novel Antireflux Operation (clinicaltrials.gov) - Feb 27, 2015
P=N/A, N=20, Active, not recruiting, Sponsor: Emory University
Phase classification: P=N/A --> P1/2 Trial primary completion date: Jun 2014 --> Feb 2015
- Exparel (bupivacaine liposome injectable suspension) / Pacira
New P2/3 trial: Exparel as a Nerve Block for Severe Hand Pain (clinicaltrials.gov) - Feb 27, 2015
P2/3, N=27, Recruiting, Sponsor: Jose Soberon, MD
- Victoza (liraglutide) / Novo Nordisk, Lyxumia (lixisenatide) / Zealand Pharma, Sanofi
Enrollment open, Trial primary completion date: Effects of Victoza (clinicaltrials.gov) - Feb 27, 2015
P1, N=72, Recruiting, Sponsor: Profil Institut f
Trial primary completion date: Jun 2014 --> Feb 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2015 --> Dec 2015
- Gastrocrom (cromolyn) / Viatris
New P4 trial: Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis (clinicaltrials.gov) - Feb 26, 2015
P4, N=24, Recruiting, Sponsor: University of Tennessee
- ||| Enrollment change: Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer (clinicaltrials.gov) - Feb 23, 2015
P1/2, N=63, Recruiting, Sponsor: Emory University
Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2015 --> Dec 2015 N=52 --> 63
- Trial completion, IO biomarker: Epithelial Damage in GERD (clinicaltrials.gov) - Feb 20, 2015
P=N/A, N=34, Completed, Sponsor: Maastricht University Medical Center
N=52 --> 63 Recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Electrical Pharyngeal Stimulation for Dysphagia Therapy in Tracheostomized Stroke Patients (clinicaltrials.gov) - Feb 20, 2015
P=N/A, N=30, Completed, Sponsor: University Hospital Muenster
Recruiting --> Completed Recruiting --> Completed | N=40 --> 30 | Trial primary completion date: Jun 2015 --> Aug 2014
- |||| rocuronium / Generic mfg.
Enrollment open: DEPTH: Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy (clinicaltrials.gov) - Feb 19, 2015
P4, N=66, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Recruiting --> Completed | N=40 --> 30 | Trial primary completion date: Jun 2015 --> Aug 2014 Not yet recruiting --> Recruiting
- prednisone / Generic mfg.
Enrollment open: Reduction in Symptomatic Esophageal Stricture Formation (clinicaltrials.gov) - Feb 13, 2015
P4, N=126, Recruiting, Sponsor: Florida Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- |||| Avastin (bevacizumab) / Roche
Trial completion, Metastases: XAGastric: Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma (clinicaltrials.gov) - Feb 13, 2015
P2, N=60, Completed, Sponsor: Duke University
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- TheraCIM (nimotuzumab) / Daiichi Sankyo, Oncoscience, Biocon
Enrollment change, Trial withdrawal, Trial primary completion date, Metastases: Phase II Study of Maintenance Treatment of Nimotuzumab for Advanced Esophageal Carcinoma (clinicaltrials.gov) - Feb 12, 2015
P2, N=0, Withdrawn, Sponsor: Zhejiang University
Active, not recruiting --> Completed N=20 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Dec 2015 --> Jan 2015
- Clinical: Transparent Cap-assisted Endoscopic Sclerotherapy (clinicaltrials.gov) - Feb 12, 2015
P=N/A, N=120, Not yet recruiting, Sponsor: Shanghai Zhongshan Hospital
- Avastin (bevacizumab) / Roche
Trial completion, Enrollment change, Trial primary completion date, Metastases: Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma (clinicaltrials.gov) - Feb 12, 2015
P2, N=22, Completed, Sponsor: Memorial Sloan Kettering Cancer Center.
N=20 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Dec 2015 --> Jan 2015 Active, not recruiting --> Completed | N=60 --> 22 | Trial primary completion date: Aug 2015 --> Feb 2015
- ||| lansoprazole / Generic mfg.
Trial completion: Reflux Disease Therapy in the Management of Childhood Asthma-data Entry and Analysis Only (clinicaltrials.gov) - Feb 11, 2015
P=N/A, N=59, Completed, Sponsor: Children's Center for Digestive Health Care
Active, not recruiting --> Completed | N=60 --> 22 | Trial primary completion date: Aug 2015 --> Feb 2015 Active, not recruiting --> Completed
- || Phase classification, Trial primary completion date: Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD) (clinicaltrials.gov) - Feb 10, 2015
P4, N=60, Recruiting, Sponsor: EndoGastric Solutions
Active, not recruiting --> Completed Phase classification: P3 --> P4 | Trial primary completion date: May 2014 --> May 2015
- esomeprazole / Generic mfg.
Clinical: The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study (clinicaltrials.gov) - Feb 10, 2015
P=N/A, N=20, Recruiting, Sponsor: Medical University of Graz
- lisinopril / Generic mfg.
New P4 trial: Drug to Prevent Pneumonia in the Tube Fed (clinicaltrials.gov) - Feb 9, 2015
P4, N=93, Terminated, Sponsor: Chinese University of Hong Kong
- Metastases: mEGA: Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and Stomach (clinicaltrials.gov) - Feb 9, 2015
P=N/A, N=20, Recruiting, Sponsor: Georgetown University
- Trial primary completion date, Surgery: Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=20, Enrolling by invitation, Sponsor: Arlyne Thung
Phase classification: P3 --> P4 | Trial primary completion date: May 2014 --> May 2015 Trial primary completion date: Nov 2014 --> Dec 2016
- ||| Trial completion, Enrollment change: HALO Patient Registry: Ablation of Barrett's Esophagus (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=5521, Completed, Sponsor: Covidien, GI Solutions
Trial primary completion date: Nov 2014 --> Dec 2016 Active, not recruiting --> Completed | N=10000 --> 5521
- ||| esomeprazole / Generic mfg.
Trial completion: Ablation of Intestinal Metaplasia Containing Dysplasia (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=127, Completed, Sponsor: Covidien, GI Solutions
Active, not recruiting --> Completed | N=10000 --> 5521 Active, not recruiting --> Completed
- Trial completion: Effect of CCRT on Respiratory Performance and Functional Capacity in Esophagus Cancer Patients (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=100, Completed, Sponsor: Far Eastern Memorial Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. (clinicaltrials.gov) - Feb 5, 2015
P3, N=28, Completed, Sponsor: Hospital Clinic of Barcelona
Recruiting --> Completed Recruiting --> Completed | N=46 --> 28 | Trial primary completion date: Dec 2013 --> Jun 2014
- esomeprazole / Generic mfg.
Trial primary completion date: BRAVO Study for Functional Dyspepsia (clinicaltrials.gov) - Feb 3, 2015
P4, N=130, Recruiting, Sponsor: Chinese University of Hong Kong
Recruiting --> Completed | N=46 --> 28 | Trial primary completion date: Dec 2013 --> Jun 2014 Trial primary completion date: Dec 2014 --> Dec 2015
- Carafate (sucralfate) / AbbVie
Clinical: EoE: The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis (clinicaltrials.gov) - Feb 2, 2015
P0, N=6, Recruiting, Sponsor: Mayo Clinic
- ||||| Dexilant (dexlansoprazole) / Takeda
New P4 trial: Dexlansoprazole in Asian Participants With Gastroesophageal Reflux Disease (clinicaltrials.gov) - Jan 30, 2015
P4, N=300, Not yet recruiting, Sponsor: Takeda
- Enrollment change, Trial termination, Trial primary completion date: A Dose-Optimization Study for the Initial Treatment of Dysplastic Barrett's Esophagus With trūFreeze™ Spray Cryotherapy (clinicaltrials.gov) - Jan 29, 2015
P=N/A, N=36, Terminated, Sponsor: University of North Carolina, Chapel Hill
Trial primary completion date: Dec 2014 --> Dec 2015 N=90 --> 36 | Recruiting --> Terminated | Trial primary completion date: Apr 2015 --> Nov 2014; poor enrollment and study design
- esomeprazole / Generic mfg.
Trial primary completion date: Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy (clinicaltrials.gov) - Jan 29, 2015
P4, N=500, Recruiting, Sponsor: Chang Gung Memorial Hospital
N=90 --> 36 | Recruiting --> Terminated | Trial primary completion date: Apr 2015 --> Nov 2014; poor enrollment and study design Trial primary completion date: Dec 2014 --> Jun 2015
- Trial completion, Enrollment change: Topical Bethanechol for Improvement of Esophageal Dysmotility (clinicaltrials.gov) - Jan 29, 2015
P1, N=5, Completed, Sponsor: Georgia Regents University
Trial primary completion date: Dec 2014 --> Jun 2015 Recruiting --> Completed | N=10 --> 5
- ||| Avastin (bevacizumab) / Roche
Enrollment change, Metastases: XAGastric: Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma (clinicaltrials.gov) - Jan 28, 2015
P2, N=60, Active, not recruiting, Sponsor: Duke University
Recruiting --> Completed | N=10 --> 5 N=37 --> 60
- Trial primary completion date: Proton Beam Therapy to Treat Esophageal Cancer (clinicaltrials.gov) - Jan 26, 2015
P1, N=40, Recruiting, Sponsor: Washington University School of Medicine
N=37 --> 60 Trial primary completion date: Jan 2015 --> Jan 2021
- ||||| AMG 337 / ImmunityBio, Amgen
New P1/2 trial, Metastases: C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer (clinicaltrials.gov) - Jan 26, 2015
P1/2, N=308, Not yet recruiting, Sponsor: Eastern Cooperative Oncology Group
- ||| Trial completion: Pronase Improves Efficacy of Chromoendoscopy Screening on Esophageal Cancer (clinicaltrials.gov) - Jan 26, 2015
P=N/A, N=1000, Completed, Sponsor: Xijing Hospital of Digestive Diseases
Trial primary completion date: Jan 2015 --> Jan 2021 Recruiting --> Completed
- Trial completion, Enrollment change: Comparison of O-type Hybrid Knife and IT Knife in ESD (clinicaltrials.gov) - Jan 26, 2015
P=N/A, N=78, Completed, Sponsor: Xijing Hospital of Digestive Diseases
Recruiting --> Completed Recruiting --> Completed | N=40 --> 78
- Trial completion, Trial primary completion date: The Objective is to Respond to Patients' Needs in the Field of Larynx Replacement (clinicaltrials.gov) - Jan 26, 2015
P1, N=10, Completed, Sponsor: University Hospital, Strasbourg, France
Recruiting --> Completed | N=40 --> 78 Recruiting --> Completed | Trial primary completion date: Feb 2013 --> Aug 2013
- Trial completion: Effect of Sub-mental Sensitive Transcutaneous Electrical Stimulation on Pharyngeal Muscles Control : TENSVIRT Study (clinicaltrials.gov) - Jan 22, 2015
P=N/A, N=10, Completed, Sponsor: University Hospital, Rouen
Recruiting --> Completed | Trial primary completion date: Feb 2013 --> Aug 2013 Recruiting --> Completed
- Enrollment open: Defining the Radiotherapy Dose and Volume Parameters Affecting Postoperative Complications in Esophageal Cancer Patients (clinicaltrials.gov) - Jan 22, 2015
P=N/A, N=150, Enrolling by invitation, Sponsor: Maastricht Radiation Oncology
Recruiting --> Completed Not yet recruiting --> Enrolling by invitation
- |||| dexlansoprazole / Generic mfg.
Trial completion, Trial primary completion date: Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents (clinicaltrials.gov) - Jan 22, 2015
P2, N=63, Completed, Sponsor: Takeda
Not yet recruiting --> Enrolling by invitation Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Nov 2014
- Trial primary completion date: Botulinum Toxin Injection in Hypercontractile Esophagus (clinicaltrials.gov) - Jan 18, 2015
P2, N=28, Recruiting, Sponsor: Hospices Civils de Lyon
Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Nov 2014 Trial primary completion date: May 2015 --> May 2016