Endometrial Stromal Tumors MOAs - LARVOL Sigma

Endometrial Stromal Tumors

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36 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	2										4										6										8										10										12										14										16										18										20



AXL inhib




Microtubule inhib




VEGFR-1 inhib




AKT inhib




Estrogen receptor mod




FGFR1 inhib




PDGFR inhib




c-KIT inhib




Microtubule inhib




T-cell stim




mTOR inhib




DNA cross linking agent




Estrogen receptor mod




PI3K inhib




TIE-2 inhib




AKT inhib




CDK6 inhib




EGFR mutation inhib




Gonadotropin inhib




HIF-1 inhib




HIF-1 inhib




Angiopoietin 2 inhib




Aurora kinase A inhib




Bcl2 inhib




Bcl2 inhib




CDK6 inhib




CTLA4 inhib




Endothelin A receptor antag




Folate receptor 1 inhib




Fyn inhib




GM-CSF agon




GM-CSF agon




Histamine release inhib




STAT3 inhib




Steryl sulfatase inhib




Trk receptor antag