Down Syndrome
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 9 Companies   10 Products   10 Products   12 Mechanisms of Action   0 Trials   185 News 


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  • ||||||||||  Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite (clinicaltrials.gov) -  Feb 16, 2019   
    P=N/A,  N=23, Completed, 
    Recruiting --> Completed | Trial completion date: Oct 2017 --> Dec 2016 | Trial primary completion date: Mar 2017 --> Dec 2016 Recruiting --> Completed | N=300 --> 23 | Trial completion date: Jun 2020 --> Aug 2018 | Trial primary completion date: Jun 2015 --> Aug 2018
  • ||||||||||  Trial completion:  Natural History of Amyloid Deposition in Adults With Down Syndrome (clinicaltrials.gov) -  Aug 10, 2018   
    P=N/A,  N=81, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Oct 2018 --> Oct 2017 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Enrollment change, Trial completion date:  Treatment of Sleep Disturbances in School-age Children With Down Syndrome (clinicaltrials.gov) -  Jun 4, 2018   
    P=N/A,  N=34, Completed, 
    Recruiting --> Completed | Trial primary completion date: Dec 2017 --> Aug 2017 Recruiting --> Completed | N=80 --> 34 | Trial completion date: Aug 2018 --> May 2018
  • ||||||||||  Trial primary completion date:  Treatment of Sleep Disturbances in School-age Children With Down Syndrome (clinicaltrials.gov) -  Oct 5, 2017   
    P=N/A,  N=80, Recruiting, 
    Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Jun 2017 | Trial completion date: Dec 2017 --> Jun 2017 Trial primary completion date: Jun 2017 --> Jun 2018
  • ||||||||||  Trial completion, Preclinical:  DEPOSA: T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients (clinicaltrials.gov) -  Aug 15, 2017   
    P=N/A,  N=933, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Apr 2017 --> Sep 2016 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Trial initiation date, Trial primary completion date:  Frequency of Metabolic Syndrome in Down Syndrome Patients (clinicaltrials.gov) -  May 5, 2017   
    P=N/A,  N=96, Completed, 
    Trial primary completion date: Apr 2017 --> Apr 2018 Not yet recruiting --> Completed | Initiation date: May 2009 --> Sep 2009 | Trial primary completion date: May 2009 --> Dec 2009
  • ||||||||||  Biomarker, Trial completion, Trial primary completion date:  Down Syndrome Biomarker Initiative (DSBI) (clinicaltrials.gov) -  May 2, 2017   
    P=N/A,  N=12, Completed, 
    Not yet recruiting --> Completed | Initiation date: May 2009 --> Sep 2009 | Trial primary completion date: May 2009 --> Dec 2009 Active, not recruiting --> Completed | Trial primary completion date: Jan 2017 --> Apr 2017
  • ||||||||||  Trial completion:  Performance Analysis in Down Syndrome on Mobile Phone (clinicaltrials.gov) -  Apr 11, 2017   
    P=N/A,  N=100, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Jan 2017 --> Apr 2017 Not yet recruiting --> Completed
  • ||||||||||  basmisanil (RG1662) / Roche
    Trial termination:  A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age (clinicaltrials.gov) -  Mar 27, 2017   
    P2,  N=45, Terminated, 
    Active, not recruiting --> Terminated; Study was terminated due to data from another study showing no efficacy. There were no safety issues of concern.
  • ||||||||||  Trial completion, Trial primary completion date:  Intensive Dysarthria Sessions in Adults and Children With Down Syndrome (clinicaltrials.gov) -  Nov 23, 2016   
    P=N/A,  N=5, Completed, 
    Trial primary completion date: Dec 2018 --> Dec 2017 Active, not recruiting --> Completed | Trial primary completion date: Nov 2016 --> May 2016
  • ||||||||||  Enrollment closed, Enrollment change:  Natural History of Amyloid Deposition in Adults With Down Syndrome (clinicaltrials.gov) -  Nov 2, 2016   
    P=N/A,  N=81, Active, not recruiting, 
    Active, not recruiting --> Completed | Trial primary completion date: Nov 2016 --> May 2016 Recruiting --> Active, not recruiting | N=64 --> 81
  • ||||||||||  Enrollment closed, Preclinical, Trial primary completion date:  DEPOSA: T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients (clinicaltrials.gov) -  Sep 29, 2016   
    P=N/A,  N=933, Active, not recruiting, 
    Recruiting --> Active, not recruiting | N=64 --> 81 Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Sep 2016
  • ||||||||||  basmisanil (RG1662) / Roche
    Trial primary completion date:  A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age (clinicaltrials.gov) -  Aug 8, 2016   
    P2,  N=45, Active, not recruiting, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Sep 2016 Trial primary completion date: Jan 2017 --> Aug 2016
  • ||||||||||  Biomarker, Trial primary completion date:  Down Syndrome Biomarker Initiative (DSBI) (clinicaltrials.gov) -  Jul 19, 2016   
    P=N/A,  N=12, Active, not recruiting, 
    Active, not recruiting --> Completed Trial primary completion date: Jun 2016 --> Dec 2016
  • ||||||||||  basmisanil (RG1662) / Roche
    Enrollment closed, Trial primary completion date:  A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age (clinicaltrials.gov) -  Jul 5, 2016   
    P2,  N=44, Active, not recruiting, 
    Recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2017 --> Jan 2017
  • ||||||||||  Enrollment closed, Enrollment change, Trial primary completion date:  Intensive Dysarthria Sessions in Adults and Children With Down Syndrome (clinicaltrials.gov) -  Feb 3, 2016   
    P=N/A,  N=3, Active, not recruiting, 
    Active, not recruiting --> Recruiting Recruiting --> Active, not recruiting | N=12 --> 3 | Trial primary completion date: Nov 2015 --> Nov 2016
  • ||||||||||  Trial primary completion date:  Natural History of Amyloid Deposition in Adults With Down Syndrome (clinicaltrials.gov) -  Jan 18, 2016   
    P=N/A,  N=64, Recruiting, 
    Trial primary completion date: Dec 2015 --> Mar 2016 Trial primary completion date: Jun 2011 --> Jun 2017