Dentin Sensitivity News - LARVOL Sigma

Dentin Sensitivity

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1 Mechanism of Action

|||||||||| Trial completion: A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli. (clinicaltrials.gov) - May 16, 2016
P=N/A, N=221, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Completed

|||||||||| New trial: Dentine Tubule Occlusion Assessment in a Modified in Situ Model (clinicaltrials.gov) - May 11, 2016
P=N/A, N=24, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| New P4 trial: Effect of a Self-adhering Material in Dental Hypersensitivity (clinicaltrials.gov) - May 9, 2016
P4, N=17, Completed, Sponsor: Università degli Studi di Sassari

|||||||||| Enrollment open: Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - May 8, 2016
P4, N=214, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| New trial, HEOR: Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health (clinicaltrials.gov) - Apr 27, 2016
P=N/A, N=75, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| New trial: A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice. (clinicaltrials.gov) - Apr 27, 2016
P=N/A, N=240, Completed, Sponsor: GlaxoSmithKline

|||||||||| New trial: The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH) (clinicaltrials.gov) - Apr 26, 2016
P=N/A, N=230, Recruiting, Sponsor: GlaxoSmithKline

|||||||||| Enrollment open: Study Investigating Efficacy of an Occluding Dentifrice for Dentine Hypersensitivity (clinicaltrials.gov) - Apr 25, 2016
P=N/A, N=140, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting

|||||||||| Enrollment open, Trial primary completion date: The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Apr 25, 2016
P=N/A, N=230, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Trial primary completion date: Jan 2016 --> Jun 2016

|||||||||| New P4 trial: Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Apr 8, 2016
P4, N=214, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| New trial: Study Investigating Efficacy of an Occluding Dentifrice for Dentine Hypersensitivity (clinicaltrials.gov) - Mar 10, 2016
P=N/A, N=140, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| Enrollment closed: SSDH: An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity (clinicaltrials.gov) - Mar 7, 2016
P4, N=60, Active, not recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting --> Recruiting | Trial primary completion date: Jan 2016 --> Jun 2016 Recruiting --> Active, not recruiting

|||||||||| New trial: A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli. (clinicaltrials.gov) - Jan 11, 2016
P=N/A, N=240, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| New trial: The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Nov 24, 2015
P=N/A, N=230, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| New trial: Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Sep 8, 2015
P=N/A, N=240, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| Enrollment open, Trial primary completion date: SSDH: An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity (clinicaltrials.gov) - Jul 30, 2015
P4, N=60, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting | Trial primary completion date: Dec 2015 --> May 2016

|||||||||| Trial completion: Tooth Sensitivity Relief by Two Mouthrinses (clinicaltrials.gov) - Jul 9, 2015
P=N/A, N=174, Completed, Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
Not yet recruiting --> Recruiting | Trial primary completion date: Dec 2015 --> May 2016 Withheld --> Completed

|||||||||| New P4 trial: Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity (clinicaltrials.gov) - Jun 26, 2015
P4, N=60, Completed, Sponsor: University of Sao Paulo

|||||||||| New P4 trial: SSDH: An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity (clinicaltrials.gov) - Jun 20, 2015
P4, N=60, Not yet recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute

|||||||||| Trial completion: A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=153, Completed, Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
Withheld --> Completed Withheld --> Completed

|||||||||| Trial completion: A Study of the Relief of Tooth Sensitivity of an Experimental Mouthrinse Device (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=226, Completed, Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
Withheld --> Completed Withheld --> Completed

||||||||||  naproxen / Generic mfg.
New trial:  Naproxen on Tooth Sensitivity Caused by In-office Bleaching (clinicaltrials.gov) -  Jun 4, 2015
P=N/A, N=50, Active, not recruiting,  Sponsor: Universidade Federal de Sergipe

|||||||||| New P4 trial: Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment (clinicaltrials.gov) - Jun 3, 2015
P4, N=60, Completed, Sponsor: University of Campinas, Brazil

|||||||||| New trial: Dentin Hypersensitivity Following Non-surgical Periodontal Therapy With Hand or Ultrasonic Instruments (clinicaltrials.gov) - May 6, 2015
P=N/A, N=500, Completed, Sponsor: hadeer ehab

|||||||||| Clinical: Clinical Study to Evaluate the Efficacy of Two Dentifrices for Dentine Hypersensitivity (clinicaltrials.gov) - Feb 26, 2015
P=N/A, N=304, Completed, Sponsor: GlaxoSmithKline

|||||||||| Trial completion: Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Feb 5, 2015
P2, N=198, Completed, Sponsor: GlaxoSmithKline
Withheld --> Completed Recruiting --> Completed

|||||||||| Phase classification: Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity (clinicaltrials.gov) - Jan 26, 2015
P2, N=32, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed Phase classification: P3 --> P2

|||||||||| New P4 trial, Preclinical: The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching (clinicaltrials.gov) - Dec 13, 2014
P4, N=113, Completed, Sponsor: University of Sao Paulo

|||||||||| Enrollment open: Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Oct 15, 2014
P2, N=200, Recruiting, Sponsor: GlaxoSmithKline
Phase classification: P3 --> P2 Not yet recruiting --> Recruiting

|||||||||| Trial completion: Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity (clinicaltrials.gov) - Sep 5, 2014
P=N/A, N=375, Completed, Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| New P2 trial: Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Aug 27, 2014
P2, N=200, Not yet recruiting, Sponsor: GlaxoSmithKline

|||||||||| Trial completion: Evaluation of the Safety and Efficacy of an Oxalate Gel or Negative Control on Dentinal Hypersensitivity (clinicaltrials.gov) - Jul 16, 2014
P=N/A, N=70, Completed, Sponsor: Procter and Gamble
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Clinical: Evaluation of the Safety and Efficacy of an Oxalate Gel or Negative Control on Dentinal Hypersensitivity (clinicaltrials.gov) - Jul 14, 2014
P=N/A, N=70, Active, not recruiting, Sponsor: Procter and Gamble

|||||||||| New P2/3 trial: Effectiveness of a Homecare Dentin Hypersensitivity Gel (clinicaltrials.gov) - Apr 24, 2014
P2/3, N=126, Completed, Sponsor: Universidade Federal de Santa Maria

|||||||||| Enrollment change: BLESMOK: Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients (clinicaltrials.gov) - Feb 19, 2014
P4, N=120, Completed, Sponsor: University of Chile
Active, not recruiting --> Completed N=60 --> 120

|||||||||| Trial completion: BLESMOK: Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients (clinicaltrials.gov) - Jan 30, 2014
P4, N=120, Completed, Sponsor: University of Chile
N=60 --> 120 Not yet recruiting --> Completed

|||||||||| New P4 trial: BLESMOK: Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients (clinicaltrials.gov) - Dec 19, 2013
P4, N=120, Completed, Sponsor: University of Chile

|||||||||| Trial completion: In-office Bleaching With a 2-day Interval Between Sessions: Tooth Sensitivity (clinicaltrials.gov) - Oct 8, 2013
P=N/A, N=40, Completed, Sponsor: Universidade Estadual de Ponta Grossa
Not yet recruiting --> Completed Not yet recruiting --> Completed

|||||||||| Trial completion: Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - May 15, 2013
P3, N=119, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Completed Recruiting --> Completed

|||||||||| New P3 trial: Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Apr 7, 2013
P3, N=119, Completed, Sponsor: GlaxoSmithKline

|||||||||| Trial completion: Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity (clinicaltrials.gov) - Jan 9, 2013
P2, N=140, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| New P3 trial: The Efficacy of a Dentifrice in Providing Relief From Dentinal Hypersensitivity (clinicaltrials.gov) - Nov 7, 2012
P3, N=120, Completed, Sponsor: GlaxoSmithKline

|||||||||| Trial completion: Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity (clinicaltrials.gov) - Oct 31, 2012
P3, N=113, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm® (clinicaltrials.gov) - Oct 30, 2012
P=N/A, N=80, Completed, Sponsor: Zimmer, Inc.
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| New P2 trial: Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity (clinicaltrials.gov) - Sep 20, 2012
P2, N=140, Completed, Sponsor: GlaxoSmithKline

|||||||||| Trial completion: The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity (clinicaltrials.gov) - Aug 1, 2012
P3, N=120, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| New P3 trial: The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity (clinicaltrials.gov) - May 3, 2012
P3, N=120, Completed, Sponsor: GlaxoSmithKline

|||||||||| New P3 trial: Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity (clinicaltrials.gov) - May 3, 2012
P3, N=113, Completed, Sponsor: GlaxoSmithKline

||||||||||  etoricoxib / Generic mfg.
Enrollment change:  Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching (clinicaltrials.gov) -  Oct 2, 2011
P=N/A, N=30, Enrolling by invitation,  Sponsor: Eloisa Andrade de Paula
Active, not recruiting --> Completed N=75 --> 30

||||||||||  etoricoxib / Generic mfg.
Enrollment open:  Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching (clinicaltrials.gov) -  Oct 2, 2011
P=N/A, N=30, Enrolling by invitation,  Sponsor: Eloisa Andrade de Paula
N=75 --> 30 Not yet recruiting --> Enrolling by invitation