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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- | venlafaxine / Generic mfg.
Trial completion, Enrollment change: Venlafaxine for Depression in Alzheimer's Disease (DIADs-3) (clinicaltrials.gov) - Mar 7, 2017
P=N/A, N=5, Completed, Sponsor: Johns Hopkins University
Recruiting --> Completed | N=50 --> 5
- | carvedilol / Generic mfg.
Trial completion, Enrollment change: Trial of Carvedilol in Alzheimer's Disease (clinicaltrials.gov) - Mar 7, 2017
P4, N=30, Completed, Sponsor: Johns Hopkins University
Recruiting --> Completed | N=50 --> 5 Recruiting --> Completed | N=50 --> 30
- ||||||| Nivadil (nilvadipine) / Cortice Biosci
Trial completion, P3 data, Trial initiation date, Trial primary completion date: A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease (clinicaltrials.gov) - Mar 6, 2017
P3, N=511, Completed, Sponsor: Prof Brian Lawlor
Recruiting --> Completed | N=50 --> 30 Active, not recruiting --> Completed | Initiation date: Oct 2012 --> Apr 2013 | Trial primary completion date: Sep 2016 --> Dec 2016
- | Phase classification: Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis (clinicaltrials.gov) - Mar 6, 2017
P=N/A, N=158, Recruiting, Sponsor: University of Miami
Active, not recruiting --> Completed | Initiation date: Oct 2012 --> Apr 2013 | Trial primary completion date: Sep 2016 --> Dec 2016 Phase classification: P2 --> P=N/A
- | Trial primary completion date: PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers (clinicaltrials.gov) - Mar 6, 2017
P1, N=21, Active, not recruiting, Sponsor: Dean F. Wong, MD, PhD
Phase classification: P2 --> P=N/A Trial primary completion date: Dec 2016 --> Dec 2017
- | Enrollment closed, Enrollment change, Trial primary completion date: PAICOD: Peri-Anesthetic Imaging of Cognitive Dysfunction (clinicaltrials.gov) - Mar 3, 2017
P=N/A, N=6, Active, not recruiting, Sponsor: Vanderbilt University
Trial primary completion date: Dec 2016 --> Dec 2017 Recruiting --> Active, not recruiting | N=15 --> 6 | Trial primary completion date: Dec 2014 --> Dec 2018
- | Trial primary completion date: Effectiveness of a Multifactorial Intervention on Frailty (clinicaltrials.gov) - Mar 3, 2017
P=N/A, N=352, Active, not recruiting, Sponsor: Jordi Gol i Gurina Foundation
Recruiting --> Active, not recruiting | N=15 --> 6 | Trial primary completion date: Dec 2014 --> Dec 2018 Trial primary completion date: Dec 2014 --> Dec 2016
- Trial termination, Trial primary completion date: An Exploratory Study to Compare the Differences in Nutritional Status Between Patients With Mild and Moderate Alzheimer's Disease (AD) and Cognitively Intact Healthy People in an Asian Population (clinicaltrials.gov) - Mar 3, 2017
P=N/A, N=191, Terminated, Sponsor: PTSH Holding Singapore Pte Ltd
Trial primary completion date: Dec 2014 --> Dec 2016 Recruiting --> Terminated | Trial primary completion date: Nov 2015 --> Nov 2016; Stop the study for futility based on recommendation from Independent Data Committee.
- | Trial primary completion date: DELINEATE: Delirium in the Emergency Department and Its Extension Into Hospitalization (clinicaltrials.gov) - Feb 28, 2017
P=N/A, N=228, Completed, Sponsor: Vanderbilt University
Recruiting --> Terminated | Trial primary completion date: Nov 2015 --> Nov 2016; Stop the study for futility based on recommendation from Independent Data Committee. Trial primary completion date: Jul 2015 --> Nov 2014
- || Trial primary completion date: COGHIC-AV45: Amyloid Imaging and Cognitive Impairment After Intracerebral Hemorrhage (clinicaltrials.gov) - Feb 23, 2017
P=N/A, N=70, Recruiting, Sponsor: University Hospital, Toulouse
Trial primary completion date: Jul 2015 --> Nov 2014 Trial primary completion date: Dec 2015 --> Jun 2017
- | Trial completion: PRO-MH2: Utilization of 31P-Nuclear Magnetic Resonance Spectroscopy to Monitor Brain Energy Deficit in Huntington Disease (clinicaltrials.gov) - Feb 23, 2017
P=N/A, N=50, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Trial primary completion date: Dec 2015 --> Jun 2017 Recruiting --> Completed
- Phase classification, Trial primary completion date: Brain-Computer Interface System for Training Memory and Attention in Elderly (clinicaltrials.gov) - Feb 13, 2017
P2, N=240, Recruiting, Sponsor: Duke-NUS Graduate Medical School
Recruiting --> Completed Phase classification: P2/3 --> P2 | Trial primary completion date: Jul 2016 --> Jul 2017
- | Trial completion: Memory Aid for Informed Consent in Alzheimer's Research (clinicaltrials.gov) - Feb 6, 2017
P=N/A, N=110, Completed, Sponsor: National Institute on Aging (NIA)
Phase classification: P2/3 --> P2 | Trial primary completion date: Jul 2016 --> Jul 2017 No longer recruiting --> Completed
- ||||||| Trial completion: Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's (clinicaltrials.gov) - Feb 6, 2017
P3, N=1600, Completed, Sponsor: Myrexis Inc.
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Dutch EASYcare Study (clinicaltrials.gov) - Feb 6, 2017
P=N/A, N=155, Completed, Sponsor: Radboud University
Active, not recruiting --> Completed No longer recruiting --> Completed
- Trial primary completion date: Tau Imaging of Chronic Traumatic Encephalopathy (clinicaltrials.gov) - Feb 3, 2017
P2, N=30, Enrolling by invitation, Sponsor: Marcelo F. Di Carli, MD, FACC
No longer recruiting --> Completed Trial primary completion date: Dec 2016 --> Dec 2017
- Trial completion, Phase classification: Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness Disorders (clinicaltrials.gov) - Feb 3, 2017
P=N/A, N=10, Completed, Sponsor: University Hospital of Ferrara
Trial primary completion date: Dec 2016 --> Dec 2017 Recruiting --> Completed | Phase classification: P1 --> PN/A
- || PF-02545920 / Pfizer
Trial primary completion date: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 (clinicaltrials.gov) - Feb 2, 2017
P2, N=230, Recruiting, Sponsor: Pfizer
Recruiting --> Completed | Phase classification: P1 --> PN/A Trial primary completion date: Sep 2017 --> Feb 2017
- Trial completion, Trial primary completion date: ISALP: Isotopic Imaging for Prodromal Alzheimer's Disease (clinicaltrials.gov) - Feb 1, 2017
P=N/A, N=143, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
Trial primary completion date: Sep 2017 --> Feb 2017 Active, not recruiting --> Completed | Trial primary completion date: Mar 2016 --> Sep 2016
- Trial completion: TMS-AD: Enhancing Neuroplasticity and Frontal Lobe Function in Patients With Mild Alzheimer's Disease (clinicaltrials.gov) - Feb 1, 2017
P2, N=49, Completed, Sponsor: Centre for Addiction and Mental Health
Active, not recruiting --> Completed | Trial primary completion date: Mar 2016 --> Sep 2016 Recruiting --> Completed
- Trial completion, Enrollment change: GRECogVASC: Post-stroke Cognitive Impairment and Dementia (clinicaltrials.gov) - Jan 31, 2017
P=N/A, N=1635, Completed, Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting --> Completed Recruiting --> Completed | N=1208 --> 1635
- Phase classification, Enrollment change, Trial primary completion date: Energy Metabolism and Cognitive Aging (clinicaltrials.gov) - Jan 30, 2017
P=N/A, N=60, Recruiting, Sponsor: University of Cincinnati
Recruiting --> Completed | N=1208 --> 1635 Phase classification: P4 --> P=N/A | N=40 --> 60 | Trial primary completion date: Dec 2016 --> Dec 2018
- Trial completion: Safety Study of Nicotinamide to Treat Alzheimer's Disease (clinicaltrials.gov) - Jan 26, 2017
P1/2, N=50, Completed, Sponsor: University of California, Irvine
Phase classification: P4 --> P=N/A | N=40 --> 60 | Trial primary completion date: Dec 2016 --> Dec 2018 Active, not recruiting --> Completed
- Trial termination, Trial primary completion date: Study of Retinal Findings in People With Signs and Symptoms of Alzheimer s Disease Enrolled in 09-M-0198 (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=33, Terminated, Sponsor: National Eye Institute (NEI)
Active, not recruiting --> Completed Active, not recruiting --> Terminated | Trial primary completion date: Oct 2017 --> Jan 2017
- Trial completion: mRNAOrtho: Postoperative Delirium in Hip Arthroplasty Patients (clinicaltrials.gov) - Jan 23, 2017
P=N/A, N=49, Completed, Sponsor: Ohio State University
Active, not recruiting --> Terminated | Trial primary completion date: Oct 2017 --> Jan 2017 Recruiting --> Completed
- atorvastatin / Generic mfg.
Trial primary completion date: Modulation of Monocyte Activation by Atorvastatin in HIV Infection (clinicaltrials.gov) - Jan 17, 2017
P4, N=15, Active, not recruiting, Sponsor: University of Pennsylvania
Recruiting --> Completed Trial primary completion date: Oct 2016 --> Oct 2017
- ||||||| idalopirdine (Lu AE58054) / Otsuka, Eli Lilly, Denovo
Trial completion: STARBRIGHT: Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With an Acetylcholinesterase Inhibitor (clinicaltrials.gov) - Jan 17, 2017
P3, N=734, Completed, Sponsor: H. Lundbeck A/S
Trial primary completion date: Oct 2016 --> Oct 2017 Active, not recruiting --> Completed
- ||||| idalopirdine (Lu AE58054) / Otsuka, Eli Lilly, Denovo
Enrollment closed: STAR Extension: Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease (clinicaltrials.gov) - Jan 13, 2017
P3, N=1463, Active, not recruiting, Sponsor: H. Lundbeck A/S
Active, not recruiting --> Completed Enrolling by invitation --> Active, not recruiting
- Trial primary completion date: Home-delivered Intervention for Depressed, Cognitively Impaired Elders (clinicaltrials.gov) - Jan 11, 2017
P=N/A, N=176, Recruiting, Sponsor: Weill Medical College of Cornell University
Enrolling by invitation --> Active, not recruiting Trial primary completion date: Jul 2016 --> Feb 2017
- Enrollment change, Surgery: POPE: Postoperative Neuroinflammation and Cognitive Dysfunction After Abdominal Surgery (clinicaltrials.gov) - Jan 11, 2017
P4, N=8, Completed, Sponsor: Karolinska University Hospital
Trial primary completion date: Jul 2016 --> Feb 2017 N=20 --> 8
- Enrollment closed, Trial primary completion date, Surgery: DeprPOCD: Study of Depressive Symptoms Predicting Postoperative Cognitive Dysfunction (clinicaltrials.gov) - Jan 11, 2017
P=N/A, N=300, Active, not recruiting, Sponsor: Universit
N=20 --> 8 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Aug 2017
- Trial completion, Trial primary completion date: Insulin Resistance and Cognitive Dysfunction in Obese Adolescents: Pilot Study (clinicaltrials.gov) - Jan 10, 2017
P=N/A, N=56, Completed, Sponsor: Winthrop University Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Aug 2017 Recruiting --> Completed | Trial primary completion date: May 2016 --> Feb 2016
- || Rexulti (brexpiprazole) / Lundbeck, Otsuka
Trial primary completion date: Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo (clinicaltrials.gov) - Jan 10, 2017
P=N/A, N=450, Enrolling by invitation, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting --> Completed | Trial primary completion date: May 2016 --> Feb 2016 Trial primary completion date: Sep 2017 --> Jun 2017
- rivastigmine transdermal / Generic mfg.
Trial primary completion date: RIVET: Rivastigmine Patch in Veterans With Cognitive Impairment Following TBI (clinicaltrials.gov) - Jan 6, 2017
P3, N=96, Active, not recruiting, Sponsor: VA Office of Research and Development
Trial primary completion date: Sep 2017 --> Jun 2017 Trial primary completion date: Feb 2016 --> May 2016
- donepezil / Generic mfg.
Trial primary completion date: Donepezil and the Risk of Falls in Seniors With Cognitive Impairment (clinicaltrials.gov) - Jan 6, 2017
P=N/A, N=60, Active, not recruiting, Sponsor: Lawson Health Research Institute
Trial primary completion date: Feb 2016 --> May 2016 Trial primary completion date: Jun 2016 --> Jun 2017
- Trial completion, Enrollment change: Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. (clinicaltrials.gov) - Jan 6, 2017
P1, N=19, Completed, Sponsor: Institute for Neurodegenerative Disorders
Trial primary completion date: Jun 2016 --> Jun 2017 Recruiting --> Completed | N=80 --> 19
- Trial completion, Enrollment change, Trial primary completion date: FPEB: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (clinicaltrials.gov) - Jan 6, 2017
P1, N=48, Completed, Sponsor: Institute for Neurodegenerative Disorders
Recruiting --> Completed | N=80 --> 19 Recruiting --> Completed | N=155 --> 48 | Trial primary completion date: Dec 2015 --> Oct 2016
- Trial completion: Actigraphy to MEasuRe Intensive Care Unit Activity (clinicaltrials.gov) - Jan 6, 2017
P=N/A, N=25, Completed, Sponsor: Vanderbilt University
Recruiting --> Completed | N=155 --> 48 | Trial primary completion date: Dec 2015 --> Oct 2016 Active, not recruiting --> Completed
- Trial primary completion date: Tailored Activity Program-Veterans Affairs (clinicaltrials.gov) - Jan 5, 2017
P1, N=160, Active, not recruiting, Sponsor: VA Office of Research and Development
Active, not recruiting --> Completed Trial primary completion date: Nov 2015 --> Jun 2016
- ||| memantine / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, Combination therapy: Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease (clinicaltrials.gov) - Jan 4, 2017
P=N/A, N=3482, Completed, Sponsor: Eisai Co., Ltd.
Trial primary completion date: Nov 2015 --> Jun 2016 Active, not recruiting --> Completed | N=5000 --> 3482 | Trial primary completion date: Aug 2015 --> May 2015
- ||| donepezil / Generic mfg.
Trial completion: Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease (clinicaltrials.gov) - Jan 4, 2017
P=N/A, N=894, Completed, Sponsor: Eisai Co., Ltd.
Active, not recruiting --> Completed | N=5000 --> 3482 | Trial primary completion date: Aug 2015 --> May 2015 Active, not recruiting --> Completed
- ||| donepezil / Generic mfg.
Trial completion, Trial primary completion date: Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Factors That Affect Aricept Medication Persistence Rate and the Safety and Efficacy in Patients With Alzheimer's Disease in Clinical Practice (clinicaltrials.gov) - Dec 30, 2016
P=N/A, N=8662, Completed, Sponsor: Eisai Co., Ltd.
Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> May 2015
- ||| donepezil / Generic mfg.
Trial completion, Phase classification: Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease- (clinicaltrials.gov) - Dec 30, 2016
P=N/A, N=10238, Completed, Sponsor: Eisai Co., Ltd.
Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> May 2015 Active, not recruiting --> Completed | Phase classification: P4 --> PN/A
- quetiapine / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Efficacy of Quetiapine for Pediatric Delirium (clinicaltrials.gov) - Dec 28, 2016
P1/2, N=7, Terminated, Sponsor: Weill Medical College of Cornell University
Active, not recruiting --> Completed | Phase classification: P4 --> PN/A N=50 --> 7 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Dec 2016; Unable to recruit subjects at our site within the past year.
- ||| donepezil / Generic mfg.
Trial completion, Enrollment change: A Plan on Investigation and Collection of Aricept Safety Information With a Dose Increase on Alzheimer's Disease Patients (clinicaltrials.gov) - Dec 28, 2016
P=N/A, N=2231, Completed, Sponsor: Eisai Korea Inc.
N=50 --> 7 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Dec 2016; Unable to recruit subjects at our site within the past year. Recruiting --> Completed | N=6660 --> 2231
- ||||||| idalopirdine (Lu AE58054) / Otsuka, Eli Lilly, Denovo
Trial completion, Trial primary completion date: STARBEAM: Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil (clinicaltrials.gov) - Dec 23, 2016
P3, N=858, Completed, Sponsor: H. Lundbeck A/S
Recruiting --> Completed | N=6660 --> 2231 Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Dec 2016
- Trial completion, Trial primary completion date: Recollection Training in Healthy Older Adults and Older Adults With Amnestic Mild Cognitive Impairment (clinicaltrials.gov) - Dec 22, 2016
P=N/A, N=91, Completed, Sponsor: Baycrest
Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Mar 2012 --> Aug 2013
- Trial completion, Combination therapy: Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Dec 22, 2016
P4, N=330, Completed, Sponsor: Charite University, Berlin, Germany
Recruiting --> Completed | Trial primary completion date: Mar 2012 --> Aug 2013 Recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects (clinicaltrials.gov) - Dec 16, 2016
P1, N=16, Completed, Sponsor: Molecular NeuroImaging
Recruiting --> Completed Recruiting --> Completed | N=80 --> 16 | Trial primary completion date: Dec 2016 --> Aug 2016
- Trial completion: Efficacy and Safety of MNI-672 SPECT for Detection/Exclusion of Cerebral B-amyloid in AD Subjects Compared to HVs. (clinicaltrials.gov) - Dec 16, 2016
P1, N=6, Completed, Sponsor: Molecular NeuroImaging
Recruiting --> Completed | N=80 --> 16 | Trial primary completion date: Dec 2016 --> Aug 2016 Active, not recruiting --> Completed