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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- ||||| Enrollment closed: Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to Histopathology (clinicaltrials.gov) - Sep 8, 2011
P3, N=216, Active, not recruiting, Sponsor: Piramal Imaging SA
Recruiting --> Active, not recruiting
- Enrollment change: IMPROVE-ICU: International Multicenter Study One Day Prevalence Observational Study for Delirium on ICU (clinicaltrials.gov) - Sep 6, 2011
P=N/A, N=1002, Completed, Sponsor: Claudia Spies
Recruiting --> Active, not recruiting N=500 --> 1002
- Trial completion: ADNI: Alzheimer's Disease Neuroimaging Initiative (clinicaltrials.gov) - Sep 6, 2011
P=N/A, N=818, Completed, Sponsor: Alzheimer's Disease Cooperative Study (ADCS)
N=500 --> 1002 Active, not recruiting --> Completed
- ||||| ladostigil hemitartrate (TV-3326) / Avraham
New P2 trial: A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment (clinicaltrials.gov) - Sep 5, 2011
P2, N=200, Active, not recruiting, Sponsor: Avraham Pharmaceuticals Ltd
- Trial completion: Early Detection of Mild Cognitive Impairment in Individual Patients (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=34, Completed, Sponsor: Louisiana State University Health Sciences Center Shreveport
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| VI-1121 / IEH Biopharma
New P2 trial: VI-1121 for the Treatment Alzheimer's Disease (clinicaltrials.gov) - Sep 1, 2011
P2, N=61, Completed, Sponsor: VIVUS, Inc.
- ||||| rilapladib (SB-659032) / GSK
Biomarker, New P2 trial: A Phase 2a Study to Evaluate the Effect of Rilapladib (SB-659032) in Alzheimer's Disease (clinicaltrials.gov) - Sep 1, 2011
P2, N=124, Completed, Sponsor: GlaxoSmithKline
- Trial completion: WISDE: Effective Strategies for Dementia Care (clinicaltrials.gov) - Aug 29, 2011
P=N/A, N=327, Completed, Sponsor: Martin-Luther-Universität Halle-Wittenberg
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial termination: Incidence of Delirium in Hip Fracture Patients Randomized to Regular Hypnotics vs Placebo (clinicaltrials.gov) - Aug 28, 2011
P4, N=96, Terminated, Sponsor: Hvidovre University Hospital
Active, not recruiting --> Completed Recruiting --> Terminated; Slow inclusion resulting in premature termination due to logistics
- | GSK 933776 / GSK
New P1 trial: Modulation of Abeta Levels by GSK933776 in Alzheimer's Disease Patient (clinicaltrials.gov) - Aug 25, 2011
P1, N=19, Completed, Sponsor: GlaxoSmithKline
- |||||||||| Trintellix (vortioxetine) / Lundbeck, Takeda
New P3 trial: Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive Disorder (clinicaltrials.gov) - Aug 21, 2011
P3, N=598, Completed, Sponsor: H. Lundbeck A/S
- |||| donepezil / Generic mfg.
Trial completion: Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease (clinicaltrials.gov) - Aug 18, 2011
P2, N=210, Completed, Sponsor: Sonexa Therapeutics, Inc.
Recruiting --> Terminated; Slow inclusion resulting in premature termination due to logistics Active, not recruiting --> Completed
- ||||| itanapraced (CHF-5074) / CereSpir
New P2 trial: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP) (clinicaltrials.gov) - Aug 18, 2011
P2, N=74, Completed, Sponsor: Chiesi Pharmaceuticals Inc.
- | eltoprazine (DU 28853) / Amarantus BioSci, PsychoGenics, ReqMed
Enrollment open: Effects of Eltoprazine on Cognitive Impairment Associated With Schizophrenia (CIAS) in Adults (clinicaltrials.gov) - Aug 16, 2011
P2, N=50, Recruiting, Sponsor: PsychoGenics Inc.
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Telephone Call From Acute Care Physicians to Long Term Care Physicians: Impact on Transitional Care of Elderly Patients (clinicaltrials.gov) - Aug 16, 2011
P1, N=0, Completed, Sponsor: Maimonides Medical Center
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment open: Imaging of Cognition, Learning, and Memory in Aging (clinicaltrials.gov) - Aug 15, 2011
P=N/A, N=550, Recruiting, Sponsor: Yaakov Stern
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: SMARTease Trial: Evaluating Stroke Help Distance Interventions to Improve Cognitive Performance Post-Stroke (clinicaltrials.gov) - Aug 10, 2011
P3, N=10, Recruiting, Sponsor: Capital District Health Authority, Canada
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ponezumab (PF-04360365) / Pfizer
Trial completion: Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease (clinicaltrials.gov) - Aug 10, 2011
P1, N=8, Completed, Sponsor: Pfizer
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | cerlapirdine (PF-5212365) / Pfizer
Trial termination: Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease (clinicaltrials.gov) - Aug 9, 2011
P2, N=526, Terminated, Sponsor: Pfizer
Active, not recruiting --> Completed Active, not recruiting --> Terminated; See termination reason in detailed description.
- ||||||| semagacestat (LY450139) / Eli Lilly
Trial completion: IDENTITY-2: Effects of LY450139, on the Progression of Alzheimer's Disease as Compared With Placebo (clinicaltrials.gov) - Aug 9, 2011
P3, N=1100, Completed, Sponsor: Eli Lilly and Company
Active, not recruiting --> Terminated; See termination reason in detailed description. Active, not recruiting --> Completed
- |||| donepezil / Generic mfg.
Trial completion: Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease (clinicaltrials.gov) - Aug 8, 2011
P2, N=267, Completed, Sponsor: AbbVie (prior sponsor, Abbott)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | morphine sulphate / Generic mfg., pregabalin / Generic mfg., paracetamol / Generic mfg.
Trial completion: Pain in Patients With Dementia and Behavioural Disturbances (clinicaltrials.gov) - Aug 8, 2011
P2/3, N=352, Completed, Sponsor: University of Bergen
Active, not recruiting --> Completed Recruiting --> Completed
- Trial withdrawal: Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Alzheimer's Disease (clinicaltrials.gov) - Aug 7, 2011
P=N/A, N=80, Withdrawn, Sponsor: University Hospital, Basel, Switzerland
Recruiting --> Completed Not yet recruiting --> Withdrawn
- New P2 trial: CREST-X: Creatine Safety & Tolerability in Huntington's Disease (clinicaltrials.gov) - Aug 7, 2011
P2, N=10, Completed, Sponsor: Massachusetts General Hospital