|
122 Companies |
|
196 Products |
|
196 Products |
|
116 Mechanisms of Action |
|
3 Trials |
|
2338 News |
|
| «12...35363738394041424344454647» |
- ||||| New P4 trial: A Study to Evaluate Sleep Quality in Patients With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Nov 21, 2011
P4, N=925, Completed, Sponsor: Janssen-Cilag, S.A.
- | New P1/2 trial: The Talking Sense Communication Programme for Dementia Carers (clinicaltrials.gov) - Nov 21, 2011
P1/2, N=60, Recruiting, Sponsor: University of Portsmouth
- ||||||| Trial completion: Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07 (clinicaltrials.gov) - Nov 21, 2011
P3, N=110, Completed, Sponsor: Avid Radiopharmaceuticals
Active, not recruiting --> Completed
- | nelonicline (ABT-126) / AbbVie
New P1 trial: A Phase 1 Study of the Safety, Tolerability and Pharmacokinetics of ABT-126 in Subjects With Alzheimer's Disease (clinicaltrials.gov) - Nov 20, 2011
P1, N=20, Completed, Sponsor: Abbott
- ||| ASP 0777 / Astellas
Trial completion: A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil (clinicaltrials.gov) - Nov 16, 2011
P1, N=60, Completed, Sponsor: Astellas Pharma Inc
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | New P2 trial: Study of STA-1 Capsule in Patients With Vascular Dementia (Marrow-Sea Deficiency) (clinicaltrials.gov) - Nov 13, 2011
P2, N=240, Completed, Sponsor: Sinphar Pharmaceutical Co., Ltd
- bradanicline (ATA-101) / CODA Biotherap
Enrollment change: Multiple Ascending Dose Study of TC-5619 in Healthy Elderly Subjects and Subjects With Alzheimer's Disease (clinicaltrials.gov) - Nov 8, 2011
P1, N=38, Completed, Sponsor: Targacept Inc.
Active, not recruiting --> Completed N=54 --> 38
- | bradanicline (ATA-101) / CODA Biotherap
Trial completion: Multiple Ascending Dose Study of TC-5619 in Healthy Elderly Subjects and Subjects With Alzheimer's Disease (clinicaltrials.gov) - Nov 8, 2011
P1, N=38, Completed, Sponsor: Targacept Inc.
N=54 --> 38 Active, not recruiting --> Completed
- ||||| ispronicline (AZD3480) / AstraZeneca
New P2 trial, Monotherapy: Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD) (clinicaltrials.gov) - Nov 3, 2011
P2, N=300, Active, not recruiting, Sponsor: Targacept Inc.
- | velusetrag (TD-5108) / Innoviva
New P1 trial: Safety, Pharmacokinetics and Pharmacodynamics of Velusetrag in Healthy Elderly Subjects (clinicaltrials.gov) - Oct 27, 2011
P1, N=40, Completed, Sponsor: Theravance, Inc.
- rivastigmine / Generic mfg.
Trial completion: ADFRMI: Rivastigmine in Mild Alzheimer's Disease, FMRI Study (clinicaltrials.gov) - Oct 26, 2011
P=N/A, N=20, Completed, Sponsor: Kuopio University Hospital
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Clinical: Self-management and Cognitive Function in Adults With Heart Failure (clinicaltrials.gov) - Oct 25, 2011
P=N/A, N=400, Recruiting, Sponsor: Kent State University
- New P1 trial: Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls (clinicaltrials.gov) - Oct 25, 2011
P1, N=32, Active, not recruiting, Sponsor: Institute for Neurodegenerative Disorders
- Trial termination: Carbon Dioxide Insufflation on Cerebral Microemboli (clinicaltrials.gov) - Oct 24, 2011
P2/3, N=20, Terminated, Sponsor: University Health Network, Toronto
Active, not recruiting --> Completed Recruiting --> Terminated; ran out of funding
- Enrollment change: Carbon Dioxide Insufflation on Cerebral Microemboli (clinicaltrials.gov) - Oct 24, 2011
P2/3, N=20, Terminated, Sponsor: University Health Network, Toronto
Recruiting --> Terminated; ran out of funding N=100 --> 20
- HEOR: Comparative Effectiveness of Dementia Care Strategies in Underserved Communities (clinicaltrials.gov) - Oct 24, 2011
P=N/A, N=250, Enrolling by invitation, Sponsor: RAND
- Enrollment change: Evaluation of the Diagnostic Potential of BAY1006578 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of BAY1006578 in Healthy Volunteers (clinicaltrials.gov) - Oct 24, 2011
P1, N=24, Completed, Sponsor: Piramal Imaging SA
N=100 --> 20 N=36 --> 24
- | minocycline / Generic mfg.
New P2 trial: Minocycline in Patients With Alzheimer's Disease (clinicaltrials.gov) - Oct 24, 2011
P2, N=120, Recruiting, Sponsor: Huntington Medical Research Institutes
- | Trial completion: Evaluation of the Diagnostic Potential of BAY1006578 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of BAY1006578 in Healthy Volunteers (clinicaltrials.gov) - Oct 24, 2011
P1, N=24, Completed, Sponsor: Piramal Imaging SA
N=36 --> 24 Recruiting --> Completed
- Enrollment open: CBTAC: Cognitive-Behavioral Treatment for Mild Alzheimer's Patients and Their Caregivers (clinicaltrials.gov) - Oct 23, 2011
P2, N=124, Recruiting, Sponsor: University of Zurich
Recruiting --> Completed Not yet recruiting --> Recruiting
- ||| Biomarker, New P1 trial: A Non-drug Methods Study in Participants With Alzheimer's Disease (clinicaltrials.gov) - Oct 23, 2011
P1, N=196, Active, not recruiting, Sponsor: Eli Lilly and Company
- ||| donepezil / Generic mfg.
Enrollment closed: Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease- (clinicaltrials.gov) - Oct 19, 2011
P4, N=10000, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- | amisulpride / Generic mfg.
New P4 trial: Optimisation of Antipsychotic Drug Use in Older People (clinicaltrials.gov) - Oct 17, 2011
P4, N=120, Recruiting, Sponsor: Institute of Psychiatry, London
- ||||| Nine Phase One (mannote sodium) / Shanghai Greenvalley
New P2 trial: Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Oct 16, 2011
P2, N=252, Active, not recruiting, Sponsor: Shanghai Greenvalley Pharmaceutical Co., Ltd.
- | tetrabenazine / Generic mfg.
New P4 trial: Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease (clinicaltrials.gov) - Oct 11, 2011
P4, N=15, Completed, Sponsor: Ohio State University
- Clinical: Health Technology Assessment of Diagnostic Approaches in Alzheimer's Disease (clinicaltrials.gov) - Oct 10, 2011
P=N/A, N=200, Recruiting, Sponsor: Maastricht University Medical Center
- |||||||||| donepezil / Generic mfg.
New P3 trial: Efficacy and Safety Study of Shenwu Capsule (clinicaltrials.gov) - Oct 10, 2011
P3, N=324, Completed, Sponsor: North China Pharmaceutical Group Corporation
- | memantine / Generic mfg.
Enrollment open: AD-IDEA: Alzheimer's Disease - Input of Vitamin D With mEmantine Assay (clinicaltrials.gov) - Oct 10, 2011
P3, N=120, Recruiting, Sponsor: University Hospital, Angers
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- |||| donepezil / Generic mfg.
Trial completion: A Long-term, Extension Study of E2020 in Patients With Dementia With Lewy Bodies (clinicaltrials.gov) - Oct 10, 2011
P2, N=160, Completed, Sponsor: Eisai Co., Ltd.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||| avagacestat (BMS-708163) / BMS
New P1 trial: Study to Evaluate the Safety, Pharmacokinetics and Tolerability of BMS-708163 (clinicaltrials.gov) - Oct 6, 2011
P1, N=116, Completed, Sponsor: Bristol-Myers Squibb
- Trial completion: The Occurrence of the ApoE4 Allele in Agitated In-Patients With Late-Onset Alzheimer's Disease (clinicaltrials.gov) - Oct 4, 2011
P=N/A, N=50, Completed, Sponsor: Avera McKennan Hospital & University Health Center
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion: A Study to Compare Genetic Variations of IGF-I and IGF-II (clinicaltrials.gov) - Oct 4, 2011
P=N/A, N=50, Completed, Sponsor: Avera McKennan Hospital & University Health Center
Recruiting --> Completed Recruiting --> Completed
- |||||||||| New P3 trial: Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07 (clinicaltrials.gov) - Oct 4, 2011
P3, N=110, Completed, Sponsor: Avid Radiopharmaceuticals
- Enrollment change: ORGAR: Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness (clinicaltrials.gov) - Oct 3, 2011
P2/3, N=34, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting --> Completed N=49 --> 34
- Enrollment closed: Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL) (clinicaltrials.gov) - Oct 3, 2011
P2, N=90, Active, not recruiting, Sponsor: Huntington Study Group
N=49 --> 34 Recruiting --> Active, not recruiting
- |||| intepirdine (SB-742457) / Roivant
Trial completion: A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease (clinicaltrials.gov) - Oct 3, 2011
P2, N=684, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Trial completion: ORGAR: Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness (clinicaltrials.gov) - Oct 3, 2011
P2/3, N=34, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, MRI: Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) (clinicaltrials.gov) - Sep 27, 2011
P=N/A, N=60, Completed, Sponsor: University of Wisconsin, Madison
Recruiting --> Completed Recruiting --> Completed
- |||| memantine / Generic mfg.
Trial completion: Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems (clinicaltrials.gov) - Sep 25, 2011
P2, N=299, Completed, Sponsor: Merz Pharmaceuticals GmbH
Recruiting --> Completed Active, not recruiting --> Completed
- mavoglurant (AFQ056) / Novartis
Trial termination: Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea (clinicaltrials.gov) - Sep 21, 2011
P2, N=44, Terminated, Sponsor: Novartis Pharmaceuticals
Active, not recruiting --> Completed Recruiting --> Terminated
- mavoglurant (AFQ056) / Novartis
Enrollment change, Journal: Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing Chorea (clinicaltrials.gov) - Sep 21, 2011
P2, N=44, Terminated, Sponsor: Novartis Pharmaceuticals
Recruiting --> Terminated N=60 --> 44
- atorvastatin / Generic mfg.
Enrollment change: Modulation of Monocyte Activation by Atorvastatin in HIV Infection (clinicaltrials.gov) - Sep 20, 2011
P4, N=15, Active, not recruiting, Sponsor: University of Pennsylvania
N=60 --> 44 N=20 --> 15
- |||||||||| aripiprazole / Generic mfg.
New P3 trial: Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of Alzheimer's Type (clinicaltrials.gov) - Sep 19, 2011
P3, N=232, Completed, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
- Enrollment change: A Study to Evaluate the Use of an Indwelling Catheter to Obtain Cerebrospinal Fluid (CSF) by Low-rate Continuous Sampling (MK-0000-211) (clinicaltrials.gov) - Sep 18, 2011
P=N/A, N=11, Completed, Sponsor: Merck Sharp & Dohme Corp.
N=20 --> 15 N=30 --> 11
- | Trial completion: A Study to Evaluate the Use of an Indwelling Catheter to Obtain Cerebrospinal Fluid (CSF) by Low-rate Continuous Sampling (MK-0000-211) (clinicaltrials.gov) - Sep 18, 2011
P=N/A, N=11, Completed, Sponsor: Merck Sharp & Dohme Corp.
N=30 --> 11 Active, not recruiting --> Completed
- Trial completion: Improving Decision Making About Feeding Options for Dementia (clinicaltrials.gov) - Sep 18, 2011
P=N/A, N=256, Completed, Sponsor: University of North Carolina, Chapel Hill
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Apidra (insulin glulisine) / Sanofi
New P2 trial: Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients. (clinicaltrials.gov) - Sep 15, 2011
P2, N=12, Active, not recruiting, Sponsor: HealthPartners Institute for Education and Research
- Enrollment closed: Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids (clinicaltrials.gov) - Sep 12, 2011
P=N/A, N=50, Active, not recruiting, Sponsor: New York University School of Medicine
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- memantine / Generic mfg.
Trial termination: MemAP: Memantine and Antipsychotics Use (clinicaltrials.gov) - Sep 11, 2011
P4, N=19, Terminated, Sponsor: Merz Pharmaceuticals GmbH
Recruiting --> Active, not recruiting Completed --> Terminated; Study terminated due to too slow enrollment
- memantine / Generic mfg.
Enrollment change: MemAP: Memantine and Antipsychotics Use (clinicaltrials.gov) - Sep 11, 2011
P4, N=19, Terminated, Sponsor: Merz Pharmaceuticals GmbH
Completed --> Terminated; Study terminated due to too slow enrollment N=27 --> 19