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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- isoflurane / Generic mfg.
New P1 trial: MAD-PIA: Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia (clinicaltrials.gov) - Jul 11, 2012
P1, N=100, Recruiting, Sponsor: Duke University
- New P2 trial: 2-STEP: Thinking, Walking Outcomes by Type of Exercise (clinicaltrials.gov) - Jul 5, 2012
P2, N=24, Recruiting, Sponsor: University of Pittsburgh
- ||| Trial completion: Performance of AclarusDx (clinicaltrials.gov) - Jul 3, 2012
P=N/A, N=160, Completed, Sponsor: Exonhit
Recruiting --> Completed
- | donepezil / Generic mfg.
New P4 trial: Treatment of Delirium in the Elderly With Donepezil: a Double-blind, Randomized, Placebo-controlled Clinical Trial (clinicaltrials.gov) - Jul 2, 2012
P4, N=190, Not yet recruiting, Sponsor: University of Sao Paulo
- Trial completion: Effects of Involvement in a Group-based Creative Expression Program on Psychotropic Drug Use in Persons With Dementia (clinicaltrials.gov) - Jul 2, 2012
P=N/A, N=20, Completed, Sponsor: Milton S. Hershey Medical Center
Recruiting --> Completed Active, not recruiting --> Completed
- | Enrollment closed: 2CARE: Coenzyme Q10 in Huntington's Disease (HD) (clinicaltrials.gov) - Jul 1, 2012
P3, N=608, Active, not recruiting, Sponsor: Massachusetts General Hospital
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||||||| solanezumab (LY2062430) / Eli Lilly
Trial completion: EXPEDITION2: Effect of LY2062430 on the Progression of Alzheimer's Disease (clinicaltrials.gov) - Jun 27, 2012
P3, N=1040, Completed, Sponsor: Eli Lilly and Company
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Aduhelm (aducanumab) / Eisai, Biogen
Enrollment change: Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease (clinicaltrials.gov) - Jun 27, 2012
P1, N=48, Active, not recruiting, Sponsor: Biogen Idec
Active, not recruiting --> Completed N=40 --> 48
- New P1 trial: U-SMART: Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (clinicaltrials.gov) - Jun 25, 2012
P1, N=10, Completed, Sponsor: Seoul National University Bundang Hospital
- Enrollment open: Dual Task Aerobic Exercise for Older Adults With Cognitive Impairment (HM2) (clinicaltrials.gov) - Jun 24, 2012
P=N/A, N=126, Recruiting, Sponsor: Parkwood Hospital, London, Ontario
N=40 --> 48 Not yet recruiting --> Recruiting
- Trial completion: CJD (Creutzfeldt-Jakob Disease) Quinacrine Study (clinicaltrials.gov) - Jun 24, 2012
P2, N=69, Completed, Sponsor: University of California, San Francisco
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Trial completion: MAIN: Memory and Insulin in Early Alzheimer's Disease (clinicaltrials.gov) - Jun 21, 2012
P2, N=30, Completed, Sponsor: Jeff Burns, MD
Active, not recruiting --> Completed Active, not recruiting --> Completed
- LMTX (hydromethylthionine) / TauRx
New P2 trial: Safety Study of TRx0237 in Patients Already Taking Medications for Mild and Moderate Alzheimer's Disease (clinicaltrials.gov) - Jun 20, 2012
P2, N=9, Terminated, Sponsor: TauRx Therapeutics Ltd
- |||||||||| LMTX (hydromethylthionine) / TauRx
New P3 trial: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD) (clinicaltrials.gov) - Jun 20, 2012
P3, N=180, Recruiting, Sponsor: TauRx Therapeutics Ltd
- Trial initiation date: Delirium in Mechanically Ventilated Patients (clinicaltrials.gov) - Jun 18, 2012
P=N/A, N=150, Recruiting, Sponsor: University of Chicago
Active, not recruiting --> Completed Initiation date: Jun 2009 --> Jun 2010
- Enrollment closed: Memantine and Comprehensive, Individualized Management of Alzheimer's Disease and Caregiver Training (clinicaltrials.gov) - Jun 17, 2012
P4, N=20, Active, not recruiting, Sponsor: New York University School of Medicine
Initiation date: Jun 2009 --> Jun 2010 Recruiting --> Active, not recruiting
- Enrollment open: PC-DATA: The Primary Care - Dementia Assessment and Treatment Algorithm (clinicaltrials.gov) - Jun 15, 2012
P=N/A, N=135, Recruiting, Sponsor: Queen's University
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Enrollment change: HIP: Hormone and Information Processing Study (clinicaltrials.gov) - Jun 14, 2012
P3, N=23, Completed, Sponsor: University of Washington
Not yet recruiting --> Recruiting N=12 --> 23
- Trial completion: HIP: Hormone and Information Processing Study (clinicaltrials.gov) - Jun 14, 2012
P3, N=23, Completed, Sponsor: University of Washington
N=12 --> 23 Recruiting --> Completed
- Enrollment open, Metastases: Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia (clinicaltrials.gov) - Jun 13, 2012
P=N/A, N=300, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment change: TEAM: Trial of a Medical and Mental Health Unit for Older People (clinicaltrials.gov) - Jun 11, 2012
P=N/A, N=600, Completed, Sponsor: University of Nottingham
Not yet recruiting --> Recruiting N=480 --> 600
- Trial completion: TEAM: Trial of a Medical and Mental Health Unit for Older People (clinicaltrials.gov) - Jun 11, 2012
P=N/A, N=600, Completed, Sponsor: University of Nottingham
N=480 --> 600 Recruiting --> Completed
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
New P1/2 trial: FFAD: Efficacy and Safety of Filgrastim in Alzheimer's Disease (clinicaltrials.gov) - Jun 10, 2012
P1/2, N=8, Completed, Sponsor: University of South Florida
- Trial completion: Person- Centred Care Among Nursing Home Patients With Dementia (clinicaltrials.gov) - Jun 10, 2012
P=N/A, N=624, Completed, Sponsor: Norwegian Centre for Ageing and Health
Recruiting --> Completed Enrolling by invitation --> Completed
- |||||||||| rivastigmine transdermal / Generic mfg.
New P3 trial: Randomized, Double-blind Study to Evaluate the Tolerability of 2 Different Titration Methods of Rivastigmine Patch in AD Patients (MMSE 10-20) (clinicaltrials.gov) - Jun 6, 2012
P3, N=101, Active, not recruiting, Sponsor: Novartis Pharmaceuticals
- Trial termination: [18F]MK-3328 as a Possible Novel Positron Emission Tomography (PET) Tracer for the Detection of Brain Amyloid Plaques (MK-3328-002) (clinicaltrials.gov) - Jun 6, 2012
P1, N=20, Terminated, Sponsor: Merck Sharp & Dohme Corp.
Enrolling by invitation --> Completed Active, not recruiting --> Terminated
- || memantine / Generic mfg.
Trial completion, FDG PET: Open Label Pilot Study of the Effects of Memantine on FDG-PET in Frontotemporal Dementia (clinicaltrials.gov) - May 31, 2012
P3, N=17, Completed, Sponsor: Tiffany Chow, MD
Active, not recruiting --> Terminated Active, not recruiting --> Completed
- | paracetamol / Generic mfg., dronabinol oral / Generic mfg.
New P2 trial: Delta-THC in Dementia (clinicaltrials.gov) - May 29, 2012
P2, N=150, Recruiting, Sponsor: Radboud University
- Trial termination: Early Intervention in Mild Cognitive Impairment (MCI) With Curcumin + Bioperine (clinicaltrials.gov) - May 24, 2012
P=N/A, N=10, Terminated, Sponsor: Louisiana State University Health Sciences Center Shreveport
Active, not recruiting --> Completed Completed --> Terminated; For various reasons.
- | Trial completion, Enrollment change: The Development of Categorization (clinicaltrials.gov) - May 23, 2012
P=N/A, N=219, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed --> Terminated; For various reasons. N=408 --> 219 | Recruiting --> Completed
- Trial completion: The Development of Categorization (clinicaltrials.gov) - May 23, 2012
P=N/A, N=219, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
N=408 --> 219 | Recruiting --> Completed Recruiting --> Completed
- Clinical: Mindfulness Based Stress Reduction for Adults With Mild Cognitive Impairment (clinicaltrials.gov) - May 22, 2012
P=N/A, N=14, Completed, Sponsor: Beth Israel Deaconess Medical Center
- Vyvanse (lisdexamfetamine) / Shionogi, Takeda
Trial completion: Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome (clinicaltrials.gov) - May 22, 2012
P4, N=26, Completed, Sponsor: Rochester Center for Behavioral Medicine
Recruiting --> Completed Recruiting --> Completed
- ||||| itanapraced (CHF-5074) / CereSpir
New P2 trial: CT04 POLEP: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase (clinicaltrials.gov) - May 17, 2012
P2, N=51, Completed, Sponsor: Chiesi Pharmaceuticals Inc.
- GSK356278 / GSK
New P1 trial: Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease (clinicaltrials.gov) - May 17, 2012
P1, N=8, Completed, Sponsor: GlaxoSmithKline
- acetylcysteine solution / Generic mfg.
Enrollment change: N-acetylcysteine and NMDA Antagonist Interactions (clinicaltrials.gov) - May 16, 2012
P1/2, N=16, Completed, Sponsor: Yale University
Recruiting --> Completed N=20 --> 16
- |||| itanapraced (CHF-5074) / CereSpir
Trial completion: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 (clinicaltrials.gov) - May 16, 2012
P2, N=96, Completed, Sponsor: Chiesi Pharmaceuticals Inc.
N=20 --> 16 Active, not recruiting --> Completed
- acetylcysteine solution / Generic mfg.
Trial completion: N-acetylcysteine and NMDA Antagonist Interactions (clinicaltrials.gov) - May 16, 2012
P1/2, N=16, Completed, Sponsor: Yale University
Active, not recruiting --> Completed Recruiting --> Completed
- GSK 933776 / GSK
Enrollment change: Modulation of Abeta Levels by GSK933776 in Alzheimer's Disease Patient (clinicaltrials.gov) - May 16, 2012
P1, N=19, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed N=35 --> 19
- | GSK 933776 / GSK
Trial completion: Modulation of Abeta Levels by GSK933776 in Alzheimer's Disease Patient (clinicaltrials.gov) - May 16, 2012
P1, N=19, Completed, Sponsor: GlaxoSmithKline
N=35 --> 19 Active, not recruiting --> Completed
- citalopram / Generic mfg.
Trial completion: CIT-HD: Citalopram to Enhance Cognition in HD (clinicaltrials.gov) - May 16, 2012
P2, N=33, Completed, Sponsor: University of Iowa
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | New P2 trial: NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease (clinicaltrials.gov) - May 15, 2012
P2, N=86, Completed, Sponsor: Chang Gung Memorial Hospital
- Clinical: Effects of Antimuscarinics on Cognition in Spinal Cord Injury (clinicaltrials.gov) - May 15, 2012
P=N/A, N=40, Recruiting, Sponsor: Swiss Paraplegic Centre Nottwil
- ||| elenbecestat (E2609) / Eisai, Biogen
New P1 trial: Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02) (clinicaltrials.gov) - May 15, 2012
P1, N=65, Completed, Sponsor: Eisai Inc.
- |||| rivastigmine transdermal / Generic mfg.
Trial completion: A 12 Week, Multicenter, Open Label Evaluation of Caregiver Preference, Safety and Tolerability of Exelon® Patch (Rivastigmine Transdermal) in Patients With Alzheimer's Disease (clinicaltrials.gov) - May 14, 2012
P4, N=51, Completed, Sponsor: Novartis Pharmaceuticals
Active, not recruiting --> Completed Recruiting --> Completed
- ||||||| solanezumab (LY2062430) / Eli Lilly
Trial completion: EXPEDITION: Effect of LY2062430 on the Progression of Alzheimer's Disease (clinicaltrials.gov) - May 13, 2012
P3, N=1000, Completed, Sponsor: Eli Lilly and Company
Recruiting --> Completed Active, not recruiting --> Completed
- pitavastatin / Generic mfg.
Trial termination: PIT-ROAD: The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - May 13, 2012
P=N/A, N=38, Terminated, Sponsor: Osaka University
Active, not recruiting --> Completed Active, not recruiting --> Terminated
- pitavastatin / Generic mfg.
Enrollment change: PIT-ROAD: The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - May 13, 2012
P=N/A, N=38, Terminated, Sponsor: Osaka University
Active, not recruiting --> Terminated N=50 --> 38
- sevoflurane / Generic mfg.
Enrollment closed: POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia (clinicaltrials.gov) - May 9, 2012
P=N/A, N=100, Active, not recruiting, Sponsor: Loma Linda University
N=50 --> 38 Recruiting --> Active, not recruiting
- New P1/2 trial: COST-TBI: Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury (clinicaltrials.gov) - May 9, 2012
P1/2, N=24, Recruiting, Sponsor: Boston Medical Center