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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- aripiprazole / Generic mfg., risperidone / Generic mfg., olanzapine / Generic mfg.
Trial completion, Adverse events: Side Effects of Newer Antipsychotics in Older Adults (clinicaltrials.gov) - Oct 16, 2012
P4, N=406, Completed, Sponsor: Veterans Medical Research Foundation
Recruiting --> Completed
- Enrollment open, Metastases: Palliative and End-of-life Care in Advanced Dementia: Evaluation of a Program of Organization of Care in Long-term Care (clinicaltrials.gov) - Oct 16, 2012
P=N/A, N=175, Recruiting, Sponsor: Laval University
Recruiting --> Completed Not yet recruiting --> Recruiting
- Surgery: Role of Cerebral Oximetry In Reducing Delirium After Complex Cardiac Surgery (clinicaltrials.gov) - Oct 14, 2012
P=N/A, N=266, Recruiting, Sponsor: University Health Network, Toronto
- trazodone ER / Generic mfg.
Trial completion: Trazodone for Sleep Disorders in Alzheimer's Disease (clinicaltrials.gov) - Oct 11, 2012
P3, N=40, Completed, Sponsor: Brasilia University Hospital
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||| donepezil / Generic mfg.
Enrollment closed: Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease (clinicaltrials.gov) - Oct 10, 2012
P4, N=1000, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- | Trial completion: TEAM-AD: A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease (clinicaltrials.gov) - Oct 10, 2012
P3, N=613, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||| davunetide intranasal (AL-108) / Endo
Enrollment change: Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment (clinicaltrials.gov) - Oct 9, 2012
P2, N=144, Completed, Sponsor: Allon Therapeutics
Active, not recruiting --> Completed N=120 --> 144
- ||||| New P4 trial: Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline (clinicaltrials.gov) - Oct 8, 2012
P4, N=600, Active, not recruiting, Sponsor: Avid Radiopharmaceuticals
- Enrollment change: BIOMAGE: Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease (clinicaltrials.gov) - Oct 7, 2012
P=N/A, N=60, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
N=120 --> 144 N=100 --> 60
- Trial completion: BIOMAGE: Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease (clinicaltrials.gov) - Oct 7, 2012
P=N/A, N=60, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
N=100 --> 60 Recruiting --> Completed
- ||| GSK2981710 / GSK
New P1 trial: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - Oct 4, 2012
P1, N=88, Recruiting, Sponsor: GlaxoSmithKline
- | GSK2647544 / GSK
New P1 trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single, Oral Escalating Doses of GSK2647544 in Healthy Volunteers (clinicaltrials.gov) - Oct 4, 2012
P1, N=27, Completed, Sponsor: GlaxoSmithKline
- sevoflurane / Generic mfg.
New P1/2 trial: Optimization of Desflurane in Elderly Patients (clinicaltrials.gov) - Oct 2, 2012
P1/2, N=0, Active, not recruiting, Sponsor: Sapporo Medical University
- pioglitazone / Generic mfg.
Enrollment closed: POEM: Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Oct 2, 2012
P2, N=300, Active, not recruiting, Sponsor: University of Colorado, Denver
Recruiting --> Completed Recruiting --> Active, not recruiting
- | sembragiline (RO4602522) / Roche, Evotec
New P1 trial: A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers (clinicaltrials.gov) - Oct 2, 2012
P1, N=17, Completed, Sponsor: Hoffmann-La Roche
- Trial completion: Effects of Delivery Mode of Cognition Intervention in Early Alzheimer's Disease (clinicaltrials.gov) - Oct 1, 2012
P2, N=25, Completed, Sponsor: University of Kansas
Recruiting --> Active, not recruiting Enrolling by invitation --> Completed
- |||| Trial completion: ARGO: Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients (clinicaltrials.gov) - Sep 30, 2012
P2, N=306, Completed, Sponsor: Noscira SA
Enrolling by invitation --> Completed Active, not recruiting --> Completed
- Enrollment change: Delirium in Mechanically Ventilated Patients (clinicaltrials.gov) - Sep 27, 2012
P=N/A, N=150, Recruiting, Sponsor: University of Chicago
Active, not recruiting --> Completed N=100 --> 150
- | rivastigmine / Generic mfg.
New P2 trial: Efficacy and Tolerability of MLC601 in Patients With Mild to Moderate Alzheimer Disease Who Were Unable to Tolerate or Failed to Benefit From Treatment With Rivastigmine (clinicaltrials.gov) - Sep 26, 2012
P2, N=125, Completed, Sponsor: Shaheed Beheshti Medical University
- Biomarker, Enrollment change: Research of Biomarkers in Parkinson Disease (clinicaltrials.gov) - Sep 25, 2012
P0, N=219, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
N=100 --> 150 N=1150 --> 219
- Biomarker, Trial completion: Research of Biomarkers in Parkinson Disease (clinicaltrials.gov) - Sep 25, 2012
P0, N=219, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
N=1150 --> 219 Recruiting --> Completed
- | ponezumab (PF-04360365) / Pfizer
Trial completion: Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers (clinicaltrials.gov) - Sep 24, 2012
P1, N=17, Completed, Sponsor: Pfizer
Recruiting --> Completed Active, not recruiting --> Completed
- Trial initiation date: Tailored Activity Program-Veterans Affairs (clinicaltrials.gov) - Sep 23, 2012
P1, N=160, Recruiting, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Initiation date: Apr 2012 --> Aug 2012
- Enrollment open: Tailored Activity Program-Veterans Affairs (clinicaltrials.gov) - Sep 23, 2012
P1, N=160, Recruiting, Sponsor: Department of Veterans Affairs
Initiation date: Apr 2012 --> Aug 2012 Not yet recruiting --> Recruiting
- || ketamine / Generic mfg.
New P3 trial: PODCAST: The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial (clinicaltrials.gov) - Sep 20, 2012
P3, N=600, Recruiting, Sponsor: Washington University School of Medicine
- Trial completion: e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems (clinicaltrials.gov) - Sep 19, 2012
P=N/A, N=424, Completed, Sponsor: Regenstrief Institute, IU Center for Aging Research
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- |||||||||| LMTX (hydromethylthionine) / TauRx
New P3 trial: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Sep 19, 2012
P3, N=833, Recruiting, Sponsor: TauRx Therapeutics Ltd
- |||||||||| LMTX (hydromethylthionine) / TauRx
New P3 trial: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease (clinicaltrials.gov) - Sep 19, 2012
P3, N=700, Recruiting, Sponsor: TauRx Therapeutics Ltd
- Enrollment open: COST-TBI: Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury (clinicaltrials.gov) - Sep 19, 2012
P1/2, N=24, Recruiting, Sponsor: Boston Medical Center
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Aduhelm (aducanumab) / Eisai, Biogen
Enrollment closed: Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease (clinicaltrials.gov) - Sep 19, 2012
P1, N=48, Active, not recruiting, Sponsor: Biogen Idec
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- New P3 trial: Efficacy of Ubiquitous SR-based Memory Advancement and Rehabilitation Training (U-SMART) (clinicaltrials.gov) - Sep 17, 2012
P3, N=50, Recruiting, Sponsor: Seoul National University Bundang Hospital
- midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
Metastases: Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients (clinicaltrials.gov) - Sep 17, 2012
P2, N=20, Recruiting, Sponsor: Fraser Health
- New P4 trial, HEOR: Effect of VSL#3 (Original De Simone Formulation) on Cognitive Function, Risk of Falls and Quality of Life in Patients With Cirrhosis (clinicaltrials.gov) - Sep 16, 2012
P4, N=40, Recruiting, Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- |||| sembragiline (RO4602522) / Roche, Evotec
Enrollment open: MAyflOwer RoAD: A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy (clinicaltrials.gov) - Sep 13, 2012
P2, N=495, Recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Trial termination: A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients (clinicaltrials.gov) - Sep 11, 2012
P3, N=493, Terminated, Sponsor: Pfizer
Recruiting --> Terminated; The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Trial termination: A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients (clinicaltrials.gov) - Sep 11, 2012
P3, N=198, Terminated, Sponsor: Pfizer
Recruiting --> Terminated; The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Trial termination: Study Evaluating The Long-Term Safety And Efficacy Of Subcutaneous Bapineuzumab (clinicaltrials.gov) - Sep 11, 2012
P2, N=66, Terminated, Sponsor: Pfizer
Active, not recruiting --> Terminated; The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Trial termination: Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients (clinicaltrials.gov) - Sep 11, 2012
P3, N=1099, Terminated, Sponsor: Pfizer
Active, not recruiting --> Terminated; The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Trial termination: Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients (clinicaltrials.gov) - Sep 11, 2012
P3, N=835, Terminated, Sponsor: Pfizer
Recruiting --> Terminated; The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.
- | bapineuzumab (AAB-001) / Pfizer, J&J, Perrigo Company
Enrollment change: A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients (clinicaltrials.gov) - Sep 11, 2012
P3, N=198, Terminated, Sponsor: Pfizer
This decision was not based on any new safety concerns. N=1000 --> 198
- Enrollment change: Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers (clinicaltrials.gov) - Sep 11, 2012
P=N/A, N=814, Completed, Sponsor: University of Pennsylvania
N=1000 --> 198 N=420 --> 814
- Trial completion: SNIFF 120: Study of Nasal Insulin to Fight Forgetfulness (120 Days) (clinicaltrials.gov) - Sep 11, 2012
P2, N=173, Completed, Sponsor: University of Washington
N=420 --> 814 Active, not recruiting --> Completed
- Trial completion: Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers (clinicaltrials.gov) - Sep 11, 2012
P=N/A, N=814, Completed, Sponsor: University of Pennsylvania
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Biomarker, Enrollment open: Improving Dementia Caregiver Sleep & the Effect on Heart Disease Biomarkers (clinicaltrials.gov) - Sep 10, 2012
P=N/A, N=80, Recruiting, Sponsor: University of South Florida
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Deep Brain Stimulation of the Globus Pallidus in Huntington's Disease (clinicaltrials.gov) - Sep 9, 2012
P1, N=6, Completed, Sponsor: Heinrich-Heine University, Duesseldorf
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- || New P3 trial, HEOR: ADEX: Effect of Physical Exercise in Alzheimer Patients (clinicaltrials.gov) - Sep 6, 2012
P3, N=192, Recruiting, Sponsor: Rigshospitalet, Denmark
- ||||| sembragiline (RO4602522) / Roche, Evotec
New P2 trial: MAyflOwer RoAD: A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy (clinicaltrials.gov) - Aug 30, 2012
P2, N=495, Recruiting, Sponsor: Hoffmann-La Roche
- | memantine / Generic mfg.
Trial completion: Study on Cognitive Disorders of Multiple Sclerosis (clinicaltrials.gov) - Aug 30, 2012
P3, N=90, Completed, Sponsor: University Hospital, Caen
Active, not recruiting --> Completed Active, not recruiting --> Completed
- levetiracetam / Generic mfg.
Trial completion, Preclinical: Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Aug 29, 2012
P2, N=144, Completed, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed Recruiting --> Completed
- || divalproex sodium XR / Generic mfg., quetiapine / Generic mfg.
Trial completion: Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia (clinicaltrials.gov) - Aug 29, 2012
P3, N=20, Completed, Sponsor: Tuscaloosa Research & Education Advancement Corporation
Recruiting --> Completed Recruiting --> Completed