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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- Trial primary completion date: 18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) - Sep 15, 2017
P1, N=10, Recruiting, Sponsor: Avid Radiopharmaceuticals
Trial primary completion date: Jun 2017 --> Oct 2017
- ziprasidone mesylate injection / Generic mfg.
Enrollment change, Trial withdrawal, Trial primary completion date: Ziprasidone vs Standard Therapy for Agitated Patients in the ED (clinicaltrials.gov) - Sep 13, 2017
P4, N=0, Withdrawn, Sponsor: George Washington University
Trial primary completion date: Jun 2017 --> Oct 2017 N=300 --> 0 | Active, not recruiting --> Withdrawn | Trial primary completion date: Jan 2010 --> Jul 2011
- | Trial completion, Trial primary completion date: Dance and Huntington Disease (clinicaltrials.gov) - Sep 13, 2017
P=N/A, N=53, Completed, Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
N=300 --> 0 | Active, not recruiting --> Withdrawn | Trial primary completion date: Jan 2010 --> Jul 2011 Not yet recruiting --> Completed | Trial primary completion date: Feb 2015 --> Jul 2015
- | Trial completion, Enrollment change, Trial primary completion date: Wii-Fit For Improving Activity, Gait And Balance In Alzheimer's Dementia (clinicaltrials.gov) - Sep 6, 2017
P=N/A, N=22, Completed, Sponsor: University of Nebraska
Not yet recruiting --> Completed | Trial primary completion date: Feb 2015 --> Jul 2015 Recruiting --> Completed | N=30 --> 22 | Trial primary completion date: Oct 2011 --> Oct 2012
- | Trial completion, Enrollment change, Trial primary completion date: AIDALZ: Effectiveness of Care Management in Alzheimer Patients (clinicaltrials.gov) - Aug 28, 2017
P=N/A, N=270, Completed, Sponsor: Institut de Sante Publique, d'Epidemiologie et de Developpement
Recruiting --> Completed | N=30 --> 22 | Trial primary completion date: Oct 2011 --> Oct 2012 Recruiting --> Completed | N=400 --> 270 | Trial primary completion date: Dec 2011 --> Oct 2013
- | Trial completion: Post-Operative Delirium in Elderly Surgical Patients (clinicaltrials.gov) - Aug 24, 2017
P=N/A, N=200, Completed, Sponsor: Johns Hopkins University
Recruiting --> Completed | N=400 --> 270 | Trial primary completion date: Dec 2011 --> Oct 2013 Active, not recruiting --> Completed
- | modafinil / Generic mfg.
Trial primary completion date: Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder With Modafinil (clinicaltrials.gov) - Aug 22, 2017
P4, N=48, Recruiting, Sponsor: Icahn School of Medicine at Mount Sinai
Active, not recruiting --> Completed Trial primary completion date: Sep 2017 --> Dec 2017
- | Trial completion, Enrollment change, Metastases: Cognitive Impairment in Kidney Disease (clinicaltrials.gov) - Aug 18, 2017
P=N/A, N=117, Completed, Sponsor: VA Office of Research and Development
Trial primary completion date: Sep 2017 --> Dec 2017 Active, not recruiting --> Completed | N=190 --> 117
- | amantadine / Generic mfg.
Enrollment change, Trial withdrawal: Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD) (clinicaltrials.gov) - Aug 14, 2017
P4, N=0, Withdrawn, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed | N=190 --> 117 N=52 --> 0 | Terminated --> Withdrawn
- ||| landipirdine (SYN120) / Acorda
Enrollment closed: SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE) (clinicaltrials.gov) - Aug 3, 2017
P2, N=80, Active, not recruiting, Sponsor: Biotie Therapies Inc.
N=52 --> 0 | Terminated --> Withdrawn Recruiting --> Active, not recruiting
- | Trial completion: Brain-Computer Interface System for Training Memory and Attention in Elderly (clinicaltrials.gov) - Aug 2, 2017
P2, N=240, Completed, Sponsor: Duke-NUS Graduate Medical School
Recruiting --> Active, not recruiting Recruiting --> Completed
- | Phase classification, Combination therapy: Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Jul 28, 2017
P2/3, N=330, Completed, Sponsor: Charite University, Berlin, Germany
Recruiting --> Completed Phase classification: P4 --> P2/3
- | simvastatin / Generic mfg.
Biomarker, Phase classification: SimBio: Effects of Simvastatin on Biomarkers (clinicaltrials.gov) - Jul 28, 2017
P4, N=49, Completed, Sponsor: University of Washington
Phase classification: P4 --> P2/3 Phase classification: P=N/A --> P4
- ||| osoresnontrine (BI 409306) / Boehringer Ingelheim
Enrollment closed: BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease. (clinicaltrials.gov) - Jul 26, 2017
P2, N=295, Active, not recruiting, Sponsor: Boehringer Ingelheim
Phase classification: P=N/A --> P4 Recruiting --> Active, not recruiting
- ||| osoresnontrine (BI 409306) / Boehringer Ingelheim
Enrollment closed: Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo (clinicaltrials.gov) - Jul 26, 2017
P2, N=105, Active, not recruiting, Sponsor: Boehringer Ingelheim
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- GSK2647544 / GSK
Trial primary completion date: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single, Oral Escalating Doses of GSK2647544 in Healthy Volunteers (clinicaltrials.gov) - Jul 26, 2017
P1, N=27, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting Trial primary completion date: Feb 2013 --> May 2013
- ||| Rexulti (brexpiprazole) / Lundbeck, Otsuka
Trial completion: Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo (clinicaltrials.gov) - Jul 26, 2017
P=N/A, N=450, Completed, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Trial primary completion date: Feb 2013 --> May 2013 Enrolling by invitation --> Completed
- ||||||| idalopirdine (Lu AE58054) / Otsuka, Eli Lilly, Denovo
Trial completion: STAR Extension: Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease (clinicaltrials.gov) - Jul 26, 2017
P3, N=1463, Completed, Sponsor: H. Lundbeck A/S
Enrolling by invitation --> Completed Active, not recruiting --> Completed
- | Trial completion, Surgery: DeprPOCD: Study of Depressive Symptoms Predicting Postoperative Cognitive Dysfunction (clinicaltrials.gov) - Jul 23, 2017
P=N/A, N=300, Completed, Sponsor: Universit
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion, Trial primary completion date: Imaging the Neural Network Connectivity on Patients With Mild Cognitive Impairment (clinicaltrials.gov) - Jul 21, 2017
P=N/A, N=108, Completed, Sponsor: Chang Gung Memorial Hospital
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Aug 2016 --> Dec 2016
- | Trial completion: Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease (clinicaltrials.gov) - Jul 20, 2017
P1/2, N=39, Completed, Sponsor: Oregon Health and Science University
Recruiting --> Completed | Trial primary completion date: Aug 2016 --> Dec 2016 No longer recruiting --> Completed
- | Trial primary completion date: Exercise Effects in Huntington's Disease (clinicaltrials.gov) - Jul 19, 2017
P=N/A, N=40, Recruiting, Sponsor: University of Zurich
No longer recruiting --> Completed Trial primary completion date: Jun 2017 --> Jan 2018
- |||| Nuplazid (pimavanserin) / Acadia Pharma
Trial completion: A Study of the Safety and Efficacy of Pimavanserin in Patients With Alzheimer's Disease Psychosis (clinicaltrials.gov) - Jul 18, 2017
P2, N=181, Completed, Sponsor: ACADIA Pharmaceuticals Inc.
Trial primary completion date: Jun 2017 --> Jan 2018 Active, not recruiting --> Completed
- | Trial completion: Mental Health and Cognitive Dysfunction: A Multicenter Study at Pediatric Rehabilitation Clinics in North Norway (clinicaltrials.gov) - Jul 17, 2017
P=N/A, N=365, Completed, Sponsor: University Hospital of North Norway
Active, not recruiting --> Completed Recruiting --> Completed
- | Chantix (varenicline) / Pfizer
Trial primary completion date: Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment (clinicaltrials.gov) - Jul 7, 2017
P1, N=0, Withdrawn, Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting --> Completed Trial primary completion date: Mar 2014 --> Nov 2014
- | Trial completion, Phase classification, Trial primary completion date: Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients (clinicaltrials.gov) - Jul 2, 2017
P=N/A, N=22, Completed, Sponsor: Beth Israel Deaconess Medical Center
Trial primary completion date: Mar 2014 --> Nov 2014 Active, not recruiting --> Completed | Phase classification: P2 --> PN/A | Trial primary completion date: Oct 2014 --> May 2015
- | Trial completion: Double Blind Trial of DC Polarization in FTD (clinicaltrials.gov) - Jun 30, 2017
P2, N=20, Completed, Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting --> Completed | Phase classification: P2 --> PN/A | Trial primary completion date: Oct 2014 --> May 2015 Recruiting --> Completed
- | Trial completion: Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=450, Completed, Sponsor: National Institute of Mental Health (NIMH)
Recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion Bodies (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=100, Completed, Sponsor: National Human Genome Research Institute (NHGRI)
Active, not recruiting --> Completed Suspended --> Completed
- | Trial completion: Genetic Studies of Tone Deafness (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=968, Completed, Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)
Suspended --> Completed Recruiting --> Completed
- | Trial completion: The Evaluation and Follow-up of Individuals With Memory Disorder (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=750, Completed, Sponsor: National Institute of Mental Health (NIMH)
Recruiting --> Completed No longer recruiting --> Completed
- | Trial completion: Treatment Study of Frontotemporal Dementia (clinicaltrials.gov) - Jun 30, 2017
P=N/A, N=20, Completed, Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion, Immunomodulating: Effects of an Anti-Inflammatory Drug in Alzheimer's Disease (clinicaltrials.gov) - Jun 30, 2017
P1, N=60, Completed, Sponsor: National Institute of Mental Health (NIMH)
Active, not recruiting --> Completed No longer recruiting --> Completed
- ||| Trial completion, Trial primary completion date, Patient reported outcomes: CIAS PRO: Schizophrenia Cognition Scale Development (clinicaltrials.gov) - Jun 21, 2017
P=N/A, N=102, Completed, Sponsor: New England Research Institutes
No longer recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> Jul 2016
- | citalopram / Generic mfg., perphenazine / Generic mfg.
Trial completion: SPAD: Serotonergic Pharmacotherapy for Agitation of Dementia (clinicaltrials.gov) - Jun 15, 2017
P3, N=0, Completed, Sponsor: Bruce Pollock
Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> Jul 2016 No longer recruiting --> Completed
- || ladostigil hemitartrate (TV-3326) / Avraham
Trial primary completion date: A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment (clinicaltrials.gov) - Jun 15, 2017
P2, N=210, Completed, Sponsor: Avraham Pharmaceuticals Ltd
No longer recruiting --> Completed Trial primary completion date: Dec 2015 --> Jul 2016
- | Trial termination: Use of Transdermal Clonidine in Trauma Patients (clinicaltrials.gov) - Jun 14, 2017
P4, N=22, Terminated, Sponsor: Memorial Health University Medical Center
Trial primary completion date: Dec 2015 --> Jul 2016 Completed --> Terminated; Difficulty in enrolling participants
- |||| Trial completion, Trial primary completion date: Clinical Evaluation of Florbetapir F 18 (18F-AV-45) (clinicaltrials.gov) - Jun 12, 2017
P2, N=1772, Completed, Sponsor: Avid Radiopharmaceuticals
Completed --> Terminated; Difficulty in enrolling participants Recruiting --> Completed | Trial primary completion date: Dec 2017 --> May 2017
- | ketamine / Generic mfg.
Enrollment closed, Trial primary completion date: PODCAST: The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial (clinicaltrials.gov) - Jun 2, 2017
P3, N=600, Active, not recruiting, Sponsor: Washington University School of Medicine
Recruiting --> Completed | Trial primary completion date: Dec 2017 --> May 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2017 --> Jun 2016
- ||| KHK6640 / Kyowa Kirin
Trial completion: A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Jun 1, 2017
P1, N=57, Completed, Sponsor: Kyowa Hakko Kirin Pharma, Inc.
Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2017 --> Jun 2016 Active, not recruiting --> Completed
- | Trial completion, Surgery: Role of Cerebral Oximetry In Reducing Delirium After Complex Cardiac Surgery (clinicaltrials.gov) - Jun 1, 2017
P=N/A, N=250, Completed, Sponsor: University Health Network, Toronto
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Trial primary completion date: Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs) (clinicaltrials.gov) - May 31, 2017
P=N/A, N=510, Active, not recruiting, Sponsor: University of Washington
Active, not recruiting --> Completed Trial primary completion date: Feb 2017 --> Jun 2017
- | Enrollment closed: Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation (clinicaltrials.gov) - May 31, 2017
P1, N=40, Active, not recruiting, Sponsor: VA Office of Research and Development
Trial primary completion date: Feb 2017 --> Jun 2017 Recruiting --> Active, not recruiting
- | Enrollment change, Trial termination: CONFUCIUS: Impact of a Multifaceted Program to Prevent Postoperative Delirium in the Elderly (clinicaltrials.gov) - May 30, 2017
P=N/A, N=175, Terminated, Sponsor: Hospices Civils de Lyon
Recruiting --> Active, not recruiting N=360 --> 175 | Recruiting --> Terminated; enrollment of patients insufficient
- ||| Trial completion, Enrollment change: PACR-AD: Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease (clinicaltrials.gov) - May 22, 2017
P=N/A, N=66, Completed, Sponsor: Posit Science Corporation
N=360 --> 175 | Recruiting --> Terminated; enrollment of patients insufficient Recruiting --> Completed | N=40 --> 66
- | Enrollment closed, Trial primary completion date, HEOR: Behavioral Interventions to Prevent or Delay Dementia (clinicaltrials.gov) - May 19, 2017
P=N/A, N=600, Active, not recruiting, Sponsor: Mayo Clinic
Recruiting --> Completed | N=40 --> 66 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2017 --> Mar 2018
- | Trial completion: SHARED DECISION MAKING IN LONG-TERM CARE FACILITIES (clinicaltrials.gov) - May 19, 2017
P=N/A, N=40, Completed, Sponsor: Radboud University
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2017 --> Mar 2018 Enrolling by invitation --> Completed
- |||| edonerpic (T-817MA) / Fujifilm Holdings
Trial completion: Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease (US202) (clinicaltrials.gov) - May 17, 2017
P2, N=484, Completed, Sponsor: Toyama Chemical Co., Ltd.
Enrolling by invitation --> Completed Active, not recruiting --> Completed
- | Trial primary completion date: CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease (clinicaltrials.gov) - May 16, 2017
P=N/A, N=80, Enrolling by invitation, Sponsor: Washington University School of Medicine
Active, not recruiting --> Completed Trial primary completion date: Feb 2017 --> Jul 2017
- || GSK2981710 / GSK
Enrollment change: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects (clinicaltrials.gov) - May 9, 2017
P1, N=116, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Feb 2017 --> Jul 2017 N=96 --> 116