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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- Enrollment change: Research Study on Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) (clinicaltrials.gov) - Jan 17, 2013
P=N/A, N=100, Completed, Sponsor: New York University School of Medicine
N=200 --> 100
- Trial completion: Research Study on Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) (clinicaltrials.gov) - Jan 17, 2013
P=N/A, N=100, Completed, Sponsor: New York University School of Medicine
N=200 --> 100 Active, not recruiting --> Completed
- Enrollment change: AVEC: The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial (clinicaltrials.gov) - Jan 13, 2013
P2, N=53, Completed, Sponsor: University of Southern California
Active, not recruiting --> Completed N=100 --> 53
- Trial completion: AVEC: The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial (clinicaltrials.gov) - Jan 13, 2013
P2, N=53, Completed, Sponsor: University of Southern California
N=100 --> 53 Active, not recruiting --> Completed
- P1 data, Trial initiation date: DEMENSTIM: Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies (clinicaltrials.gov) - Jan 10, 2013
P1, N=6, Recruiting, Sponsor: University Hospital, Rouen
Active, not recruiting --> Completed Initiation date: May 2012 --> Oct 2012
- Enrollment change: Cognitive Impairment in Parkinson's Disease Categorised in Accordance to Motor Symptoms (clinicaltrials.gov) - Jan 10, 2013
P=N/A, N=107, Completed, Sponsor: University of Aarhus
Initiation date: May 2012 --> Oct 2012 N=80 --> 107
- Enrollment open, P1 data: DEMENSTIM: Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies (clinicaltrials.gov) - Jan 10, 2013
P1, N=6, Recruiting, Sponsor: University Hospital, Rouen
N=80 --> 107 Not yet recruiting --> Recruiting
- ||| Nine Phase One (mannote sodium) / Shanghai Greenvalley
Enrollment closed: Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Jan 10, 2013
P2, N=252, Active, not recruiting, Sponsor: Shanghai Greenvalley Pharmaceutical Co., Ltd.
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion: Early Occupational Therapy for Delirium Prevention in Older Patients Admitted to Critical Care Unit (clinicaltrials.gov) - Jan 10, 2013
P=N/A, N=126, Completed, Sponsor: University of Chile
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion: Cognitive Impairment in Parkinson's Disease Categorised in Accordance to Motor Symptoms (clinicaltrials.gov) - Jan 10, 2013
P=N/A, N=107, Completed, Sponsor: University of Aarhus
Recruiting --> Completed Not yet recruiting --> Completed
- |||||| LMTX (hydromethylthionine) / TauRx
Enrollment open: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Jan 10, 2013
P3, N=833, Recruiting, Sponsor: TauRx Therapeutics Ltd
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- ||| rivastigmine transdermal / Generic mfg., rivastigmine / Generic mfg.
Trial initiation date: Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia (clinicaltrials.gov) - Jan 9, 2013
P4, N=127, Recruiting, Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Recruiting Initiation date: Apr 2012 --> Aug 2012
- |||| rivastigmine transdermal / Generic mfg., rivastigmine / Generic mfg.
Enrollment open: Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia (clinicaltrials.gov) - Jan 9, 2013
P4, N=127, Recruiting, Sponsor: Novartis Pharmaceuticals
Initiation date: Apr 2012 --> Aug 2012 Not yet recruiting --> Recruiting
- Enrollment change: Pre-CREST-X: Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study (clinicaltrials.gov) - Jan 8, 2013
P2, N=38, Completed, Sponsor: Massachusetts General Hospital
Not yet recruiting --> Recruiting N=60 --> 38
- |||| PF-05212377 / Pfizer
Enrollment open: Study Evaluating TheSafety And Efficacy Of PF-05212377 Or Placebo In Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms On Donepezil (clinicaltrials.gov) - Jan 8, 2013
P2, N=342, Recruiting, Sponsor: Pfizer
N=60 --> 38 Not yet recruiting --> Recruiting
- Trial completion: Pre-CREST-X: Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study (clinicaltrials.gov) - Jan 8, 2013
P2, N=38, Completed, Sponsor: Massachusetts General Hospital
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||||| encenicline (EVP-6124) / Forum Pharmaceuticals, Mitsubishi Tanabe
New P2 trial: Safety and Efficacy of MT-4666 (clinicaltrials.gov) - Jan 7, 2013
P2, N=450, Recruiting, Sponsor: Mitsubishi Tanabe Pharma Corporation
- Enrollment open: Volunteers Adding Life in Dementia: VALID (clinicaltrials.gov) - Jan 7, 2013
P=N/A, N=120, Recruiting, Sponsor: Queen's University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- |||| rivastigmine transdermal / Generic mfg.
Trial completion: Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44 (clinicaltrials.gov) - Jan 7, 2013
P4, N=716, Completed, Sponsor: Novartis
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
Metastases: Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients (clinicaltrials.gov) - Jan 7, 2013
P2, N=20, Recruiting, Sponsor: Fraser Health
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ||||| New P2 trial: Efficacy and Safety of Fufangdanshen Tablets in Mild to Moderate Vascular Dementia (clinicaltrials.gov) - Jan 2, 2013
P2, N=240, Recruiting, Sponsor: Dongzhimen Hospital, Beijing
- sevoflurane / Generic mfg., midazolam hydrochloride / Generic mfg.
Enrollment change, Surgery: A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=90, Completed, Sponsor: Korea University Anam Hospital
Not yet recruiting --> Recruiting N=120 --> 90
- Enrollment change: Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=200, Active, not recruiting, Sponsor: University of Nebraska
N=120 --> 90 N=350 --> 200
- miglustat / Generic mfg.
New P3 trial: Application of Miglustat in Patients With Niemann-Pick Type C (clinicaltrials.gov) - Jan 2, 2013
P3, N=5, Completed, Sponsor: National Taiwan University Hospital
- Enrollment closed: Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=200, Active, not recruiting, Sponsor: University of Nebraska
N=350 --> 200 Recruiting --> Active, not recruiting
- sevoflurane / Generic mfg., midazolam hydrochloride / Generic mfg.
Trial completion, Surgery: A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=90, Completed, Sponsor: Korea University Anam Hospital
Recruiting --> Active, not recruiting Recruiting --> Completed
- ||||| donepezil sustained release / Generic mfg.
Enrollment change: Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease (clinicaltrials.gov) - Jan 1, 2013
P3, N=1467, Completed, Sponsor: Eisai Inc.
Recruiting --> Completed N=1200 --> 1467
- | donepezil sustained release / Generic mfg., donepezil / Generic mfg.
Trial completion: A Study Versus E2020 10mg Followed by an Open-label Extension Phase to Explore the Safety of E2020 SR 23 mg in Japanese Subjects With Severe Alzheimer's Type Dementia (clinicaltrials.gov) - Dec 26, 2012
P2, N=40, Completed, Sponsor: Eisai Co., Ltd.
N=1200 --> 1467 Active, not recruiting --> Completed
- | Enrollment change: APA-AD: Bupropion for the Treatment of Apathy in Alzheimer's Dementia (clinicaltrials.gov) - Dec 19, 2012
P3, N=216, Recruiting, Sponsor: University Hospital, Bonn
Active, not recruiting --> Completed N=270 --> 216
- | Enrollment change: Memantine and Cognitive Dysfunction in Bipolar Disorder (clinicaltrials.gov) - Dec 17, 2012
P4, N=40, Completed, Sponsor: Massachusetts General Hospital
N=270 --> 216 N=75 --> 40
- | Trial completion: Memantine and Cognitive Dysfunction in Bipolar Disorder (clinicaltrials.gov) - Dec 17, 2012
P4, N=40, Completed, Sponsor: Massachusetts General Hospital
N=75 --> 40 Recruiting --> Completed
- Enrollment open: EPAC-M: Physical Training and Cognitive Activity on the Mild Cognitive Impairment (MCI) Patient (clinicaltrials.gov) - Dec 16, 2012
P=N/A, N=36, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting --> Completed Not yet recruiting --> Recruiting
- Levemir (insulin detemir rDNA origin) / Novo Nordisk
Trial completion: Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days (clinicaltrials.gov) - Dec 16, 2012
P2, N=60, Completed, Sponsor: University of Washington
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial completion, Video: Ecological Assessment of Apathy in Alzheimer's Disease and in Control Subjects: Video Recognition and Actigraphy (clinicaltrials.gov) - Dec 16, 2012
P=N/A, N=82, Completed, Sponsor: Centre Hospitalier Universitaire de Nice
Recruiting --> Completed Not yet recruiting --> Completed
- modafinil / Generic mfg.
Enrollment change: Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia (clinicaltrials.gov) - Dec 12, 2012
P4, N=38, Completed, Sponsor: University of California, Davis
Not yet recruiting --> Completed N=80 --> 38
- paracetamol / Generic mfg., dronabinol oral / Generic mfg.
Enrollment open: Delta-THC in Dementia (clinicaltrials.gov) - Dec 12, 2012
P2, N=150, Recruiting, Sponsor: Radboud University
N=80 --> 38 Not yet recruiting --> Recruiting
- Trial completion: Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes (clinicaltrials.gov) - Dec 12, 2012
P1/2, N=18, Completed, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- modafinil / Generic mfg.
Trial completion: Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia (clinicaltrials.gov) - Dec 12, 2012
P4, N=38, Completed, Sponsor: University of California, Davis
Active, not recruiting --> Completed Recruiting --> Completed
- Trial initiation date: LYLO: " The Eyes Have it " : Ocular Saccade Abnormalities in Prodromal Alzheimer's Disease (clinicaltrials.gov) - Dec 11, 2012
P=N/A, N=90, Recruiting, Sponsor: University Hospital, Bordeaux
Recruiting --> Completed Initiation date: Sep 2012 --> Dec 2012
- Enrollment open: LYLO: " The Eyes Have it " : Ocular Saccade Abnormalities in Prodromal Alzheimer's Disease (clinicaltrials.gov) - Dec 11, 2012
P=N/A, N=90, Recruiting, Sponsor: University Hospital, Bordeaux
Initiation date: Sep 2012 --> Dec 2012 Not yet recruiting --> Recruiting
- Clinical: Therapeutic Effect of Direct Current Stimulation on Cognitive Function of Mild to Moderate Alzheimer Patients (clinicaltrials.gov) - Dec 9, 2012
P=N/A, N=33, Completed, Sponsor: Assiut University
- |||||| LMTX (hydromethylthionine) / TauRx
Enrollment open: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease (clinicaltrials.gov) - Dec 9, 2012
P3, N=700, Recruiting, Sponsor: TauRx Therapeutics Ltd
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Chantix (varenicline) / Pfizer
Trial withdrawal: Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment (clinicaltrials.gov) - Dec 7, 2012
P1, N=0, Withdrawn, Sponsor: National Institute on Drug Abuse (NIDA)
Not yet recruiting --> Recruiting Not yet recruiting --> Withdrawn
- Chantix (varenicline) / Pfizer
Enrollment change: Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment (clinicaltrials.gov) - Dec 7, 2012
P1, N=0, Withdrawn, Sponsor: National Institute on Drug Abuse (NIDA)
Not yet recruiting --> Withdrawn N=40 --> 0
- ||| Biomarker: Effect of Cerefolin®/CerefolinNAC® on Biomarker Measurements (clinicaltrials.gov) - Dec 6, 2012
P=N/A, N=119, Enrolling by invitation, Sponsor: Pamlab, Inc.
- Enrollment change: An Open Positron Emission Tomography Study to Assess the Effects of Varying Mass of AZD4694 on Radioligand Binding Parameters in Healthy Volunteers and Patients With Alzheimer's Disease (clinicaltrials.gov) - Dec 6, 2012
P1, N=16, Completed, Sponsor: AstraZeneca
N=40 --> 0 N=24 --> 16
- | Trial completion: An Open Positron Emission Tomography Study to Assess the Effects of Varying Mass of AZD4694 on Radioligand Binding Parameters in Healthy Volunteers and Patients With Alzheimer's Disease (clinicaltrials.gov) - Dec 6, 2012
P1, N=16, Completed, Sponsor: AstraZeneca
N=24 --> 16 Recruiting --> Completed
- donepezil / Generic mfg.
Trial withdrawal: Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease (clinicaltrials.gov) - Dec 5, 2012
P4, N=0, Withdrawn, Sponsor: Eisai Inc.
Recruiting --> Completed Terminated --> Withdrawn
- donepezil / Generic mfg.
Enrollment change: Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease (clinicaltrials.gov) - Dec 5, 2012
P4, N=0, Withdrawn, Sponsor: Eisai Inc.
Terminated --> Withdrawn N=200 --> 0
- Pegasys (pegylated interferon α -2a) / Roche
Trial completion: Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS) (clinicaltrials.gov) - Dec 5, 2012
P=N/A, N=100, Completed, Sponsor: Aarhus University Hospital
N=200 --> 0 Recruiting --> Completed