Delirium, Dementia, Amnestic, Cognitive Disorders
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 122 Companies   196 Products   196 Products   116 Mechanisms of Action   3 Trials   2338 News 


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  • ||||||||||  Trial completion, Trial initiation date, Trial primary completion date:  Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment (clinicaltrials.gov) -  Jan 18, 2018   
    P3,  N=200, Completed, 
    Active, not recruiting --> Completed | Initiation date: Sep 2010 --> Jun 2011 | Trial primary completion date: Dec 2017 --> Dec 2016
  • ||||||||||  Enrollment change, Trial termination, Trial primary completion date:  2-StaLi: Cognitive Outcome After Two-stage Liver-Operation (clinicaltrials.gov) -  Jan 17, 2018   
    P=N/A,  N=23, Terminated, 
    Active, not recruiting --> Completed | Initiation date: Sep 2010 --> Jun 2011 | Trial primary completion date: Dec 2017 --> Dec 2016 N=40 --> 23 | Recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Apr 2017
  • ||||||||||  donanemab (LY3002813) / Eli Lilly
    Trial completion, Trial primary completion date:  A Study of LY3002813 in Participants With Alzheimer's Disease (clinicaltrials.gov) -  Dec 26, 2017   
    P1,  N=100, Completed, 
    Trial primary completion date: Dec 2017 --> Dec 2018 Active, not recruiting --> Completed | Trial primary completion date: Nov 2017 --> Aug 2016
  • ||||||||||  atorvastatin / Generic mfg.
    Trial completion, Enrollment change:  Modulation of Monocyte Activation by Atorvastatin in HIV Infection (clinicaltrials.gov) -  Dec 12, 2017   
    P4,  N=5, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | N=15 --> 5
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Trial initiation date, Trial primary completion date, Surgery:  Decreasing the Incidence of Delirium After Cardiac Surgery (clinicaltrials.gov) -  Dec 7, 2017   
    P4,  N=200, Not yet recruiting, 
    Phase classification: P1/2 --> P=N/A | N=54 --> 82 Initiation date: Jan 2016 --> Jan 2018 | Trial primary completion date: Dec 2017 --> Dec 2018
  • ||||||||||  Enrollment change, Trial termination, Trial primary completion date:  LESCOD: "Lewy Body Screening in Cognitive Disorders" (clinicaltrials.gov) -  Dec 7, 2017   
    P=N/A,  N=133, Terminated, 
    Initiation date: Jan 2016 --> Jan 2018 | Trial primary completion date: Dec 2017 --> Dec 2018 N=180 --> 133 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Aug 2017; recruitment problems
  • ||||||||||  Trial completion, Enrollment change:  CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's Disease (clinicaltrials.gov) -  Nov 30, 2017   
    P=N/A,  N=58, Completed, 
    Phase classification: P1/2 --> P=N/A | N=18 --> 5 Enrolling by invitation --> Completed | N=80 --> 58
  • ||||||||||  Trial primary completion date:  18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) -  Nov 30, 2017   
    P1,  N=10, Active, not recruiting, 
    Enrolling by invitation --> Completed | N=80 --> 58 Trial primary completion date: Oct 2017 --> Mar 2018
  • ||||||||||  Trial completion, Enrollment change:  Retaining Cognition While Avoiding Late-Life Depression (clinicaltrials.gov) -  Nov 14, 2017   
    P=N/A,  N=94, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | N=136 --> 94
  • ||||||||||  Trial completion:  Effectiveness of a Multifactorial Intervention on Frailty (clinicaltrials.gov) -  Nov 13, 2017   
    P=N/A,  N=352, Completed, 
    Active, not recruiting --> Completed | N=136 --> 94 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Enrollment change, Trial primary completion date:  Retinal Neurodegenerative Signs in Alzheimer's Diseases (clinicaltrials.gov) -  Nov 13, 2017   
    P=N/A,  N=200, Completed, 
    Active, not recruiting --> Completed Recruiting --> Completed | N=300 --> 200 | Trial primary completion date: Jun 2015 --> Jun 2014
  • ||||||||||  Trial completion:  Cataract Removal and Alzheimer's Disease (clinicaltrials.gov) -  Nov 9, 2017   
    P=N/A,  N=122, Completed, 
    Recruiting --> Completed | N=300 --> 200 | Trial primary completion date: Jun 2015 --> Jun 2014 Active, not recruiting --> Completed
  • ||||||||||  osoresnontrine (BI 409306) / Boehringer Ingelheim
    Trial completion, Enrollment change:  Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo (clinicaltrials.gov) -  Nov 8, 2017   
    P2,  N=128, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | N=105 --> 128
  • ||||||||||  Trial completion, Trial primary completion date, IO biomarker:  IMABio3: Central and Systemic Inflammation in Alzheimer's Disease (clinicaltrials.gov) -  Nov 6, 2017   
    P=N/A,  N=125, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Apr 2017
  • ||||||||||  Trial completion, Enrollment change:  Imaging of Cognition, Learning, and Memory in Aging (clinicaltrials.gov) -  Nov 1, 2017   
    P=N/A,  N=294, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Apr 2017 Recruiting --> Completed | N=550 --> 294
  • ||||||||||  Phase classification, HEOR:  Molecular Cerebral Imaging in Incipient Dementia (MCI-ID) II (clinicaltrials.gov) -  Oct 31, 2017   
    P3,  N=1500, Not yet recruiting, 
    Recruiting --> Completed | N=550 --> 294 Phase classification: P=N/A --> P3
  • ||||||||||  fluoxetine / Generic mfg.
    Phase classification:  Fluoxetine Prevention Trial (clinicaltrials.gov) -  Oct 31, 2017   
    P1,  N=376, Not yet recruiting, 
    Phase classification: P=N/A --> P3 Phase classification: P=N/A --> P1
  • ||||||||||  aripiprazole / Generic mfg.
    Enrollment change, Trial termination, Trial primary completion date:  Aripiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type (clinicaltrials.gov) -  Oct 16, 2017   
    P3,  N=150, Terminated, 
    Phase classification: P4 --> P=N/A | N=15 --> 11 N=880 --> 150 | Recruiting --> Terminated | Trial primary completion date: Jul 2017 --> Mar 2016; It was difficult to secure enrollment of the targeted number of subjects.
  • ||||||||||  Enrollment closed:  18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) -  Oct 13, 2017   
    P1,  N=10, Active, not recruiting, 
    N=880 --> 150 | Recruiting --> Terminated | Trial primary completion date: Jul 2017 --> Mar 2016; It was difficult to secure enrollment of the targeted number of subjects. Recruiting --> Active, not recruiting
  • ||||||||||  Trial completion, Trial primary completion date:  MIG-HD: Multicentric Intracerebral Grafting in Huntington's Disease (clinicaltrials.gov) -  Oct 9, 2017   
    P2,  N=54, Completed, 
    Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2013 --> Dec 2013
  • ||||||||||  Enrollment change:  Memantine and Cognitive Dysfunction in Bipolar Disorder (clinicaltrials.gov) -  Oct 7, 2017   
    P4,  N=72, Completed, 
    Recruiting --> Completed | Trial primary completion date: May 2013 --> Dec 2013 N=40 --> 72
  • ||||||||||  donanemab (LY3002813) / Eli Lilly
    Trial primary completion date:  A Study of LY3002813 in Participants With Alzheimer's Disease (clinicaltrials.gov) -  Sep 25, 2017   
    P1,  N=100, Active, not recruiting, 
    Recruiting --> Completed | N=80 --> 45 Trial primary completion date: Aug 2017 --> Nov 2017
  • ||||||||||  Trial primary completion date, IO biomarker:  IMABio3: Central and Systemic Inflammation in Alzheimer's Disease (clinicaltrials.gov) -  Sep 20, 2017   
    P=N/A,  N=125, Active, not recruiting, 
    Trial primary completion date: Aug 2017 --> Nov 2017 Trial primary completion date: Jun 2017 --> Sep 2017