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121 Companies |
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195 Products |
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195 Products |
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116 Mechanisms of Action |
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3 Trials |
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2334 News |
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- |||| edonerpic (T-817MA) / Fujifilm Holdings
Enrollment open: Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease (US202) (clinicaltrials.gov) - Apr 29, 2014
P2, N=450, Recruiting, Sponsor: Toyama Chemical Co., Ltd.
Not yet recruiting --> Recruiting
- | citalopram / Generic mfg., risperidone / Generic mfg.
Trial completion: Treating Behavioral Disturbances in Individuals With Dementia (clinicaltrials.gov) - Apr 28, 2014
P2, N=137, Completed, Sponsor: University of Pittsburgh
Not yet recruiting --> Recruiting No longer recruiting --> Completed
- |||| LMTX (hydromethylthionine) / TauRx
Trial primary completion date: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 27, 2014
P3, N=833, Recruiting, Sponsor: TauRx Therapeutics Ltd
No longer recruiting --> Completed Trial primary completion date: Jul 2015 --> Sep 2015
- ||| LMTX (hydromethylthionine) / TauRx
Trial completion date: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 27, 2014
P3, N=833, Recruiting, Sponsor: TauRx Therapeutics Ltd
Trial primary completion date: Jul 2015 --> Sep 2015 Trial completion date: Aug 2015 --> Oct 2015
- SAR228810 / Sanofi
Enrollment closed: Single and Repeated Dosing Study to Assess the Safety and the Concentration-time Profile of SAR228810 in Alzheimer's Patients (clinicaltrials.gov) - Apr 27, 2014
P1, N=48, Active, not recruiting, Sponsor: Sanofi
Trial completion date: Aug 2015 --> Oct 2015 Recruiting --> Active, not recruiting
- Trial completion: ThinkingFit: Combined Physical, Cognitive and Social Treatment in Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Apr 24, 2014
P=N/A, N=128, Completed, Sponsor: Dr Thomas Dannhauser
Recruiting --> Active, not recruiting Recruiting --> Completed
- Zolinza (vorinostat) / Merck (MSD)
New P1/2 trial: Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1 (clinicaltrials.gov) - Apr 24, 2014
P1/2, N=15, Recruiting, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Byetta (exenatide) / AstraZeneca
Enrollment change: A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease (clinicaltrials.gov) - Apr 23, 2014
P2, N=100, Recruiting, Sponsor: National Institute on Aging (NIA)
Recruiting --> Completed N=230 --> 100
- ||| KHK6640 / Kyowa Kirin
New P1 trial: A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 23, 2014
P1, N=62, Not yet recruiting, Sponsor: Kyowa Hakko Kirin Pharma, Inc.
- Trial completion: Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses (clinicaltrials.gov) - Apr 22, 2014
P2, N=100, Completed, Sponsor: Johns Hopkins University
N=230 --> 100 Recruiting --> Completed
- || Biomarker, Enrollment change: A Biospecimen and Clinical Data Study on Patients for Drug & Biomarker Discovery (clinicaltrials.gov) - Apr 22, 2014
P=N/A, N=600, Recruiting, Sponsor: Sanguine Biosciences
Recruiting --> Completed N=300 --> 600
- Clinical: Brazil Nuts Effects on Selenium Status and Cognitive Performance (clinicaltrials.gov) - Apr 21, 2014
P=N/A, N=31, Completed, Sponsor: University of Sao Paulo
- | Enbrel (etanercept) / Pfizer, Amgen
Trial completion: STEADI-09: Safety and Tolerability of Etanercept in Alzheimer's Disease (clinicaltrials.gov) - Apr 21, 2014
P2, N=41, Completed, Sponsor: University of Southampton
N=300 --> 600 Recruiting --> Completed
- Trial completion: Brazil Nuts Effects on Selenium Status and Cognitive Performance (clinicaltrials.gov) - Apr 21, 2014
P=N/A, N=31, Completed, Sponsor: University of Sao Paulo
Recruiting --> Completed Not yet recruiting --> Completed
- | New P1 trial: Florbetapir Calibration to the Centiloid Scale (clinicaltrials.gov) - Apr 21, 2014
P1, N=35, Recruiting, Sponsor: Avid Radiopharmaceuticals
- Daliresp (roflumilast) / AstraZeneca, Takeda, AbbVie
Enrollment closed, Combination therapy: Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults (clinicaltrials.gov) - Apr 21, 2014
P1, N=28, Active, not recruiting, Sponsor: Takeda
Not yet recruiting --> Completed Recruiting --> Active, not recruiting
- Clinical: Complementary Interventions on Patients With Dementia: Comparative and Longitudinal Research (clinicaltrials.gov) - Apr 20, 2014
P=N/A, N=200, Recruiting, Sponsor: National Cheng-Kung University Hospital
- | midazolam hydrochloride / Generic mfg.
New P4 trial, Surgery: Decreasing the Incidence of Delirium After Cardiac Surgery (clinicaltrials.gov) - Apr 20, 2014
P4, N=200, Recruiting, Sponsor: University of California, Los Angeles
- |||| crenezumab (MABT5102A) / Roche
Biomarker, Trial completion: BLAZE: A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 20, 2014
P2, N=91, Completed, Sponsor: Genentech
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment open: Florbetapir Calibration to the Centiloid Scale (clinicaltrials.gov) - Apr 20, 2014
P1, N=35, Recruiting, Sponsor: Avid Radiopharmaceuticals
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment change: Living With Frontotemporal Dementia (clinicaltrials.gov) - Apr 18, 2014
P=N/A, N=40, Recruiting, Sponsor: National Human Genome Research Institute (NHGRI)
Not yet recruiting --> Recruiting N=60 --> 40
- Trial initiation date: SensiCare: Sensory Support Care for Elderly Patients Suffering From Alzheimer'S-type Neurodegenerative Disease (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=35, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
N=60 --> 40 Initiation date: Nov 2013 --> Jun 2013
- ||| Patient reported outcomes: CIAS PRO: Schizophrenia Cognition Scale Development (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=125, Recruiting, Sponsor: New England Research Institutes
- Clinical: Effects of Exercise Training in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=19, Completed, Sponsor: National Taiwan University Hospital
- Enrollment change: ISALP: Isotopic Imaging for Prodromal Alzheimer's Disease (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=143, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
Initiation date: Nov 2013 --> Jun 2013 N=355 --> 143
- Enrollment closed: ISALP: Isotopic Imaging for Prodromal Alzheimer's Disease (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=143, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
N=355 --> 143 Recruiting --> Active, not recruiting
- Biomarker, Enrollment change: Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=40, Completed, Sponsor: Duke University
Recruiting --> Active, not recruiting N=120 --> 40
- | Biomarker, Trial completion: Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias (clinicaltrials.gov) - Apr 17, 2014
P=N/A, N=40, Completed, Sponsor: Duke University
N=120 --> 40 Recruiting --> Completed
- | Trial completion: Effect of NeuroAD on Alzheimer Patients (clinicaltrials.gov) - Apr 16, 2014
P=N/A, N=32, Completed, Sponsor: Neuronix Ltd
Recruiting --> Completed Recruiting --> Completed
- galantamine hydrobromide / Generic mfg.
Trial initiation date: The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 14, 2014
P4, N=1, Terminated, Sponsor: Janssen-Cilag, S.A.
Recruiting --> Completed Initiation date: Jan 2011 --> May 2011
- || Enrollment change: PRISM Registry: Pseudobulbar Affect Registry Series (clinicaltrials.gov) - Apr 14, 2014
P=N/A, N=5290, Completed, Sponsor: Avanir Pharmaceuticals
Initiation date: Jan 2011 --> May 2011 N=10000 --> 5290
- Enrollment closed: Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI (clinicaltrials.gov) - Apr 14, 2014
P4, N=50, Active, not recruiting, Sponsor: University Hospital, Basel, Switzerland
N=10000 --> 5290 Recruiting --> Active, not recruiting
- ||| Trial completion: PRISM Registry: Pseudobulbar Affect Registry Series (clinicaltrials.gov) - Apr 14, 2014
P=N/A, N=5290, Completed, Sponsor: Avanir Pharmaceuticals
Recruiting --> Active, not recruiting Recruiting --> Completed
- donepezil / Generic mfg., cilostazol / Generic mfg.
Trial primary completion date, Monotherapy: Cilostazol Augmentation Study in Dementia (clinicaltrials.gov) - Apr 13, 2014
P4, N=46, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed Trial primary completion date: Dec 2011 --> Jun 2012
- donepezil / Generic mfg., cilostazol / Generic mfg.
Trial completion, Monotherapy: Cilostazol Augmentation Study in Dementia (clinicaltrials.gov) - Apr 13, 2014
P4, N=46, Completed, Sponsor: Seoul National University Hospital
Trial primary completion date: Dec 2011 --> Jun 2012 Recruiting --> Completed
- clonidine / Generic mfg.
Trial initiation date: LUCID: The Oslo Study of Clonidine in Elderly Patients With Delirium (clinicaltrials.gov) - Apr 13, 2014
P2, N=100, Recruiting, Sponsor: Oslo University Hospital
Recruiting --> Completed Initiation date: Jun 2014 --> Apr 2014
- Trial termination, Surgery: Autonomic Cardiovascular Control for Elderly Surgery Patients (clinicaltrials.gov) - Apr 13, 2014
P=N/A, N=3, Terminated, Sponsor: Oslo University Hospital
Initiation date: Jun 2014 --> Apr 2014 Recruiting --> Terminated; Practical circumstances made it too difficult to carry out as planned.
- Enrollment change, Surgery: Autonomic Cardiovascular Control for Elderly Surgery Patients (clinicaltrials.gov) - Apr 13, 2014
P=N/A, N=3, Terminated, Sponsor: Oslo University Hospital
Recruiting --> Terminated; Practical circumstances made it too difficult to carry out as planned. N=40 --> 3
- clonidine / Generic mfg.
Enrollment open: LUCID: The Oslo Study of Clonidine in Elderly Patients With Delirium (clinicaltrials.gov) - Apr 13, 2014
P2, N=100, Recruiting, Sponsor: Oslo University Hospital
N=40 --> 3 Not yet recruiting --> Recruiting
- Enrollment closed: Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study) (clinicaltrials.gov) - Apr 13, 2014
P2, N=54, Active, not recruiting, Sponsor: Charite University, Berlin, Germany
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Enrollment open: PET Imaging in MCI Following ADT for PCa (clinicaltrials.gov) - Apr 13, 2014
P=N/A, N=12, Recruiting, Sponsor: Imperial College London
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Trial completion: Dose Response Study of Aerobic Exercise in Older Adults (clinicaltrials.gov) - Apr 13, 2014
P0, N=101, Completed, Sponsor: Jeff Burns, MD
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Clinical: CBAT: The Effectiveness of Computerized Auditory Training Programme on Children With Auditory Processing Disorder (clinicaltrials.gov) - Apr 9, 2014
P=N/A, N=39, Completed, Sponsor: National University Health System, Singapore
- | dexmedetomidine / Generic mfg.
Clinical: DexPeds: Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children (clinicaltrials.gov) - Apr 8, 2014
P3, N=128, Completed, Sponsor: St. Luke's-Roosevelt Hospital Center
Active, not recruiting --> Completed Recruiting --> Completed
- Enrollment closed: Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls (clinicaltrials.gov) - Apr 8, 2014
P1, N=32, Active, not recruiting, Sponsor: Institute for Neurodegenerative Disorders
Recruiting --> Completed Recruiting --> Active, not recruiting
- || lanabecestat (AZD3293) / AstraZeneca, Eli Lilly
Enrollment closed: AZD3293TQT: AZD3293 Thorough QT Study in Healthy Male Volunteers (clinicaltrials.gov) - Apr 7, 2014
P1, N=52, Active, not recruiting, Sponsor: AstraZeneca
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- ||||| New P4 trial: The Feasibility of Florbetapir Quantitation in Europe (clinicaltrials.gov) - Apr 6, 2014
P4, N=96, Recruiting, Sponsor: Avid Radiopharmaceuticals
- |||| Enrollment open: The Feasibility of Florbetapir Quantitation in Europe (clinicaltrials.gov) - Apr 6, 2014
P4, N=96, Recruiting, Sponsor: Avid Radiopharmaceuticals
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Trial completion: Yogic Breathing Changes Salivary Components (clinicaltrials.gov) - Apr 6, 2014
P=N/A, N=20, Completed, Sponsor: Medical University of South Carolina
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- ||| Cerebrolysin (porcine brain-derived proteolytic peptide fraction) / Novartis, EVER Pharma
Trial initiation date: Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT) (clinicaltrials.gov) - Apr 2, 2014
P4, N=510, Not yet recruiting, Sponsor: Ever Neuro Pharma GmbH
Not yet recruiting --> Completed Initiation date: Sep 2013 --> Jul 2014