|
121 Companies |
|
195 Products |
|
195 Products |
|
116 Mechanisms of Action |
|
3 Trials |
|
2334 News |
|
| «12...1415161718192021222324...4647» |
- | amphetamine/dextroamphetamine ER / Generic mfg.
Trial completion, Trial primary completion date: Adderall XR and Processing Speed in Multiple Sclerosis (MS) (clinicaltrials.gov) - Feb 19, 2015
P2/3, N=70, Completed, Sponsor: London Health Sciences Centre
Not yet recruiting --> Completed | Trial primary completion date: Sep 2013 --> Feb 2013
- Trial completion: Use of Alternative Medicine in Patients With Dementia and Mild Cognitive Dysfunction (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=151, Completed, Sponsor: University Hospital of North Norway
Not yet recruiting --> Completed | Trial primary completion date: Sep 2013 --> Feb 2013 Recruiting --> Completed
- ||| Biomarker, Trial completion, Enrollment change: A Non-drug Methods Study in Participants With Alzheimer's Disease (clinicaltrials.gov) - Feb 19, 2015
P1, N=57, Completed, Sponsor: Eli Lilly and Company
Recruiting --> Completed Active, not recruiting --> Completed | N=196 --> 57
- idalopirdine (Lu AE58054) / Otsuka, Eli Lilly, Denovo
Enrollment open: Pharmacokinetic Properties of Idalopirdine (Lu AE58054) in Subjects With and Without Impaired Kidney Function (clinicaltrials.gov) - Feb 15, 2015
P1, N=32, Recruiting, Sponsor: H. Lundbeck A/S
Active, not recruiting --> Completed | N=196 --> 57 Not yet recruiting --> Recruiting
- |||| osoresnontrine (BI 409306) / Boehringer Ingelheim
Enrollment open: BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease. (clinicaltrials.gov) - Feb 13, 2015
P2, N=336, Recruiting, Sponsor: Boehringer Ingelheim
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||| rivastigmine transdermal / Generic mfg., rivastigmine / Generic mfg.
Enrollment closed: Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia (clinicaltrials.gov) - Feb 13, 2015
P4, N=113, Active, not recruiting, Sponsor: Novartis Pharmaceuticals
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- || Trial primary completion date: Measuring the Impact of Cognitive and Psychosocial Interventions in Persons With Mild Cognitive Impairment (clinicaltrials.gov) - Feb 12, 2015
P=N/A, N=162, Recruiting, Sponsor: Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Recruiting --> Active, not recruiting Trial primary completion date: Mar 2015 --> Dec 2015
- TTP4000 / vTv Therapeutics
Trial completion, Enrollment change, Trial primary completion date: A Safety Study of TTP4000 in Subjects With Alzheimer's Disease (clinicaltrials.gov) - Feb 12, 2015
P1, N=8, Completed, Sponsor: TransTech Pharma
Trial primary completion date: Mar 2015 --> Dec 2015 Active, not recruiting --> Completed | N=16 --> 8 | Trial primary completion date: Sep 2012 --> Feb 2013
- venlafaxine / Generic mfg.
Trial primary completion date: Venlafaxine for Depression in Alzheimer's Disease (DIADs-3) (clinicaltrials.gov) - Feb 11, 2015
P=N/A, N=50, Recruiting, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed | N=16 --> 8 | Trial primary completion date: Sep 2012 --> Feb 2013 Trial primary completion date: Dec 2013 --> Dec 2015
- carvedilol / Generic mfg.
Trial primary completion date: Trial of Carvedilol in Alzheimer's Disease (clinicaltrials.gov) - Feb 11, 2015
P4, N=50, Recruiting, Sponsor: Johns Hopkins University
Trial primary completion date: Dec 2013 --> Dec 2015 Trial primary completion date: Jun 2014 --> Dec 2015
- |||| Trial completion: Effects of Mental Stimulation in Patients With Mild Cognitive Impairment (clinicaltrials.gov) - Feb 11, 2015
P2, N=72, Completed, Sponsor: Johns Hopkins University
Trial primary completion date: Jun 2014 --> Dec 2015 Active, not recruiting --> Completed
- Trial completion, Enrollment change: ERGODEM: Effectiveness of Home Based Occupational Therapy for Dementia. (clinicaltrials.gov) - Feb 11, 2015
P=N/A, N=160, Completed, Sponsor: Technische Universität Dresden
Active, not recruiting --> Completed Recruiting --> Completed | N=200 --> 160
- haloperidol / Generic mfg., quetiapine / Generic mfg.
Trial primary completion date: Haloquet: Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium (clinicaltrials.gov) - Feb 10, 2015
P3, N=45, Recruiting, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting --> Completed | N=200 --> 160 Trial primary completion date: Mar 2014 --> Sep 2015
- || Enrollment change, Trial primary completion date: Effect of NeuroAD on the Cognitive Function of Alzheimer Patients (clinicaltrials.gov) - Feb 10, 2015
P=N/A, N=150, Recruiting, Sponsor: Neuronix Ltd
Trial primary completion date: Mar 2014 --> Sep 2015 N=120 --> 150 | Trial primary completion date: Dec 2014 --> Sep 2015
- Trial primary completion date: Apoe Impact Study on Brain Structure and Function, in a Population 45 to 75 Years Old (clinicaltrials.gov) - Feb 9, 2015
P=N/A, N=700, Recruiting, Sponsor: Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
N=120 --> 150 | Trial primary completion date: Dec 2014 --> Sep 2015 Trial primary completion date: Dec 2014 --> May 2015
- ||||| Enrollment closed, Trial primary completion date: Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment (clinicaltrials.gov) - Feb 9, 2015
P3, N=200, Active, not recruiting, Sponsor: Thomas Jefferson University
Trial primary completion date: Dec 2014 --> May 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Dec 2015
- || Trial primary completion date: Ammonia Levels and Cognitive Impairment (clinicaltrials.gov) - Feb 6, 2015
P=N/A, N=100, Recruiting, Sponsor: Duke University
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Dec 2014 --> Jun 2015
- sevoflurane / Generic mfg.
Trial completion, Surgery: HIPELD: Hip Fracture Surgery in Elderly Patients (clinicaltrials.gov) - Feb 6, 2015
P2, N=256, Completed, Sponsor: Air Liquide Sant
Trial primary completion date: Dec 2014 --> Jun 2015 Recruiting --> Completed
- || Trial primary completion date: Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline (clinicaltrials.gov) - Feb 5, 2015
P4, N=600, Active, not recruiting, Sponsor: Avid Radiopharmaceuticals
Recruiting --> Completed Trial primary completion date: Dec 2014 --> Mar 2015
- midodrine hydrochloride / Generic mfg.
Enrollment closed, Trial primary completion date: Body Temperature in Persons With Tetraplegia When Exposed to Cold (clinicaltrials.gov) - Feb 5, 2015
P4, N=30, Active, not recruiting, Sponsor: James J. Peters Veterans Affairs Medical Center
Trial primary completion date: Dec 2014 --> Mar 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2014 --> Feb 2015
- ||| Trial completion: POD-I: Incidence, Long- Term Outcome and Factor Related to Non- Cardiac Postoperative Delirium in Elderly Patients (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=400, Completed, Sponsor: Chiang Mai University
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2014 --> Feb 2015 Recruiting --> Completed
- | Trial completion, Enrollment change: An Observational Study for the Prevalence of Neuropsychiatric Symptom in Parkinson's Disease Dementia (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=48, Completed, Sponsor: The Catholic University of Korea
Recruiting --> Completed Recruiting --> Completed | N=60 --> 48
- Trial primary completion date: Florbetapir Calibration to the Centiloid Scale (clinicaltrials.gov) - Feb 5, 2015
P1, N=35, Recruiting, Sponsor: Avid Radiopharmaceuticals
Recruiting --> Completed | N=60 --> 48 Trial primary completion date: Nov 2014 --> May 2015
- Enrollment change, Trial termination: Effect of Raised CBF During CEA on Cognition in DM Patients (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=20, Terminated, Sponsor: Columbia University
Trial primary completion date: Nov 2014 --> May 2015 N=400 --> 20 | Recruiting --> Terminated; Half of DM patients had EEG changes and therefore were excluded.
- Trial completion, Trial primary completion date, Surgery: HTN: Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=200, Completed, Sponsor: Columbia University
N=400 --> 20 | Recruiting --> Terminated; Half of DM patients had EEG changes and therefore were excluded. Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Jan 2013
- Trial initiation date: Sound Estimation and Accuracy Task (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=600, Not yet recruiting, Sponsor: Carnegie Mellon University
Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Jan 2013 Initiation date: Nov 2014 --> Feb 2015
- S-equol (AUS-131) / Ausio Pharma
Enrollment open: S-Equol in Alzheimer's Disease (SEAD) Trial (clinicaltrials.gov) - Feb 2, 2015
P1, N=15, Recruiting, Sponsor: Russell Swerdlow, MD
Initiation date: Nov 2014 --> Feb 2015 Not yet recruiting --> Recruiting
- Clinical: Patients With Alzheimer Disease, Spouse Carers and Risk of Institutionalization: a Prospective Observational Cohort Study of Dyads (AID Study) (clinicaltrials.gov) - Jan 30, 2015
P=N/A, N=207, Completed, Sponsor: University Hospital, Angers
- || New P3 trial: Effects of Multimodal Cognitive Enhancement Therapy (MCET) for Ealy Dementia (clinicaltrials.gov) - Jan 30, 2015
P3, N=64, Active, not recruiting, Sponsor: Ki Woong Kim
- atabecestat (JNJ-54861911) / J&J
Trial primary completion date: A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease (clinicaltrials.gov) - Jan 30, 2015
P1, N=48, Recruiting, Sponsor: Janssen Research & Development, LLC
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2014 --> Apr 2015
- New P1 trial: 18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) - Jan 30, 2015
P1, N=10, Not yet recruiting, Sponsor: Avid Radiopharmaceuticals
- Trial primary completion date: AZAP: Sleep Apnea in Early to Mid-Stage Alzheimer's Disease (clinicaltrials.gov) - Jan 29, 2015
P=N/A, N=100, Recruiting, Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Trial primary completion date: Dec 2014 --> Apr 2015 Trial primary completion date: Mar 2015 --> Mar 2016
- Enrollment open, Trial initiation date, Trial primary completion date: Tau Imaging of Chronic Traumatic Encephalopathy (clinicaltrials.gov) - Jan 28, 2015
P2, N=30, Enrolling by invitation, Sponsor: Marcelo F. Di Carli, MD, FACC
Trial primary completion date: Mar 2015 --> Mar 2016 Not yet recruiting --> Enrolling by invitation | Initiation date: Aug 2014 --> Jan 2015 | Trial primary completion date: Oct 2016 --> Jun 2016
- |||| Nine Phase One (mannote sodium) / Shanghai Greenvalley
Trial completion: Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Jan 28, 2015
P2, N=255, Completed, Sponsor: Shanghai Greenvalley Pharmaceutical Co., Ltd.
Not yet recruiting --> Enrolling by invitation | Initiation date: Aug 2014 --> Jan 2015 | Trial primary completion date: Oct 2016 --> Jun 2016 Active, not recruiting --> Completed
- Trial completion, Enrollment change: Language Treatment for Progressive Aphasia (clinicaltrials.gov) - Jan 28, 2015
P=N/A, N=7, Completed, Sponsor: Baycrest
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=14 --> 7
- Trial primary completion date: Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids (clinicaltrials.gov) - Jan 28, 2015
P=N/A, N=50, Active, not recruiting, Sponsor: New York University School of Medicine
Active, not recruiting --> Completed | N=14 --> 7 Trial primary completion date: Jul 2014 --> Jul 2015
- Enrollment change: CROVCD: Cognitive Rehabilitation of Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) Veterans With Cognitive Disorder (clinicaltrials.gov) - Jan 26, 2015
P=N/A, N=128, Completed, Sponsor: Department of Veterans Affairs
Trial primary completion date: Jul 2014 --> Jul 2015 N=280 --> 128
- ||||| donepezil / Generic mfg.
New P4 trial, P4 data: A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB) (clinicaltrials.gov) - Jan 26, 2015
P4, N=140, Not yet recruiting, Sponsor: Eisai Co., Ltd.
- |||| osoresnontrine (BI 409306) / Boehringer Ingelheim
Enrollment open: Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo (clinicaltrials.gov) - Jan 26, 2015
P2, N=288, Recruiting, Sponsor: Boehringer Ingelheim
N=280 --> 128 Not yet recruiting --> Recruiting
- Enrollment closed, Metastases: A Pilot Study of an RCT to Improve Infection Management in Advanced Dementia (clinicaltrials.gov) - Jan 26, 2015
P2, N=60, Active, not recruiting, Sponsor: Hebrew Rehabilitation Center, Boston
Not yet recruiting --> Recruiting Not yet recruiting --> Active, not recruiting
- Leqembi (lecanemab) / Biogen, BioArctic, Eisai
Enrollment closed, Trial primary completion date, IO biomarker: A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease (clinicaltrials.gov) - Jan 26, 2015
P1, N=24, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Not yet recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Mar 2015
- P1 data, Trial primary completion date: DEMENSTIM: Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies (clinicaltrials.gov) - Jan 22, 2015
P1, N=6, Recruiting, Sponsor: University Hospital, Rouen
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Mar 2015 Trial primary completion date: Oct 2015 --> Oct 2017
- || Trial primary completion date, Combination therapy: Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI) (clinicaltrials.gov) - Jan 22, 2015
P4, N=330, Recruiting, Sponsor: Charite University, Berlin, Germany
Trial primary completion date: Oct 2015 --> Oct 2017 Trial primary completion date: Jul 2014 --> Jul 2015
- Clinical: SMART: Physical Activity and Cerebral Metabolism in the Elderly: a Randomised Controlled Trial (clinicaltrials.gov) - Jan 22, 2015
P=N/A, N=60, Recruiting, Sponsor: Professor Johannes Pantel
- ||||| PF-02545920 / Pfizer
New P2 trial: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 (clinicaltrials.gov) - Jan 22, 2015
P2, N=260, Not yet recruiting, Sponsor: Pfizer
- ||||||| dexmedetomidine / Generic mfg.
Clinical: DahLIA: Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation (clinicaltrials.gov) - Jan 22, 2015
P2/3, N=96, Completed, Sponsor: Austin Health
Trial primary completion date: Jul 2014 --> Jul 2015 Recruiting --> Completed | Trial primary completion date: Oct 2012 --> Dec 2013
- || MK-7622 / Merck (MSD)
Trial primary completion date: Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012) (clinicaltrials.gov) - Jan 22, 2015
P2a, N=830, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed | Trial primary completion date: Oct 2012 --> Dec 2013 Trial primary completion date: Aug 2017 --> Apr 2020
- Clinical: Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty (clinicaltrials.gov) - Jan 20, 2015
P=N/A, N=20, Recruiting, Sponsor: Military Institute of Medicine, Poland
- ||| Clinical: Implementation of a Multicomponent Intervention to Prevent Physical Restraints in Nursing Home Residents (IMPRINT) (clinicaltrials.gov) - Jan 20, 2015
P=N/A, N=10800, Not yet recruiting, Sponsor: University of Luebeck
- | Trial completion, Trial primary completion date: Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment (clinicaltrials.gov) - Jan 20, 2015
P2, N=48, Completed, Sponsor: Yale University
Trial primary completion date: Aug 2017 --> Apr 2020 Recruiting --> Completed | Trial primary completion date: Dec 2012 --> Dec 2014