|
122 Companies |
|
196 Products |
|
196 Products |
|
116 Mechanisms of Action |
|
3 Trials |
|
2338 News |
|
| «12...1314151617181920212223...4647» |
- Trial primary completion date: Evaluation of [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948 as Tracers for Positron Emission Tomography (PET) Imaging of Tau in Healthy and Alzheimer's Disease (AD) Participants (clinicaltrials.gov) - Apr 14, 2015
P1, N=34, Recruiting, Sponsor: Hoffmann-La Roche
Trial primary completion date: Oct 2015 --> Jun 2015
- Trial primary completion date: PET Imaging in MCI Following ADT for PCa (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=12, Recruiting, Sponsor: Imperial College London
Trial primary completion date: Oct 2015 --> Jun 2015 Trial primary completion date: Dec 2014 --> Oct 2015
- || lorazepam / Generic mfg.
Trial primary completion date: The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms (clinicaltrials.gov) - Apr 14, 2015
P1, N=75, Recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Dec 2014 --> Oct 2015 Trial primary completion date: Jan 2014 --> Oct 2015
- eltoprazine (DU 28853) / Amarantus BioSci, PsychoGenics, ReqMed
Trial completion, Enrollment change: Effects of Eltoprazine on Cognitive Impairment Associated With Schizophrenia (CIAS) in Adults (clinicaltrials.gov) - Apr 14, 2015
P2, N=31, Completed, Sponsor: Amarantus BioScience Holdings, Inc.
Trial primary completion date: Jan 2014 --> Oct 2015 Recruiting --> Completed | N=50 --> 31
- Biomarker, Trial completion: Functional MRI Biomarkers of Cognitive Decrements in Diabetes (clinicaltrials.gov) - Apr 10, 2015
P=N/A, N=106, Completed, Sponsor: Maastricht University Medical Center
Recruiting --> Completed | N=50 --> 31 Recruiting --> Completed
- || donepezil / Generic mfg.
Enrollment closed: Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Factors That Affect Aricept Medication Persistence Rate and the Safety and Efficacy in Patients With Alzheimer's Disease in Clinical Practice (clinicaltrials.gov) - Apr 8, 2015
P=N/A, N=10000, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Recruiting --> Completed Recruiting --> Active, not recruiting
- || memantine / Generic mfg.
Enrollment closed, Combination therapy: Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease (clinicaltrials.gov) - Apr 8, 2015
P=N/A, N=5000, Active, not recruiting, Sponsor: Eisai Co., Ltd.
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- Trial completion: NEORIS: Prematurity Related Risks of Cognitive Impairment at School Age (clinicaltrials.gov) - Apr 8, 2015
P=N/A, N=100, Completed, Sponsor: Jean Michel Hascoet
Recruiting --> Active, not recruiting Recruiting --> Completed
- | Trial completion, Enrollment change, Trial primary completion date: Exercise in Asymptomatic Pre-Alzheimer's Disease Pilot Study (clinicaltrials.gov) - Apr 8, 2015
P=N/A, N=16, Completed, Sponsor: Mayo Clinic
Recruiting --> Completed Recruiting --> Completed | N=20 --> 16 | Trial primary completion date: Nov 2015 --> Dec 2014
- Enrollment open: Music-with-Movement Intervention for People With Early Dementia and Their Families (clinicaltrials.gov) - Apr 7, 2015
P=N/A, N=134, Recruiting, Sponsor: The Hong Kong Polytechnic University
Recruiting --> Completed | N=20 --> 16 | Trial primary completion date: Nov 2015 --> Dec 2014 Not yet recruiting --> Recruiting
- Trial completion: Supporting Caregivers of Persons With Dementia: A Pilot Study (clinicaltrials.gov) - Apr 7, 2015
P2/3, N=38, Completed, Sponsor: McMaster University
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment closed: A Pre-Cellular Therapy Observational Study in Early Huntington's Disease (clinicaltrials.gov) - Apr 6, 2015
P=N/A, N=40, Active, not recruiting, Sponsor: University of California, Davis
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- Enrollment closed: Retaining Cognition While Avoiding Late-Life Depression (clinicaltrials.gov) - Apr 6, 2015
P=N/A, N=136, Active, not recruiting, Sponsor: University of Pittsburgh
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | Trial completion: Telehealth Education Program for Caregivers of Veterans With Dementia (clinicaltrials.gov) - Apr 5, 2015
P=N/A, N=160, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Active, not recruiting Recruiting --> Completed
- | Trial completion: Effect of Activity on Sleep of Cognitively-Impaired Veterans (clinicaltrials.gov) - Apr 5, 2015
P=N/A, N=90, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed Active, not recruiting --> Completed
- | paracetamol / Generic mfg.
Trial completion: Pain Management and Behavioral Outcomes in Patients With Dementia (clinicaltrials.gov) - Apr 5, 2015
P2, N=66, Completed, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Recruiting --> Completed
- | Trial completion: Nurse Managed Clinic for Dementia Patients and Family Caregivers (clinicaltrials.gov) - Apr 5, 2015
P=N/A, N=120, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed No longer recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date, HEOR: MBCT_AD: Mindfulness Research Program: Designed to Enhance Wellbeing in People Living With Dementia and Their Spouses (clinicaltrials.gov) - Apr 3, 2015
P=N/A, N=36, Completed, Sponsor: Lakehead University
No longer recruiting --> Completed Not yet recruiting --> Completed | N=60 --> 36 | Trial primary completion date: Apr 2014 --> Aug 2014
- ||||||| Trial completion, Trial primary completion date: ARTEMIDA: Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI) (clinicaltrials.gov) - Apr 3, 2015
P3, N=500, Completed, Sponsor: Takeda
Not yet recruiting --> Completed | N=60 --> 36 | Trial primary completion date: Apr 2014 --> Aug 2014 Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Nov 2014
- Enbrel (etanercept) / Pfizer, Amgen
Enrollment closed: Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease (clinicaltrials.gov) - Apr 3, 2015
P1, N=12, Active, not recruiting, Sponsor: Life Extension Foundation Inc.
Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Nov 2014 Recruiting --> Active, not recruiting
- Enrollment closed, Trial primary completion date: Wheelchair-bound Senior Elastic Band (WSEB) Exercise Program for the Demented Seniors (clinicaltrials.gov) - Apr 1, 2015
P=N/A, N=180, Active, not recruiting, Sponsor: Kaohsiung Medical University
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jul 2015
- Enrollment change: PRISM-PC: Perceptions Regarding Investigational Screening for Memory Problems in Primary Care (clinicaltrials.gov) - Mar 31, 2015
P=N/A, N=954, Completed, Sponsor: Indiana University
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jul 2015 N=1500 --> 954
- Enrollment open: An Exploratory Study to Compare the Differences in Nutritional Status Between Patients With Mild and Moderate Alzheimer's Disease (AD) and Cognitively Intact Healthy People in an Asian Population (clinicaltrials.gov) - Mar 31, 2015
P=N/A, N=225, Recruiting, Sponsor: PTSH Holding Singapore Pte Ltd
N=1500 --> 954 Not yet recruiting --> Recruiting
- ||| Trial completion, Trial primary completion date, Metastases: Palliative and End-of-life Care in Advanced Dementia: Evaluation of a Program of Organization of Care in Long-term Care (clinicaltrials.gov) - Mar 31, 2015
P=N/A, N=175, Completed, Sponsor: Laval University
Not yet recruiting --> Recruiting Recruiting --> Completed | Trial primary completion date: Jun 2014 --> Oct 2014
- ||||||| Trial completion: Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to Histopathology (clinicaltrials.gov) - Mar 28, 2015
P3, N=218, Completed, Sponsor: Piramal Imaging SA
Recruiting --> Completed | Trial primary completion date: Jun 2014 --> Oct 2014 Active, not recruiting --> Completed
- | donepezil transdermal patch (IPI-301) / Icure Pharm
Trial completion: A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects. (clinicaltrials.gov) - Mar 25, 2015
P1, N=24, Completed, Sponsor: Icure Pharmaceutical Inc.
Active, not recruiting --> Completed Not yet recruiting --> Completed
- | SAR228810 / Sanofi
Trial completion: Single and Repeated Dosing Study to Assess the Safety and the Concentration-time Profile of SAR228810 in Alzheimer's Patients (clinicaltrials.gov) - Mar 25, 2015
P1, N=48, Completed, Sponsor: Sanofi
Not yet recruiting --> Completed Active, not recruiting --> Completed
- | rivastigmine transdermal / Generic mfg.
Enrollment closed, Enrollment change: Rivastigmine in the Management of Delirium (clinicaltrials.gov) - Mar 23, 2015
P3, N=23, Active, not recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=440 --> 23
- Trial completion, Enrollment change: AD: A Positron Emission Tomography (PET) Study Evaluating Brain Metabolism of a Medical Food in Alzheimer's Disease (clinicaltrials.gov) - Mar 23, 2015
P4, N=17, Completed, Sponsor: University of California, Los Angeles
Recruiting --> Active, not recruiting | N=440 --> 23 Recruiting --> Completed | N=22 --> 17
- ||||| LMTX (hydromethylthionine) / TauRx
Enrollment closed, Enrollment change: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD) (clinicaltrials.gov) - Mar 20, 2015
P3, N=220, Active, not recruiting, Sponsor: TauRx Therapeutics Ltd
Recruiting --> Completed | N=22 --> 17 Recruiting --> Active, not recruiting | N=180 --> 220
- |||| PF-02545920 / Pfizer
Enrollment open: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 (clinicaltrials.gov) - Mar 18, 2015
P2, N=260, Recruiting, Sponsor: Pfizer
Recruiting --> Active, not recruiting | N=180 --> 220 Not yet recruiting --> Recruiting
- ||| Trial completion: PiB PET Scanning in Speech and Language Based Dementias (clinicaltrials.gov) - Mar 18, 2015
P=N/A, N=168, Completed, Sponsor: Mayo Clinic
Not yet recruiting --> Recruiting Recruiting --> Completed
- ||| donepezil / Generic mfg.
Enrollment closed: Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease (clinicaltrials.gov) - Mar 17, 2015
P4, N=171, Active, not recruiting, Sponsor: Eisai Korea Inc.
Recruiting --> Completed Recruiting --> Active, not recruiting
- ||| encenicline (EVP-6124) / Forum Pharmaceuticals, Mitsubishi Tanabe
Enrollment closed: Safety and Efficacy of MT-4666 (clinicaltrials.gov) - Mar 17, 2015
P2, N=450, Active, not recruiting, Sponsor: Mitsubishi Tanabe Pharma Corporation
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | Trial completion, Enrollment change: Mild Cognitive Impairment and Obstructive Sleep Apnea (clinicaltrials.gov) - Mar 17, 2015
P3, N=86, Completed, Sponsor: George Mason University
Recruiting --> Active, not recruiting Recruiting --> Completed | N=110 --> 86
- Enrollment closed: Meaningful Activity Intervention for Persons With Mild Cognitive Impairment (clinicaltrials.gov) - Mar 17, 2015
P1, N=72, Active, not recruiting, Sponsor: Indiana University
Recruiting --> Completed | N=110 --> 86 Recruiting --> Active, not recruiting
- PBF-999 / Palobiofarma
Trial primary completion date: Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers (clinicaltrials.gov) - Mar 12, 2015
P1, N=32, Recruiting, Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Recruiting --> Active, not recruiting Trial primary completion date: Nov 2014 --> Apr 2015
- Trial completion: Effects of Strengthening Exercise on the Brain for Early Dementia and Normative Older Adults (clinicaltrials.gov) - Mar 11, 2015
P=N/A, N=22, Completed, Sponsor: Union College, New York
Trial primary completion date: Nov 2014 --> Apr 2015 Recruiting --> Completed
- Trial primary completion date: 18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) - Mar 11, 2015
P1, N=10, Not yet recruiting, Sponsor: Avid Radiopharmaceuticals
Recruiting --> Completed Trial primary completion date: Feb 2016 --> May 2016
- Enrollment change, Trial termination, Trial primary completion date, FDG PET: Early Diagnosis of Alzheimer-like Dementia: Benefit of MRI and PET Imaging (clinicaltrials.gov) - Mar 10, 2015
P=N/A, N=60, Terminated, Sponsor: Centre Hospitalier Universitaire, Amiens
N=350 --> 60 | Suspended --> Terminated | Trial primary completion date: Jul 2014 --> Apr 2013; Administrative re-organization of the department. Referent physician left the hospital.
- Enrollment change: Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Alzheimer's Disease (clinicaltrials.gov) - Mar 10, 2015
P=N/A, N=0, Withdrawn, Sponsor: University Hospital, Basel, Switzerland
Referent physician left the hospital. N=80 --> 0
- haloperidol / Generic mfg.
Enrollment closed, Trial primary completion date: HARPOON: Haloperidol Prophylaxis in Older Emergency Department Patients (clinicaltrials.gov) - Mar 5, 2015
P4, N=780, Active, not recruiting, Sponsor: VU University Medical Center
N=80 --> 0 Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2015 --> Mar 2015
- Enrollment change: 2-StaLi: Cognitive Outcome After Two-stage Liver-Operation (clinicaltrials.gov) - Mar 3, 2015
P=N/A, N=30, Recruiting, Sponsor: Charite University, Berlin, Germany
Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2015 --> Mar 2015 N=20 --> 30
- rivastigmine transdermal / Generic mfg.
Trial completion: Mild Cognitive Impairment in Parkinson's Disease (clinicaltrials.gov) - Feb 27, 2015
P4, N=28, Completed, Sponsor: University of Pennsylvania
N=20 --> 30 Recruiting --> Completed
- Enrollment change: Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment. (clinicaltrials.gov) - Feb 27, 2015
P2, N=143, Completed, Sponsor: National Institute of Mental Health (NIMH)
Recruiting --> Completed N=100 --> 143
- || donanemab (LY3002813) / Eli Lilly
Enrollment closed: A Study of LY3002813 in Participants With Alzheimer's Disease (clinicaltrials.gov) - Feb 27, 2015
P1, N=100, Active, not recruiting, Sponsor: Eli Lilly and Company
N=100 --> 143 Recruiting --> Active, not recruiting
- Trial completion: ALSTIMAG: Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as add-on Treatment for Early Alzheimer's Disease (clinicaltrials.gov) - Feb 27, 2015
P=N/A, N=15, Completed, Sponsor: Pierre Vandel, MD PhD
Recruiting --> Active, not recruiting Recruiting --> Completed
- |||| verubecestat (MK-8931) / Merck (MSD)
Trial primary completion date: EPOCH: An Efficacy and Safety Trial of Verubecestat (MK-8931) in Mild to Moderate Alzheimer's Disease (P07738) (clinicaltrials.gov) - Feb 23, 2015
P2/3, N=1960, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed Trial primary completion date: Apr 2017 --> Jul 2017
- ||| Enrollment closed, Trial primary completion date: CBTAC: Cognitive-Behavioral Treatment for Mild Alzheimer's Patients and Their Caregivers (clinicaltrials.gov) - Feb 20, 2015
P2, N=124, Active, not recruiting, Sponsor: University of Zurich
Trial primary completion date: Apr 2017 --> Jul 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2013 --> Nov 2016
- | PF-02545920 / Pfizer
Trial completion, Enrollment change, Trial primary completion date: Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease (clinicaltrials.gov) - Feb 19, 2015
P2, N=37, Completed, Sponsor: Pfizer
Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2013 --> Nov 2016 Recruiting --> Completed | N=56 --> 37 | Trial primary completion date: Nov 2015 --> Jan 2015