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122 Companies |
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196 Products |
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196 Products |
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116 Mechanisms of Action |
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3 Trials |
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2338 News |
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- || donepezil / Generic mfg.
Trial primary completion date: A Multi-national Study to Identify Treatment Discontinuation Rate in de Novo Alzheimer's Disease Patients Who Have Been Newly Prescribed With Donepezil (Aricept) in Asia (ADOS) (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=700, Recruiting, Sponsor: Eisai Korea Inc.
Trial primary completion date: Apr 2016 --> Jul 2016
- Enrollment change, Trial withdrawal: Reminiscence, Anxiety and Early Alzheimer's Disease (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=0, Withdrawn, Sponsor: Emory University
Trial primary completion date: Apr 2016 --> Jul 2016 N=100 --> 0 | Not yet recruiting --> Withdrawn
- midodrine hydrochloride / Generic mfg.
Trial primary completion date: Body Temperature in Persons With Tetraplegia When Exposed to Cold (clinicaltrials.gov) - Jun 25, 2015
P4, N=30, Active, not recruiting, Sponsor: James J. Peters Veterans Affairs Medical Center
N=100 --> 0 | Not yet recruiting --> Withdrawn Trial primary completion date: Apr 2015 --> Aug 2015
- | atabecestat (JNJ-54861911) / J&J
Trial completion: A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease (clinicaltrials.gov) - Jun 25, 2015
P1, N=45, Completed, Sponsor: Janssen Research & Development, LLC
Trial primary completion date: Apr 2015 --> Aug 2015 Recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Cognitive Dysfunction in Postural Tachycardia Syndrome (clinicaltrials.gov) - Jun 24, 2015
P=N/A, N=60, Completed, Sponsor: Vanderbilt University
Recruiting --> Completed Active, not recruiting --> Completed | N=85 --> 60 | Trial primary completion date: Mar 2018 --> Jun 2015
- lisdexamfetamine / Generic mfg.
Trial primary completion date: LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy (clinicaltrials.gov) - Jun 23, 2015
P=N/A, N=20, Recruiting, Sponsor: University of Pennsylvania
Active, not recruiting --> Completed | N=85 --> 60 | Trial primary completion date: Mar 2018 --> Jun 2015 Trial primary completion date: Jul 2015 --> Oct 2017
- Trial primary completion date: Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness Disorders (clinicaltrials.gov) - Jun 18, 2015
P1, N=10, Recruiting, Sponsor: University Hospital of Ferrara
Trial primary completion date: Jul 2015 --> Oct 2017 Trial primary completion date: May 2015 --> Mar 2016
- Trial primary completion date: TMS-AD: Enhancing Neuroplasticity and Frontal Lobe Function in Patients With Mild Alzheimer's Disease (clinicaltrials.gov) - Jun 17, 2015
P2, N=56, Recruiting, Sponsor: Centre for Addiction and Mental Health
Trial primary completion date: May 2015 --> Mar 2016 Trial primary completion date: Oct 2014 --> Oct 2015
- Trial completion: Wheelchair-bound Senior Elastic Band (WSEB) Exercise Program for the Demented Seniors (clinicaltrials.gov) - Jun 16, 2015
P=N/A, N=150, Completed, Sponsor: Kaohsiung Medical University
Trial primary completion date: Oct 2014 --> Oct 2015 Active, not recruiting --> Completed
- |||| Trial completion: Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study) (clinicaltrials.gov) - Jun 16, 2015
P2, N=54, Completed, Sponsor: Charite University, Berlin, Germany
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Epidemiology of Depression, Anxiety, and Cognitive Impairment (clinicaltrials.gov) - Jun 15, 2015
P=N/A, N=1206, Completed, Sponsor: University of Rochester
Active, not recruiting --> Completed N=1600 --> 1206
- HTL0009936 / Sosei
Trial completion, Trial primary completion date: Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment (clinicaltrials.gov) - Jun 12, 2015
P1, N=108, Completed, Sponsor: Heptares Therapeutics Limited
N=1600 --> 1206 Active, not recruiting --> Completed | Trial primary completion date: Jun 2015 --> Jul 2014
- Trial primary completion date: Distance Savvy: Testing Tele-Savvy, a Distance Dementia Family Caregiver Education Program (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=75, Recruiting, Sponsor: Emory University
Active, not recruiting --> Completed | Trial primary completion date: Jun 2015 --> Jul 2014 Trial primary completion date: Apr 2015 --> Sep 2015
- Trial primary completion date: Impact of Pharmacotherapy Management in Patients With Alzheimer's Disease (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=160, Recruiting, Sponsor: Universidade Estadual Paulista Júlio de Mesquita Filho
Trial primary completion date: Apr 2015 --> Sep 2015 Trial primary completion date: Oct 2014 --> Oct 2015
- Trial primary completion date: PET Imaging in Chronic Traumatic Encephalopathy (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=40, Recruiting, Sponsor: National Institute of Mental Health (NIMH)
Trial primary completion date: Oct 2014 --> Oct 2015 Trial primary completion date: May 2015 --> Sep 2015
- Trial primary completion date: Short-term Caregiver Psychotherapy (clinicaltrials.gov) - Jun 11, 2015
P2, N=20, Recruiting, Sponsor: University of Rostock
Trial primary completion date: May 2015 --> Sep 2015 Trial primary completion date: Apr 2015 --> Oct 2015
- donepezil / Generic mfg.
Trial primary completion date: Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318) (clinicaltrials.gov) - Jun 11, 2015
P2, N=36, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
Trial primary completion date: Apr 2015 --> Oct 2015 Trial primary completion date: Nov 2015 --> Apr 2016
- Trial primary completion date: ICTUS: Transient Global Amnesia (TGA). Exploratory Study of the Default Mode Network During the Acute Phase (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=44, Recruiting, Sponsor: University Hospital, Toulouse
Trial primary completion date: Nov 2015 --> Apr 2016 Trial primary completion date: Dec 2014 --> Dec 2015
- olanzapine / Generic mfg., haloperidol / Generic mfg.
Trial primary completion date, Metastases: Early Recognition and Optimal Treatment of Delirium in Patients With Advanced Cancer (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=300, Recruiting, Sponsor: VU University Medical Center
Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Aug 2014 --> Aug 2015
- haloperidol / Generic mfg.
Trial primary completion date: HARPOON: Haloperidol Prophylaxis in Older Emergency Department Patients (clinicaltrials.gov) - Jun 11, 2015
P4, N=780, Active, not recruiting, Sponsor: VU University Medical Center
Trial primary completion date: Aug 2014 --> Aug 2015 Trial primary completion date: Mar 2015 --> Sep 2015
- divalproex sodium XR / Generic mfg., quetiapine / Generic mfg.
Trial withdrawal: Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients (clinicaltrials.gov) - Jun 11, 2015
P4, N=0, Withdrawn, Sponsor: University of Cincinnati
Trial primary completion date: Mar 2015 --> Sep 2015 Terminated --> Withdrawn
- Trial suspension: The Genetic Characterization of Dementia (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=300, Suspended, Sponsor: National Institute on Aging (NIA)
Terminated --> Withdrawn Recruiting --> Suspended
- Trial initiation date, HEOR: Molecular Cerebral Imaging in Incipient Dementia (MCI-ID) II (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=1500, Not yet recruiting, Sponsor: University of California, Los Angeles
Recruiting --> Suspended Initiation date: Jan 2015 --> Nov 2015
- davunetide intranasal (AL-108) / Endo
Trial primary completion date: Davunetide (AL-108) in Predicted Tauopathies - Pilot Study (clinicaltrials.gov) - Jun 11, 2015
P2, N=12, Active, not recruiting, Sponsor: University of California, San Francisco
Initiation date: Jan 2015 --> Nov 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- Trial primary completion date: FPEB: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (clinicaltrials.gov) - Jun 11, 2015
P1, N=155, Recruiting, Sponsor: Institute for Neurodegenerative Disorders
Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- Enrollment open, Trial primary completion date: 18F-AV-1451 High Resolution Autopsy Study (clinicaltrials.gov) - Jun 11, 2015
P1, N=10, Recruiting, Sponsor: Avid Radiopharmaceuticals
Trial primary completion date: Dec 2014 --> Dec 2015 Not yet recruiting --> Recruiting | Trial primary completion date: May 2016 --> Nov 2016
- ||| Trial completion, Enrollment change: Two Interventions for Early Stage Dementia: A Comparative Efficacy Trial (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=152, Completed, Sponsor: University of Washington
Not yet recruiting --> Recruiting | Trial primary completion date: May 2016 --> Nov 2016 Active, not recruiting --> Completed | N=240 --> 152
- ||||| rivastigmine transdermal / Generic mfg.
Enrollment change: Randomized, Double-blind Study to Evaluate the Tolerability of 2 Different Titration Methods of Rivastigmine Patch in AD Patients (MMSE 10-20) (clinicaltrials.gov) - Jun 6, 2015
P3, N=216, Completed, Sponsor: Novartis Pharmaceuticals
Active, not recruiting --> Completed | N=240 --> 152 N=101 --> 216
- | Leqembi (lecanemab) / Biogen, BioArctic, Eisai
Trial completion, IO biomarker: A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease (clinicaltrials.gov) - Jun 6, 2015
P1, N=26, Completed, Sponsor: Eisai Co., Ltd.
N=101 --> 216 Active, not recruiting --> Completed
- Enrollment open: ATP in Alzheimer Disease (clinicaltrials.gov) - Jun 4, 2015
P2, N=20, Recruiting, Sponsor: Sara Varea
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment closed: DanceFit;DanceFit Prime: DanceFit Prime: A Dance Based Physical Activity and Nutritional Intervention for Primary Care - A Feasibility Study (clinicaltrials.gov) - Jun 4, 2015
P=N/A, N=40, Active, not recruiting, Sponsor: North Essex Partnership NHS Foundation Trust
Not yet recruiting --> Recruiting Not yet recruiting --> Active, not recruiting
- acetylcysteine solution / Generic mfg.
Trial completion: NACSZ: N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia (clinicaltrials.gov) - Jun 4, 2015
P1, N=26, Completed, Sponsor: VA Greater Los Angeles Healthcare System
Not yet recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||| Enrollment closed, Trial primary completion date: Efficacy and Safety of Fufangdanshen Tablets in Mild to Moderate Vascular Dementia (clinicaltrials.gov) - Jun 3, 2015
P2, N=240, Active, not recruiting, Sponsor: Dongzhimen Hospital, Beijing
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2013 --> Dec 2015
- Trial completion, Enrollment change, Surgery: The Delirium-CS Canada Study (clinicaltrials.gov) - Jun 1, 2015
P=N/A, N=234, Completed, Sponsor: St. Boniface General Hospital Research Centre
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2013 --> Dec 2015 Not yet recruiting --> Completed | N=3000 --> 234
- Trial completion, Enrollment change, Trial primary completion date: Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians (clinicaltrials.gov) - Jun 1, 2015
P=N/A, N=86, Completed, Sponsor: University of Lausanne
Not yet recruiting --> Completed | N=3000 --> 234 Not yet recruiting --> Completed | N=155 --> 86 | Trial primary completion date: Nov 2013 --> Nov 2014
- | Targretin oral (bexarotene oral) / ReXceptor
Trial completion, Trial primary completion date: BEAT-AD: Bexarotene Amyloid Treatment for Alzheimer's Disease (clinicaltrials.gov) - Jun 1, 2015
P2, N=20, Completed, Sponsor: The Cleveland Clinic
Not yet recruiting --> Completed | N=155 --> 86 | Trial primary completion date: Nov 2013 --> Nov 2014 Active, not recruiting --> Completed | Trial primary completion date: Dec 2013 --> Aug 2014
- ||| Enrollment open: IGF and Other Neurotrophic Factors in Patients With Dementia (clinicaltrials.gov) - May 29, 2015
P=N/A, N=120, Recruiting, Sponsor: University of Aarhus
Active, not recruiting --> Completed | Trial primary completion date: Dec 2013 --> Aug 2014 Not yet recruiting --> Recruiting
- Trial completion, Enrollment change: Health Technology Assessment of Diagnostic Approaches in Alzheimer's Disease (clinicaltrials.gov) - May 28, 2015
P=N/A, N=304, Completed, Sponsor: Maastricht University Medical Center
Not yet recruiting --> Recruiting Recruiting --> Completed | N=200 --> 304
- Trial completion: Reducing Caregiver Stress and Sleep Disturbances in Patients With Progressive Dementia (clinicaltrials.gov) - May 28, 2015
P1, N=60, Completed, Sponsor: Kathy Kennedy
Recruiting --> Completed | N=200 --> 304 Active, not recruiting --> Completed
- AADvac1 / Axon Neurosci
Enrollment closed: FUNDAMANT: 18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease (clinicaltrials.gov) - May 28, 2015
P1, N=25, Active, not recruiting, Sponsor: Axon Neuroscience SE
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||||| Nivadil (nilvadipine) / Cortice Biosci
Enrollment closed, P3 data, Trial primary completion date: A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease (clinicaltrials.gov) - May 27, 2015
P3, N=500, Active, not recruiting, Sponsor: Prof Brian Lawlor
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Sep 2016
- | Biomarker, Trial completion, Trial primary completion date: Olfactory Neuroepithelial Tissue of Alzheimer Disease (clinicaltrials.gov) - May 27, 2015
P=N/A, N=40, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Sep 2016 Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Dec 2014
- Tasigna (nilotinib) / Novartis, Inhibikase
Trial completion, Trial primary completion date: Nilotinib in Cognitively Impaired Parkinson Disease Patients 001 (clinicaltrials.gov) - May 26, 2015
P1, N=36, Completed, Sponsor: Georgetown University
Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Dec 2014 Recruiting --> Completed | Trial primary completion date: Sep 2015 --> May 2015
- |||| donepezil / Generic mfg.
Enrollment open, P4 data: A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB) (clinicaltrials.gov) - May 21, 2015
P4, N=140, Recruiting, Sponsor: Eisai Co., Ltd.
Recruiting --> Completed | Trial primary completion date: Sep 2015 --> May 2015 Not yet recruiting --> Recruiting
- Trial completion: Sound Estimation and Accuracy Task (clinicaltrials.gov) - May 21, 2015
P=N/A, N=600, Completed, Sponsor: Carnegie Mellon University
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- prazosin / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Prazosin Treatment for Disruptive Agitation in Alzheimer's Disease (clinicaltrials.gov) - May 21, 2015
P=N/A, N=20, Completed, Sponsor: Seattle Institute for Biomedical and Clinical Research
Not yet recruiting --> Completed Recruiting --> Completed | N=120 --> 20 | Trial primary completion date: Jul 2015 --> Mar 2014
- || Enrollment change: Assessment and Rehabilitation of Cognitive Impairments in Pediatric Survivors of Cancer (clinicaltrials.gov) - May 21, 2015
P=N/A, N=72, Completed, Sponsor: Stanford University
Recruiting --> Completed | N=120 --> 20 | Trial primary completion date: Jul 2015 --> Mar 2014 N=23 --> 72
- | AADvac1 / Axon Neurosci
Trial completion: Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease (clinicaltrials.gov) - May 20, 2015
P1, N=30, Completed, Sponsor: Axon Neuroscience SE
N=23 --> 72 Active, not recruiting --> Completed
- Enrollment closed, Trial primary completion date: Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation (clinicaltrials.gov) - May 19, 2015
P1, N=100, Active, not recruiting, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Not yet recruiting --> Active, not recruiting | Trial primary completion date: Jul 2014 --> Dec 2016
- Trial completion, Trial primary completion date: Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL) (clinicaltrials.gov) - May 19, 2015
P=N/A, N=160, Completed, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Active, not recruiting | Trial primary completion date: Jul 2014 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2014