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40 Companies |
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26 Products |
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26 Products |
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26 Mechanisms of Action |
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1 Trial |
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852 News |
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- | Victoza (liraglutide) / Novo Nordisk, Lyxumia (lixisenatide) / Zealand Pharma, Sanofi
Trial completion date, Trial primary completion date: Effects of Victoza (clinicaltrials.gov) - Mar 5, 2018
P1, N=72, Active, not recruiting, Sponsor: Profil Institut f
Trial completion date: Jan 2018 --> Apr 2018 | Trial primary completion date: Jan 2018 --> Apr 2018
- | Trial termination: Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux (clinicaltrials.gov) - Feb 20, 2018
P=N/A, N=30, Terminated, Sponsor: University of Massachusetts, Worcester
Suspended --> Terminated; IRB approval not renewed/approval lapsed. Prior status: insufficient enrollment; study suspended pending analysis
- | Enrollment closed, Trial completion date, Trial primary completion date: Cough According to Stimulus Type in PD (clinicaltrials.gov) - Feb 19, 2018
P1, N=158, Active, not recruiting, Sponsor: University of Florida
Prior status: insufficient enrollment; study suspended pending analysis Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2018 --> Feb 2017 | Trial completion date: Apr 2018 --> Feb 2019
- | Trial completion date, Trial initiation date, Trial primary completion date: Sensorimotor Dysfunction in Achalasia (clinicaltrials.gov) - Feb 13, 2018
P=N/A, N=50, Not yet recruiting, Sponsor: Mayo Clinic
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2018 --> Feb 2017 | Trial completion date: Apr 2018 --> Feb 2019 Initiation date: Oct 2016 --> Mar 2018 | Trial primary completion date: May 2017 --> May 2019 | Trial completion date: Aug 2017 --> Aug 2019
- | Clinical data, Enrollment open, Trial initiation date: Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes (clinicaltrials.gov) - Jan 26, 2018
P=N/A, N=448, Recruiting, Sponsor: Cedars-Sinai Medical Center
Initiation date: Oct 2016 --> Mar 2018 | Trial primary completion date: May 2017 --> May 2019 | Trial completion date: Aug 2017 --> Aug 2019 Not yet recruiting --> Recruiting | Initiation date: Jan 2017 --> Apr 2017
- | Trial primary completion date: SIRUP: Stretta In Reflux Uncontrolled by IPP (clinicaltrials.gov) - Jan 24, 2018
P=N/A, N=60, Recruiting, Sponsor: Nantes University Hospital
Not yet recruiting --> Recruiting | Initiation date: Jan 2017 --> Apr 2017 Trial primary completion date: Jun 2018 --> Oct 2018
- | Trial primary completion date: Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study (clinicaltrials.gov) - Jan 18, 2018
P=N/A, N=52, Terminated, Sponsor: Midwest Biomedical Research Foundation
Trial primary completion date: Jun 2018 --> Oct 2018 Trial primary completion date: Sep 2017 --> May 2017
- | Trial primary completion date: Narrow Band Imaging Project on Barrett's Esophagus (clinicaltrials.gov) - Jan 18, 2018
P=N/A, N=50, Recruiting, Sponsor: Midwest Biomedical Research Foundation
Trial primary completion date: Sep 2017 --> May 2017 Trial primary completion date: Dec 2017 --> Dec 2018
- | Enrollment change, HEOR: Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux Disease (clinicaltrials.gov) - Jan 18, 2018
P=N/A, N=89, Terminated, Sponsor: Midwest Biomedical Research Foundation
Trial primary completion date: Dec 2017 --> Dec 2018 N=384 --> 89
- Takecab (vonoprazan) / Takeda, Phathom Pharma
Trial completion: VISTAEXE: Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation (clinicaltrials.gov) - Jan 17, 2018
P4, N=3, Completed, Sponsor: Takeda
N=384 --> 89 Active, not recruiting --> Completed
- | Phase classification, Enrollment change, Trial withdrawal: Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders (clinicaltrials.gov) - Jan 12, 2018
P=N/A, N=0, Withdrawn, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed Phase classification: P2 --> P=N/A | N=50 --> 0 | Recruiting --> Withdrawn
- | Enrollment open: Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets (clinicaltrials.gov) - Jan 10, 2018
P4, N=48, Recruiting, Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Phase classification: P2 --> P=N/A | N=50 --> 0 | Recruiting --> Withdrawn Active, not recruiting --> Recruiting
- Trial primary completion date, Surgery: STAR Registry: Registry to Compare Two Surgical Treatments for GERD (clinicaltrials.gov) - Jan 9, 2018
P=N/A, N=46, Terminated, Sponsor: American Gastroenterological Association
Active, not recruiting --> Recruiting Trial primary completion date: Jul 2018 --> Apr 2017
- | Trial completion: POEM Anterior Versus Posterior Approach (clinicaltrials.gov) - Jan 2, 2018
P=N/A, N=150, Completed, Sponsor: Johns Hopkins University
Trial primary completion date: Jul 2018 --> Apr 2017 Active, not recruiting --> Completed
- | Trial completion, Enrollment change: Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS) (clinicaltrials.gov) - Dec 21, 2017
P1, N=21, Completed, Sponsor: University of Florida
Active, not recruiting --> Completed Recruiting --> Completed | N=120 --> 21
- | Trial completion, Enrollment change, Trial primary completion date: Swallowing Function, Oral Health, and Food Intake in Old Age (clinicaltrials.gov) - Dec 18, 2017
P=N/A, N=116, Completed, Sponsor: Ume
Recruiting --> Completed | N=120 --> 21 Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017 | Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017 | Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017
- | Trial completion: Transversalis Fascial Plane Nerve Block in Iliac Crest Bone Graft (clinicaltrials.gov) - Dec 15, 2017
P=N/A, N=56, Completed, Sponsor: University Health Network, Toronto
Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017 | Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017 | Recruiting --> Completed | N=70 --> 116 | Trial primary completion date: Jun 2018 --> Nov 2017 Recruiting --> Completed
- ||| Trial completion, Preclinical, Trial primary completion date: PEPTESTCN: Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERD (clinicaltrials.gov) - Dec 8, 2017
P=N/A, N=1032, Completed, Sponsor: MAAB (Shanghai) Medical Device Limited
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Apr 2017 --> Jan 2017
- | Enrollment open: Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders (clinicaltrials.gov) - Dec 7, 2017
P2, N=50, Recruiting, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed | Trial primary completion date: Apr 2017 --> Jan 2017 Not yet recruiting --> Recruiting
- Takecab (vonoprazan) / Takeda, Phathom Pharma
Enrollment closed, Enrollment change: VISTAEXE: Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation (clinicaltrials.gov) - Nov 29, 2017
P4, N=3, Active, not recruiting, Sponsor: Takeda
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | N=25 --> 3
- | Victoza (liraglutide) / Novo Nordisk, Lyxumia (lixisenatide) / Zealand Pharma, Sanofi
Trial primary completion date: Effects of Victoza (clinicaltrials.gov) - Nov 27, 2017
P1, N=72, Active, not recruiting, Sponsor: Profil Institut f
Recruiting --> Active, not recruiting | N=25 --> 3 Trial primary completion date: Oct 2017 --> Jan 2018
- | Trial completion, Trial primary completion date, Surgery, Bariatric surgery: Study of Gastro-oesophageal Reflux in Patients Having Had Bariatric Surgery (clinicaltrials.gov) - Nov 22, 2017
P=N/A, N=400, Completed, Sponsor: Pierre Wauthy
Trial primary completion date: Oct 2017 --> Jan 2018 Not yet recruiting --> Completed | Trial primary completion date: Apr 2018 --> Jun 2017
- | Trial completion: The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms" (clinicaltrials.gov) - Nov 22, 2017
P=N/A, N=248, Completed, Sponsor: Royal Marsden NHS Foundation Trust
Not yet recruiting --> Completed | Trial primary completion date: Apr 2018 --> Jun 2017 Active, not recruiting --> Completed
- | famotidine / Generic mfg., ranitidine hydrochloride / Generic mfg.
Enrollment change, Trial withdrawal: In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms? (clinicaltrials.gov) - Nov 18, 2017
P=N/A, N=0, Withdrawn, Sponsor: Stanford University
Active, not recruiting --> Completed N=106 --> 0 | Recruiting --> Withdrawn
- ||| Trial completion: SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01) (clinicaltrials.gov) - Nov 14, 2017
P=N/A, N=100, Completed, Sponsor: United Pharmaceuticals
N=106 --> 0 | Recruiting --> Withdrawn Active, not recruiting --> Completed
- | Trial completion: Laryngeal Mask Airway (LMA) Protector for Minimally Invasive Thyroidectomy (clinicaltrials.gov) - Nov 14, 2017
P=N/A, N=79, Completed, Sponsor: 424 General Military Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- | Trial completion, Trial primary completion date: Influence of Intrapulmonary Percussive Ventilation (IPV) on Gastro-oesophageal Reflux (GOR). (clinicaltrials.gov) - Nov 8, 2017
P=N/A, N=50, Completed, Sponsor: Vrije Universiteit Brussel
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Oct 2017
- | Trial completion, Enrollment change: Efficacy of Natural Ingredient to Improve the Swallowing Response of Patients With Oropharyngeal Dysphagia (clinicaltrials.gov) - Oct 26, 2017
P=N/A, N=104, Completed, Sponsor: Nestl
Recruiting --> Completed | Trial primary completion date: Oct 2018 --> Oct 2017 Recruiting --> Completed | N=84 --> 104
- | Trial primary completion date: EMST and TMS for Treatment of Dysphagia in Parkinson's Disease (clinicaltrials.gov) - Oct 25, 2017
P=N/A, N=40, Recruiting, Sponsor: University Hospital Muenster
Recruiting --> Completed | N=84 --> 104 Trial primary completion date: Aug 2017 --> May 2018
- | Kenalog-10 (triamcinolone acetonide) / BMS
Trial completion: Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection (clinicaltrials.gov) - Oct 24, 2017
P=N/A, N=10, Completed, Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Trial primary completion date: Aug 2017 --> May 2018 Active, not recruiting --> Completed
- | Trial completion, Enrollment change: Cardiaplication: A Novel Antireflux Operation (clinicaltrials.gov) - Oct 24, 2017
P=N/A, N=8, Completed, Sponsor: Emory University
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=20 --> 8
- Trial primary completion date: RELIEF Europe Study (clinicaltrials.gov) - Oct 16, 2017
P=N/A, N=7, Terminated, Sponsor: Torax Medical Incorporated
Active, not recruiting --> Completed | N=20 --> 8 Trial primary completion date: Aug 2017 --> Feb 2017
- | Trial primary completion date: [Impedance Measurement for Non-Erosive Reflux Disease (clinicaltrials.gov) - Oct 11, 2017
P=N/A, N=40, Enrolling by invitation, Sponsor: Mayo Clinic
Trial primary completion date: Aug 2017 --> Feb 2017 Trial primary completion date: Aug 2017 --> Aug 2018
- Enrollment change, Trial termination, Trial primary completion date: Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients (clinicaltrials.gov) - Oct 6, 2017
P3, N=16, Terminated, Sponsor: Reckitt Benckiser Healthcare (UK) Limited
Trial primary completion date: Aug 2017 --> Aug 2018 N=88 --> 16 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2017; Problems with recruitment
- | Trial completion, Enrollment change: Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia (clinicaltrials.gov) - Oct 5, 2017
P=N/A, N=35, Completed, Sponsor: Nestl
N=88 --> 16 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2017; Problems with recruitment Recruiting --> Completed | N=47 --> 35
- | Trial initiation date: Effect of Different Viscous Foods and Liquids on Swallowing Sounds (clinicaltrials.gov) - Sep 25, 2017
P=N/A, N=38, Not yet recruiting, Sponsor: University of Nebraska
Recruiting --> Completed | N=47 --> 35 Initiation date: Jun 2017 --> Sep 2018
- | Trial primary completion date: Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft (clinicaltrials.gov) - Sep 20, 2017
P4, N=50, Completed, Sponsor: Oregon Health and Science University
Initiation date: Jun 2017 --> Sep 2018 Trial primary completion date: May 2013 --> May 2015
- | Varithena (polidocanol injectable foam) / Boston Scientific
Enrollment change, Trial withdrawal, Trial primary completion date: Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs (clinicaltrials.gov) - Sep 15, 2017
P4, N=0, Withdrawn, Sponsor: OhioHealth
Trial primary completion date: May 2013 --> May 2015 N=60 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Apr 2018 --> Sep 2017
- | Trial suspension, Trial primary completion date, HEOR: Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer (clinicaltrials.gov) - Sep 1, 2017
P=N/A, N=100, Suspended, Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
N=60 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Apr 2018 --> Sep 2017 Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Jun 2019
- | Trial primary completion date: Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer (clinicaltrials.gov) - Aug 31, 2017
P2, N=163, Completed, Sponsor: Radiation Therapy Oncology Group
Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Jun 2019 Trial primary completion date: Nov 2014 --> Feb 2014
- | Takecab (vonoprazan) / Takeda, Phathom Pharma
Trial initiation date: VISTAEXE: Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation (clinicaltrials.gov) - Aug 30, 2017
P4, N=25, Recruiting, Sponsor: Takeda
Trial primary completion date: Nov 2014 --> Feb 2014 Initiation date: Apr 2017 --> Aug 2017
- | Trial completion, Trial primary completion date, Surgery: Reducing Dysphagia Associated With Anterior Cervical Spine Surgery by Maintaining Low Endotracheal Tube Cuff Pressure (clinicaltrials.gov) - Aug 28, 2017
P=N/A, N=40, Completed, Sponsor: Lawson Health Research Institute
Initiation date: Apr 2017 --> Aug 2017 Recruiting --> Completed | Trial primary completion date: Aug 2011 --> Jul 2013
- | Derazol DDR (dexrabeprazole) / Neutec
Trial completion: The Effect of Dexrabeprazole on Intragastric and Intraesophageal Acidity (clinicaltrials.gov) - Aug 24, 2017
P4, N=12, Completed, Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Recruiting --> Completed | Trial primary completion date: Aug 2011 --> Jul 2013 Recruiting --> Completed
- | Enrollment closed: Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets (clinicaltrials.gov) - Aug 24, 2017
P4, N=48, Active, not recruiting, Sponsor: Neutec Ar-Ge San ve Tic A.Ş
Recruiting --> Completed Not yet recruiting --> Active, not recruiting
- Enrollment change, Trial initiation date, Trial termination: NewBreez for Airway Protection in Head and Neck Cancer Patients With Chronic Aspiration (clinicaltrials.gov) - Aug 24, 2017
P=N/A, N=2, Terminated, Sponsor: ProTiP Medical
Not yet recruiting --> Active, not recruiting N=12 --> 2 | Initiation date: May 2015 --> Mar 2016 | Not yet recruiting --> Terminated; Recruitment rates too low to continue with the study
- | Victoza (liraglutide) / Novo Nordisk, Lyxumia (lixisenatide) / Zealand Pharma, Sanofi
Trial primary completion date: Effects of Victoza (clinicaltrials.gov) - Aug 22, 2017
P1, N=72, Active, not recruiting, Sponsor: Profil Institut f
N=12 --> 2 | Initiation date: May 2015 --> Mar 2016 | Not yet recruiting --> Terminated; Recruitment rates too low to continue with the study Trial primary completion date: Jul 2017 --> Oct 2017
- | Trial completion, Enrollment change, Trial primary completion date: The Turkish Feeding/Swallowing Impact Survey (clinicaltrials.gov) - Aug 17, 2017
P=N/A, N=117, Completed, Sponsor: Hacettepe University
Trial primary completion date: Jul 2017 --> Oct 2017 Recruiting --> Completed | N=150 --> 117 | Trial primary completion date: Nov 2017 --> May 2017
- | Trial completion, Enrollment change: Buspirone for Functional Dysphagia (clinicaltrials.gov) - Aug 11, 2017
P=N/A, N=10, Completed, Sponsor: The Cleveland Clinic
Recruiting --> Completed | N=150 --> 117 | Trial primary completion date: Nov 2017 --> May 2017 Enrolling by invitation --> Completed | N=20 --> 10
- | omeprazole / Generic mfg.
Enrollment change: Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis (clinicaltrials.gov) - Jul 28, 2017
P4, N=12, Completed, Sponsor: University of Louisville
Enrolling by invitation --> Completed | N=20 --> 10 N=15 --> 12
- | Enrollment change, Trial withdrawal, Trial primary completion date: Computerized Acoustic Swallowing Evaluation (clinicaltrials.gov) - Jul 25, 2017
P=N/A, N=0, Withdrawn, Sponsor: Cedars-Sinai Medical Center
N=15 --> 12 N=20 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Oct 2017 --> Jun 2017