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30 Companies |
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45 Products |
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45 Products |
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68 Mechanisms of Action |
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2 Trials |
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656 News |
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- New trial: A Prospective Pilot Study to Evaluate a New Marker of Ischemia in Chest Pain Triage (clinicaltrials.gov) - Nov 18, 2015
P=N/A, N=100, Not yet recruiting, Sponsor: Assistance Publique Hopitaux De Marseille
- Victoza (liraglutide) / Novo Nordisk
New P4 trial: GAP: Glucagon-like Peptide-1 and Coronary Microvascular Dysfunction in Women With Angina Pectoris and no Coronary Stenosis (clinicaltrials.gov) - Nov 14, 2015
P4, N=33, Not yet recruiting, Sponsor: Eva Prescott
- Trial completion: The Effects of Inorganic Nitrate on Cardiac Muscle in Angina (clinicaltrials.gov) - Nov 6, 2015
P2, N=70, Completed, Sponsor: University of Aberdeen
Recruiting --> Completed
- New trial: NOVA-SKIN: Novel Vitality Indices Derived From the Hexoskin in Patients Affected With Angina Undergoing Coronary Revascularization or Medical Therapy (clinicaltrials.gov) - Oct 30, 2015
P=N/A, N=30, Not yet recruiting, Sponsor: Montreal Heart Institute
- || Trial primary completion date: Antiplatelet Therapy Following Stent Implantation (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=900, Recruiting, Sponsor: Elpen Pharmaceutical Co. Inc.
Recruiting --> Completed Trial primary completion date: May 2015 --> Apr 2016
- rosuvastatin / Generic mfg.
Trial primary completion date: Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance (clinicaltrials.gov) - Oct 22, 2015
P4, N=66, Recruiting, Sponsor: Oslo University Hospital
Trial primary completion date: May 2015 --> Apr 2016 Trial primary completion date: Sep 2015 --> Sep 2016
- ||| New trial: Boston Scientific COMET Wire Validation Study (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=100, Not yet recruiting, Sponsor: University Hospital Southampton NHS Foundation Trust.
- New trial, MRI: Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=104, Completed, Sponsor: Samsung Medical Center
- ||||| Aimovig (erenumab-aooe) / Amgen, Novartis
New P2 trial: Treadmill Cardiovascular Safety Study of Erenumab (AMG 334) (clinicaltrials.gov) - Oct 22, 2015
P2, N=120, Not yet recruiting, Sponsor: Amgen
- Enrollment open, Trial initiation date, Trial primary completion date: SCA COP: Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=440, Recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Trial primary completion date: Sep 2015 --> Sep 2016 Not yet recruiting --> Recruiting | Initiation date: Jan 2016 --> Jul 2015 | Trial primary completion date: Jan 2017 --> Jul 2016
- Trial completion: Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain (clinicaltrials.gov) - Oct 22, 2015
P=N/A, N=77, Completed, Sponsor: Medical College of Wisconsin
Not yet recruiting --> Recruiting | Initiation date: Jan 2016 --> Jul 2015 | Trial primary completion date: Jan 2017 --> Jul 2016 Active, not recruiting --> Completed
- Trial completion, Enrollment change: Natural Ischaemic Preconditioning Before First Myocardial Infarction (clinicaltrials.gov) - Oct 3, 2015
P=N/A, N=16000, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=13000 --> 16000
- Trial completion, Enrollment change: Previous Cardiovascular Disease, Cardiovascular Risk Factors and Chest Pain in First Myocardial Infarction (clinicaltrials.gov) - Oct 3, 2015
P=N/A, N=9000, Completed, Sponsor: London School of Hygiene and Tropical Medicine
Active, not recruiting --> Completed | N=13000 --> 16000 Active, not recruiting --> Completed | N=2100000 --> 9000
- ranolazine ER / Generic mfg.
Trial primary completion date: EREDA: Effects of Ranolazine and Exercise on Daily Physical Activity Trial (clinicaltrials.gov) - Sep 24, 2015
P4, N=40, Recruiting, Sponsor: Duke University
Active, not recruiting --> Completed | N=2100000 --> 9000 Trial primary completion date: Dec 2015 --> Mar 2016
- Trial primary completion date, MRI: CARMENTA: The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=300, Recruiting, Sponsor: Maastricht University Medical Center
Trial primary completion date: Dec 2015 --> Mar 2016 Trial primary completion date: May 2015 --> May 2016
- Enrollment open: PERCEPIC: PERC Rule Combined With Implicit Low Clinical Probability (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=3000, Recruiting, Sponsor: University Hospital, Angers
Trial primary completion date: May 2015 --> May 2016 Not yet recruiting --> Recruiting
- ||| Enrollment closed, Trial primary completion date: ISAR-DESIRE 4: Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 4 (clinicaltrials.gov) - Sep 14, 2015
P4, N=250, Active, not recruiting, Sponsor: Deutsches Herzzentrum Muenchen
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Aug 2015
- | carvedilol / Generic mfg., atenolol / Generic mfg.
New P4 trial: Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris (clinicaltrials.gov) - Sep 14, 2015
P4, N=99, Completed, Sponsor: Gachon University Gil Medical Center
- Enrollment change, Trial withdrawal, HEOR: Hypnotherapy in Patients With Chest Pain & Unobstructed Coronaries (clinicaltrials.gov) - Sep 9, 2015
P=N/A, N=0, Withdrawn, Sponsor: Imperial College London
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Aug 2015 N=42 --> 0 | Not yet recruiting --> Withdrawn
- Trial termination, Trial primary completion date: KCPS: Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients (clinicaltrials.gov) - Sep 3, 2015
P=N/A, N=1500, Terminated, Sponsor: Kyoto Prefectural University of Medicine
N=42 --> 0 | Not yet recruiting --> Withdrawn Active, not recruiting --> Terminated | Trial primary completion date: Mar 2014 --> Jul 2013; Principle investigator resigned in 2013
- New trial: Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization (clinicaltrials.gov) - Sep 2, 2015
P=N/A, N=1000, Recruiting, Sponsor: University of Oulu
- New trial: EMPACT: The Evaluation and Management of Patients With Acute ChesT Pain in China (clinicaltrials.gov) - Sep 1, 2015
P=N/A, N=10000, Not yet recruiting, Sponsor: Yuguo Chen
- Enrollment change, Trial termination, Trial primary completion date: PHOENIX: Safety Study of Transmyocardial Revascularization (TMR) With Bone Marrow Aspirate (BMAC) for Angina Reduction (clinicaltrials.gov) - Aug 19, 2015
P=N/A, N=7, Terminated, Sponsor: Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.
Active, not recruiting --> Terminated | Trial primary completion date: Mar 2014 --> Jul 2013; Principle investigator resigned in 2013 N=30 --> 7 | Recruiting --> Terminated | Trial primary completion date: Oct 2011 --> Mar 2012
- | Bystolic (nebivolol) / Menarini, AbbVie
Trial completion, Enrollment change, Trial primary completion date: NIRVANA: Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease (clinicaltrials.gov) - Aug 19, 2015
P4, N=12, Completed, Sponsor: Massachusetts General Hospital
N=30 --> 7 | Recruiting --> Terminated | Trial primary completion date: Oct 2011 --> Mar 2012 Recruiting --> Completed | N=70 --> 12 | Trial primary completion date: Nov 2015 --> May 2015
- Resolute ZES (zotarolimus-eluting stent) / Medtronic, Xience (everolimus-eluting stent) / Abbott
Trial completion, Real-world evidence, Head-to-Head, Real-world: The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente (clinicaltrials.gov) - Aug 12, 2015
P4, N=1391, Completed, Sponsor: Cardio Research Enschede BV
Recruiting --> Completed | N=70 --> 12 | Trial primary completion date: Nov 2015 --> May 2015 Active, not recruiting --> Completed
- | Trial completion, Enrollment change, Trial primary completion date: Use of Atropine in Tredmill Stress Testing (clinicaltrials.gov) - Aug 12, 2015
P3, N=103, Completed, Sponsor: HaEmek Medical Center, Israel
Active, not recruiting --> Completed Recruiting --> Completed | N=150 --> 103 | Trial primary completion date: Dec 2008 --> Oct 2009
- Resolute ZES (zotarolimus-eluting stent) / Medtronic, Xience (everolimus-eluting stent) / Abbott
Trial completion: DUTCH PEERS: DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population (clinicaltrials.gov) - Aug 12, 2015
P4, N=1811, Completed, Sponsor: Cardio Research Enschede BV
Recruiting --> Completed | N=150 --> 103 | Trial primary completion date: Dec 2008 --> Oct 2009 Active, not recruiting --> Completed
- ||| Enrollment closed: An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery (clinicaltrials.gov) - Aug 11, 2015
P4, N=236, Active, not recruiting, Sponsor: Biomet, Inc.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||| Trial completion, Enrollment change: Cardiogenesis Transmyocardial Revascularization Registry (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=204, Completed, Sponsor: Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | N=1000 --> 204
- | Trial completion: Magnetocardiography as a Tool for Patients Presenting With Chest Pain - Pilot Study (clinicaltrials.gov) - Aug 6, 2015
P=N/A, N=41, Completed, Sponsor: Quantum Imaging Limited
Active, not recruiting --> Completed | N=1000 --> 204 Not yet recruiting --> Completed
- Biomarker, Enrollment change, Trial withdrawal: ESTIMATE: Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department (clinicaltrials.gov) - Jul 21, 2015
P=N/A, N=0, Withdrawn, Sponsor: Biosite
Not yet recruiting --> Completed N=400 --> 0 | Terminated --> Withdrawn
- | Trial completion, Combination therapy: DEBIUT: Drug-eluting Balloon in Bifurcations Trial (clinicaltrials.gov) - Jul 20, 2015
P2/3, N=120, Completed, Sponsor: UMC Utrecht
N=400 --> 0 | Terminated --> Withdrawn Active, not recruiting --> Completed
- ||| Trial completion, Enrollment change, Trial primary completion date: Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study (clinicaltrials.gov) - Jul 10, 2015
P=N/A, N=60, Completed, Sponsor: Laval University
Active, not recruiting --> Completed Recruiting --> Completed | N=50 --> 60 | Trial primary completion date: Sep 2015 --> May 2015
- ||| Biomarker, New trial: Copeptin Registry (proCORE) Biomarkers in Cardiology (BIC)-19 (clinicaltrials.gov) - Jul 8, 2015
P=N/A, N=1000, Not yet recruiting, Sponsor: Charite University, Berlin, Germany
- Trial primary completion date: Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study (clinicaltrials.gov) - Jul 2, 2015
P=N/A, N=1000000, Active, not recruiting, Sponsor: University College, London
Recruiting --> Completed | N=50 --> 60 | Trial primary completion date: Sep 2015 --> May 2015 Trial primary completion date: Jul 2014 --> Aug 2015
- Trial completion: Pain During Chest Tube Withdrawal: Evaluation Using Pan Monitor (clinicaltrials.gov) - Jun 25, 2015
P=N/A, N=100, Completed, Sponsor: Hopital Foch
Trial primary completion date: Jul 2014 --> Aug 2015 Recruiting --> Completed
- | enoxaparin sodium / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date, Head-to-Head: VECOR: Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation (clinicaltrials.gov) - Jun 18, 2015
P3, N=62, Terminated, Sponsor: Eurofarma Laboratorios S.A.
Recruiting --> Completed N=502 --> 62 | Recruiting --> Terminated | Trial primary completion date: Dec 2013 --> Jul 2013; Change in strategy regarding the product by the company
- | Trial completion, Trial primary completion date: Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography (clinicaltrials.gov) - Jun 16, 2015
P3, N=284, Completed, Sponsor: Urmia University of Medical Sciences
N=502 --> 62 | Recruiting --> Terminated | Trial primary completion date: Dec 2013 --> Jul 2013; Change in strategy regarding the product by the company Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2015
- | NN1213 / Novo Nordisk
Trial completion: Tele-Electrocardiography in Emergency Cardiac Care (clinicaltrials.gov) - Jun 15, 2015
P3, N=794, Completed, Sponsor: University of California, San Francisco
Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2015 Active, not recruiting --> Completed
- ||| Trial completion, Enrollment change, Trial primary completion date: The PCI Choice Trial: a Pilot Randomized Trial of a Decision Aid for Patients With Stable Coronary Artery Disease (clinicaltrials.gov) - Jun 12, 2015
P=N/A, N=132, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=200 --> 132 | Trial primary completion date: Jan 2015 --> Mar 2014
- Resolute ZES (zotarolimus-eluting stent) / Medtronic
Trial completion: DEBfirst: Comparison of Drug Eluting Balloon and Drug Eluting Stent (clinicaltrials.gov) - Jun 12, 2015
P2, N=180, Completed, Sponsor: Seoul National University Bundang Hospital
Active, not recruiting --> Completed | N=200 --> 132 | Trial primary completion date: Jan 2015 --> Mar 2014 Active, not recruiting --> Completed
- || Trial primary completion date: Dan-NICAD - Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=2000, Recruiting, Sponsor: University of Aarhus
Active, not recruiting --> Completed Trial primary completion date: Jan 2016 --> May 2016
- Trial primary completion date: iFR Swedeheart: Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=2000, Recruiting, Sponsor: Uppsala University
Trial primary completion date: Jan 2016 --> May 2016 Trial primary completion date: May 2015 --> Sep 2015
- || Trial primary completion date: Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=681, Recruiting, Sponsor: Seoul National University Hospital
Trial primary completion date: May 2015 --> Sep 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- |||| Trial primary completion date: RENEW Study: Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina (clinicaltrials.gov) - Jun 11, 2015
P3, N=291, Active, not recruiting, Sponsor: Baxter Healthcare Corporation
Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Jun 2016 --> Nov 2015
- Trial primary completion date, Gene therapy: KAT301: EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease (clinicaltrials.gov) - Jun 11, 2015
P1, N=30, Active, not recruiting, Sponsor: Kuopio University Hospital
Trial primary completion date: Jun 2016 --> Nov 2015 Trial primary completion date: Mar 2015 --> Mar 2016
- eleclazine (GS-6615) / Gilead
Enrollment change, Trial withdrawal: GS-6615 in Adults With Chronic Stable Angina and Coronary Artery Disease (clinicaltrials.gov) - Jun 11, 2015
P2, N=0, Withdrawn, Sponsor: Gilead Sciences
Trial primary completion date: Mar 2015 --> Mar 2016 N=180 --> 0 | Not yet recruiting --> Withdrawn
- ||| nicorandil / Generic mfg.
Enrollment open: GzFFR: A Trial in Stable Intermediate Coronary Lesions and Grey-zone FFR Values (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=120, Recruiting, Sponsor: Golden Jubilee National Hospital
N=180 --> 0 | Not yet recruiting --> Withdrawn Not yet recruiting --> Recruiting
- || prasugrel / Generic mfg.
Trial completion, Trial primary completion date: Vasoactive and Anti-inflammatory Effects of Prasugrel in Acute Coronary Syndrome (clinicaltrials.gov) - Jun 11, 2015
P3, N=49, Completed, Sponsor: University of Cologne
Not yet recruiting --> Recruiting Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Jun 2015
- New trial: Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions (clinicaltrials.gov) - May 28, 2015
P=N/A, N=40, Recruiting, Sponsor: Ulsan University Hospital