Bone Marrow Diseases
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 186 Companies   244 Products   244 Products   91 Mechanisms of Action   17 Trials   2576 News 


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  • ||||||||||  Jakafi (ruxolitinib) / Incyte, Farydak (panobinostat) / Secura Bio
    Trial completion date, Trial primary completion date, Epigenetic controller:  Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial) (clinicaltrials.gov) -  Feb 13, 2018   
    P1/2,  N=18, Active, not recruiting, 
    Trial primary completion date: Dec 2017 --> Feb 2019 | Trial completion date: Dec 2017 --> Feb 2019
  • ||||||||||  azacitidine / Generic mfg.
    Enrollment closed, Trial primary completion date, Combination therapy:  A Study of LDE255 in Combination With Azacitidine for High Risk Myelodysplastic Syndrome Patients (clinicaltrials.gov) -  Feb 12, 2018   
    P1,  N=36, Active, not recruiting, 
    Trial primary completion date: Dec 2017 --> Feb 2019 | Trial completion date: Dec 2017 --> Feb 2019 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2017 --> Jan 2018
  • ||||||||||  Jakafi (ruxolitinib) / Incyte
    Trial completion date, Trial primary completion date:  Ruxolitinib for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) (clinicaltrials.gov) -  Feb 8, 2018   
    P1,  N=31, Active, not recruiting, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2017 --> Jan 2018 Trial primary completion date: Feb 2019 --> Feb 2020 | Trial completion date: Feb 2019 --> Feb 2021
  • ||||||||||  Promacta (eltrombopag) / Novartis
    Trial completion date, Trial initiation date, Trial primary completion date, Combination therapy:  Efficacy and Safety of Eltrombopag + CSA in Patients With Moderate Aplastic Anemia (EMAA) (clinicaltrials.gov) -  Feb 5, 2018   
    P2/3,  N=116, Recruiting, 
    Trial primary completion date: Feb 2019 --> Feb 2020 | Trial completion date: Feb 2019 --> Feb 2021 Trial primary completion date: Sep 2020 --> Sep 2022 | Trial completion date: Sep 2021 --> Sep 2023 | Initiation date: Mar 2015 --> Jan 2015
  • ||||||||||  Besremi (ropeginterferon alfa-2b) / PharmaEssentia, AOP Orphan Pharma
    Trial completion:  PEGINVERA: Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera (clinicaltrials.gov) -  Jan 30, 2018   
    P1/2,  N=24, Completed, 
    Trial primary completion date: Sep 2020 --> Sep 2022 | Trial completion date: Sep 2021 --> Sep 2023 | Initiation date: Mar 2015 --> Jan 2015 Active, not recruiting --> Completed
  • ||||||||||  Amevive (alefacept) / Astellas
    Enrollment change, Trial termination, Trial primary completion date:  Alefacept in Patients With Relapsed/Refractory Aplastic Anemia (clinicaltrials.gov) -  Jan 26, 2018   
    P1/2,  N=4, Terminated, 
    Active, not recruiting --> Completed N=56 --> 4 | Suspended --> Terminated | Trial primary completion date: Nov 2017 --> Dec 2011; Study drug not available at this time
  • ||||||||||  Enrollment change, Trial primary completion date:  Tissue Banking Study - Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients (clinicaltrials.gov) -  Jan 19, 2018   
    P=N/A,  N=131, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jan 2014 N=571 --> 131 | Trial primary completion date: Sep 2016 --> Jun 2016
  • ||||||||||  cyclophosphamide / Generic mfg.
    Trial completion, Post-transplantation:  Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT (clinicaltrials.gov) -  Jan 16, 2018   
    P2,  N=200, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2017 --> Jun 2014 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Enrollment change, Trial primary completion date:  Tissue Banking Study - Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients (clinicaltrials.gov) -  Jan 4, 2018   
    P=N/A,  N=571, Completed, 
    N=142 --> 19 | Suspended --> Terminated | Trial primary completion date: May 2019 --> Nov 2017; Sponsor decision based on portfolio prioritization Recruiting --> Completed | N=400 --> 571 | Trial primary completion date: Dec 2018 --> Sep 2016
  • ||||||||||  Trial completion, Enrollment change, Trial primary completion date:  Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer (clinicaltrials.gov) -  Dec 19, 2017   
    P=N/A,  N=16, Completed, 
    Phase classification: P3 --> P=N/A Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017 | Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017 | Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017
  • ||||||||||  lenalidomide / Generic mfg., azacitidine / Generic mfg.
    Trial completion, Trial primary completion date:  Lenalidomide Combined to Azacitidine in Intermediate-2 or High Risk MDS With Del 5q (clinicaltrials.gov) -  Dec 15, 2017   
    P2,  N=50, Completed, 
    Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017 | Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017 | Recruiting --> Completed | N=45 --> 16 | Trial primary completion date: Jun 2017 --> Sep 2017 Active, not recruiting --> Completed | Trial primary completion date: Mar 2016 --> Jul 2016
  • ||||||||||  Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
    Trial completion, Enrollment change, Trial primary completion date:  Fludarabine-Based Conditioning for Allogeneic Marrow Transplantation in Aplastic Anemia (clinicaltrials.gov) -  Nov 14, 2017   
    P1/2,  N=5, Completed, 
    Active, not recruiting --> Recruiting Active, not recruiting --> Completed | N=94 --> 5 | Trial primary completion date: Feb 2019 --> Nov 2017
  • ||||||||||  Trial completion, Enrollment change, Trial primary completion date:  PEG-MF: Interferon-pegyle α2a Efficiency and Tolerance in Myelofibrosis (clinicaltrials.gov) -  Nov 8, 2017   
    P=N/A,  N=62, Completed, 
    Recruiting --> Completed | N=51 --> 26 | Trial primary completion date: Jan 2018 --> Aug 2017 Recruiting --> Completed | N=100 --> 62 | Trial primary completion date: Sep 2017 --> Jan 2017
  • ||||||||||  ViraferonPeg (peginterferon-?-2b) / Merck (MSD)
    Trial termination, Trial primary completion date:  Pegylated Interferon Alpha-2b in Early Primary Myelofibrosis (clinicaltrials.gov) -  Nov 6, 2017   
    P2,  N=6, Terminated, 
    Recruiting --> Completed | N=100 --> 62 | Trial primary completion date: Sep 2017 --> Jan 2017 Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Jun 2017 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Jun 2017; This study was suspended due to insufficient subject accrual.
  • ||||||||||  Phase classification:  Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy (clinicaltrials.gov) -  Nov 1, 2017   
    P=N/A,  N=321, Completed, 
    Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Jun 2017 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Jun 2017; This study was suspended due to insufficient subject accrual. Phase classification: P4 --> P=N/A